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Query: [F] COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAQASDSIRFILNDSEIVLSDVAPTSTLLDFLRLERRLTGTKEGCAEGDCGACTVLVGRLAEDASGAKKLVYESVNACIRFTGSLNATHVVTVEHLAAADGTLHPVQQALVDFHGSQCGFCTPGIVMSLYGLWLADENPSRAAIEKALQGNLCRCTGYEPIVRAAEAAAAERPAALFDPVTRTREAVTARLHAMGQTETIVVRSGADCLIVPVDAADLAGVLADHPGATIVAGCTDVGLWVTKQMRSLNPVVFINGIAELQRIESSTAGLTIGAGVSYTAAHEALSSAYPSFGRLLDRIGGDQVRNMGTIGGNIANGSPIGDSPPPLIVLGATVTLRSKDGQRTLPLEDFFIAYGKQDRRPGEFVESLFVPALPADERFAAYKISKRRDEDISALLGAFRISLDGDRVKTARIAFGGMAATPKRAKTVEAALIGQAWTEETVRTAQAAFETDYQPITDWRATGAYRMLAAKNLLMRFFLESVGETVRLQRFEEVALast
1 -154.000[F] COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A  ali  100  1MAQASDSIRFILNDSEIVLSDVAPTSTLLDFLRLERRLTGTKEGCAEGDCGACTVLVGRLAEDASGAKKLVYESVNACIRFTGSLNATHVVTVEHLAAADGTLHPVQQALVDFHGSQCGFCTPGIVMSLYGLWLADENPSRAAIEKALQGNLCRCTGYEPIVRAAEAAAAERPAALFDPVTRTREAVTARLHAMGQTETIVVRSGADCLIVPVDAADLAGVLADHPGATIVAGCTDVGLWVTKQMRSLNPVVFINGIAELQRIESSTAGLTIGAGVSYTAAHEALSSAYPSFGRLLDRIGGDQVRNMGTIGGNIANGSPIGDSPPPLIVLGATVTLRSKDGQRTLPLEDFFIAYGKQDRRPGEFVESLFVPALPADERFAAYKISKRRDEDISALLGAFRISLDGDRVKTARIAFGGMAATPKRAKTVEAALIGQAWTEETVRTAQAAFETDYQPITDWRATGAYRMLAAKNLLMRFFLESVGETVRLQRFEEVA 495
2 -61.500[C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs  ali follow..  33  57.APEIMPLTLKVNGKTEQL-EVDTRTTLLDALRENLHLIGTKKGCDHGQCGACTVLVNG-------------RRLNACLTLAVMHQGAEITTIEGLGS-PDNLHPMQAAFIKHDGFQCGYCTSGQICSSVAVLKEPPERTADEIRERMSGNICRCGAYANILAAIEDAAGE.................................................................................................................................................................................................................................................................................................................................... 226
3 -55.300[C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs  ali follow..  24  5...............................................................................................................................................................................................................AYARAADLEAAVKLLSKTPNAKLLGGGTNLVDLMRENIEQPDALVDVTGLPLDRIEERPDGGLVIGATVRNTAVAPVVRDRYPLLAQAIVFGASGQIRNMATVAGNLMIATHPSDMCVALAALDAKVNVIGPSGARTIAFEEFHRLDIETDLQPGELITGIEIPPLGFARRSLYRKVRDRASYAFALVSVAAALEVDSGKVRNVRLALGGVAHKPWRATEAERVLAGANAGAESFRQAAEAELAPARGL----AHNEFKIELAKRTIVGVLGELAG............ 326
4 -9.730[C] KOG3049 Succinate dehydrogenase, Fe-S protein subunit  ali follow..  15  34.ATAPRIKKFAI--QTYEVDLNKCGPMVLDALIKIKNEVDSRRSCREGICGSCAMNINGGNTLACTRRIDTNLNKVSKIYPLPHMYVIKDLVPDGKQQYLQSIEEREKLDGLYECILCACCSPAVLMQAYRWMIDSRDDFTEERLAKLQDSLYRCHTIMNCTRTCPK........................................................................................................................................................................................................................................................................................................................................ 255
5 -9.680[C] COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)  ali follow..  14  2.....LMATIHVDGKEYEV---NGADNLLEACLS----LGLDI-CWHGACRQCAVKQYQNAEDTRG------RLVMSCMTPAS--DGTFISIDD--EEAKQFRESVVEWLMTNHPHDCPVCEEG-MTVMTGHSFRRYRFTKRTHRNQDLGNRCRCVRYYKDYADGTDLG----------------------------------------VYGAHDNVYFGRPEDGTLESEFSGNL-VEICPTGVFTDKTHSERYNRKWDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVN---HYFLCDRGRFGYGYVNLKD-----------RPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGE---ENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVGEDVTQTGARVALAVRQA............................................ 398
6 -9.220[C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit  ali follow..  14  22.DGAKNVREYRI--DTYYIDVDDCGPMVLDALNNIDPTLTLRRSCREGICGSCAMNIDG-------------TNTLACTKGMEEIKGTVKVSPTPAKEWKQSHEDRLKLDGLYECILCACCSPAVLLQAYRWLIDSRDEATGERLDNLEDP-CNCAQACPIAEIKKMMVERR................................................................................................................................................................................................................................................................................................................................... 258
7 -9.200[C] KOG2282 NADH-ubiquinone oxidoreductase, NDUFS1/75 kDa subunit  ali follow..  14  26.TAASNLIEVFVDGQSVMV---EPGTTVLQACEK----VGMQI-CYHGNCRMCLVEIEKAP-----------KVVAACAMPV--MKGWNILTNS--EKSKKAREGVMEFLLANHPLDCPICDQGGECDLFGNDRSRFLEGKRAVEDKNIGTRCRCIRFASEIAGVDDLG----------------------------------------TTGRGNDMQVGTYIEKMFMSELSGNIPVGALTSKPYA------FTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDIN---EEWISDKTRFAYDGLKRQRL--TEPMVRNEKGLLTYTSWEDALSRVAGML-------QSFQGKDVAAIAGGLVDAEALVALKDLLNR............................................................................................................ 360
8 -8.640[C] COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB  ali follow..  18  114.........................................ENNC---GCTKC---------------------IQAC-------------PVDAIVGATRAMHTVMSDLC----TGCNLCVDPCPTHCISLQPVAETPDSWKDLNTIPVRIIPVEHHA................................................................................................................................................................................................................................................................................................................................................ 192
9 -7.740[C] COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)  ali follow..  14  5IINVVHGTFTQLRSLVMIFGHAFRKRDTLQYPEEPVYLPPRYRGC---ACNLCA---------------------VAC---------VGCISLQKAETEDGRWYPEFFRINFSRCIFCGLCEPTTAIQLTPDFE......................................................................................................................................................................................................................................................................................................................................................................... 123
10 -7.430[C] COG1146 Ferredoxin  ali follow..  14  43.........................................YDKC---TCGIC---------------------FVTC---------RRVFDFDKKEGKVIVARPYNCMV------ACQTCMPTGAISFPDASYIKKLVAQNKIVKKAFEIIKPLLAEDHLSPKETETKPEP................................................................................................................................................................................................................................................................................................................................... 139
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 3 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;