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Query: [S] COG4713 Predicted membrane protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNKRVVKVEYIFMAFALFFGVLFAVINAPFQDPDEPIHFYRAYQISTGQMFEQKNNSGIGGYLPQNLIKTSENLSEDIKAKSNKKQDINKIKYYLNLPLNKNKVAFNDFRSATIYSDIVYIPQSIGINLAKIFRASALYMMYFGRIANLICWTIIVFFSVKLIPFKKNLMAFLALTPMNLYQAASLSADAMTNSMAFLSIALVLRYAFGEEEAKLTKRQIVTMIIAFTLLAFSKRIYFVMCILFFIIPIKKFNSKKDYIGTFVIMLGACLMSLVTVSVISKILAIKVSAGSYTPGQMEFVLSHPITYIHILLRTFHFKMSFYAISFIGVFGWLDTRLPLNLYLFYGVALVLIALFEHTLIEKNKDRIIMFIVFIINVGLIMSALYVSWTPKAANIIEGIQGRYFIPIIPLLGCFIGVKANKSRNVYSKVVLAISTFTILTYSVLQLLLRFYGIRILLast
1 -117.000[S] COG4713 Predicted membrane protein  ali  100  1MNKRVVKVEYIFMAFALFFGVLFAVINAPFQDPDEPIHFYRAYQISTGQMFEQKNNSGIGGYLPQNLIKTSENLSEDIKAKSNKKQDINKIKYYLNLPLNKNKVAFNDFRSATIYSDIVYIPQSIGINLAKIFRASALYMMYFGRIANLICWTIIVFFSVKLIPFKKNLMAFLALTPMNLYQAASLSADAMTNSMAFLSIALVLRYAFGEEEAKLTKRQIVTMIIAFTLLAFSKRIYFVMCILFFIIPIKKFNSKKDYIGTFVIMLGACLMSLVTVSVISKILAIKVSAGSYTPGQMEFVLSHPITYIHILLRTFHFKMSFYAISFIGVFGWLDTRLPLNLYLFYGVALVLIALFEHTLIEKNKDRIIMFIVFIINVGLIMSALYVSWTPKAANIIEGIQGRYFIPIIPLLGCFIGVKANKSRNVYSKVVLAISTFTILTYSVLQLLLRFYGIRIL 456
2 -18.900[G] KOG4123 Putative alpha 1,2 mannosyltransferase  ali follow..  9  10.RSPGDRHLSTYFCFAAVRLLLVFVPQLGYVHPDE---FFQSVEVMTGDHFRLEH---------------------------------------------NNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQGTYAYVVFPRLIYTLISFSNDYCLFRICRLFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQ-----EPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPYLLKIWYVSNVALTLFFGFI.. 474
3 -18.700[MU] KOG2515 Mannosyltransferase  ali follow..  11  6.PRKSLSVSFVWTFSILAVLRLTSASFRVIDDCDEVYNYWELHYLLYGY----------------------------------------------------GLQTWEYSPEYAIRSWFYIALHAVPGFLARGLGLSRLHVFYFIRGVLACFSAFCETNLILAVAVALHLTSVLFVNSGMWSASTSFLPSSFAMNMVTLALSAQLS----PPSTKRTVKVVSFITIGAVIGWPFSAALSIPFILLELVDLKGRFRHLFCRWFKAIFVALLITGICIT--------------------VDSLFYHRIQFWNIVKYNVLAKDGR--PDIYGTEPWFANLSLQHNIVLWFAMACGPLVLLAAFTNWINLDSFLDLSSVISPFYIWLFIF--------IIQPHKEERFMYPIYPVLCLAAAIGLDMSLKLMIQILCVYAIIGCLSIARILAIQNYNAPMII 405
4 -18.100[MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/PIG-B) involved in glycosylphosphatidylinositol anchor biosynthesis  ali follow..  11  1.......MRIWFWLAILVFRWWNALWVKTFFQPDE---FYQSLEVAHHFIF------------------------------------------------RYGFLTWEWTSAIRSALHPLIFAALYRVLQVLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFALVANWTLACSLVSIMNAYVGVRTFSNSLETTLTSIGFYYFSYYLKYENSSKKAYSSLLGFISVAAFACFIRPTNILVWIFPLLFWNKNPQTPIKDLLSFSNVFNRFRFLYALGYGRLFGIFV-----LCVSLFLVNIIADRILYGRFVFPIISFFQFNVTSGLSSLYG------AWHYYLSQALPLICGGFLPFVLLTMDLQTAGTILCVFFPYSLI-------------------ELRFVYPISPILLTLAGKFFSSFSSWKRAARFFFLIGLGHALVITFL.......... 373
