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Query: [A] KOG0299 U3 snoRNP-associated protein (contains WD40 repeats), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSDPFFTRPEHRKRKARSATSKREKENQKLERNGPANEDLASISSESEFNGFEDEIDEENEDTYETAAEKRLRLAREYLDEVKNELVEDGGFDAKEVDRELLASRLKEDVLEKKGQMYLDYTSKINPDVKIETAQLRGRHMRPLVGVVAYENFVYSADKSGLIQKWEALQEKDTENRENDDHEIGKAIKLHFRPIKFSRSRRGENDHVKEITCLAISNDGRWIVTGGLDHRIVIRDSVTLEPQHCWKHHRDAVMGLAMRRGTNEMFSCSADRSIKVWSLDQMSYIETLFGHQDVIFGVDALARERCVSVGGRDRTSRLWKIVEESQLVFRSGGTSMKATAGYMEGSVDCVAMIDEDHFVTGSDNGVIALWSVQRKKPLFTYPLAHGLDPILAPGRHSAETSPDPVTIPPQPRWITSLAAIPYSNLFASGSWDGNIRLWKIAEGLRSFEPLTIATPLSVYGCINSLSLSLQGKGKQSEVRVFAACGRETRVGRWKTLRGIPNSGFVFNIPLTVIPSVTDGDEIDELast
1 -148.000[A] KOG0299 U3 snoRNP-associated protein (contains WD40 repeats)  ali  100  1MSDPFFTRPEHRKRKARSATSKREKENQKLERNGPANEDLASISSESEFNGFEDEIDEENEDTYETAAEKRLRLAREYLDEVKNELVEDGGFDAKEVDRELLASRLKEDVLEKKGQMYLDYTSKINPDVKIETAQLRGRHMRPLVGVVAYENFVYSADKSGLIQKWEALQEKDTENRENDDHEIGKAIKLHFRPIKFSRSRRGENDHVKEITCLAISNDGRWIVTGGLDHRIVIRDSVTLEPQHCWKHHRDAVMGLAMRRGTNEMFSCSADRSIKVWSLDQMSYIETLFGHQDVIFGVDALARERCVSVGGRDRTSRLWKIVEESQLVFRSGGTSMKATAGYMEGSVDCVAMIDEDHFVTGSDNGVIALWSVQRKKPLFTYPLAHGLDPILAPGRHSAETSPDPVTIPPQPRWITSLAAIPYSNLFASGSWDGNIRLWKIAEGLRSFEPLTIATPLSVYGCINSLSLSLQGKGKQSEVRVFAACGRETRVGRWKTLRGIPNSGFVFNIPLTVIPSVTDGDEIDE 524
2 -68.000[D] KOG0642 Cell-cycle nuclear protein, contains WD-40 repeats  ali follow..  11  266.......IVRKKALPDSGEDRDTKEALKEFDFLVTSEEGDNESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQY------KKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSSFIMGADEALESELGPGEAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPAL-----SVFNDIKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESN-------------------VDTTANSSCQINRVISHPTLSISITAHEDRHIKFYDNNTGKLIHS------MVAHLEAVTSLAVDPNGL-------YLMSGSHDCSIRLWNLESKTCIQEF-FEESIHDVAFHPSKCYIAS 769
3 -67.000[S] KOG0293 WD40 repeat-containing protein  ali follow..  14  207.............................................................EELQTLLPASVIIPEKRLECL---VENSLHIQRDSCVFHNTLDSDLSLYSDHQCGKHQ---------IPSQTAQILESHTDEVWFLQFSHNGLASSSKDQTAIIWEISADGHISLK------------------------HTLVGHHKPVIAILWSPDDRQVLTCGAEEVIRRWDVDSGDCVHMYEKGGISPISCGWYPDGQGIIAGMTDRSICMWDLDGREKECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREATVE-----------RLIEEEDMITSFSLSNDNKYILVNLLNQEIRLWNIEGDPKIVSRYKGH----------------------KRSRFIIRSCFGGYKQAFIASGSEDSQVYIWHRSTGKLIVE------LPGHAGAVNCVSWSPTNLH------MLASASDDGTIRIWGLDRINQQNQKVQGSSSNGVIHRCNGN.... 589
4 -65.400[A] KOG0285 Pleiotropic regulator 1  ali follow..  14  6................................................................REVETQSLKKLSLKSVRRAREIFSPVHGQFPQPDPESKRIRLCHKIQVAFGGVEP-----ASKPTRIADHNSEKTAPLKALALPGPKGSLRKSATEKALVVGPT-LPPRDLNNTGNPGKSTAILPAPGSFSAPWKNYRVLQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQI----------FVLPHDSDVFSVLARPTDPQVITGSHDSTIKFWDLRYGKSMATITNHKKTVRAMALHPKEPKGEFCHNMLSLQRDIINAVAVNEDG-VMVTGGDKGGLWFWDWKSGHQRAETIVQPGSLESEAGIYAACYDQTGS-------RLVTCEGDKTIKMWKEDED-------ATPETHPLNFKPPKEIRR. 476
5 -64.000[R] KOG0289 mRNA splicing factor  ali follow..  13  26....................................................................ER--RLIEKYIAENGTDPINNQPLSEEQLQLQTTRQELSHALYQHDAACRVIARLTKEVTAAREALATLKPQAGLIVPQAVPSSQVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVQVASHVGLHSASIPGILALDLCPDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD-------ETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNV--------------------------ANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTL-----QLDNNFEVKSLIFDQSGT-------YLALGGTDVQI--YICKQWTEILHFEHSGLTTGVAFGHHAKFIA. 491
6 -61.500[S] KOG0296 Angio-associated migratory cell protein (contains WD40 repeats)  ali follow..  14  3..........................................................................EEEENQELYIAENEVEEVIKDNDKLMDQGVTEDEAEQEQN--------DTMNNMVMDMSVQGFFEHKDSVFSVSINPVHCASGGGDDLGYIWDITTGEQICQL---------------------------TGHKDSIVAIDWSFDGTYIATGGMDSQVRLWKSSTGFEFITAFETVDEIVWLSWHPKGLFLAAGCNDGSIWMWSLPSGKVVQVMYGHTAPVNAGKFIPPGKRLATVDDSGTLIVWNPATGAPECRMSDHRFDPGNEETAAGWTSFDCNAEGNVLFLGGSSGKVKVVNINSSHILASLEAQTESVEAIALCTALPSASLKFRKSLPHEQAVIDCKFLPNTPYLLTACADCVIRKWDVRSGQLLGE------YTGHQEPILCMAITPDGK-------RVVTGSDDTELLVFDCEH........................... 399
7 -61.500[R] KOG0645 WD40 repeat protein  ali follow..  13  1.........................................................................................................................................SGHTGRLWSVAAHPMLFATSSQDKSVRIYNSNTYNLVHVIDG--------------------------FHTRSIRRVAWRPIERVLAVASFDSVVSINEKDDWECTAALEGHENEVKCIAWSCNGNYLATCSRDKSVWIWEADEFDCLAVLQEHTQDVKVVTWHPTEDLLVSGSYDNSICFWRDDGDD-------WALTCQLQGHTNTVWALAFSPNGNTLASADNDGNVFLWIKISSNEDVATIDSTNILRPALQE----EWKQQTSLPHIHKGAVYTISWMNDA-TLCSAGGDGKIVVYQREKHDEALWHVAEQDHAHGVYEINSLEYLRDDR--------LLSGGDDGECRVWSFK............................ 322
8 -60.900[R] KOG1334 WD40 repeat protein  ali follow..  11  166.............DASTENQNTDSESSSEDVELESMGEGLFGYPLPRMCPRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQ----------------VLTALRQRQLGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRGLASSGDDLRVIVWDWVRQKPVLNF--------------------------ESGHDINVIQAKFFPNDSTLAMCGHDGQVRVAELINAENTKRVAKHRGPAHELALEPDSYKFLTSGEDAVVFTIDLRQDRVVTRENDKKVGLYTISMNPANYQFAVGGHDQFVRIYDQRRIDKKENNGVLKHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKG---------------------RNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEG-----DRGDIVNCLEPHPYLP-------VLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLN. 619
9 -60.900[K] KOG0263 Transcription initiation factor TFIID, subunit TAF5 (also component of histone acetyltransferase SAGA)  ali follow..  13  208................TGQSFERGDAQLQPVKLQQMPMDKEMEKIVEMDLEEEDMMHQNDPNNQSPKLLKEFRKLHEPNAEDAPSRDYIPLPPHKGVDILSEVEAVKDWS--------KRLHLGPRASLPSVCMYTFHHTNNNMNCAEFSPDSIACGFQESYIRLWSIKADKKSLPKSTS--------------VEDSDGSVRLLSHSGPVYGTTFSPDNKYLLSCSEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFGHYFATASHDQTAQLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGHSV---------RVFNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDIGTGRRI--------------------------KTMRGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDVFKTNYN------NPVSSSLTGSVVTPFSAKTSTFNEVNWSTSP--------------DQMVALYTKQTPIFNVSFTRRNLCLA. 639
