FFAS03 results for KOG0330

Query: [A] KOG0330 ATP-dependent RNA helicase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.

						. 10 . 20 . 30 . 40 . 50 . 60 . 70 . 80 . 90 . 100 . 110 . 120 . 130 . 140 . 150 . 160 . 170 . 180 . 190 . 200 . 210 . 220 . 230 . 240 . 250 . 260 . 270 . 280 . 290 . 300 . 310 . 320 . 330 . 340 . 350 . 360 . 370 . 380 . 390 . 400 . 410 . 420 . 430 . 440 . 450 . 460 .
#	Score	Template	Links and tools	%id	First	`MAPSEKKLTEDKKNSSLNKKIETSNSSSEKSSENNNGDSQNNEAPKTFKELGVIDELCEACEKLGFKTPTPIQQEAIPVVLNKRDVIGLAQTGSGKTAAFALPVIQELWNNPSPFFAVVLAPTRELAYQISEQFEAIGGSIGVRSVVIVGGMDMVTQAVALSKKPHVLVCTPGRLMDHLENTKGFSLKNLKYLIMDEADRLLDMDFGPIIDKILKIIPHERRTLLFSATMTSKVEKLQRASLHQPVRVAVSSKFSTVDTLIQRYLFFPFKHKDTYLVYLVNELAGNSIIIFARTVNDTQRLAILLRTLGFSAIPLHGQLSQSNRLGALNKFKSGARSTLVATDVAARGLDIPLVDVVINYDIPTDSKAYIHRVGRTARAGRAGKSIALVTQYDLEPFLRIEATIGKKMQEYEIDKEGVFLLSERVGEAQREAIIQMKEIHDRRKSKGKLHTKRKRDDLDREEQIY`	Last
1	-122.000	`[A] KOG0330 ATP-dependent RNA helicase`	`ali`	100	1	`MAPSEKKLTEDKKNSSLNKKIETSNSSSEKSSENNNGDSQNNEAPKTFKELGVIDELCEACEKLGFKTPTPIQQEAIPVVLNKRDVIGLAQTGSGKTAAFALPVIQELWNNPSPFFAVVLAPTRELAYQISEQFEAIGGSIGVRSVVIVGGMDMVTQAVALSKKPHVLVCTPGRLMDHLENTKGFSLKNLKYLIMDEADRLLDMDFGPIIDKILKIIPHERRTLLFSATMTSKVEKLQRASLHQPVRVAVSSKFSTVDTLIQRYLFFPFKHKDTYLVYLVNELAGNSIIIFARTVNDTQRLAILLRTLGFSAIPLHGQLSQSNRLGALNKFKSGARSTLVATDVAARGLDIPLVDVVINYDIPTDSKAYIHRVGRTARAGRAGKSIALVTQYDLEPFLRIEATIGKKMQEYEIDKEGVFLLSERVGEAQREAIIQMKEIHDRRKSKGKLHTKRKRDDLDREEQIY`	465
2	-107.000	`[A] KOG0340 ATP-dependent RNA helicase`	`ali follow..`	40	14	`.IMSKSRKNPKTVVNIQSQKLDSDQNTPQFEKFTNPNPSSDTTSATNFEGLGLAEWAVETCKELGMRKPTPVQTHCVPKILAGRDVLGLAQTGSGKTAAFALPILHRLAEDPYGVFALVVTPTRELAFQLAEQFKALGSCLNLRCSVIVGGMDMLTQTMSLVSRPHIVITTPGRIKVLLENNPPPVFSRTKFLVLDEADRVLDVGFQDELRTIFQCLPKSRQTLLFSATMTSNLQALLEHSSNKAYFYEAYEGLKTVDTLTQQFIFEDKDAKELYLVHILSQKGIRSAMIFVSTCRTCQRLSLMLDELEVENIAMHSLNSQSMRLSALSKFKSGKVPILLATDVASRGLDIPTVDLVINYDIPRDPRDYVHRVGRTARAGRGGLAVSIITETDVKLIHKIEEEVGKKMEPYNKKVITDSLEVTKVSKAKRVAMMKMLDNGFEDKVKDRRKLKRKTLADKGLLK..`	480
3	-106.000	`[A] KOG0326 ATP-dependent RNA helicase`	`ali follow..`	27	41	`.NNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKG-VAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEE-LTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIP.....................................................`	450
4	-102.000	`[J] KOG0328 Predicted ATP-dependent RNA helicase FAL1, involved in rRNA maturation, DEAD-box superfamily`	`ali follow..`	29	1	`....................MARKNAQAEDLSNVEFETSEDVEVIPTFNAMNLKEELLRGIYAYGFEKPSAIQQRSITPIVKGRDVIAQAQSGTGKTATFSISILQSLDTTLRETQVLCLSPTRELAVQIQKVILALGDMMNVQCHVCIGGTNLGEDIRKLDYGQHIVSGTPGRVFDMIKRR-VLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTSKFMTDPIRILVKRDELTLEGIKQFFVAVEEEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVWARGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKSDDIRILRDIEQYYSTQIDEMPMNVADLI..............................................`	399
5	-101.000	`[J] KOG0327 Translation initiation factor 4F, helicase subunit (eIF-4A) and related helicases`	`ali follow..`	31	2	`...............SASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMAPHIIVGTPGRVFDMLNRR-YLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI..............................................`	406
6	-99.400	`[A] KOG0329 ATP-dependent RNA helicase`	`ali follow..`	30	2	`..AENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMNVKVAVFFGGLSIKKDEEVLKKNPHIVVGTPGRILALARNK-SLNLKHIKHFILDECDKMLELDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEDAKILNDVQDRFEVNISELP.....................................................`	415
7	-99.100	`[LKJ] COG0513 Superfamily II DNA and RNA helicases`	`ali follow..`	37	2	`.............................................TTFAELGLSPKVIAAVEAAGYTAPTPIQAGAIPPALERKDVLGIAQTGTGKTASFVLPMLTLLEKGRRMPRTLILEPTRELAAQVEENFVKYGINHRLNVALLIGGVSFEEQERKLERGADVLIATPGRMLDHFERG-KLLLTGVEILVIDEADRMLDMGFIPDIERICKLIPFTRQTLFFSATMPPEITKLTEQFLHSPVRIEVAKASSTAKTVTQRLVKSGKKDKRAVLRDLIQSEGDKNAIIFCNRKKDVSELFRSLTRHEFDAGALHGDMDQRARMAMLSSFKDGKLRLLVASDVAARGLDIPDVSHVFNFDVPIHAEDYVHRIGRTGRAGRSGKAFTIVTSSDTKYLAAIESMIGEKIEWHDGDLSTLAVSEEADEQPRKGRNARGKGKEKPKEKASKPVAAKTVDPAGQPQ...`	424
