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Query: [R] COG5633 Predicted periplasmic lipoprotein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRKGCFGLVSLALLLLVGCRSHPEIPVNDEQSLVMESSLLAAGISAEKPVLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAHSAVTLYGSANFLGAHKVRLYLYLLast
1 -68.300[R] COG5633 Predicted periplasmic lipoprotein  ali  100  1MRKGCFGLVSLALLLLVGCRSHPEIPVNDEQSLVMESSLLAAGISAEKPVLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAHSAVTLYGSANFLGAHKVRLYLYL 125
2 -13.400[R] COG3417 Collagen-binding surface adhesin SpaP (antigen I/II family)  ali follow..  12  1MKK-SVIALLGLAVILGGCSNKVSYGDAQAVETVIAAEMVDSMMMSGSVSAITRDGRPIVFVRIKNKTSEHIDTEISTKMLNSGKFRFVDMDRVEAVRMLYGNLSSIVKNAGSDKDVYYKMTMRL 169
3 -13.400[N] COG5567 Predicted small periplasmic lipoprotein  ali follow..  12  1MKNVFTLAVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKKVDSQTQSTMPDKNDRA..................................................................... 57
4 -13.100[S] COG3014 Uncharacterized protein conserved in bacteria  ali follow..  6  1MKIFVLLMSVILGISLTGCIGYRMDLEHFNT--LYYEESPKKAYEYSKQFTKKKKNALLWDLQNGLSALYARDYKTSLGVLDQAEQRFDKTQSAFTRGAGYVGATMINDNVRAYGGNIYGVLINY 124
5 -12.900[M] COG2980 Rare lipoprotein B  ali follow..  11  1MRYLATLLLSLAVLITAGCGRDTTQVPSTMKVMILDSGDPNGPLSRAVRNQLRLNGVELLDKETTRKDVPSLRL------------------------GKVSIAKDTASVFRNGQTAEYQMIMTV 104
6 -12.700[S] COG4259 Uncharacterized protein conserved in bacteria  ali follow..  8  4PKTLSRLSLCAAVLALTACGGNGQKSLYYYGG----PDTVYEGLKNDDTSLGKQTEKMEKYFVEAGNKKMNAAPGAHAHLLSRSGDKEGAFRQFEEKRLFPESGVFMDFLMKTGKGGK....... 122
7 -12.500[R] COG3218 ABC-type uncharacterized transport system, auxiliary component  ali follow..  11  8QKRRALFLAPLFAALMAGCAGAPNNDTVSSAAVTQGPSLKSRQLLIADPTALKALDSENI---VVRLSGSEVQYLGNSQWSDRLPRMVQSK------AFEDTGKLGGVGRPGQGLAIDYQVVSDI 130
8 -12.200[MP] COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance  ali follow..  11  2VKKAIVTMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS---IETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTDSKGEKSYYRAKGDALEMLDREGNPIES....... 129
9 -12.100[M] COG3056 Uncharacterized lipoprotein  ali follow..  16  36FKK--ILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVTVSINGADQRTDQALAKVTLTASRDLRFLLQEVLE-MTARGYMVGPNGPVNQIIVSQLYADVSQGNVRYNIATKADIAIIA 167
10 -12.000[S] COG3126 Uncharacterized protein conserved in bacteria  ali follow..  8  8.ALWQIVGGAALAVSLTGCAHQSAEAPVAAPISTATVATVHGTVNIRERVALPPDAVVTVTLSDISLADAPSRVIAQKAV-EGKQAPFTYSLPFNPSDIQPNARVIVSAAITRNGQLLF...... 132
11 -12.000[S] COG5608 Conserved secreted protein  ali follow..  18  1MGKAIIGIIFLSWLLYSAYFVMNFSP----------------TVRGEWGPMEGNNVEIIFHVDLGNPSPIPVAVQ-----LSLAGVEIGRIEQAKIGIFERSTNVVAV................. 92
12 -11.600[S] COG4939 Major membrane immunogen, membrane-anchored lipoprotein  ali follow..  11  3LKKVAITVVMASSLLLVGCGSSDDSSKDKKSTDTKQTETKKTAKTDGTMTFDDKGWKGFMSIEVKDGKITKANYD-----KNKDGKLKSEDADYSDSLVKGQSASSVEVVSGATHSSD....... 147