10 -60.700[S] KOG0271 Notchless-like WD40 repeat-containing protein  ali follow..  12  13........................................................SEDENELGGSGILVPVDISTNELQILCNQLLGSSDDPVPISFFTTEGAEIVDSDFETTLKLVYQPQAVFRVRPVTRCSASIPGHGEPVISAQFSPDGLASGSGDQTMRIWDIELELPLHTC---------------------------KSHKSWVLCIAWSPDATKIASACKNGEICIWNAKTGEQIKTLKRHKQWITSLAWQPTCRLLASCGKDGNIFIWDTVQGTVVRCLSGHTASVTCLRWGGEGL-IYSGSQDRTVKMWRADDGVMC---------RNMTGHAHWINTLALNTDYALRTSCFEPSKRCIKPDTVEECQKVAQTRYEAALEIAGGENPKETKQSINRMTGHMQLVNQVVFSPDTRYIASASFDKSVKLWCGRTGKYL------ASLRGHVGPVYQVAWSADSR-------LLVSGSADSTLKVFELKTKSLYYDLGHGDEVFTVDWSPEGTKVVS 461
11 -60.600[Z] KOG0313 Microtubule binding protein YTM1 (contains WD40 repeats)  ali follow..  14  10...........................................................TDNKKYAVDDVPFSIPAASLSNIINKLLKDKNEFHKHVKGQFLRMPLDKHMEVENISSEEVVEIEYVEKCTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLE----------------------------GKSIMTIVGHTDVVKDVAWVKKDSLLLSASMDQTILLWEWNVEKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEIVTLSGHMEAVSSVLWSDAEE-ICSASWDHTIRVWDVGSGSLK----------STLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKD-----------------------GSLVSLSLTSHTGWVTSVKWSPTHEQLISGSLDNIVKLWDTRSCKAPLYDLA-----AHEDKVLSVDWTDTGL--------LLSGGADNKLYSYRYSPTTS........................ 419
12 -60.200[ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2  ali follow..  12  1........................................................................................................................MKIKLIDSRSFKVAKIFRENTDKINAIDFAPNGLISCSEDDQIVIYDCEKGTQSRTV---------------------------NSKKYGVDLIHFTHANNTASSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSLDKTLRLWDLRSPNCQGLM--HLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDKGPF----VTFKLNQEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTGY-----------------------PNNKGIPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSVLNG-----DHPGPVQCVQFNPKYM-------MLASACTNMAFWLPTSEEG.......................... 316
13 -60.100[S] KOG1409 Uncharacterized conserved protein, contains WD40 repeats and FYVE domains  ali follow..  10  1.....................................................................................................MAAIINQRVEQGESSMG---------GAKPALLHRITGHVARINDVILLSKDVWTASDDRSVRLYLKRDNDQFWPSHFMPVAPTSLYYSEETDFNSMTESRKWTCHAGPISGLGFALSSELIFSCSRDKSIVWHCSENSN---KMGSYLLENSCTAMVIDLPFVFVGDHGGHVTVLRIVDNQLVSKLSAHTNAITSLTWDGNKKVLYSGSSDHLIIMWDIGGGRGEA--------YELNGHNGKVTTLCAAPAAKRLFSADEHGKLMCWDMNCKRVETPEWKTSDCCQKCNQP--QRKVVGLRQHHCRTCGSAVCGSCCDNWTTYPPMGYETKIRICNDCNARQNFNLTPLAIPHEIHTGITAMHLQETLG-------LLVTSGQNRVIMIWDVRSVC......................... 408
14 -59.900[R] KOG0286 G-protein beta subunit  ali follow..  15  8...................................................................................RQEAEQLKKQIADARKACADVTLAEL----------VSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSLVSASQDGKLIVWDSYTTNKVHAI---------------------------PLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCR---------QTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHE------------------------SIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERV------GILSGHDNRVSCLGVTADGM-------AVATGSWDSFLKIWN.............................. 340
15 -59.400[S] KOG0295 WD40 repeat-containing protein  ali follow..  16  1.......................................................................MSLSERQKEEINRAIAEQNNGYSESFSVFLKESSLSENDIKP--------LGGILEKKWTTVLRLQRKVNDLESKLQESQREHGAPTRDKRQAADWIPRPPETQKL---------------------------TGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCV---------YTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAVECVEWAPDTA-----------YTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVL------FTLLAHENWVRGLAFHPKGK-------YLISVADDKTLRVWELSAQRCMKAIAHEHFVSTVAFHQTSPFVIT 391
16 -59.300[A] KOG0265 U5 snRNP-specific protein-like factor and related proteins  ali follow..  15  1.........................................................................MGTKRPNNSVILAQEAKRSKNDLMAYTNRDKALLESGVRRTSNLQAPI-------------MQLEGHEGEIFTAEFHPEGLLSSGFDRQIYIWQVYED--------------------------CENVMAMSGHSGAVMEAHFTPDGSHIFTCSTDKTLAFWDIATGQRQRRFKGHGNFVNSVQGSRRGQQLCSGSDDRTIKIWDARKKHAAHTLESP-FQVTAVCFGDTGEQVISGGIDNEVKIWDIRKQAVL---------HHLRGHSDTITGMSLSPEGDFILTNAMDNTLRVWDVRP----------------------YAPGERCVKVFQGHQHNLLRCAWSPGSDKITSGSADRHVYIWDVNTRRILYK------LPGHNGSVNAVDFSPKEP-------LILSGSSDKTLYLGEIDE........................... 347
17 -59.000[Z] KOG1523 Actin-related protein Arp2/3 complex, subunit ARPC1/p41-ARC  ali follow..  10  1.....................................................................................................................................MSLHQFLLEPITCHAWNRDRIALSPNNHEVHIYKKNGSQ--------------------------VKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFEAENSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKKASTPSEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVST--------------------------LKTEFLPLLSVSFVSENSVVAAGH-DCCPMLFIYDDRGATTEDRNTALETLHQNSITQVSIYEVDK---QDCRKFCTTGIDGAMTIWDFKTLES........................ 362
18 -59.000[S] KOG0308 Conserved WD40 repeat-containing protein  ali follow..  11  1.........................................................................................................MSSCVNTSQTGPKKKIS-------FIIRDEHEYSNRSAVSALQYDAQNLFTGGSDTIIRTWSVPHHKDAFSARGGVRSPGKN--------SPVQYQGSLEQHTDWVNDMILCGHGKILISASNDTTVKVWNIERDNKIDCIRTHKDYVSCLAYAPIVEKAVSASFDHNIFVYDINANKTVNNLIGCKDSIYSLATTPNLSLVLGAGTEKCIRLFDPRTNEKI---------MKLRGHTDNVRALVVNDDGTRALSAGSDATIRLWDIGQQRCIATCIAHEEGVWTLQVDSSFLYDFTKSQLLFKEEAPVKKLLLSEKDNSLWVGTWKSDIKRWSIRPSAQLSIGGDEELVIPGAPAIKKHAMLSDKRH-------VLTRDSDGNVALYDVLAARKIKDYGVVDENSRQVYIPSWFVVD. 454