8	-94.600	`[A] KOG0332 ATP-dependent RNA helicase`	`ali follow..`	26	165	`.AHEQVPVPADIALLNKFIQKEVKMMKDVVVDVQRQDPKSPLYSISSFRELRLKPEVLKALDTMNFQFPTRIQETALPLLLPPSNLIAQAQSGTGKTAAFVLTMLCRIDVNLMCPQCICLAPTLELAKQIGEVVEKMGKFIDNLKIHYAIKGGNMAAMRGRKLTEQIVIGTPGITRDYLQKYKCIDPSKIRCLVLDEADVMIYHQGFTDIYNMVEDASDSVQSMLFSATYDEPVINFATKIIKNAIVVMLKREEQALPNIKQFYVQCACRDKYAAIVNLYSGLAVASSVIFCHTKASVMWLYENMRARGHQVDVLHGDMTVVERADTIIHFKRGDFKVLITTNVFARGIDVAQVSVVINYDLPPDCETYLHRIGRTGRFGKTGIAINLIDSEDMNMINVLENHFQMKIARMDPSNLVELEAIEMA........................................`	613
9	-93.400	`[A] KOG0350 DEAD-box ATP-dependent RNA helicase`	`ali follow..`	29	82	`.PHDLLPIPQPSVEDFVDSKPHVKNITSVLPKWLAEPITVDPNTTVEFSSLNISSKLVERLQKQNITRGFAVQAAVLPLLLQGGDVCVSAATGSGKTLSYVIPIVQCLSHRTPRLRCVVIVPTRELTVQVAKTFEYYMSGAGLQVCAWTGQKSLRHETYQLNGDIDVLVSTPGRLVDHIRNDESFSLQHLRYMVIDEADRLLDQSFQDWVDTVMMEIPSPLQKLVFSATLTRDPSKIASLKLHNPRLVLVQNKDMEVDDGGEEYHVSVSSEKPILLYHLIHSKNLTNILCFVKSNEAAARLHRLLENQSFSCGLFTSSLSRDERKKIISRFATGDLNLLVCSDLMARGIDVANTQNVINYDPPLSVRSYVHRIGRTARAGREGFAWTLVQSHEGHHFSKLVKQLRRTLPIKRIKIEFSHISEEFVVAYDKALEALRVEVFNSRYPQQK.................`	600
10	-92.100	`[A] KOG0344 ATP-dependent RNA helicase`	`ali follow..`	27	8	`IEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPAKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFPKSSKKFDILVTTPNRLIYLLKQDPPIDLASVEWLVVDESDKLFETGFRDQLASIFLACSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQNSKKK...`	484
11	-90.500	`[A] KOG0342 ATP-dependent RNA helicase pitchoune`	`ali follow..`	33	45	`.QEEENEDADQNTSVESESEELDNENEDERVQKSVNLNASSTSDIEKFSDLQLSENIQKAIKEMGFETMTEIQKRSIPPLLAGRDVLGAAKTGSGKTLAFLIPTIEMLYALKNGTGVIIISPTRELALQIFGVAKELLKYHHQTFGIVIGGANRRAEADKLVKGVNLLVATPGRLLDHLQNTKGFVFRNLRSLVIDEADRILEIGFEDEMRQIMKILPENRQTLLFSATQTTKVEDLARISLKGPLYVNVGKPTSTVEGLEQGYVVVDSDKRFLLLFSFLKRNLKKKVIVFMSSCASVKYMAELLNYIDLPVLDLHGKQKQQRRTNTFFEFCNAEKGILLCTNVAARGLDIPAVDWIVQYDPPDDPRDYIHRVGRTARGTKTGKSLMFLAPSELGFLRYLKT-AKVSLNEFEFPANKVANVQSQLE.......................................`	477
12	-89.700	`[A] KOG0348 ATP-dependent RNA helicase`	`ali follow..`	29	2	`..................KRAQQSARETKQEAKDASKAKSGLFASCSFSSLGLDTKLSDQLKEMGFEAPTLVQAQAIPVILSGRDVLVNAPTGTGKTIAYLAPLIHHLQGRSHGTFALVIVPTRELCLQVYETLEKLLHRFHIVPGYVMGGEKKAKEKARLRKGISILIATPGRLLDHLKNTASFVHKNLRWVIFDEADSILELGYGKEIEQIIKLLGSQKQNLLLSATLNDKVNDLAKLSLDDPVMIGLDNTKGIPSQLVQRYLRVPCGARLVALLSVLEREASQKVVVFFSTRDAVDFHYSLLSEFKCKTFRLHGSMEQEDRRSAFGTFKTEKQAVLLSTDVAARGLDFPKVRCIIQYDCPGEATEYVHRVGRTARIGEKGEALLFLQPIEIDYLKELKKHGASLTEYPLMKVLDKFPIPGNMPRIKKVLSLESHPWVISLQRALESLTYAEPKMKSLAKNAF`	529
13	-81.700	`[A] KOG0345 ATP-dependent RNA helicase`	`ali follow..`	33	2	`.................................DSSANINKALTETRFSDLELSGDIIEALNQSDFEFCTPVQAATIPLLCSYKDVAVDAATGSGKTLAFVVPLVEILRRKPHQVMGVIISPTRELSTQIYNVAQPFVSTLNVNSVLLVGGREVKADMKIIEEGCNVLIGTPGRLSDIMERMEILDFRNLEILILDEADRLLEMGFQRQVNYIISRLPKQRRTGLFSATQTEGVEELAKAGLRNPVRVEVRAKSKTPSGLHLEYMECEADKKSSQLVDLLIKNSDKKLIVFFMTCASVDYWGLVLSKKSISLIPIHGDMKQNARDKALASFTKASSGALLCTDVAARGLDIPGIDYVVQYDPPQDPNMFNHRAGRTARLGRQGRAIVFLLPKEEAYVEFMRIR-RVPLEERKCSEDASDVIPIIRSAAMKDRAVMEKGLK.........................`	432
14	-81.200	`[A] KOG0346 RNA helicase`	`ali follow..`	26	2	`.................................EKSGGIREESSEKTFSDFNLDPRLQRAIHKCEFEKPTSVQSETIPLALEGKDLVAQARTGSGKTAAYLIPILELLDENQRGIFALLLVPTRELAQQVYNVLEKLTAFCSIRFINVATNSSDTVQRPLLLDLPDIVIATPSRCVVHVASG-VLPLDKLKFLVIDEADLMLSFGYNEDMKTLSRSLPRGTQSFLMSATLSKNIASLQKLVCRNPFILAVKDK-EASGKLTQYVVKCSEQDKFLLAYILLKLRLIKKILIFVNEINRCYRLKLFLEQFGLKSLVLNSELPVNSRLHILEQYNKGLYQIIIATDESGRGLDFENVACVLNFDMPSNTKSYIHRIGRTARAGKPGTAMSFVVPKSEVGKHKPTSLESCKKDESVLRRLEKKQISLQPYSFDKNQIDAFRYRMEDALRAVTTVAVSAARAAELKQEL.`	505
15	-80.200	`[A] KOG0347 RNA helicase`	`ali follow..`	26	147	`.EKKKKKQKKINEAAKNQDASAAVSCDGDDTVEEQVEEEEIPPEFSAWSSMRLHPLLMKSIYRLDFKEPTKIQKACFNAAYQGKDVIGAAETGSGKTLAFGLPILQRLLDERGYLRALIITPTRELALQVTEHLENAAKNLSVKVVPIVGGMFSEKQERRLKEKPEIVVATPGRLWELMSAGELVELHSLSFFVLDEADRMVERGHFRELQSILDLLPKKRQTFVFSATIALSSDSERAGMRDNVAIIDLTTTSILAPKIEESFIKCEEKEKDAYLYYILSVHGQGRTIVFCTSVTDLRHISGLLKILGLDVCTLFSEMKQRARLKSIDRFRASENGILIATDLVARGIDIKNVRTIIHYKLPHSAEVYVHRCGRTARAFADGCSIALIEPNETSKFYTLCKSFSMESVKIFPLDNSYMPAVRKRLYLARQIYEIERKGSRENADRTWLKKHAESMELELDDE..`	681
