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Query: [S] COG4863 Uncharacterized protein conserved in bacteria, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKRENIKTILLTVLVVISLVFTWGIWTFQPNFSEGSSSTESTVRVKHKIEKTTQKLSETVRPRDMFIHDDGAHYKVDDNALYEEIWSDLPHWDVKGIKDISDQYDKAGFKSWFYGIGGSEAKLDLQFSDTIPIDIFQTLFKWSNQSFEYSSFDHILIPFNETKANKKIYLVSYSKQLILEVTVESANYRNIMNDLKNRQSNMPAFSLFSIGSKKEFLLPNKPLTMDKKEFVTESIKTNTFKQALFSDPSIVREDSNYNNRNVLTDGISRLDVNLSQRQVQFQQRNLVQSTSYQTGELIKKSQKYLEDTGSWTDHYQFFNINDSQQLSFYIFMDQIPVINSTAKPFGATSAITVQWANDDILSYKRPNYSLGTNPIKTSETELMGGSEVKMLLSKQTAYDTDKIDQIFLAYQLVSTSTNDDPLVELEPVWAMKVNGKIVPITKDLLRKEGANSGVELast
1 -130.000[S] COG4863 Uncharacterized protein conserved in bacteria  ali  100  1MKRENIKTILLTVLVVISLVFTWGIWTFQPNFSEGSSSTESTVRVKHKIEKTTQKLSETVRPRDMFIHDDGAHYKVDDNALYEEIWSDLPHWDVKGIKDISDQYDKAGFKSWFYGIGGSEAKLDLQFSDTIPIDIFQTLFKWSNQSFEYSSFDHILIPFNETKANKKIYLVSYSKQLILEVTVESANYRNIMNDLKNRQSNMPAFSLFSIGSKKEFLLPNKPLTMDKKEFVTESIKTNTFKQALFSDPSIVREDSNYNNRNVLTDGISRLDVNLSQRQVQFQQRNLVQSTSYQTGELIKKSQKYLEDTGSWTDHYQFFNINDSQQLSFYIFMDQIPVINSTAKPFGATSAITVQWANDDILSYKRPNYSLGTNPIKTSETELMGGSEVKMLLSKQTAYDTDKIDQIFLAYQLVSTSTNDDPLVELEPVWAMKVNGKIVPITKDLLRKEGANSGVE 455
2 -29.100[S] COG4853 Uncharacterized protein conserved in bacteria  ali follow..  11  27..................................................................................................................................................................................................................NKQLSDDPDTLGNETLEERLKADNISHPDLSSKPTSGAIFTTEQAAFTTKDVSDLTGQAITLKDNNKQIYS---VLQTPIKAGKKGNNPDFQKFMESDVYRGESYEFWNYDKDRTLTFNQLINNNMVLFDEA------GQIIFYLKDDRVISYEQTWMSKQDDLKDKTNL-MSSTDALEAVYQHGELKQDSDVVSATFGYYTTVQLPSGN---VYFPVWCFEVKHSGETSYVLVNAKDEQ..... 255
3 -5.210[R] COG4324 Predicted aminopeptidase  ali follow..  7  1MRGFRAGVLALSMAGAALL-VGYYYQSVTGHLSLMAQRQSLDEAIENARQAHDDRLARRLEDARAIRAYASRELELPDNHSYRVYANIKRPFAVWNVFAAPELS----------------KLKTWCFL--VGCVTYRGYYDRNAAQAYADTLRAWDVDVAGIPAYSTLGYFDDP----------------LLNTFVNLPEGELARLIFHELAHQVVYAKGDTAFNESFATAVETIGVERWLADAATPEVRAEYATYDARRVQFRALLLDYRNRLEALYASPVSDDEKRAGKRALFDSLRADYAKLKAGWGGYAGYFAQPLSNAHLGVVASYLQWVPAFTA------------YQRDGGDWARFYADVKAMARAPQAERTAALTALAP.................................................................... 353
4 -4.980[S] COG4902 Uncharacterized protein conserved in archaea  ali follow..  10  1MRKKLIGFGLLALGIFSLVLQGVAAYRGTPGPS--PVALAQVSYYAPLSDEEANSLLYMIEEEK----LARDVYLKLYNETGLIIFDRIAQSEQRHMDAV----------LMLIEKYNLTAPDTLNEIGVFENEELQNLYNELVEMGSQSVVDALKVGALIEEIDIKDL-------EEWLSKVDNEDIKVVFENLMDGSKNHLRAFTKVLADNYGIYTP............................................................................................................................................................................................................................................ 197
5 -4.840[U] COG4537 Competence protein ComGC  ali follow..  16  8LRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELS.......................................................................................................................................................................................................................................................................................................................................................................................................... 68