19 -58.400[A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  14  198........................................................EANSLHLNTISRNGQLCLWE--CSLAPSDLEDAERPKIAPPQRKKEKKAVSDNESEDDVENVVEKDALKEESTKEADEPRKEQRDVQLTAANYNTRTLVVAFSSGAFYLYELPDVNMIHSLSISDYPISAALFNCTGEWQSEQYIMKQQGHSSEMTCIAYSSDGQFIATGGEDSKVKLWNTQSSFCFVTFSEHTSGVTGIQFSRNKKFLVSSSLDGTVRLWSVKTGKLLEIISGHEGPVVSIAFSPTSSTLVSGSWDKTVKIWNCLESNSE---------HETIDAVSDVTNVTFSPSGEEIAVATLSGNITIFDIKSAGQVTTIEGRNDLSAGRLET------DIITARKNAQANYFSTIEYSADGECILAAGKSANICIYHVREAIKKFEITQNHSLDGLNDFISRKHLSEFGNMALVEER--ELEGGRVAIRLPGVQRGDMSSRRQQEVRVFSVKFSPTGQAFA. 741
20 -58.300[S] KOG0310 Conserved WD40 repeat-containing protein  ali follow..  12  1..........................................................................................................................................................MAQPYLPAEKFLS----------------------------RKQETILLDEDEPAVVSSVRISPKKPYHVATTSSVRLTLYDTVVCEPLNLFSRFKKGVCSIDFRHDGRLLAIGGDEGKVRIFDVESKVALRVMQASQSTVKSVHFSPRGDTVFSMADDGKIKQYRVADTAYGV---NAVPIIEIQAHEDAIRCGAVSSNDHIVLTGGYDHKVRLWDIRSKEKSLEL---------------------------DCEHPVESVLFLPGEQLIATAA-GPIVKIWDTTTGRQLTA------LQAHYKTVTSLRLATNST-------CLLSAGIDRRVNAFRTTNYSLINSWSMPSPVLDIDVSRDDQTMA. 303
21 -58.300[U] KOG1332 Vesicle coat complex COPII, subunit SEC13  ali follow..  15  7.........................................................................................................................................................................................................TVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGLIADLRGHEGPVWQVAWAHPGNILASCSYDRKVIIWREENGTKSHEHAGHDSSVNSVCWAPHGLILACGSSDGAISLLTYTGEGQ-------EVKKINNAHTIGCNAVSWAPAVKRFASGGCDNLIKLWKEEEDGQ------------------------KEEQKLEAHSDWVRDVAWAPSTSTIASCSQDGRVFIWTCDDASSNTWSPKLLH--KFNDVVWHVSWSITAN-------ILAVSGGDNKVTLWKESVDGQWVCISQGSVSASVTEGQQNEQ... 322
22 -58.300[JT] KOG0643 Translation initiation factor 3, subunit i (eIF-3i)/TGF-beta receptor-interacting protein (TRIP-1)  ali follow..  14  5.......................................................................................................................................LLQGHERSITQIKYNREGLFTVAKDPIVNVWYSVNGERLGTY---------------------------MGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALL-KTNSAVRTCGFDFGGNIIMFSTDKQMVSFFDLDNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEVL---------VNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTF---------------------------RTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIHLAFEEEFGRVKGHFGPINSVAFHPDGK-------SYSSGGEDGYVRIHYFDPQYFEFEF.................... 323
23 -58.200[B] KOG0273 Beta-transducin family (WD-40 repeat) protein  ali follow..  13  104.....................................................TQQQASAAATEASAMAKAATMTPAAISQQNPPKNREATVNGEENGAHEINNHSKPMEIDGDVEIP------------PNKATVLRGHESEVFICAWNPVSLASGSGDSTARIWNLNENSNGGSTQLVLR-------------HCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT-FASCSTDMCIHVCRLGCDHPV---------KTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTG-----------------PATSNPNSSIMLASASFDSTVRLWDVEQGVCT------HTLMKHQEPVYSVAFSPDGK-------YLASGSFDKYVHIWNTQSGSLVHSYQGTGGIFEVCWNARGDKVG. 509
24 -58.100[S] KOG0316 Conserved WD40 repeat-containing protein  ali follow..  12  7.................................................................................................................................PTKEAHILKGHEGAVLAARFNGDGALTCGKDRTIRLWNPHRGILIKTY---------------------------KSHGREVRDVHVTSDNAKFCSCGGDRQVYYWDVSTGRVIRKFRGHDGEVNAVKFNDSSSVVVSAGFDRSLRVWDCRSHSVEPVQIIDTFLDTVMSVVLTKTEIIGGSVDGTVRTFDMRIGREMSDNLGQP-----------VNCISISNDGNCVLAGCLDSTLRLLDRTTGELLQVYKGHIS------------------------KSFKTDCCLTNSDAHVIGGSEDGLVFFWDLVDAK-------VLSKFRAHDLVNSIDVDFYLRLL-----KFFVAGDKRELPPEGRLYVDFQQILTSIDFVIYVSNSPFFF.... 339
25 -57.900[T] KOG0279 G protein beta subunit-like protein  ali follow..  16  2...............................................................................................................................AEGLVLKGTMCAHTDMVTAIATPVDNIVTSSRDKSIILWKLTKED----------------------KSYGVAQRRMTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLATGESTRRFVGHTKDVLSVAFSTDNRQIVSASRDRTIKLWNTLGECTISEADGHKEWVSCVRFSPNTLVIVSASWDKTVKVWNLQNCKLR---------NTLAGHSGYLNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLEAG---------------------------SIIHSLCFSPNRYWLCAAT-ENSIRIWDLESKSVVEDLKVDLKAETKVIYCTSLNWSADGN-------TLFSGYTDGVIRVWGIGR........................... 325
26 -57.700[T] KOG4378 Nuclear protein COP1  ali follow..  11  1...............................................................................................................................................MMSNLVEPSWLLAASGGDTVKLFDVSADSGDPCV-----------------------LSYTPSPGCAVNSVKWNHTNLVVASTGEDKKISLWRKNGQSLGTGGDSAEECLSAISFSKKGSRICSGGTGQIVKIWDLQRKLCIKKLKGHTSTITGVMYNCKDEHLASVSVGGDLIVHNLASGARATELKDPNG--QVVQFVHVLRLLDYSRSSRHLVTAGDDGTVHLWDTTGRSPKMSW-------------------------LKQHSAPTAGVCFSPSNEIIASVGMDKKLYTYDSGSRR-------SSSCIAYEAPFSSLAFGDNGY-------ILVAGTSNGRVVFYDIRGKPQLHAFSNSEDVTSLSWQTSKPVIVN 332
27 -57.500[S] KOG0282 mRNA splicing factor  ali follow..  10  156......VEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKK--EEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCY---------LPKKQIHVWSGHTKGVSAVRLFPLSLLSCSMDCKIKLWEVYGE--------------------------RRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNR-KVPYCVKFNPDEDKFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFK--------YIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKG---------------------HMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSR------FKAHDKVCIGAVWHPH------ETSKVITCGWDGLIKLWD.............................. 579