16	-78.600	`[A] KOG0341 DEAD-box protein abstrakt`	`ali follow..`	32	112	`...........KPPLHIRKMSSKQRDLIRKQWHIIVNGDDIPPPIKNFKDMKFPRPVLDTLKEKGIVQPTPIQVQGLPVILAGRDMIGIAFTGSGKTLVFVLPMIMIALQEEEGPIGLIVCPSRELARQTYEVVEQFVAPLPLRSLLCIGGIDMRSQLEVVKRGVHIVVATPGRLKDMLAK-KKMSLDACRYLTLDEADRLVDLGFEDDIREVFDHFKSQRQTLLFSATMPTKIQIFARSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTS-PPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDREYAISSFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPAEIENYVHRIGRTGRCGKTGIATTFINKNQKHLLQEAKQRIPPVLAEL......................................................`	531
17	-76.900	`[A] KOG0331 ATP-dependent RNA helicase`	`ali follow..`	30	61	`............EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGK-TNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSAHNILQIVDVCHDVEKDEKLIRLMEEEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYS..`	519
18	-76.800	`[A] KOG0338 ATP-dependent RNA helicase`	`ali follow..`	33	174	`.DYSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGK..`	641
19	-76.000	`[A] KOG0349 Putative DEAD-box RNA helicase DDX1`	`ali follow..`	34	2	`.............................................AAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQIVYETLKAPKALIVEPSRELAEQTLNNIKQFKKYIKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGK-LNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQRLQVIVCSATLHSDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKE..................................................`	645
20	-75.300	`[A] KOG0336 ATP-dependent RNA helicase`	`ali follow..`	30	181	`.....ESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCRFKDAFQQPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPNGPGMLVLTPTRELALHVEAECSKYSY-KGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMNNS-VNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVANTVKQNIIVTTEKEKRALTQEFVENSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRA..........................................................`	589
21	-69.500	`[A] KOG0343 RNA Helicase`	`ali follow..`	32	2	`......AKKNRLNTTQRKTLRQKEDEYIENLKTKIDEYDPKITKAKFFKDLPISDPTLKGLRESSFIKLTEIQADSIPVSLQGHDVLAAAKTGSGKTLAFLVPVIEKLYREKDGLGALIISPTRELAMQIYEVLTKIGSHTSFSAGLVIGGKDVKFELERI-SRINILIGTPGRILQHLDQAVGLNTSNLQMLVLDEADRCLDMGFKKTLDAIVSTLSPSRQTLLFSATQSQSVADLARLSLTDYKTVGTNKEASTPETLQQFYIEVPLADKLDILFSFIKSHLKCKMIVFLSSSKQVHFVYETFRKMGISLMHLHGRQKQRARTETLDKFNRAQQVCLFATDVVARGIDFPAVDWVVQVDCPEDVDTYIHRVGRCARYGKKGKSLIMLTPQEQEAFLKRLNARKIEPGKLNIKQSKKKSIKPQLQ.......................................`	434
22	-68.800	`[A] KOG0333 U5 snRNP-like RNA helicase subunit`	`ali follow..`	36	268	`............RMKELSEMSDRDWRIFREDFNISIKGGRVPRPLRNWEEAGFPDEVYQAVKEIGYLEPTPIQRQAIPIGLQNRDVIGVAETGSGKTAAFLLPLLVWITSLPLGPYAIIMAPTRELAQQIEEETNKFGKLLGIKTVSVIGGASREDQGMKLRMGVEVVIATPGRLLDVLEN-RYLLLNQCTYVILDEADRMLDMGFEPDVQKVLEYMPKYRQTVMFTATMSSAIERLARQYLRRPAVVHIGSAGKPTERVEQVVYMVPEDRKRKKLVEVLESQFQPPIIIFVNQKKGADMLSKGLTKLGFKPTVLHGGKGQDQREYALQALKEGTSDILVATDVAGRGIDVKDVSLVLNYDMAKSIEDYTHRIGRTGRAGKHGKAITFLTPDDTAVYFDLKQVLVES..........................................................`	695
23	-67.300	`[A] KOG0335 ATP-dependent RNA helicase`	`ali follow..`	29	253	`..........EDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPEMKKLISCSKEQRQTLMFSATFPEEIQRLAAEFLKNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSTLNTAGFSSSQAPNPVDDES......`	722
24	-65.800	`[A] KOG0337 ATP-dependent RNA helicase`	`ali follow..`	28	51	`.DLDFGEDRKKQADEIPGFPSLDNDAGTSDRGADILKSKSKKNKSGGFQSMGLGFELIKGITKRGYKVPTPIQRKTIPLILEGRDVVAMAKTGSGKTACFLIPLFEKLQRREKGARALILSPTRELAVQTYKFIKELGRFMELKSILVLGGDSMDSQFSAIHTCPDVIVATPGRFLHLCVEM-DLKLNSIEYVVFDEADRLFEMGFGEQLNETLHRLPSSRQTVMFSATLPKLLVEFARAGLNDPVLIRLDVESKLPDALALKFLYCRPDDRYTALVVLLKYPVQSQTVVFAGTQHHVELISYILTEAGISNASVYSSLDPAARKINTAKFVNKKVSVLIVTDVAARGIDIPSLDFVVNLHFPGKPKLFVHRVGRCARAGRTGTAYSIVSTDDTAHLLDLHLFLNRPFNIHDSSALGTIPQDLLEEEHLTVTDIKKSHH..........................`	491