5 -16.200[O] COG4346 Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase  ali follow..  12  170.................................................................................................................EHPFLGKDIIALGMLIED----------FYWRIPGIIEHALIVIIVTLVAYKSSIAATFAALDPLLFATGIVAMLDIHVAFFIALFMLFLAL------------DRIRLSGIALGLAAATKLSGAFAFPILWFKILKEKDLKEYLISGLVLPMVSFLIPEITIIKAIGFIPWLEEFIASFSWHLSFKGEHPSEAPFWMWFVSLKPFPFHFDPDVYAVT------PILMISMIVFVFAVPYVSLRRKGLSEI---------FWMFWSIIAFFALQYILGGKTQFI-----YATPLIPPGAVALGVISYEIEYFERSLRIYLNYLRSIAKPLKKVIKR....... 477
6 -15.600[O] COG4745 Predicted membrane-bound mannosyltransferase  ali follow..  10  4SRDDSSPRVAAAVVAVTAAALLARLWA------DEARVADWTLQYMDLGAWQY---------------------------------------------------------RPIIHGPFLPHVNGVVFDV---FGAT-----FTMRLVVAVVGGLLPLTAWLYRTRVGALAVLLAANPVVLYYSRFMRNDLLLAGFMFTAVGLFVRFLDTHRA-----RYLYASAVPFALAFTTKLLYPLCWLGALALVTDDRMAVAGATDTSRLAVVRRAAARIRHRAWRAKAALAGSALTAPKPDLYRLFEQPGRAPAVLEAATIGTYHEFADLWASYVAFLSHDLSVLVACGTVVSVAAVVGYLANRYATETPRPLVSFAFYWGVFSVLGYPAVVDIAAAWTAV-----NALVPLAIPAAVGVGAVVRYGRRGAAAGDTAAVRLAVTVLVVSAAGMGAVAAET. 410
7 -15.500[S] COG5617 Predicted integral membrane protein  ali follow..  10  2..KRKLYYLTLATISVIEYIPLYLAPSPPALQINGNGHLFKVHKLMTSGWKPWIEDWYAG------------------------------------------------YPFLRFYPPLSYLTAGV-----GKVLGSDTKGYAATLMLTSFLGALALHHYLKSTGREPCISPLILLFPTVSYIEGNFP-RANAIHLAPLFLLSLYWLREKRE------RYLIASALGISIVALTHYSILPLLIITGILILWDDLRTMTALGNGIKVLGAVIGLTSFW------------------------------YVPFLFDKKWVEFWNISENKALFKSFSLNPTLLKSPFGILLILLLLIFAIFAIKNLVDRKKVILAGLYLYLSLGFYSPTTWLY---SFPLLSIV-RWFDLEALIIPLLIGESLKRVQRKSMVALVIIPFTVLAFMNVPKI.......... 359
8 -14.400[S] COG5305 Predicted membrane protein  ali follow..  9  47..................................................................................................................HPPLYFVLVHLWMKL----NQGELVSLLAARSFPALLGAVSIPLTYILGRLGQLAAGMMAVSPYAVYLGQEVRHYTLAMIWVIASLSCLVIATRHIQNRTLLPFWLIILWVGINALGIATHYFFTLTLCLVLIFLAWQQSTQAKTLVFFSPLWWRIYAVAAGTAVAGLVWLPSILENRYRSSLTAWIQVQGIGLHLINPIFQ-----AFAAWVTMIMLLPIESSQLAVVIASGLVMLIFAI-KFQLQQPQTSLATQVFIGVVLGAIALFFILTYI-FGVDITRG--ARYYFPAVIILVGASLAVYWQTSKKAVMIIWLMGFVSAVTVICNLGYQKYYRPDLL 400