28 -56.700[S] KOG1407 WD40 repeat protein  ali follow..  17  10.....................................................................................................................................................................................................SLHSREYQGHKKKVHSVAWNSNGTKLASGSVDQTARIWNIESKAKDLELKGHTDSVDQLCWDPKHSDVATASGDKSVRLWDARSGKCTQQV-ELSGENINITYKPDGTHVAVGNRDDELTILDVRKFKPL----------HRRKFNYEVNEIAWNMPGDFFFLTTGLGTVEVLSYPSLKPLDT--------------------------LTAHTAGCYCIAIDPKGRYFAVGSADSLVSLWDISDMLCL------RTFTKLEWPVRTISFNYSGE-------YIASASEDLFIDIANVQTGRTVHQIPCRAAMNSVEWNPKYNLLA. 290
29 -56.500[R] KOG2096 WD40 repeat protein  ali follow..  12  6........................................................VVGIASVILGALIAVLFF--SYFRKRTSEVQSMAKAEPQDPIRNPKSNHPAPKKNHPKSQASDKNQNKR---HHPLDLNTLKGHGDAVTGLCFSSDGLATACADGVIRVFKLDDASSKSF--NRWEFTLQAHFHDLTCFLKFRFLRINLPAGGHPTAVAFADDASSIVVGKLPLPSIKWDHHHIHEKRSVLTISGATATYGTADGSVVIASCSEGTDIVLWHGKTGRNLGHVDTNQLKNHMAAVSPNGRFLAAAAFTADVKVWEIVYQKDGSVKEV-SRVMQLKGHKSAVTWLCFSPNSEQIITASKDGSIRVWNINVRYHLDE-------------PKTLKVFPIPLCDSGGNPLHYDRLSLCPEGKILAASH-GSTLQWLCAETGNVLDTAEK-----AHEGDITCISWAPKAITVERHAMVLGTSGDDKKVKLWEAPKSQ......................... 452
30 -56.500[A] KOG0306 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  10  200........................................................LSEEKRLITGASDSELRV------DIAYLQEIEDPEEPDPKKIKGSSPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMREGRDRVVNLAVDKTGLACHGTDSVLELFCILSKKEIQKKMDKKMKKARKKAKLHSSQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAAD-SIKIWNRSTLQCIRTMTCEY--ALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHI------QTLEGHHQEIWCLAVSPSGD-------YVVSSSHDKSLRLWERTREPLI-LEEEREMEREAEYEESVAKEDQ 732
31 -56.500[A] KOG0319 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  9  26.........................................................SANGQKLFSTCTNVVKVID---TASYTIGDPEDELRITCTAVDKNRNRLLVAYNNQIIREY-SIPLDPSTTKPELARTWKTIHTAPILVMEFNEEGLATGSADHIVKVWNLTEQQCTHTLKGP-SVVSAILFGKHEKLAPKKLVNTWKSHNSHITALLQVPDSRVVVALSRDQTMSIHETETQETLRVLPLY-ESIEGGAIGHNGN-LFTVGEEGVVKEFVIETAKLVRKKRIASSNLDHLAYDVVSNRFLAISAEQNLIILDFENLKRLYNTKTLDCQLIRGHTESVLSVVSPTWDTSLLASCSKDNSIIFWRLSTLVPVAAATGHANTVTALAISNTGLPKLTCSSTMVAHGKDVNCVDISESDALIATGGMDKLVKLWQVDTHKMQLGIAG--TLSGHRRGVGDVKFAKNSH-------KLASCSGDMTIKIWNISEKSCLQTIGHSCAVFRVIFARNDSQLIS 582
32 -56.400[U] KOG0276 Vesicle coat complex COPI, beta` subunit  ali follow..  15  2...............................................................................................................................PLRLEIKRKLAQRSERVKSVDLHPTWILASLYSGTLCIWNYQTQVMAKSFEVTELPVRSAKFVARKNYNTMDKVKVFEAHSDYIRCVAVHPTLPYVLSSSDDMLIKLWDWEKGACTQIFEGHSHYVMQVTFNPDTNTFASASLDRTIKIWNLGSPDPNFTLDAHQKGVNCVDYFTGGDYLITGSDDHTAKVWDYQTKSCV---------QTLEGHTHNVSAVCFHPELPIIITGSEDGTVRIWHATTYRLENT--------------------------LNYGLERVWAIGYIKSSRRVVIGYDEGTIMVKLGREIP-------VASMDNTGKIIWAKHNEIQTAN-------IKSIGADYEVTDGERLPLSVKELGTCDLYPQSLKHNPNGRFVV. 369
33 -56.400[Z] KOG0318 WD40 repeat stress protein/actin interacting protein  ali follow..  12  1..................................................................MAQPQPPAYEN--KNIYATLPRTQRGQPIVLGADPKGKNFLYTNGN---------SVIIRNIENPAIADVYTEHSCAVNVAKYSPSGIASGDASGKIRIWDTVNKEHLNEFQPIAGPIKDISWSPDNQSETGTSVGEISGQSKSINSADFRPARPFIVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLYDGTSSELVGEFPAHKGGVYALAWKPDSTQLLTCSGDKTCRLWTVESRELVSVADPSKPLRVVKGHNKPITVLGLSDDRSTIYTGSHDGVVTNWNSGSGSYTDYVVKLNCQPRGLAILRNENIQDQKKIFSLPIKYEASSIAVNADTSDVAVGGDDQKLHIYTLKGGVLEPKVE-----LDHLGAVTDVSYSPDLK-------YLVACDAHRKVVLYSVEEYKNKEWGFHSARVNTVAWSPNSLLVAS 550
34 -56.300[B] KOG0639 Transducin-like enhancer of split protein (contains WD40 repeats)  ali follow..  16  441.........................................................................................GGKPAYSFHVTADGQMQPVPFPPD--------ALIGPGIPRHARQINTLNHGEVVCAVTISNPTVYTGG-KGCVKVWDISHPGN----------------------KSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLATPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQL----------QQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPD---------------------------KYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGAS-------IFQSKESSSVLSCDISVDDK-------YIVTGSGDKKATVYEVI............................ 769
35 -56.300[R] KOG0322 G-protein beta subunit-like protein GNB1L, contains WD repeats  ali follow..  14  1............................................................................................................................MAVLPPDPVFSLRSPDMGAVNSLCFQESDLLAGTIKGSVFLWDLQTNRSALHF---------------------------EVGSDPITSLHHTPDR--LVTQEKGGTITMFSIGGSSYVNHLGFCRSALHTNTSKTNEQLLFYPCEESSIGVLHVTDAAAPTQILVPDDPCFKPFECASQLFLLAGYESGHFLTWDISSSVIL----------DVMELAQDATSVDYDPVTNRGIVGGPTDKLISFSYQRSS----------------------MQMQLGSELCIKNPGVNGVRIRPDQKVFASAGWDGRIRIFSWKSLRPLAVLTQH-----KNGGVMDLAFSSQQVAMWHAP-IMAAAGMDGQISLWDLYN........................... 323
36 -56.100[R] KOG0646 WD40 repeat protein  ali follow..  16  1....................................................................................................................................................MEITVIASSSIDEGIGSWDLKTGTEQLQFKPCASPAHGLTAVGEKFLASSQQAEVKSYPVEPIKALAANNEGTYLVGGGISGDIYLWEVATGKLLKKWHGHYRSVTCLVFSGDDSLLVSGSQDGSIRVWSLIRTLYEHNFNEHTMSVTDIVIDYGGCVIISSSEDRTCKVWSLSRGKLL----------KNIIFPSVINALALDPGGCVFYAGARDSKIYIGAINATS---------------------EYGTQVLGSVSEKGKAITCLAYCADGNLLISGSEDGVVCVWDPKSLRHV------RTLIHAKGSRKGPVNN------IQIVRKTIVANSNKTQVSWKSRGALIPPPL--EKYERPVEDTMDGIVTVD 362
37 -56.000[BK] KOG1063 RNA polymerase II elongator complex, subunit ELP2, WD repeat superfamily  ali follow..  11  131.................................SETDAMFASASSDGVVNVWDVSFPSQPSEECKVVCLDSICVDTKAIVTLS-----------AELPQNPGRFALALGGLDNKIKLY-----SGERTGKFTSVCELKGHTDWIRSLDFSLPLLVSSSQDKVIRIWKLVLVGDVGSWRREITYIEGPVFVSGTFTYQISVESVLIGHEDWVYSVEWQPPVISILSASMDKTMMIWRPEKKTCVGELSHCALGFYGGHWSPNSLSILAHGYGGAFHLWRNVSSQMQKVPSGHFAAVTDVTWARTGEYLLSVSQDQTTRVFSAWKNDEGNEAEDEHARPQVHGHDINCVAMVQGKGNHRFVSGAEEKVVRVFEAPLSPESHKLYGHGNELFSLCSDHKGVGTWKAVGRLQSHSLTVTHLEFSYDDTLLLSVSRDRHFSVFSIQRTDNGEVSHKLMAKVAHKRIIWACSWNPFGH-------QFATSSRDKTVKIWSVENDARLVLPPFGSSVTAVAWTGLDRNEKS 758