25	-59.100	`[A] KOG0339 ATP-dependent RNA helicase`	`ali follow..`	31	232	`............EHEDIKRLHYMDVIRLQNTMNLRVGGLKPPRPVCSFAHFSFDKLLMEAIRKSEYEQPTPIQAMAIPSALSGRDVLGIAKTGSGKTAAYLWPAIVHIMDQPEGPVAVIVVPTRELAIQVFQEAKKFCKVYNINPICAYGGGSKWEQSNELQEGAEMVVCTPGRIIDLVKM-GATNFLRTTFLVFDEADRMFDMGFEAQVKSISDHVRPDRQCLMFSATFKQKVERLARDALVDPVRIVQGEVGEANADIEQKVFVMQNDVKLHWLIRNLVEASLGKVLIFVTKKLDSEDVAKKLKMKDFDIVLLHGDMLQAERNENLLKFRKK-SQILVATDVAARGLDISEIRTVINFDMARDIDTHVHRIGRTGRAGHKGTAYTLVTEKDIEMVGHLVKNLESV..........................................................`	632
26	-55.900	`[S] KOG2340 Uncharacterized conserved protein`	`ali follow..`	16	118	`.IKNSIAAYDEGKLCKSIEESKLGVSQSFFPDVTKRLPCSCLSEIKNIDDLGLKQRILDSYKKQKPSGQTSMQIELAKAMFNYQDVFFTNMSHKLGTSLLALHALNHVFKTRDRVKVLILLPTRNSAFEFINLLISYSGTNQVEFRYLFSGNTDDMFRLGVKYNSDIIVASPLGLRLAIGNKGDKKLSSIEIAMVDQAHALVMQNWIECIFDELNGLPKERQTILFSQYNNLDINSFFSHYMSNIASLLHGVLNRLGYKVTQTFVRISVDSIIKSILVQLKKYSQSGILVYIPSYFDFVRVRNYMDEEGINYSAISEYSSVSDMTRARNLFYQGRTNIMLYTERAFRRFDFRGVKAVVMYGPPTNPQFYVELVRMPMRTISEGNLDSDAAKCRIMYTKCLEGIVGYQRVSNMCHGKHEV..............................................`	648
27	-40.000	`[R] COG1201 Lhr-like helicases`	`ali follow..`	23	10	`....................................................FHPKIQEALRTLGFTRPTEPQERAFPHILDGKHTLLIAPTGSGKTESAVLPVFNAILKKKSGISALYITPLRALNRDMLSRIEVMGKLLDIKVQVRHGDTPQSERQRQSRNPPDLLITTPETLQAMFSGSRLRKMETVTHVVVDEIHELASSKRGAQLAIGLERLVEEFQRIGLSATVGNALLKLLEFDVISPQVSGEAEDREVMEIARTVGCEPEFASHLSLIRKIVEES--QSTLIFVNTRQSAEALAAGFRKLGASIGVHHGSLSFEARVEAEEAFKAGALRGLICTSSMELGIDIGNVDRVVQYGSPRQVSRLLQRVGRAGHRLHEVSRGTVLSMEADDTAESTKAALEGRVEDISPHV..................................................`	401
28	-34.500	`[L] COG1111 ERCC4-like helicases`	`ali follow..`	19	16	`...................................................................EARTYQQLLAADVIRKGNSMIVAPTALGKTVVAVLVAAERLRKYRGS-KVLILSPSKPLAIQ---HEESFREFMLATCTSLTGSIKPEERKERWIKS-QIISATPQTVESDILAG-RYDLRDVSLIVFDECHRAVGSYSYVFLASNYIQNARHPLILGLTAS-EDKIKTVCENLFMNEVVVKTEGDPDVRPYLKPIKIEW-EHPKLDRLMEILKREDEARIIVFTQFRDTLEEIYQRCKREGINAVKFYGQLTQKQQRDIIKSFRMGNHDVLLSTSVAEEGIDIPSVDLVVMYEPVPSEIRMIQRRGRTGRK-RKGRMVVLITEKTRDESIRKERSMKENLRGGS.....................................................`	502
29	-33.300	`[L] COG0514 Superfamily II DNA helicase`	`ali follow..`	19	2	`.................................TLTLHSIDMTATLMAESSALFATPERVLHEVGYQQFRVGQQEVIEAALAGRDSLVIMPTGGGKSLCYQIPALVL---------TLVISPLISL---MKDQVDQL-KANGVAAECVNSTLAREELIAIYNRQLKLLYVSPERVLT--EFIERLSHLPLAMIAVDEAHCISQWGFRPEYASLLKQRFPNVPVMALTATADDATRHMQRLQLNEPHQYL-----GSFDRPNIRYMLVEKHKPVSQVIRYLETQRGQCGIIYCGSRKKVEMLTEKLCGNHIRAASYHAGMDADERAWVQEAFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMMLYDPADMNWLRRM.................................................................`	363
30	-33.200	`[R] COG1202 Superfamily II helicase, archaea-specific`	`ali follow..`	18	172	`.......................PTEHPEVTKWDELKAKHVRVERMKVDEVDIPESFKNVLKLEGITELLPVQVLAIKNGLKGENLLVVSATASGKTLIGELAGIPKALEGKK---MLFLVPLVALANQKYEDFKRRYSKLGLKVAIRVGMSRIKTREEPVVIDADIIVGTYEGVDYLLRSGK--KIGNVGTVVIDEIHMIDDEERGPRLDGLIARL-PKAQFIGLSATVGN-PQELAR----RPVDLE---RHLIIARNESEKWRIIAKLCKAEVMRKSSKGFKGQTIVFTYSRKRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIFEGNKWLSVREFHQMLGRAGRPLEKGKVYLIVEPGKKYSAQMDET...............................................................`	562
31	-31.300	`[R] KOG0354 DEAD-box like helicase`	`ali follow..`	19	7	`..SSDEDWDELDTQVVDKIENEYHNNTIGLNGYSVDEYFDANDSNRYRLQHELDESAAQQWVYPINVSFRDYQFNIVQKALF-ENVLVALPTGLGKTF-IAAVVMMNYLRWFPKSYIVFMAPTKPLVTQQMEACYKITGIPKSQTAELSGHVPVTTRNQYYQSR-NVFFVTPQTILNDIKHG-ICDRTRISCLVIDEAHRSTNYAYVEVVHLLSLSNKNFR-ILALSAT-LEAIQNVIDSLHISRIEIRTENSIDISQYVQKKEVDF-GHPKLEHLERIVEQTKDTRIMIFVEIRSSAEEILRFLGKFGQSAVRKAAGMSQKLQNETVKQFQKGEVNTLIATSIGEEGLDIGEVDMIICYDASASPIRMLQRMGRTGRK-RKGYIYMLLTRGKEEAKWERAKDAYRTLQD.......................................................`	566