13 -11.000[M] COG3065 Starvation-inducible outer membrane lipoprotein  ali follow..  15  9NHKWMYGWLGLGALLLSGCVTIPPAIQGTTATPLQDLNLIRSAPKLFIGQEARFGGTV---VNVKNEPNRTR-LEIASVPLDSGARPILGEPSQGRVIAYRGHLVTVVGPIVGVEAGKI...... 133
14 -10.800[S] COG4925 Uncharacterized conserved protein  ali follow..  16  10IKWMLCLGVFLLAILATGCIEQNNIDQRAISNQSEMNSSEKTVSTEPEHGLALSEMSVKITS............................................................... 72
15 -10.600[R] COG5401 Spore germination protein  ali follow..  18  1MLKVIGATCLTSALLLSGCGLFQSDKAAEEIDPPQDVTFVNDEAGANSNTTAAKKTESEKSDT-AKADQASSTVMRELYLIDKNGYVVAQT.................................. 94
16 -10.600[P] COG4454 Uncharacterized copper-binding protein  ali follow..  5  1MTRLKLALLLTALATPAFAGEPGDKSKVTQTIQVTMKETPDGKMMFTPAKFEFKKGK-TVRFAVKNVGELDHEFILDEQKANLEHKAVMAKAP-NAISLAPGESGEIVWKFTNDGMFEFACLK.. 141
17 -10.500[R] COG3042 Putative hemolysin  ali follow..  14  1MKI--ISFVLPCLLVLAGCSTPSQPEAPKPPQIGMANPA--------SVYCQQKGGTLIPVQTAQGVSN-------------PGGETIDEWALWR.............................. 76
18 -10.500[N] COG5461 Type IV pili component  ali follow..  11  29GLPVLPVLAVAMTALLVGCAQRDSITVGTNHPIVIAEKNQKIDLPVRGMTGSQRDTLLGFLDGYDKSAAPTLTIQIPSGSANEVAATAAGRDFARLAVASGVKRNRIVVVSYQAGSSETSAPVRV 164
19 -10.400[S] COG4808 Uncharacterized protein conserved in bacteria  ali follow..  13  8FNKLFLVVASVLVFSLAGCGDKEESKKFSANL-KVLKQSSETKIQFASIGATTKEDAAKTLEPLSAKYKNIAGVEEKLTYTDTY......................................... 105
20 -10.100[R] COG2823 Predicted periplasmic or secreted lipoprotein  ali follow..  15  1MKALSPIAVLISALLLQGCVATKAATDPRSVGTQVDDGTLEVRVNSALSKDEQIKKEARINVTAYQ........................................................... 76
21 -10.000[S] COG4885 Uncharacterized protein conserved in archaea  ali follow..  7  1MNEKVVVAAIVIIIASAIAVAVTASKFESYARFG----------DIDMKLEAVNDSHAVVTFVTEVRKENVEEFAIKAKIYDIQTDLLLNELEETFKSPESRFTAELTIPF--EKTRDYKIVLYL 113
22 -9.970[S] COG3111 Uncharacterized conserved protein  ali follow..  12  1MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNTTVESAKSLRDDTWVTLRGNIVERISDD-----LYVFKDASGTIN-DHKRWNGVTVTPKDTVEIQG................ 109
23 -9.580[S] COG3009 Uncharacterized protein conserved in bacteria  ali follow..  11  1........MTIAALWLAGCSSGEINKPVVQSGTQSTASQGNRLLWVEQVAVP---DYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVAN-----STQLPGWVVASQPLGSAQDTLNVTV 115
24 -9.480[C] COG3241 Azurin  ali follow..  12  1MKA-YLALISAAVIGLAACSQEPAAPAAEATPAAEAPAESNDNMQFNTKDIQVSKACKEFTITLKHTGTQPKTSMGHNIVIGKTEDMDGIFKD-HTKLIGGGEESSLTLDPAKLADGEYKFACTF 168
25 -9.000[M] COG3133 Outer membrane lipoprotein  ali follow..  12  1MIK-RVLAVSLMGLSLAGCVNNDSLSGDVYTASEAKQVQNVTYGTIVNVRPVQAGGVAGQGVQSAMNKTQGVELEIRK----DDGNTIMVVQKQGNTRFSAGQRVVLASNGSQVTVS........ 153
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.