38 -55.800[A] KOG0268 Sof1-like rRNA processing protein (contains WD40 repeats)  ali follow..  9  1.......................................................................MKVKMLSRNPDNYVRETKLDLQRVPRNYDPALHPFEVPREYVRA------ATKLERVFAKPFLASLDGHRDGVNCLAKHPEKVLSGACDGEVRIWNLTQRNCIRTI---------------------------QAHEGFVRGICTRFCGTSFFTVGDDKTVKQWKMDGPDEEEPLHTILGKTVYTGIDHHWKEAVFATCGQQVDIWDEQRTNPICSMTWGFDSISSVKFNPIETLLGSCASDRNIVLYDMRQATPL----------KKVILDMRTNTICWNPMEAFFTAANEDYNLYTFDMRA-------------------------LDTPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSR-----EVYHTKRMQHVICVKWTSDSK-------YIMCGSDEMNIRLWKANASEKLGVLYNQKLKEKFQHYPHIKRIAR 392
39 -55.300[A] KOG0647 mRNA export protein (contains WD40 repeats)  ali follow..  13  5...................................................................................................NRSNTTSALGTSTAMANEK----------DLANDIVINSPAEDSISDIAFSPQQFSASSWDGKVRIWDVQNGVPQG--------------------------RAQHESSSPVLCTRWSNDGTKVASGGCDNALKLYDIASGQ-TQQIGMHSAPIKVLRFPSNTECIVTGSWDKTIKYWDMRQPQPVSTVMMPER-VYSMDNKQSLLVVATAERHIAIINLANPTTIFK---------ATTSPLKWQTRCVACYNEADGYAIGSVEGRCSIRYIDDGMQKKS-------GFSFKCHRQTNPNRAPGSNGQSLVYPVNSIAFHPLYGTFVTAGGDGTFNFWDKNQRHRLKG------YPTLQASIPVCSFNRNGS-------VFAYALSYDWHQGHMGNRPDYPNVIRLH-ATTDEEVKEKKKR... 365
40 -55.100[I] KOG0301 Phospholipase A2-activating protein (contains WD40 repeats)  ali follow..  14  7......................................................................................................................GDVPMETESMPQYTISHVIEAHKSDTKALAVTQGGLISGGRDETVKFWAKKGKQYTKTH------------------------AFEQPKGITVNSIAYAEDGWRLFVGRRDGTIAVFGPSQAEPYAIFNEHKQNVCCLHINEKATHMLSGSWDSNVIIWPITESFTTIVCPGHTLSVWALASFPDLNTYLSASADKTIRMWF-----------GDTTLSVFKGHTDVVRALVVLSSSH-FLSAGNDGHIIHWDVASASILRKFATQAHE---------------------------FIYSMTLSDSHILTTGEDGTLEFWAIDGGKDNLAIVSEAVIQLPTTNTWDAKVLLNSD--------IAVAGSDGRIYIMTTDKNRKDILDAFDAEVVAKLTAKTERMKQE 353
41 -55.100[S] KOG2106 Uncharacterized conserved protein, contains HELP and WD40 domains  ali follow..  10  282........................................................HPTDTNIIVTCGEITSLLRKLPLIRSKDYSRTRKAKVVLCVTFSENGDTITGD---SSGNILV-----WGKGTNRISYAVQGAHEGGISPLCMLRDLVSGGGKDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVLSGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPV-WDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKY-----TRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHV-FGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAP---SHIYGGHSSHVTNVDFLCEDSH------LISTGGKDTSIMQWRV............................. 716
42 -55.100[D] KOG0267 Microtubule severing protein katanin p80 subunit B (contains WD40 repeats)  ali follow..  13  2.......................................................................................................................................SLCGHTSPVDSVAFNSEEVLAGASSGVIKLWDLEESKMVRAF---------------------------TGHRSNCSAVEFHPFGEFLASGSSDTNLRVWDTRKKGCIQTYKGHTRGISTIEFSPDGRWVVSGGLDNVVKVWDLTAGKLLHEFKCHEGPIRSLDFHPLEFLLATGSADRTVKFWDLETFELI---------GTTRPEATGVRAIAFHPDGQTLFCGLDDG-LKVYSWEPVICRDGVDMGWSTL---------------------------GDFCINEGKFIGCSYYRNSVGIWVSDISE--LEPYGAVSEDKNECMVKRFSVLNDQSERDSTGGNLNVAQNPGSLKATLPLESGKVATM-VSEKQNAAYFGPAGDKYS. 347
43 -54.900[A] KOG0640 mRNA cleavage stimulating factor complex; subunit 1  ali follow..  10  2.........................................................RDEILDPSNLVKNREILYRLMISQLM----DGLEKFAMELSMLVKADQCAPSERLLHVMIAGMQTLSLAPEPHSYETAYVTSHKQACRAGAFSCDGVATGSVDASIKILDVERMLAKSAPEDIEPGR---------EQQGHPVIRTLYDHTDEVSYLEFHPKEHILASASRDGTVKLFDIAKPSKAHKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCFVSAQQHKAGVTCVKYSPTGKLYATGSYDGDIKIWDGISGRCINTIAEAH-------GGAAICSLEFTRNGKYLLSSGMDSLVYLWELCTSRPIQTYTGAG--------------------TTGKQEHQTEAVFNHTEDYVLFPDEATTSLCSWNSRNGCRLTLNSL-----GHNGPVRYITHSPNGP-------AFLTCSDDFRARFWYRRANNQ........................ 424
44 -54.800[R] KOG2394 WD40 protein DMR-N9  ali follow..  7  47.SSGLLHYAHGKTVTQVTIAQLKERAAPSTPTGTSSGYSASSGFRSATAR----GTGNGSRALSFVGGNGGGKSVSTSSRISGSFAASNSNTSMTNTNFDGKGTYLVFNVSD-------AIFICDLNSQEKDPVKSIHFSNSNPMCHAFDGHDLLIGLNSGDVYTVSLRQQ----LQDVSKKLVGALHYNKDG---------SVNNRQDRCTSISWTESTFPAIRDPTQFSVDKAKYSKSNPVARWHICQGSINSIAFSNDGAHLATVGRDGYLRIFDFLTQKLVCGGKSYYGALLCCSWSMDGKYILTGGEDDLVQVWSMEDRKVV---------AWGEGHNSWVSGVAFDSNWSRFGSVGQDTQLLLWDLEMDEIVVPLRRAPGGSPTYSTGSSDVPKLSPIIAHRVHTEPLSGLMFTQES--VVTACREGHIKIWTRPSESETQT---NSSEANPTTALLSTSFTKDNK-------ASLSSKIISGSTFKQ.............................. 556
45 -54.600[D] KOG1036 Mitotic spindle checkpoint protein BUB3, WD repeat superfamily  ali follow..  11  1............................................................................................................................MTTVTPSAGRELSNPPSDGISNLRFSNNSLLVSSWDKRVRLYDVSTNSLKGEF----------------------------LHGGAVLDCCFHDDFSGFSVGA-DYKVRRIVFNVGK-EDILGTHDKAVRCCLFCDVTGQVITGSWDKTVKCWDPRGASGPERVGTYLQPERVYSMSLVGHRLVVATAGRHVNIYDLRNMSQPE-------QRRESSLKYQTRCVRCYPNGTGYALSSVEGRVAMEFFDLSEAAQAKK--------------AFKCHRKSEAGRDIVYPVNSIAFHPIYGTFATGGCDGFVNIWDGNNKKRLYQ------YSKYPTSISALSFSRDGQ------LLAVASSYTEAIFVRSVNEIE......................... 341
46 -54.300[S] KOG4328 WD40 protein  ali follow..  9  36......AKRSRDDSKSFKKKKPKPASTPTVIRMSLRTRGLNPDSAGLPDGFSDFRMGSQITHNQPSPQKQSPRLLTQLVDTLLGIESKSCRGKLVKGEIGVVKDENESPMVEFSIPVKPEKIEFDLDLLTLEPQNVARVVPGRIFVVQFLPCEVAAGDKLGNVGFWNLDCGNE----------------------EDNDGIYLFTPHSAPVSSIVFQQNSSRVISSSYDGLIRLMDVEKSV-FDLVYSTDEAIFSLSQRPNDQSLYFGQDYGVFNVWDLRAGKSVFHWELHERRINSIDFNPQNPVMATSSTDGTACLWDLRSMG-----AKKPKTLSTVNHSRAVHSAYFSPSGLSLATTSLDNYIGVLSGANFENTCMIYHNN----------------------TSRWISKFKAVWGWDDSYIYVGNLSKKIDVINPKLK----RTVMELHNPLQRAIPCRIHCHP------YNVGTLAGSTAGGQVYVWTTK............................ 516