32	-27.400	`[R] COG1203 Predicted helicases`	`ali follow..`	19	2	`........................................................VIKAFRKLTGHSPYEYQKEAMDNLLEGKSLIIRAPTGAGKTEASLIPFIYGLNDYLPP-QLIYSLPTRTLVESIGERAIKYASFKKLRVAIHHGKKATSSLFEE-----DIIVTTIDQTAGAYKRWGNIFVGGIALTVFDEV-HTLDPEKGLQTAAAIAMQSAK-PSIIMSATLPDVFIERVKERIEKNEIMDVKNESEIKSRRNRKVELINRPDEMLTADTVLKEENCRKLVVVVNTVERAQNLYLDLRKKDYPIFLLHSRYLEKDRAEKEKSFEKKGECIFISTQVIEVGMDIS-SPIILSEVAP---DALIQRAGRCARWGGNGEFHVFGLARD........................................................................`	352
33	-27.300	`[KL] COG1061 DNA or RNA helicases of superfamily II`	`ali follow..`	19	78	`...................................................................EPYPHQSEALAAWKLAGR-VVVLPTAAGKT------YLAQLAMQATPRTTLIVVPTLDLMHQWYAHLVAAFPDAEV----LLGGGS--------RDKSPVLVAT----YDSAAIHAEALGNQYALIVFDECHHLPTDFSKVIAEYALSATPERTDQEVYRKRAEDLAGKALAEHEIVQIKVKLSQRRAMLAHREAKEIALGTDSKLRILANLLAKHYPERVLIFTADNATVYKISQDL-----LIPAITHQTPVKERHEILTKFREGEYNTLVASHVLNEGVDVPAAAIAIILSGTGSTREYIQRLGRILRKGNIQNKQAIL............................................................................`	435
34	-23.800	`[R] COG1204 Superfamily II helicase`	`ali follow..`	19	1361	`................................................................NFKFFNKIQTQVFNSVYTNDSVFIGAPNGSGKTVCAELALLHHWSQEDY-GTAVYIAPIQEIVDRRYEEWYGKFSDLGDGKVLLTGERSQDLKL----QVADLIFCTPSQ--DSLSKRSMRSIQKVDFYICDEL-QLLGGFYGPLYEIVISRIEKNIRVVGLSVSVAN-ARDLGEWLGTSPQCIFNFSPKDRPNPLTIHLQSFSITHFPSLMLAMSKPSQRKSTIVFTPDRKVAKQLAFDLVTFSMADEDESEITSSNDQNIVQYLYRHGLIKVLIASRDVIYSLKAKSNAVIVMYDIDYPISELLQMLGFTASISELSQVILMTVTTKKEYYKKMESHLQVWLHD.......................................................`	1769
35	-23.700	`[L] COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)`	`ali follow..`	16	96	`.....................................................................TPFQEKVSEGLLQQKPTLVHAVTGAGKTEMIYQVVAKVINAGG---AVCLASPRIDVCLELYKRLQ---QDFSCGIALLHGESEPYFRT-------PLVVATTHQLLKFYQA--------FDLLIVDEVDAFPYVDNPMLYHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIWLSDFNRYLDKNRLSPKLKSYIEKKTAYPLLIFASEIKKGEQLAEILQEQNEKIGFVSS--VTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDFVVEANHRLFTKSSLIQIGRVGRSMDRPTGDLLFNASIKKAIKEIQMM..............................................................`	426
36	-22.100	[KL] KOG1123 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, 3`-5` helicase subunit SSL2	`ali follow..`	17	331	`...................................................................VLRPYQEKSLRKMFGNGR-VIVLPCGAGKS------LVGVTACCTVRKRALVLCNSGVSVEQWKQQFKMWSTADDSMICRFTSEA------KDKPMGCGILVTTYSMITHTQKRSRWLQEQEWGIMVLDEVHTIPAKMFRRVLTIV-----QSHCKLGLTATLLREIARVQCAEVWCPMSPEFYREYLTTKTSKKMLLYVMNPSKFRSCQFLIKEQRGDKTIVFSDNVFALKHYAIKM-----NKPFIYGPTSQNERIQILQNFKNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRQEAQRLGRILRAKKGAIAEEYNA...........................................................................`	673
37	-21.300	`[LK] COG1200 RecG-like helicase`	`ali follow..`	16	270	`.....................................................................TNAQKRVVSDIE--QDLLVQGDVGSGKTLVAALAALTAID---NGKQVALMAPTEILAEQHANNFRRWFKPFGIEVGWLAGKVKGKSRQAELEKAVQMVVGTHALFQE------EVEFSDLALVIIDEQHRFLAMTVYADLDSIIDELPPGRTPITTVVVSEERRAEIVMRVKNA---------------------CVNEKRQAYWVCTLIDESEVLEA-------QAAEAIWEDLTKAMLNIGLVHGRMKPQEKQDVMMRFKNAELDLLVATTVIEVGVDVPNASLMIIENAERLGLSQLHQLGRVGRGCTASFCVLMYKPPLGKVSQKRLQVLRDSQDGFVISEKD................................................`	626
38	-20.200	`[R] KOG3089 Predicted DEAD-box-containing helicase`	`ali follow..`	10	54	`.KEERNSEDDSNRPISKRQKKLQKKSKLIEKKKEESQYIVSQRKALPASSPEKIIEYLTTLIREKNPDLSVLELEEL--YFKRNDFLSTEKFDAERRLSNFPAFIQKFSVAP---KKIVFSMSNIRVADVYRSLNGGKNCVKLDDIATVERLLTDSSKKSNKNDSLYFIATPTRMQKIIEATDLFQGKEKLDIILDASYLILSFEAAVLCQVLKTFLNKKSKILLY...............................................................................................................................................................................................................................................`	291
39	-19.800	`[V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases`	`ali follow..`	16	462	`...................................................................GLRYYQEDAVRAVEKAEILLAMA-TGTGKTRT-AIAMMFRLIQSQRFKRILFLVDRRSLGEQALGAFEDTRINGDTFNSIF--------TDKFPEDSTKIHVATVQSLVKRTLQSEPMPVARYDCIVVDEAHRILD--HFDAVKIALTATPALHTVQIFGETYRTAVIDGFLIDQDPPIQIITDDQDFEVADFNRGLVIPAFNRA-NELTNYLDPTGSQKTLVFCVTNAHADMVVEELRAAFIIKITGDADKDARKVQTMITRFNKERPNIVVTVDLLTTGVDIPSICNIVFLRKVRSRILYEQMKGRATRVNKTSFKI...............................................................................`	859