9 -13.600[OKIT] KOG2642 Alpha-1,2 glucosyltransferase/transcriptional activator  ali follow..  8  23.........LLGASFSCIHVLLTTIVYHYVPEPDEIFHITQTRSYCSGNY---------------------------------------------------------SWNPLITTPPALYVISMPLCGGNERYALLFFAIPAFCRFRRMFVRVRIPTLKIYLKNTDLLTASIVGMLPILISSSILFYTDLLSLTSVIWGFSIGNPIAS------------AFLFLISILTRQTNIIWAAIYAFSVIASRIDKSRSKMENLKIIISTAFFYMVAFCAAHTWTQIIPNLLSHLRHLTDMKSLVLQAVVAVLVYYYSYDHPYLLADNRHFTFYIWRRFLANPTMRTTLAPLYVFSLRFMTTSTPSVHIFHKILFIIASLLVLVPAHL--------------FEMRYYIPYVLWRLS-----TVNNSRKSLLFLEIISQAVIFAANEFVQKLQQK..... 427
10 -12.500[S] COG5650 Predicted integral membrane protein  ali follow..  10  124.............................................................................................................TRYMEYPVLGGIFQWICGIITRFLYPESGLYFIVTALALAFFWVLVIRMMVELTGNRVWDTVLVAASPLVA-VHAFTNWDTPAIAAVIGAMLAVKR------------GNPLVAGVLIGAGTAFKL-WPLYLLGAYLVLAVKNKNLKPFITMAAAAAVTWLVV-----------------------NVPVMIAYPKAWNEFLRRGAEWTTIYQVIDRNLPINLNDPVLLNVLSFGLFGASCVAILILGLKVQRTPR--------VAELAFLIVAAFLLFNKV-------WSPQYSLWLVPLAVLAFPQWKVLFPWMVTDAMVWPILMWHMLMLDLIVISRDAFIVVM 443
11 -12.300[MU] KOG2516 Protein involved in dolichol pathway for N-glycosylation (mannosyltransferase family)  ali follow..  8  1.......MRWSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVF------------------DISQYDHLKFPGVVPRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGL-------TNGLSFIYLKNCLQDMFDEITEKKKEENESAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLTNVALGWV----------LLGRYNAAIFLSALVAIVFRLEVSALSAGIALFSVIFKKISLFDAIKFGIFGLGLGSAIS-------------------------ITVDSYFWQEWCLPEVDGFLFNVVAGYASKWGYFTHYLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQ---------------------EWRFIIYAVPSIMLLGATGAAHLWENMKVKKITNVLCLAILPLSIMT.......... 375
12 -12.200[M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family  ali follow..  8  1MKSVR---YLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMASGDWIVPHLLGL---------------------------------------------------------PIAGYWINSIGQWL---FGAN-----FGVRAGVIFATLLTAALVTWFTLRALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKG-KSAGFLLLGITCGMGVMTKGFLALAVVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLAIAQREPNFW----------HYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPW-------------LGLLPGALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLP--------------TYILSCFASLAMLMAHYALLAAKNNPLALRINGWINIAFGVTGIIATFVVSP... 365
13 -11.300[O] KOG2292 Oligosaccharyltransferase, STT3 subunit  ali follow..  8  1MNRTPKMLTFAILLIAWLAGFSSRLFA--IHEFDPWFNYRATAYMVQNGWYN-----------------------------------------------------------LNWFDERAWYPLGRIVGGTVYPGLMITSGGFLAPIFSGLTSISTYLLTKELWSAGAGLFSFIAIVPGYISVAGSYDNEGIAIFALQFTYFLWVRSVKTGSVFWSAAAALSYFYMVSAWGGYVFIINLIPLHVFVLLIMGRYSPRLLTSYSTFYILGLLFSMQIPFVGFQPIRTSEH-----------------MAALGVFVLLMAVATLRHLQSVLSRNEFRKLFIVGGLLVGVGVFVAVVVLTMLGVVAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTT-------FSFFFDLHILVCAFPVGVWYCIKQINDERVFVVLYAISAVYFAGVMVRLMLTLTP. 413