47 -53.600[U] KOG0277 Peroxisomal targeting signal type 2 receptor  ali follow..  15  2..............................................................................................................................SAVCGGAARMLRTPGRHGYAAEFSPGRLACATAQGTLLILDPDEA--------------------------GLRLFRSFDWNDGLFDVTWSENNEVLITCSGDGSLQLWDTAKAGPLQVYKEHAQEVYSVDWSQTRGEVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPIPGCFASASGDQTLRIWDVKAAGVRI---------VIPAHQAEILSCDWCKNENLLVTGAVDCSLRGWDLRN-------------------------VRQPVFELLGHTYAIRRVKFSPHASVLASCSYDFTVRFWNFSKPDSLLETVE-----HHTEFTCGLDFSLQSPT------QVADCSWDETIKIYDPACLTIPA...................... 323
48 -53.100[A] KOG1272 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  6  4..............SSEDNNLMEKVLPPVEQVLTWTLIQICMQESDVELETKVKKYLRGEGANLETLKDKKLKTQLASREKLYGKSAKAAA-KIEKWLLPAEAGYLETEGLEKTWRVKQTDIANEVDILSSRNQYDIVLPDFGPYKLDFTASGMLAGGRKGHLALLDMMNMSLIKEI-QVRETVRDVAFLHNDQFGRDGTELHCLKERGPVARLRFLKNHFLLASVNMSGQLHYQDVTHGGMVASIRTGKGRTDVMEVNPYNSVVGLGHSGGTVTMWKPTSQAPLVQMQCHPGPVSSVAFHPNGHLMATSGKERKIKIWDLRKFEEVQ-----------TIHSFHAKTLSFSQKGLLAAGTGSF--VQILGDSSGGSS-------------------HNYTRYMNHSMVKGYQIEKVMFRPYEDVIGIGHSMGWSSILIPGSGEPNFDSWV-------ANPFETSKQRREKE-----VHSLLDKLPPETIMLDPSKIGARPSRRKEKPSRGEIEAEKEVAIEAA 482
49 -52.900[U] KOG0771 Prolactin regulatory element-binding protein/Protein transport protein SEC12p  ali follow..  8  2...............................................................................................................................ASNQQPPSNLQTYGVPIYAVDWILEERSKITKDQDDDDDDGSSSSSYIVLSGGGGEGRSCRVDLHTNSLSEQPIGRRVIGTDLPYRMAIHPRQGGLICALPENIIEDDNEEESEKVVKELKDVGQQLSLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHASVKSLTFSESGKFLVSLG-APLCRVWDVNASAAIA--------SLSKEKDEMFASCRFSVDNSVAANTQRGGSIITWDTTSWRRRSS-------------------------KLIKRNNSISAFNVSADGKLLAVGTLEGDVLIIDSTKMQTNQIVKK-----AHLGLVTALTFSPDSR-------CLVSVSFDSRARLTVIKQKGEKRYLWVAALLFVLVYVVLYYLMVA 378
50 -52.800[R] KOG0288 WD40 repeat protein TipD  ali follow..  14  69...........KAQSRLSEQLVIEVAESRTSKAILQEKELLINDLQKELTQRREDCTRLQEELEEKTKTVDVLIAENLEIRSQLEEMTSRVQKAETENKMLIDRWMLQKMQD----------AERLNEANDLYEEMLAKLKANGLETLARQQVIVRRNEDGTDHFVESTI--------------------------PSTCANRIHAHEGGCGSIVFEYNSGTLFTGGQDRAVKMWDTNSGTLIKSLYGSLGNILDMAVTHDNKSVIAATSSNNLFVWDVSSGRVRHTLTGHTDKVCAVDVSKFSRHVVSAAYDRTIKLWDLHKGYCT----------NTVLFTSNCNAICLSIDGLTVFSGHMDGNLRLWDIQTGKLLSEVAGHSSAVTSVSLSRNGTRTLEICGTLRASGNRLASSCISPDDDYVAAGSADGSVHVWSLSKGNIV------SILKEQTSPILCCSWSGIGK-------PLASADKNGYVCTWT.............................. 515
51 -52.700[DO] KOG0305 Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits  ali follow..  11  1.....MDSGMRATCTVPEHFLPRKLSKQNLDRFIPNRSAKDFDFANYALTQGSKRNLDEVTSASRKAYMTQLAVV---MNQNRTRILAFRNKPKSLLSTNHSDSPHQNPKPVKPRRYIPQNSERV-------LDAPGLRDDFSLNLLDWGSANVLAIALGDTVYLWDASSGSTSELV-------------------------TIDEDKGPVTSINWTQDGLDLAVGLDNSEVQLWDCVSNRQVRTLRGGHE-SRVGSLAWDNHILTTGGMDGKIVNNDVRIRSIVETYLGHTEEVCGLKWSESGNKQASGGNDNVVHIWDRSLASSK---QTRQWLHRFEEHTAAVRALAWCPFQASLLAGVGDGKIKFWNTHTGACLNSVETGSQ---------------------------VCSLLWSQSERELLSGFTQNQLTLWKYPSMSKMAE------LNGHTSRVLFMAQSPNGC-------TVASAAGDENLRLWNVFGEPPKTTKKAASKKYPELFSHVNS.... 442
52 -52.700[R] KOG2444 WD40 repeat protein  ali follow..  10  4..........................................................................................................................................EFDNPPLCMKSNKDGLVVGFVDGSIRFYDTQQHEEEFQE------------------------IWKFQTKSSIRGVDLDEHKKRVYAVTKNRSLCVFDIDTGKRVRCIKCHRSVPTAICTLPKSQQLATADESGEVKTWNLDPNANIRKWQEQDEDINDLKVDVKSNLLATSS-DGTLGAYDLRKAKLKMRSELMHSE------------YSVCGTNRSVYVGGEDGYVEVFNLNEYGNLLE------------------------RVESGFEMGVNGIVELRSGLLGLTSQGSNRMRLLNVQPSKRLGYAGYHGDEKSDDDGIDAITISTDKST------VFTMISMSCTIKKWDMGPIIDEIPILRAQDAKSKKMRKTEGFFDG 335
53 -52.600[YU] KOG2445 Nuclear pore complex component (sc Seh1)  ali follow..  17  2........................................................................................................................................................................................................QPFDSGHDDLVHDVVYDFYGRHVATCSSDQHIKVFKLDNWELSDSWRAHDSSIVAIDWASPGRIIASASYDKTVKLWEEDPDQKLCTLNDSKGSLYSVKFAPAGLKLACLGNDGILRLYDALEPSDLLTSEMKVLSIPPANHLQSDFCLSWCPSRFEKLAVSALEQAIIYQRGK-----------------------DGKLHVAAKLPGHKSLIRSISWAPSYQLIATGCKDGRIRIFKITEKLSPLASEELSEHDDHNGEVWSVSWNLTGT-------ILSSAGDDGKVRLWKATYSNE........................ 338
54 -52.400[S] KOG0321 WD40 repeat-containing protein L2DTL  ali follow..  11  19..................TSRANNSLPPTPDSSPAAPSKKHKLYDFLESRGKIETPRKRIVFEKKPLLHKPVHIQKK--AQLCKELLIRQLGGSRSHPFSTKTSRHVGGRLNLETYY-------------SRPSECLMMLNQLPFCLGFANNELAVCTETGALELFDSRFYDRQNEENQ----------------PSARRIHGWLAHNNAIFSVNFSKDDSLLATSSGDQTSKVFDLSTQQCITRLGYHSHSVKQVNFCNDSPNLVSCSRDGSIIFWDMRTHGITHENSGRDCSITSATWLPQSTVISSCSANSALKLWDLRTVHTVRLPAATTPELTTSKRDFGVTNVCTSPDGERIYAASRDSIIYEYSSRHLNSGFCKTYKD--------------------PRLRISSFYVKLACSPDGATLACGGKTSGVVVFDTTRNCSSSAML----TGGHTKDVTAVDWSSEGQ--------LASISDDGSVRVWNSSLHGSAANLKNFSEIFYWGFSEK...... 490
55 -52.400[R] KOG0315 G-protein beta subunit-like protein (contains WD40 repeats)  ali follow..  14  2..................................................................................................................................................GDQQQLILATGGYDHTIKVWQAHTGNCIKTMRVETSQVNALDRTPDKESNCTAPVINFDGVQKNVTRLGFQEDGNWMFTAGEDHHVRIWDMIAAPPHSRIFDCEAPVNAACLHPNQVEIAMGSQNGSVFLWDVKSERHERIVPEVDASIQDVAISPDGRYLAAANNKGNCYIWSLTSQDQKM--STLRPNRKIPAHSRYILRCKFSPDSRLLLTTSGDGTVCIWKTDDFSKW--------------------------RELCIENYWVWDAAFSADSKWLFTASSDGIARLWKLQTKSSIRD------YTGHTKAITALSFKDEIP-------VKSTNISDVQSSAKPPTQRD-----NPPGTNNLAFFETVGRVAMN 351
56 -52.400[S] KOG0270 WD40 repeat-containing protein  ali follow..  12  6...NWVPRGFSSEFPEKYVLDDEEVERINQLAQLNLDDAKATLEEAEGESGVEDDAATGSSNKLKDQLDIDDDLKEYNLEEYDDEEIADNEGGKDVSMFPGLSNDSDVKFHEGEKGEDPYISLPNQEDSQEEKQEL---------QVYPSDNLVLAARTEDYLDIYVYDDGAGFHSSDIPVEEGDEADPDVARGLVRDPALYVHHEWLDYKVGSNSEEAANYAAIGTFDPQIEIWNLKKSKTGHITTHHTDAVLSMAHNKFRSVLASTSADHTVKLWDLNSGNAARSLAHSNKNVSSSEWHMNGSILLTGGYDSRVALTDVRISDE------SQMSKYWSAMAGEEIETVTFASENIILCGTDSGNVYSFDIRNNE-----------------------NRKPVWTLKAHDAGISTLCSNKFIPMSTGAMGEKTVKLWKFPLDDNTKGPSMVLSRDFDVGNVLTSSFAPDIEV----AGTMVIGGVNKVLKLWDVFTNRSKSFKSELENVQARAKEEAQKIGKS 537