40	-19.400	`[A] KOG0925 mRNA splicing factor ATP-dependent RNA helicase`	`ali follow..`	16	1	`MEPAQKKLRQESKNPYLAHLNNGDDSEEVVSSKGLTRRATTVAQAAKAEEFNDKPFSQNYFKILETRRELPVREEFLKIYHENQIIVFVGETGSGKTTQIPQFVLYDELPHLTNTQIACTQPRRVAAMSVAKRV---ADEMDVDLGEEVG--------DCSGPNTLLKYMTDGMLLREAMTDH--MLSRYSCIILDEAERTLATDILMGLMKRLATRRPDLKIIVMSATL--DAKKFQKYFFDAPL-LAVPGRTYPVEIYYTQEPERDYLEAARTVLQIHVEEGPGDILVFLTGEEEIEDACRKITLEPLKVYPLYGSLPPNQQQRIFEPTPEDTKKVVISTNIAETSLTIDGIVYVVDPGFSKQ-KIYNPRIRRAGRAGRTRPGKCFRLYTEEAFRKELIEQTYPEILRSNLSS..................................................`	446
41	-18.900	`[A] KOG0922 DEAH-box RNA helicase`	`ali follow..`	17	27	`..........................................................MRQKIAEHRRSLPIEKRLVEEVQKNDILIIVGETGSGKTTQ--LPFLYNAGFCREGKMIGITQPRRIAAVTVAKRV---AEECEVQLGQKVG--------DTTSGSTRLKYMTDGLLLREALLDP--HLSRYSVIIVDEADRSVHTDVLLALLKKIQRTRSQPVSEKTEFGNVAS-LKGYQGRKLSPLKLIIMSASLDARVVDILYTVHPESDYVDATLVTIFQEKPGDILVFLTGQDEIESVERLVQERKLLPLAIFSALPSEQQMKVFAPAPTGFRKVILATNIAETSITIPGIRYVIDPGFPASKAQTLQRSGRAGREG-PGKSFRLYPERE---FEKLEDSTKPEIKRCNLSN..................................................`	437
42	-18.700	`[L] COG1110 Reverse gyrase`	`ali follow..`	18	71	`......................................................SEVEDLFKRATGFRFWSAQRTWVKRILRGKSFSIIAPTGMGKS---TFGAFISIYFAIKGKRSYIVVPTTPLVVQTVKKIQDMMERAGVNVRLVYGNLKKKEKEEALKR--DILVTSSQFLATRFDE---LRDKRFDLIFVDDVDAFLKLGFTQEINRAWEVIKLKKQLIVASATGSARGDRI--KLYRELLGFEVGSGRSVLRNIVDTYIIPERSIEEEVENLL--RKLGKGGLIFVPIIEFAEELTNYLKSKGFKVELV-----SAKNKRGLELFERGEVDYLVGVGTIVRGLDLPHIRFAVFAGVPKDVRTYIQASGRTSRAGGITKGLSVIIVDDQKVFNGLIRQMRWRFVEFEIKKFEEINLESVLREIDEDRKKVRLVIEGKISEQVKDLVKSA...........`	640
43	-16.800	`[L] COG4581 Superfamily II RNA helicase`	`ali follow..`	17	215	`.EHLKNVNSKHSEIDDLLPDKRSIVSLPPSTLNLHKQPDYAHVVDSSAPIENFQQLVPEMALDFPFE--DNFQKEAIYHLEMGDSVFVAAHTSAGKTAEYAIALAQK-----HMTKAIYTSPIKALSNQKFRDFKHKFEDVGI----LTGDVQVNPE-------GSCLLMTTEILRSMLYRGADL-IRDVEFVIFDEVHYVNDLERGVVWEEVIIMLPPHVTLILLSATVPKNIYVISTLKRPVPLEHYLWVKQNMFKIVDQHGRFLMDGYKSANLIGHLHKQNLLPVIVFVFSKKRCEEYVDTLTNRDLNNHQ-HGGLLPIIKEIVEILFQRGLVKVLFATETFAMGVNMPAKSVVFSHD---LPGEYTQCSGRAGRRGVTGTVIILSRSEDTASLRHMIMGPSSKLIS.......................................................`	726
44	-16.700	`[S] COG3421 Uncharacterized protein conserved in bacteria`	`ali follow..`	12	59	`........................................................................QKSALENFVIFDRLFNMA-TGAGKTMMMAALILYYFEKGYRHF--LFFVNQNNIVDKTENNFIDPAHAKFLFTEKIL--IRKVEMFSPHSDGIEIKFTSIQKLYNDIHTERENQTKLNLVMLGDEAHHL-RKGWEHMVLELLLNKNGNPGQNVFTATLPEN-EFLQKGYTKEPVMLFRSKTIDESKADYSAFLNWAENVQADDFEFL-KTRTEQALKFMQDNKFGFAHLANWVKQNYQKHNVIITEKTDSETEKLLNNLEANPIRAIFTVDRLTEGWDVLNLFDIVRLYEGQNGGGSNKKSGKTAAAGRGVRYFPFAFEGKQPNKRKFDNDMQHELRI--LEELFYYTHDEQSRYISELKNELRKDGYLPEKDDDKVLATFKLKSEFADNKDF`	593
45	-16.100	`[R] COG4889 Predicted helicase`	`ali follow..`	18	120	`............STTDKWSSNAEKMLENQTIPTNRIGLSAIAESPIDWDIAYPGSELTINLQLKEPYSPRPHQQTAIEKAIEGRGKLIMA-CGTGKTFT-ALRLSEEVARLNNKARILFLVPSISLLSQTLKEWTAQKT-MDLRPVAVCSDSKVSKAAEDIAAGLTVVFST--QSLPAVHAAQEAGAEPFDLVICDEAHRTTGITLAGEDPSNFTRIHDAAKRLYMTAT-SAEVSSMDDEAIYGPEFHRLGFGEAVEKGLLTDYKVVSGKEQDTKTGFSSSDAAMERAVAFARDIKTSQQIAESFPRV-VACQHVDGSMNALERNSRLTWLKAMETKILTNARCLSEGVDVPALDSVIFFNPRNSMVDVVQSVGRVMRKSPGKNYGYIILP..........................................................................`	612
46	-15.400	`[A] KOG0953 Mitochondrial RNA helicase SUV3, DEAD-box superfamily`	`ali follow..`	14	137	`................................................................................HAKTVFPHLDCMDDLKK------DLRQPANWYSN--ARAITRKILLATEVYNKANERGTPCDL----VTGEERKFGISE--SLPANHVACT----VEMTSVNT-----PYEVAVIDEIQQIRDPQRGWAWTRAFLGLIADEVHVCGEPGALDLLQKICET-TGETVEVRLYDRLTELTVENTALGSLDNIVPGDCI------------VCF--SKHDIYTVSREIEARGKEVAVIYGGLPPGTKLAQAAKFNANSCKVMVATDAIGMGLNLS-IRRIIKPSMNERGEREIDTIGRAGRFRTQWEYVTAFKSEDLQTLQRILARTPEPIKQAGL....................................................`	450
