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Query: [A] COG5176 Splicing factor (branch point binding protein), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSFRRINSRYFENRKGSSMEEKKAKVPPNVNLSLWRKNTVESDVHRFNSLPSKISGALTREQIYSYQVMFRIQEITIKLRTNDFVPPSRKNRSPSPPPVYDAQGKRTNTREQRYRKKLEDERIKLVEIALKTIPYFVPPDDYKRPTKFQDKYYIPVDQYPDVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEGKNASDLPPGAMNFEDPLHCLIIADSEDKIQKGIKVCQNIVIKAVTSPEGQNDLKRGQLRELAELNGTLREDLast
1 -113.000[A] COG5176 Splicing factor (branch point binding protein)  ali  100  1MSFRRINSRYFENRKGSSMEEKKAKVPPNVNLSLWRKNTVESDVHRFNSLPSKISGALTREQIYSYQVMFRIQEITIKLRTNDFVPPSRKNRSPSPPPVYDAQGKRTNTREQRYRKKLEDERIKLVEIALKTIPYFVPPDDYKRPTKFQDKYYIPVDQYPDVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEGKNASDLPPGAMNFEDPLHCLIIADSEDKIQKGIKVCQNIVIKAVTSPEGQNDLKRGQLRELAELNGTLRED 269
2 -65.600[A] KOG0119 Splicing factor 1/branch point binding protein (RRM superfamily)  ali follow..  47  38MSNGYRDSKSNSRMDHRPDGYHDGRGRRAYRKHYWGHPTPIEEMLP-MELETAVKSCMTMEQLELYSLNVRLEEITQKLRTGDVVPHH-RERSPSPPPQYDNHGRRLNTREIRYKKKLEDERHRIIERAMKMVPGFRAPSDYRRPAKTQEKVYVPVKDYPEINFIGLLIGPRGHTLKDMEAKSGAKIAIRGKGSVKEGKGRSDPSVR-GNMEEDLHCLVTADSEDKINHAIKLIDNVIQTAASVPEGQNDLKRNQLRQLATLNGTLRDD 306
3 -63.400[A] KOG1588 RNA-binding protein Sam68 and related KH domain proteins  ali follow..  16  118.QMVIAQSNAYDLLGHLQPDILKFIKQHNETFPTAQQQRMIDIRRQVDDVRQVMADNVERIMERGERLENMENRTEALRTSKNQASGGDQKLAQSESGVELKTLLQLIGKAIEAAPATDEPAEPELPRFMRNNDNYHDQRRQFV-VTLSEILMVPVEKYPKYNFVGRILGPRGMTVKQLEKETGCRIFVRGRASTTASNPESKIISRNALTEEPLHVYIECQDTQSAAQAKMAVEVIQRLLSPPKDGKDELKRQQLVDISLINGTYRVT 400
4 -32.900[A] KOG1960 Predicted RNA-binding protein, contains KH domains  ali follow..  13  1MTEDNDEA---RVPLSDSSTTNDASRTRQRRKRKWDKPAEQSMSPLLQTLSVPLAVPKVNQDEVIIAREIVINDAEASLRRGKYRPPNAPPDGEKPLYLHISAAAQLQLKETTERILAVDRAAAMIEEMMKQKSISQIGSVGLQTVKLSTCVYLGFEADPSSNVAARIRGPNDQYINHIMNETGATVVLRGRGS------GSLENQHGDEAQLPLHLLLSGSNPKSIDDAK---RLAENLMDTISVEFGASRVSSSKVYGAVPPP.... 297
5 -12.400[R] COG1094 Predicted RNA-binding protein (contains KH domains)  ali follow..  19  109..................................................................................................................................................................RQKGRVIGREGITRRIIHDMTGVDISVYGK------------------------VSLIG-EFEKLAVAREAIEMILNGARHLEKKKQELKMKEFQEGAKL....... 190
6 -12.400[T] KOG2279 Kinase anchor protein AKAP149, contains KH and Tudor RNA-binding domains  ali follow..  16  65..................................................................................................................................................EVCLKIVVD-------EHVPLIMGRGGSNIKLIEEKTLAKIRLRDKDSGHK-------------------CDISG-VPDAVKAARALLIKEVKVELQVPQRL---GGELLQEIRSSSLA.... 168
7 -11.800[AR] KOG2191 RNA-binding protein NOVA1/PASILLA and related KH domain proteins  ali follow..  23  424..................................................................................................................................................KDVVEIAVPENL------VGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNR--------------VTITG-TPAATQAAQYLITQRIT.............................. 496
8 -10.900[O] KOG3273 Predicted RNA-binding protein Pno1p interacting with Nob1p and involved in 26S proteasome assembly  ali follow..  10  184..................................................................................................................................................................RAIGRIAGQGGKTKFAIENASRTRIVLADS------------------------IHILG-GFTNIRIAKDAVVSLIL---KVYANLRNAAARAKERI.......... 258
9 -10.700[R] COG0724 RNA-binding proteins (RRM domain)  ali follow..  10  6..........................................................................................................................................................PEEIIENADGSRSIITYKIEDGVKYKITQKVKEVKVLEKVHKSVAERKNWHKYGSEKGSP--------------AGPSAVTARLGEEVELRLSRNWKQAEEERIQKEKASLTKT. 105
10 -10.100[R] KOG2113 Predicted RNA binding protein, contains KH domain  ali follow..  10  46..................................................................................................................................................NVTESVEVPTSEH-----VAEIVGRQGCKIKALRAKTNTYIKTPVRGEDP--------------------FVVTG-RLEDVNEAKREIDCAAESYVRVPLRV---KGATIKRIQQDTHT.... 168
11 -9.400[AR] KOG2193 IGF-II mRNA-binding protein IMP, contains RRM and KH domains  ali follow..  12  195..................................................................................................................................................DIPLRLLVP-------QYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEK----------------ISVHS-TPEGCSSACKMILEIMHKEAKDTKTADEVP-RNLKKVEQDTET.... 308
12 -9.060[AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain proteins  ali follow..  12  576..................................................................................................................................................RSTLEVVLPEAV------VPKLVTKSRNKLAQISEWSGASVTI---------------VEDRPEETQNI-IRISG-TPEQAERAQSLLQGFIL.............................. 645
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 3 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;