57 -52.200[S] KOG0281 Beta-TrCP (transducin repeats containing)/Slimb proteins  ali follow..  13  1MEPDSVIEDKTIELMISNGTSSVIVSRKRPSEGNYQKEKFDQWSESDQVEFVEHLISRQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVR--TDPLWKGLSESRGWDQYLFKNRPTDGPPNSFYRSLKIIQDIETIESNWRCGRHNL-------------------------QRIQCRSENSKGV--YCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGL--MVTCSKDRSIAVWDMASAT------DITLRRVLVGHRAAVNVV--DFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLQAALDPASTLCLRTLVEHSGRVFRLQFDEF---------QIISSSHDDTILIWDFLNVPPSAQNTRSPSRTYTYIS........ 507
58 -51.900[R] KOG1539 WD repeat protein  ali follow..  13  81.........................................................................................................................GNEIAVFRRAHQVATWSKHVAKVDLLLVFGEHVLSLDVEGNMFIWAFKGIEEHLAPIGNLQLTGKFTPLQLWNINTKKMLYQFKGWGSSVTSCVSSPALDVVAIGCADGKIHVHNIKLDEEIVTFEASRGAVTALSFSTDGRPLASGGSFGVISIWNLNKKRLQSVIDAHDSSIISLNFLANEPVLMSASADNSLKMWIFDTND-----GDPRLLRFRSGHSAPPLCIRFYSNGRHILSAGQDRAFRLFSVIQEQQSRELSQRHISRRAKKLRLKETPIKGVFVSRNHLLLAILACAISACGNFAVVGTAGGWIERFNLQSGIGSYFDMSEKRRYAHDGEVIGVACDSTNT-------LMISAGYHGDLKVWDFKKRELKSQWDVGCSLVKIVYHRVNGLLA. 552
59 -51.600[S] KOG0772 Uncharacterized conserved protein, contains WD40 repeat  ali follow..  11  3......................................................................................................DNTAPKKNSEKKARVFDLQAMFAQTISNAPRTEEPTHVPQSVSVSSKSESGSSAVSDDEDDFMPDLPPGFQM--QQSEAGPSSSRAEGPEDKLIPAACEAKISHGTQAISALRVEPPGVRFASGGLDYYVKLFDFQKMDMSELLPAESHVINSLAFSPNGETLVVASGEAIIRLLDRAGKQWLNITKGHTATVNCVEFNPLNKEFISCSDDGSLRLWNLDDHKVITKCINKHRTKGANGKRVSPQVCTFSPDGKWIAAGCDDGSVQAWKYGSQY-----------------------VNVNYLVRKAHNGSITSIAFSPDSKRLLSRGFDDTLKMWSLDNPK---EPLLVKTGLENAFKSTDCGFSPRAEVVFTGTS-SPNKDTPGTLQFFDPMTFDLYKIDYPGISCHRIQWHPRLNQII. 434
60 -51.300[R] KOG1524 WD40 repeat-containing protein CHE-2  ali follow..  7  23.........................................................IGTEAILSAADDHVFLLSQQILNMPETFFPTSLHIFPRSQTKGGQNDVFAVSTSDGKINILS---------RNGKVENMVDAHNGAALCARWNSDGLLSSGEDGFVKMWSR-SGMLRSVLAQFATAVYCVAWDSTSSNKMQVAPIKWKAHDGIILCCDWNPTSDLIVTGGEDLKFKVWDG-FGQILFNSSVHDYPITSISWNTDGTLFAVGSHN-ILRLCD-KSGWSHSLEKMNAGSVMALSWSPDGTQLAVGTAAGLVFHAHIIDKRLTIYIYSSKNWNTPTMIEYNERTVNIIVQCEKIFLVSDGMTITIFTYEGRK----------------------LINLNPPGQVMALLDERKIDLANDTLVVRDRADNKVLHFFDPTTGKAQGDGN-----LKHEHDIVELTVNQCGPLNDR---NVAFRDQIGAVHIAMVKTFGVQRMVKIGSLVEQLVFNDVTNMLC. 520
61 -50.600[A] KOG0284 Polyadenylation factor I complex, subunit PFS2  ali follow..  12  1MNGGMMRGNQMPNVTLTIQPSTSSMQNSQPRIMNNHHHPHNRFQREHVMPDVMGDGPGRRLRKNVANVRRHVDYVSTVLNHCENRLWQYGKQRILQQPDILYQQYAVPADSTP--------DVPVDCILTKFIRTAMNKVKCPVYSVCWSPEGLITGCQTGEFTLWNGTAFNFETIL---------------------------QAHDSAIRALKWASNEQWLLSADQGGYVKYWQPNMNNAHMFSAHKDEAIRGLAFAPTDVKFATASDDGTARVWDFARYTEERVLRGHGAEVRCIDWHPTKGLIATGSRDQPVKIWDPKSGSCL---------ATLQEHKSSVMAVEFNKNGNWLLTGGRDHLVKMYDIRMMKEMRT--------------------------YRAHKKEVISLAWHPIHELFVSGGGDGSIVYWMVDGEKEIGLLEH-----AHDQAIWSMKWHPLGH-------ILATGSNDNNTKFWARNRPGDTNMIGHLDKEREPRMAPPKPSIET 457
62 -50.500[R] KOG2055 WD40 repeat protein  ali follow..  10  28......ENETFDVMMNEAPELSEDNDAQEDELEKLEDAELFMFDTGSADGAKDSVPLDIIAGDNTVKEDEEASNEIPSI------EDSDDERLMISLQDHSRLRKLRQYEDEDMVNGLQ----------------YARRLRTQFERVYPVPEWAKKQDVTEEEDEFNALSEKSVIPKSLKSLFKSSVSYINQSSKLLAPDANFQAPSHSGIRCMSIHPYFPLLLTCGFDRTLRIYQLDVNPLVTSLHLRSSALQTALFHPDGKRVIAAGRRKYMYIWDLESAQVQKVQENFQPSMERFHVDPTGKYIALEGRSGHINLLHALTGQFA----------TSFKIEGVLSDVLFTSDGSEMLVLSYGAEVWHFNVEQRSVVRRWQVQDGVTTHFCLDPSNDAAPKPVTTLDNITFSINSMSFSQDSQVLAIASKKDTLRLVHVPSFSVFRN-----TSATPLGRVTCLAFGKGGE--------LCVGNEAGRVGLWKLAHYDLKFVP--KIINWEIRLGKFGYVLL. 542
63 -50.200[R] KOG1188 WD40 repeat protein  ali follow..  9  34................................................................................................................................................TVQAGKENLVAVLCSNGSIRIYDKERLNVLREF---------------------------SGYPGLLNGVRFANSCDSVYSACTDGTVKCWDARVAKPVQLFKGYPSNFISFDINCNDHIICAGTEDALLVFWDARMNSLGAYSETHSDDVTQVRFHPSNPMVVSGSSDGLVNVFDINIDNE------EDALVTTCNSISSVSCIGWSGKGKQIYCMTHDEGFYWWDLNHLDTDEPVTRLN------------QDVREVVNMKEDALDYLIGGLYHEKTDHVIGGTNKGRIHLMNCSMSGLTHV---TSLQGGHAATVRSFCWNVQDD-------SLLTGGEDAQLLLWKPGAIEKTFTKESMKIASSVHQRVRVHSNDS 380
64 -49.800[A] KOG0272 U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats)  ali follow..  11  1MSDD-LEESERKRQNAAASGAAATTTSGTTASSGAGTTTTGTGGQLEDIDSDEDYEESTKKTSNAKQAGAPPPTAAT-YFDLEMEMERDKVALLEEFERKKRARQINVSTDDTEIKSNLRQLNE--PAERRRRLKELLAGLGENAINKRQYEDRKQQQREQDQATWYHEGPDSLRIARSLPRAKDRLVRAREAKLQSLAPLCSQVGDTRPVSSAAFSEDSSLLLTSSWSGLCKLWSVPDCELKQTLRGHASYVGGVALRPGVKAMASGGHDGAVKLWGFNNEESIADITGHPHRVSKVAFHPSGRFLATACYDSSWRLWDLEQKTEVL---------HQEGHAKPVHCLSYHSDGSVLVTGGLDAFGRVWDLRTGRCIMF--------------------------LEGHLGAVFGVDFSPNGFHIATGSQDNTCKIWDLRRRQPV------YTIPAHTNLISDVKYQQECGS------FLVTCSYDSTTKIWSNKTWQPLKTLGHDNKVISVDIAPNSQYIAT 539
65 -49.700[R] KOG4227 WD40 repeat protein  ali follow..  13  14.....................................................................................................VVGFLSQRGLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGLVSGGDDRRVLLWHMEQAIH----------------------SRVKPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETLDVF-AHEDAVYGLSVSPVNNIFASSSDDGRVLIWDIRESPHGECLANYPSAFHSVMFNPEPRLLATANSKEGVGLWDIRKPQSSLL------RYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFD----------------------NQGYFNSCTMKSCCFAGDRDYILSGSDDFNLYMWRIPADPEA-VNGAFMVLKGHRSIVNQVRFNPHTY-------MICSSGVEKIIKIWSPYKQPGGDLDGRIEDDSRCLYTHEEYIS.. 391
66 -49.400[S] KOG0294 WD40 repeat-containing protein  ali follow..  13  3.....................................................................................................................................................PEMEIIEATNEELLLGFKLIKSPTDGF----------------TDSVKFELKQTFADSSYARSITSLAVQWPWVASGGTDGRIFVYDMRTRKQSQIILSHAGRVNTLKFTPDLSLLLSGSDDGHMIATRVGSWTKEYDWKAHAGAVTHVSCHPSSKLALSLGGDQVLNTWNLVNGCVAHKTN----LKNKATLDFQTGCLSWSKQGDHFTLSG-PLVLEIWGIENAHVMRRIE---------------------------MPSKPICITWLD-GNECLTGLDNGNIAWISLKDE----DDTPPTFILAHEVRVKAIAYLNE---------FLATVSIAGQIKVWKIDMETRKLEEIARSRPTDLGLLDLRQFGNV 321