47	-15.200	`[A] KOG0923 mRNA splicing factor ATP-dependent RNA helicase`	`ali follow..`	18	241	`..........................................................KRLTLDETRRSLPVKEDLIAAVKEHQVLIIEGETGSGKTTQ--VPYLVEAGFTKDKKMIGCTQPRRVAAMSVAARV---AEEMGVKLGNEVG--------DCTSDRTILKYMTDGTLHREFLSEP--DLASYSVMIIDEAERTLHTDILFGLVKDIARFRPELKLLISSATL--DAEKFSAFFDDAPI-FRIPGRRYPVDIFYTKAPEADYIDACVSVLQIHATQPLGDILVFLTGQDEIETCQEVLHDRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQ-NNFNSRTGRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGN..................................................`	615
48	-15.000	`[LK] COG1197 Transcription-repair coupling factor (superfamily II helicase)`	`ali follow..`	18	602	`...................................................................EETYDQEMAINAVISDMDRLVCGDVGFGKTEVAMRAAFLAVMNHK---QVAVLVPTTLLAQQHYENFKDRFANLPVNVEVLSRFKTAKEQKQILENKVDILIGT--KLI-----QSDVKFNDLGLLIIDEEHR-----FGVGQKEKIKQLRANIDILTLTATPIPRTLNMAMNGIRDLSIISTPPARRLSIKT-----FVRQNDDLVVREAILREILRGGQVYYLHNDASIENTAEKLTALEARVIVGHGQMRERELERVMSDFYHQRYNVLVCSTIIETGIDVPTANTIIIERADHFGLAQLHQLGRVGRSHHQAYAYLLMTKDAERRLDALENLDN............................................................`	940
49	-14.900	`[L] COG1643 HrpA-like helicases`	`ali follow..`	21	66	`..........................................................AARPSITYPQNLPVKQDILEAIRDHQVVIVAGETGSGKTTQ--LP--KICMELGRGIKGLITQPRRLAARTVANRI---AEELQTEPGGCIG-------SDHVSSNTMVKLMTDGILLAEIQQDR--LLMQYDTLIIDEAERSLNIDFL--LKELLPRRP-DLKVIITSATI--DPERFSRHFNNAPI-IEVSGRTYPVEVRYRPIVEEADDTERDQLQAIFDAESPGDILIFMSGEREIRDTADALNKLHTEVLPLYARLSNSEQNRVFQ--SHSGRRIVLATNVAETSLTVPGIKYVIDPGTPISQASANQRKGRCGRVS-EGICIRLYSEDD---FLSRPEFTDPEILRTNLAS..................................................`	435
50	-14.600	[L] COG1198 Primosomal protein N` (replication factor Y) - superfamily II helicase	`ali follow..`	17	219	`................................................LLESYSREQVNFFVDQGAVT-NPEQRQARDAVVSSIGFLLQGITGSGKTEVY-LQIIQGALDKGK--TAILLVPEISLTPQMTERFIAFGDKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIF--------APLKNLGVMIIDEEH---EAAYKQDAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLATIPEVQVIDFRDYIGQNETSNFTPVKKEQVVLMLNRRGYSSFVSRSIRYYGTGTQKAYDELKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVLNADTALNLPDFTQVAGRSGRAEKAGQVLIQSYNPQHYAIRFAKDQDYEGFYAYEMGIRRQL..............................................`	696
51	-13.400	`[B] KOG0389 SNF2 family DNA-dependent ATPase`	`ali follow..`	16	289	`.........................................................LADYQIIGLNWLTVMHKQEMNGILAD-------EMGLGKTIQ-VIAFLAYLKENGL----LIVVPSSTLDNWEAE-ISRWCP--ELVVEKYHGSQDERRRMRG-FTGFDVLLTTYHIVGSTPEERKMFRVCKLDYVIFDEAHMLKNLCFVMP-KDVLKNLPKKLQKIYYHELVDYYSNNKGRRIANHPLLMRHYFTDANLRGFSKRLALICDSGKFLYLDTLLPKAEGHRVLLFSQFTMMLDIVEEYLRIRKFGFCRLDGATAVNVRQDLITDFNGDD--FLLSTKAGGVGINLTAADTCVIHDIPYQAEDRCHRMGQQ----RPVTIYRLISESTIE-----EGILMAAEEKLKLEKDITSNEKGEVHEQRCVVKLLTTALGLDKDQEEQLNNSLNNSIASPAK...`	844
52	-13.300	`[KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family`	`ali follow..`	19	699	`......................................................QATLRSYQTEGVHWLERLRKMHLNGILAD-DM------GLGKTLQ-AIIAVTQSKLEKGSGCSLIVCPT-SLVYNWKEEFRKFNP--EFRTLVIDGVPSQRRKQLTALADRDVAITSYNLLQKDVELYKSFRFD---YVVLDEAHHILMPGLLSS-EDVLKDLPPVSQKELYQSYAASAKQELSRLVKQEGFERIHIHVLATLTRLKQDAPEPGDSAKYDMLMDLLSSDSGHKTVVFSQYTKMLGIIKKDLESRGIPFVYLDG--STKNRLDLVNQFNEDP--FLISLKAGGTGLNLVGADTVIHYDVENQATDRVHRIGQS----RSVSSYKLVTLNTIE-----EKILTLQNRKKSL....................................................`	1140
53	-11.200	`[R] COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster`	`ali follow..`	13	57	`..........................................SAQLPFRKSDLPLNFFPNLTL----PPHAHQARAFQRLGAPQPTLVATGTGSGKTECFMFPLLNHCAGASQGVKAIIIYPMNALATDQASRFAKTQLHGKVTVGLFVGDSEIEPSKKTLRESPPDILLTNYKMLDYL-RPGDQPLGSLRYLVVDEL-HTFDGAQGSDLACLVRRLNQRFACVGTSATVGGQLLDYAKTIFDQPFT--IREDRYTAAEYLQNYAIAYSQYPGPEVASALDPQSYATPVAYLNGQIPL-------DSDLQLPDDLESDDGREKRIALGSLLRRHSVMHVLLHDLQGGILSERECLENLQVMLAESADHARRVLQSILALIAQARL................................................................................`	430