14 -10.600[S] COG5542 Predicted integral membrane protein  ali follow..  10  109.....................................................................................................................WAFSS--KIISFLAFRSKDVVLLGIVSCFASIFFHAIACYALYLLTKMTAYTVIFYCFSPSGIYMSVGYT-ESLFAAFSFLGLLLFIK------------KQQYPAAFLWSLATLIRSNGIFWCIFFGMPAIGTLKISLERLQLTFMQVSQLVGYGTKCLIILVPFFYNQYLGFKLFCPGVAWCNKSLPLIYPAVQEKY----------VGFLRYWTLNIPNFLFALLSIIPILFALFYSISGSTLHSFRSIKSHLVLSALYLYIGCFHMHTQV----------RMSSALPLLYWSMAHATLYAKSRNLKAFGHCILFVWIVYTVIAGLYGSFL..... 423
15 -9.880[R] COG1287 Uncharacterized membrane protein, required for N-linked glycosylation  ali follow..  10  17QKDWKIPLKVLILICIAVASVSSRLFS--IHEFDPWFNFRASILVEQGFY-----------------------------------------------------------NFLNWFDERSWYPSGIIFKVLHLLRINVNVCVLLAPAFSGITAIATYYLARELKSDACGLLAFMGIAPGYTSVAGSYDNEAIAITLLMSTFALWIKAVKSGSSFWGACTGLLYFYMVTAWGGYVFITNMIPLHVFVLLLMGRYTSKLYIAYTTYYVIGTLASMQVPFVGFQPVSTSEH-----------------MSALGVFGLLQLFAFYNYVKGLVSSKQFQILIRFALVCLVGLATVVLFALSSTGVIAPWTGRFYSLWDTNYAKIHIPIIASVSEHQPPT-------SSLFFDLQFLIWLLPVGVYLCFKELRNEHVFIIIYSVLGTYFCGVMVRLVLTLT.. 417
16 -9.430[M] COG3307 Lipid A core - O-antigen ligase and related enzymes  ali follow..  8  66.....................................................................................................................YLPAAMFVLLALSLLYQNNSYGPDMVGKYKKLLYILPLALFFMNQPRLIKLFCTGFLVANAVILAGSLAVG---FFMALAALLWLVLAFQHQGWKRWGYSVLVVAASYSILFLVLGRTGYVALIVGLGVWLFFSLGNRQRLTLVVLGALAFAALIFI--CMAASATDAADACNSSMGQRSAFIKESPIYENKEVDYKVNNPHNQYLLETIGVIG------------LFLFLAWVICCYRVIWQQTPALRNVLLAVLTSYMACNFFNSFLLDSSEGH---------LFMIFVAVLAGYSVSGSQSIAGKRL............................. 408
17 -9.160[S] COG4485 Predicted membrane protein  ali follow..  11  1MKSFLKTYRTYFISFIIPVVIMSGVYLSQSIYWDGFHQYVIFDVALR-----------------------------------------NILHGNSNLFYTFTSGLGLNFYALSSY----YLGSFLAPLVYFFDLTNMPDAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQILKLAL--STSYALMSFTVDVFIL-IPLIITGL--LLITEKKL-------LYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDFKTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAKQF-----------IGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIEALDLFWQ--GMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFLATIYL......... 397
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 1 0 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.