67 -49.200[R] KOG4497 Uncharacterized conserved protein WDR8, contains WD repeats  ali follow..  11  2....................................................................................NFSEVFKLSSLLCKFSPDGKYLASCVQYR---------LVVRDVNTLQILQLY-TCLDQIQHIEWSADSLCAMYKRGLVQVWSLEQPEWHCKI---------------------------DEGSAGLVASCWSPDGRHILNTTEHLRITVWSLCTKS-VSYIKYPKACLQGITFTRDGRYMALAERRDCVSIFVCSDWQLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLL------STYSAYEWSLGIKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEFKSPQLGLGCLSFPPPRLQTLKPVTDRANPKMGIGMLAFSPDSYFLATRNDNNAVWVWDIQKLR-------LFAVLEQLSPVRAFQWDPQQPR-------LAICTGGSRLYLWSPAGCMSVQVGEGDFAVLSLCWHLSGDSMA. 431
68 -49.000[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  8  350.....................................PEYLFDAKETKEWLKLKDEPHKRKLHFMPQKFKSLREVPAYSRYLRERFLR-----CLDLYLCPRAKRVKLNIDAEYLIPKLPSPRDL-QPFPTVESMVYRGHTDLVRSVSVEPKGLVSGSDDKTVKIWEIATGRCIRTI-ETDEVVRCVAWCPNPKLPKVGDKVLVKKTDDLLAEAPSQDVIESERIKTAVQWSNAEADEQEKGVRVVITHFKPIRQVTWHGRGDYLATVMPEGANRIHQLSKRRSQIPFSKSKGLIQFVLFHPVKPCFFVAT-QHNIRIYDLVKQELV---------KKLLTNSKWISGMSIHPKGDNLLVSTYDKKMLWFDLDL-------------------------STKPYQTMRLHRNAVRSVAFHLRYPLFASGSDDQAVIVSHGMVYNDLLQNPLIVPLKKLQT-VLDVNWHPVQPW-------VFSTGADSTIRLY............................... 783
69 -48.100[R] KOG1273 WD40 repeat protein  ali follow..  9  1........................................................................................................................MNAPIIDPLQGDFPEVIELEHGVIKCVAFNHRGLAAGCADGGCVIWDFETRGIAKEIRDN-------------------------DCSAAITSVSWSKYGHRLLVSAADKSLTLWDVSTGEKIARTINPPFSPAAACFNKCGDLVYIGNSKGEILIVDYKSVRVLALVSSGAAPVKNIVFSRNGQYLLTNSHDRTIRIYENLLPAKNKMKTVGSKCLTLFREFQDSVAPCFSGDGEWVVGGSGEHKIYIWD---------------------------RAGHLVKILEGPKEALIDLAWHPVHPIIVSVSLAGLVYIWAKDYTENWSAFAP-----DFKELEENEEYVEREDE-------FDLIPETEKVKVLDVNEDEEVDIDVEKDAFSDSDMSVEELRYLP 419
70 -47.500[S] KOG0283 WD40 repeat-containing protein  ali follow..  12  209YQTPIRQTPAVCGNGKALRGGGEALTSVMSNARVGAFFLIKNLDTGKEFIVNEYDEDGMWNRLSDLQTGKQLTLVKELMRRENVNRINYEPLMDLRKFNSYLSKSVRLSKRRGAALLKN-------KGVAHSMSLRVADKDVSDGSTDSPKKGHKHGKANEWVKVRPTGKSYK--------------------ELSALHMCQEIQAHEGAVWTIKFSQDAHYLASGGADRVIHVWEVQECELMSMNEGSLTPIHPSLCDSSGNEITVVEKKKKGKGSSGRSDKPVCSLKGHLDAILDLSWSKSQL-LLSSSMDKTVRLWDIETKTCL----------KLFAHNDYVTCIQFSPDENYFLSGSLDAKIRIWSIQDRHVV---------------------------EWSDLHEMVTAACYTPDGQGALIGSHKGICRAYDTEDCKLSQTNVQSNKKSQAKRKITSFQFSPVNPS------EVLVTSADSRIRILDGSEVIKFKGFRNTCSQLSASYSQDGKYII. 698
71 -47.400[T] COG5170 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  10  12...........................................................................................................................KFAQCFGDKGDVEDITEADIISAVEFDHTGLATGDKGGRVVLFERNHSKKGCEYKFFTEFQS----------EPEFDYLKSLEIEEKINKIRWCKRTNHFLLSTNDKTIKLWKLYEKNLKVVANAHAYHINSISVNSDAETYISAD-DLRINLWNLSISDHSENMEELTEVITSAEFHPNCNHLMYSSSKGNIKLLDLRQSALFEDQEDQDSKSFFSEIISSISDVKFSQNGRYILSRD-YLTLKIWDVNMKAPVKTIPLHDVLRSKLCDLYENDCIFD-----------KFECTFSGDDKHVLSGSYSNNFGIYPTDSSLPGDSVGLDPDNLDYNKKILHASWHPFED-------SVAIAATNN-LFVFS.............................. 461
72 -47.200[KL] KOG4283 Transcription-coupled repair protein CSA, contains WD40 domain  ali follow..  13  10........................................................................................................................................................................................................................TGRIRSNSFANRFKSRRILSLQLSNRKDFVSPHRGSVNSLQVDLEGRYLLSGAADGSAAVFDVQRATDKQHENGHKYAISSAIWYPDTGLFITGSFDHYLKVWDTNTAQAVVDF-------KMPGKVYRTAMSSMAMSHTLIAAGTEDVQVRLCDIASGAFSHT--------------------------LSGHRDGVMSVEWSTSSEVLYTGGCDGAIRFWDIRRAGCFRV---------LDQSQTQLGFRPPIL-------KRTAVGSKVC................................... 253
73 -46.900[E] KOG0280 Uncharacterized conserved protein  ali follow..  10  1.........................................................................MSETGIIPKST----YTDWPADVCKYSQVFEDVLVVG-----------TYMLDESTKLRHGKLVLYDTKEDVLSPHDASVLAVAHSTGHVSFYRHQFRAELMFLRGI----------------------KVADSSVLMLSLDFSDSGKELAVSMSNGSVLIIDIDSGVIKNKWKEHDYEAWTCHYSRDNNLLYSGGDDAALVCYDQRIPNWRDIQVHHSGVVSILSRAPFGPYIATGEYGDFMHTLDTRNIGKPL---------FSANLGGGVWRLEHMETTEKVLGILMHRGAQVLRISNDF---------------------SSIDASKRIFKEHESMCYGGDWRHTDGLLATCSYDKRVCLWE..................................................................................... 308
74 -46.700[R] COG2319 FOG: WD40 repeat  ali follow..  9  1MSTLYQVNKIKESSTVYGQNAERSNTPTLIDPSNKETANVCPISKNLFQSYPKGSYRNSQRLTSRNGLDRFITSNKDTISLGRHSSLSRNLVNKTKNASETYQQLLEYALVERDDNVFKKNRSPENLLPFRILDAPELRDDFYTSLLSWSPKGDLAIGLAENIYLWSKELGP----------------------------TRVLEESIYDVSSVAYSYNGDILAVGRVDGTLQFWQDNERV-PRISIHHPGDIGVLAWKPETNRLLVGKGNGNIFVYDIIAVLVATITNAHDEQVCGLTWNHDGSQFASGGNDNRVCLFKGSDLRQP---------LYVWQQNAAVKALSFCPWQRSLLAGSHDKHIRFYNCFNGKKIDELYCG---------------------------AQITSIHWSPKYREFSVTTVQHRFAVYSWPQLECLVS----VLPSVPDIRCVHSVLTSQLNETTGMTDSIIIASSNETIKFFDLSEESSWHNSWHGIFDSQILEMLEG..... 525
75 -46.300[R] KOG2321 WD40 repeat protein  ali follow..  8  1.................................................................................MSLKVQNPNNVRVYTVSGEGVTQRLPNWISKRKLKKDYALSHRIELLQD--------EYPEASNRIKCTRDGMATGVYKPHIKVFDFAEMSLKFERHTDAENVQFEILSDDWTFHSQGGIHYSTRIPKYGRDLKYHYPNCDLYLAAAGDEVYRLNLEQGRFLNPLKSPTGGVNVIDINPMHQLLAFGTDAGSVEFWDPRDRSRVGILSDNSRSVTALKYRNDGLNVAIGLSDGATLLYDLRSSSPYM--------SKDQGYSMPIKSLHWMDDGTARVLSADSKIIKIWEKDTGKPFSSI---------------------------EPTVELNDVCPIEGTGLILTANEGSPMHAFYIPSLNPAPRWCS-----FLDNITEEMEENPAP--TIYDDYKFVTKKELLNLGLDHLVGTGVIRAYMHGFFIDNNLYEKARLIANP 430
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Rychlewski L, Ye Y, Jaroszewski L, Godzik A. Integrated web service for improving alignment quality based on segments comparison. BMC Bioinformatics. 2004 Jul 22;5(1):98.