54	-11.200	`[L] KOG1002 Nucleotide excision repair protein RAD16`	`ali follow..`	13	357	`..............................................................................IILDEAHYIKERRSNTAR-AVFALPLQNRVGELYSLIRFLQIRPCPHCPHNAVRHFCWWNKYVKRAMILLKHKVLKDILLRRTKLGRAADLALPPRIITLRR----DTLDVKEFDYYESLYKNSQAEFNTYIEAIFDLLTRLRQAVDHPYLVVYSNSSTKADTEHKASKTTLKGFRASSILNRIKLDDFQTSTKIEALREEIERDGSAKAIVFSQFTSFLDLINYTLGKCGVSCVQLVGSMTMAARDTAINKFKEDP--FLMSLKAGGVALNLTVASHVFNPAVERQAQDRIHRIGQY----KPIRVVRFIIENTVE-----ERILRLQKKKELV....................................................`	807
55	-11.000	`[R] COG3972 Superfamily I DNA and RNA helicases`	`ali follow..`	13	207	`.....................................................................DQKQRRAALVTIDGPQRIGLA--GSGKTV-ILAMKAAHLHMTRPNDKILVTFFTKSLRSPIKDLVTKFYRHYNIHIRHGWGGSNSSGTYADACRRSGRMPRSYSSARDAAPRNSAQSLEYYDHILIDEGQD-FPDGFYKLCFELAKGDRDKKNIVWACYRNQREVLVAAHALLRPVENSPVALDTDGLPPLIGNFIASSFEKEISWITKEIMGLLPEDIIVVALDDRHMRNYFRYLSESLASHEISVNNIHADPYSEPPFSISGK---ITLSTVYRAKGNEAAVV-FALGVDALSLRLRADRNAAFT-RT-KAWLRVSGLGDSARRVAVEIDTALRNFPHKFKMPDISEIDLIQRDLSKRSIKAKKIRNE..........................`	685
56	-10.500	`[V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases`	`ali follow..`	14	293	`...........................................................................................TGSGKTVTSFK-VAQLLASAPRIKNVLFIVDRIDLIDQTLENFKSFAYAHFKNRIKKVNGRELKREL--KRKGSSQILLISVQGLTKAVKKGLENDDWN-VIIMDEAHRSASGESVKLIKKALKTTREISTHDIFGAIGDGNVLGFDVTYFKPHWVVEHPQEDFSEKDYEKEVYQSDVYRQEGALIAGKREENAFQAMFAVSGKQAAVNYYNIFKSK--PARAYMLDITKRLARKRPYNQGKDRLDLVIVSDQLLTGFDSKFINVIY-MDKMLKEGMLIQAISRTNRT-PHGKVRFYRQGDEMR--EFVENALR............................................................`	698
57	-10.400	`[KL] KOG0387 Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain)`	`ali follow..`	15	203	`.VTAAIDDGDDLVYRQRLNAWCANRKELRDQASASENNKDRGEFEGKDEWLLPHPSKKGQTFEGGFTIPGDIRPHLFRYQVTCVQIIG--EMGLGKTIQ-IVSFLSSLHHSGK---ALIVCPATLMK-QWVNEFHTWWA--PLRVVVLHATGSGQRASREKRTRGHILITTYAGL---RIYGDLILPREWGYCVLDEGHKIRNPD--SEISISCKQIRTVNRIILSGTPIQNNLTELWNLFMKLDVAADLPKKSEQVTPLQRKAYDPEKSGKLKVIRALLTKKQGHRTLLFSQTRQMLDILEIGLKDPDVHYCRMDGSTSIALRQDLVDNFNKNEYFFLLTTRVGGLGVNLTGADRVILFDPDWNPSTDAQARERAWRLGQK-VVYRLMTAGTIE-----EKIYHRQIFKQFLTN..................................................`	771
58	-9.930	`[V] COG3587 Restriction endonuclease`	`ali follow..`	14	1	`............................................................MSGFNYEKNQPHQMRAVSAVLG-NILDISMETGTGKTYTY-TQTMFELHRWLGVFKFIVVVPTLSIKAGTQQFLQSKALAEHFE---DFGGDYEGVRLKTYKKEIHVLLINAGMVVDALAAVRPF-------MIVDEPHKFPTRDSAKTWGNIKRLKPQ---ILRYGATFNDEYYNLNDGLVKGVRVFQEEMQGGMDAAMQRAVAEHFKLERALLAERAPQPKIKPLTLFFIDDTESDPFYRDYLQKTLDDVSACHGNEILHDKEKLLS--LDNPRRFIFSKWTLREGWDNPNVFQICKLRSSGSTTSKLQEVGRGLRVNELMARVRFVDSSEKDFVKQLVGEINDN..........................................................`	576
59	-9.900	`[KL] COG4646 DNA methylase`	`ali follow..`	13	623	`..........LKVEDEDRVSRKRLERLKEGLQERLEALSTRKDDLLTIAEIGVDQIIVDEAQEF----------RKLSFATNMSTLKGVDPNGSQR--AWDLYVKSRFIETINPGRALVLASGTPITNTLGEMFSTFGDTTTELELQPSRKYKPVSRFASFVNVPELI----RSFAD-VVMPADLREYVKVPAISTGRRQIVTSKPTQAFKHYQMVLAERIKAILLSVITDGRHAAIDLRLVDADNDNEADNKLNNLISNAFNIWKATEGSTYLRHDGKSFELTGAAQMIFSDLGTISRWIRDELIRLGVPASQIQDFKKSEAKQRLFGDVRAGSVRFLISSETMGTGVNAQLLKALHHLDVPWLPSQIEQREGRIVRQGNQHDEVDIFGSLDATMWQNNER...............................................................`	1056
60	-9.520	`[U] COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase)`	`ali follow..`	15	17	`VKTLATRVAKINAYEAEYAALSDEALKGKTAEFKARLEKGETLDDILNEAFAVVREASKRVLGM-----RHFDVQMVGGMVLHFSGISEMRTGEGKTLVATLPTLNALEGKG----VHVITVNDYLARRDADWMGQVYNFLGLSYGVIVNGLSQGERQRAYR--SDITYGTNNEFFDYLRDNLVYSVDEHNFAIVDEVDSILEDGYTRDKDYIVKDIQPENQTL-MTGTASTEAQEFDDIYKMSVSEIPTNRTIQRIDDDDEVYRTEREKNEAILKQIADCHVRGQPILVGTVSIEKSEELSKLLKVKGIPHQVLNARFHEQEAVIVADAGVPGA--VTIATNMAGRGTDIAQALAAGGLFVLGTERHESRRIGRTGRQGDPGRSKFFLSCEDDLLRIFAGERLDAIMRTFGVQEGEAITHKWLNNAIATAQKRVEQRNYEIRKN....................`	656

FFAS is supported by the NIH grant R01-GM087218-01

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