6 -4.760[D] COG3116 Cell division protein  ali follow..  1  33LRFGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRV...................................................................................................................................................................................................................................................................................................................................................................................................... 97
7 -4.680[M] COG3317 Uncharacterized lipoprotein  ali follow..  8  1MAYSVQKSRLAKVAGVSLVLLLA-----------SSDSRYKRQVSGDESYLDAAPLAELHAPAGMILPITTGDYVIPVTKGSGAVGKALDIRPPAQPLALVSGARTQFSGDTQVVSVIQAKNYPIEKRDDASQTLTTDWVNWNRLDEDEQYRGRYQISVKPQGYQQAVTVKLVNLEQ--LQRYSTEMMNVISAGLDKTATDAANAAQNRSAATMDVQSAADDTGLPMLVVRGPFNLVWQRLPAALEKVGMKVTDSTRSQGSMAVTYKPQVGDLDNRSSLQFIDPKGHTLTQSQNDALVAVFQAAFNK.................................................................................................................................................... 344
8 -4.660[S] COG2968 Uncharacterized conserved protein  ali follow..  8  23..........................................................................................................................................................................................................................................................AQAAEVPEGPHVVTSGTASVEATPDIATIAIVSAKDAADAKKQVDTRVAQYFDFLNKSGIEKKDVKAANIRTQPEYDYEAVLKGYRAVRQVQVTLRQLDKLALKSGLNEIRAVELGVASPETYREQARKKAIENTITQAGALADGFKVKLGPVYSIR................................................ 192
9 -4.640[L] KOG2405 Predicted 3`-5` exonuclease  ali follow..  8  8...........ALLFFMDHLMQKNGRRTIHDLSCQFGARGFSEEMRNAVGTTQEGLTEFLQGHPSLFTVEGDQVILNGHNDLNA-------------KNNPLLQSGIRSRNYEKEAVDFFVTKLTKFGPELQIKSLLGHRSQAAPEVRLVSGRHLKEFCEFLQSQVDYFVVEGDRVRLKNMPEPDENAIEMDDEGRPLAGVKAKQAAVEYLKSVLEQNEDQPIPLDQFYQNFCQRFSHTIRQDVATNPKELLQFLKLNRGLFFIRSNKVSLVKNRLNEDGSENGSDEGEETNNLDQSALTRIHFVKALKPAQDSRLWQDINNMEKKVVGLDLKTVTV---GVDGEIFLSLGVIATTSQ----GIFDLASSDVIILESGFKGILESEKVVKLLAHKYAVHMRNVFDTQVAHSLLQHEKFNKSL................................. 416
10 -4.640[C] COG3043 Nitrate reductase cytochrome c-type subunit  ali follow..  16  8MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQEGAIRMPKEQDRMPLNYQP--MIPHSVEGYQVTTNTNR...................................................................................................................................................................................................................................................................................................................................................................................... 89
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Rychlewski L, Ye Y, Jaroszewski L, Godzik A. Integrated web service for improving alignment quality based on segments comparison. BMC Bioinformatics. 2004 Jul 22;5(1):98.