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Query: [R] KOG0394 Ras-related GTPase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPSRRRTLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVQFEDRLFTLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVNSMKSFENLNNWREEFLIQASPSDPENFPFVLIGNKVDVDDGNSRVVSEKKAKAWCASKGNIPYFETSAKVGTNVEEAFQCIAKDALKSGEEEELYLPDTIDVGTSNQQRSTGCECLast
1 -96.300[R] KOG0394 Ras-related GTPase  ali  100  1MPSRRRTLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVQFEDRLFTLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVNSMKSFENLNNWREEFLIQASPSDPENFPFVLIGNKVDVDDGNSRVVSEKKAKAWCASKGNIPYFETSAKVGTNVEEAFQCIAKDALKSGEEEELYLPDTIDVGTSNQQRSTGCEC 206
2 -84.100[TU] KOG0084 GTPase Rab1/YPT1, small G protein superfamily, and related GTP-binding proteins  ali follow..  37  1MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDSYLDSYISTIGVDFKIRTVEQDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVTYDVTDLESFNNVKQWLNEIDRYAS----ENVNKLLVGNKCDLTS--QKVVSTETAKAFADELG-IPFLETSAKNATNVEEAFMAMTAAIKTRMASQPAGGSKPPTVQIRGQPVNQQSGC 199
3 -84.000[U] KOG0095 GTPase Rab30, small G protein superfamily  ali follow..  33  3.MEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVGFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYAS----NKVITVLVGNKIDLAE--RREVSQQRAEEFSEAQD-MYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGEGKSISYLTCC 200
4 -83.600[TU] KOG0078 GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins  ali follow..  36  3.TKSYDYLIKLLLIGDSGVGKSCLLLRFSEDSFTPSFITTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLLYDVTDKKSFDNVRTWFSNVEQHAS----ENVYKILIGNKCDCED--QRQVSFEQGQALADELG-VKFLEASAKTNVNVDEAFFTLAREIKKQKIDAENEFSNQANNVDLGNDRTVKRCC 200
5 -83.100[R] KOG0079 GTP-binding protein H-ray, small G protein superfamily  ali follow..  35  4.TRDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSENYITTIGVDFKIRTMDINGQRVKLQIWDTAGQERFRTITSTYYRGTHGVVVVYDVTNGESFGNVKRWLQEIENNC-----DSVQKVLVGNKCEENE--RRVVLESDARNYAQSMN-ISFFETSAKEDKNVEPMFTCITSLVLTAKLANPQSASKSLKDNSGSTNQKKKCKC 208
6 -82.800[U] KOG0086 GTPase Rab4, small G protein superfamily  ali follow..  33  1MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLAS----PNIVVILCGNKKDLDP--EREVTFLEASRFAQENE-LMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMRQPRSAQAVAPQPCGC 213
7 -82.700[R] KOG0080 GTPase Rab18, small G protein superfamily  ali follow..  31  1MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTR---NDIVNMLVGNKIDKEN---REVDRNEGLKFARKHS-MLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQKGVKLSHREEGQGGGACG 200
8 -81.900[U] KOG0097 GTPase Rab14, small G protein superfamily  ali follow..  34  5.PYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTN----PNTVIILIGNKADLEA--QRDVTYEEAKQFAEENG-LLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAGGRLTSEPQPQREGCGC 215
9 -81.800[R] KOG0088 GTPase Rab21, small G protein superfamily  ali follow..  31  5NVDQKSFKFKIVLLGEGCVGKSSLVLRFVENKFSCKHLSTIQASFQNKTVNVEDCQADLHIWDTAGQEKYHALGPIYYRGSNGVLLVFDITDRKSFEKVKNWVLEIKTCLG----NTAEILIVGNKIDLEE--ERQVTRQDAEAYAESEG-ALYMETSAQDNVGISDAFESLTAKMIEHSRTRSTEPPSSIRLIDNDEAERSKKCC 206
10 -81.800[U] KOG0092 GTPase Rab5/YPT51 and related small G protein superfamily GTPases  ali follow..  35  13NTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQAS----PNIVIALSGNKADLAN--KRAVDFQEAQSYADDNS-LLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSRGVDLTEPTQPTRNQCC. 213
11 -81.600[U] KOG0093 GTPase Rab3, small G protein superfamily  ali follow..  30  15SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSW----DNAQVLLVGNKCDMED--ERVVSSERGRQLADHLG-FEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPGPQLSDQQVPPHQDCAC 220
12 -81.400[U] KOG0094 GTPase Rab6/YPT6/Ryh1, small G protein superfamily  ali follow..  36  3.SVSPLAKYKLVFLGDQSVGKTSIITRFMYDKFDTTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDVANRLSFLNTSKWIEEVRNERA----GDVIIVLVGNKTDLVE--KRQVSIEEGDSKGREYG-VMFIETSAKAGFNIKPLFRKIAAALPGMESYSNTKNEDMVDVNSQGDQQGGACSC 207
13 -81.300[U] KOG0081 GTPase Rab27, small G protein superfamily  ali follow..  39  3.DGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYC---ENPDIVLCGNKSDLED--QRVVKEEEAIALAEKYG-IPYFETSAANGTNISQAIEMLLDLIMKRMERCVDKSWIPSTDQLSEEKEKGACGC 221
14 -80.700[R] KOG0091 GTPase Rab39, small G protein superfamily  ali follow..  31  2VEPIFEYQFRLILIGDSTVGKSSLLKFFTDGKFAELSDPTVGVDFFARLIEMDGTQIKLQLWDTAGQERFRSITKSYYRNSVGVLLVYDISNHASFEHIPLWMMEAQRHIEP---HRPVFALVGCKLDLINGGHREVTTEEAQKFAKQHG-LHFVETSARSGANVEEAFRMVTQEVYARIRSGEYKAEDGLDFNLVVAEPEKSSCC 218
15 -79.600[U] KOG0087 GTPase Rab11/YPT3, small G protein superfamily  ali follow..  33  4.EDEYDYLFKTVLIGDSGVGKSNLLMRFTRNEFNIESKSTIGVEFATRNIVLDNKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDITKQSSFDNVGRWLKELREHAD----SNIVIMLVGNKTDLLH--LRAVSTEEAQAFAAENN-LSFIETSAMDASNVEEAFQTVLTEIFRIVSNRSLEAGDDPTMNDLNKKKSSSQCC 214
16 -79.200[U] KOG0098 GTPase Rab2, small G protein superfamily  ali follow..  33  2...SYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSN----SNMVIMLIGNKSDLEA--RREVKREEGEAFAREHG-LVFMETSAKTAANVEEAFIDTAKEIYRKIQEGVFDINNEAN-NATGGLGGGSGCC 214
17 -77.000[T] KOG4252 GTP-binding protein  ali follow..  29  2LEEDMEVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRGSFEAVSSWREKVVAEV-----GDIPTVLVQNKIDLLD--DSCIKNEEAEALAKRLR-LRFYRTSVKEDLNVNEVFKYLAEKYLQKLKQQIAEDPELFNTSGGSHSGQNSGTL 209
18 -73.400[U] KOG0096 GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily  ali follow..  27  6.ANGEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVC-----ENIPIVLCGNKVDVKERK----VKAKTITFHRKKN-LQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEMQQYQQEMEQAT 207
19 -69.000[R] KOG0395 Ras-related GTPase  ali follow..  25  12LSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIE-DFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSTKEAAELPMVICGNKNDHGE-LCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFC.. 218
20 -67.900[R] KOG1673 Ras GTPases  ali follow..  20  95.SDSDLVSLKISLLGDCQTGKTTFVVKYVGDEN-QSFLEMTGLNLMDKTFYVQGVTISFSIWDVGGDERSKDHIPIACKDAVAILFMFDLTSRSTLNSVFGWYSQARKWN-----KTAIPILIGTKFDDFPPNLQWTIVTQARAYAKVMN-ASLFFSSATHNINVNKIFKFILARLFNLPWKIDRNLTLG................ 280
21 -66.100[R] KOG0083 GTPase Rab26/Rab37, small G protein superfamily  ali follow..  35  462.EDEFDIMGKVIMLGDSGVGKTSLLIRFRDGRYVPSYLSTVGIDFRNKVVVVDGTRVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKTTYDNIRAWLGEIREYAQ----EDVVIVLIGNKADCSG-SERQVKREDGERLGREHN-VPFMETSAKTGLNVELSFTAVARQLKSRGYEHGDDGKFNVHDFVRDNTKARSVCA 661
22 -49.400[R] KOG0393 Ras-related small GTPase, Rho type  ali follow..  24  4........IKCVVVGDGAVGKTCLLLSYTTNAFPGEYILTV-FDTYSTNVMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLVCFALNNPASFENVAKWYPEVSHHC-----PNTPIILVGTKADLREDRLQPVSHTQGYVMAKEIKAVKYLECSALTQIGLKQVFDEAIRTGLTPPQTPQTRAKKS................ 190
23 -47.300[R] COG2229 Predicted GTPase  ali follow..  20  4........NKIIFTGPVGVGKTTAIAAISDEALVQTDATTVAMDYGAISL---DEDTKVHLYGTPGQERFNFMWEILSQGSMGLVLLLDNARTNPLKDLEFFLHSFRGLL-----EKAPVVVGITKMDIRSQPG---IDVYHKYLAKHNLNVPVFEIDARKEDDVKQLVSAMLFSIDPGLE......................... 177
24 -35.300[T] KOG3886 GTP-binding protein  ali follow..  17  33VLPNTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDLGATILDRIHSLQINSSLGNLVLNLWDCGGQDTFMSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNS--PDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQ........................ 247
25 -33.400[R] KOG0075 GTP-binding ADP-ribosylation factor-like protein  ali follow..  19  21........MELTLVGLQFSGKTTFVNVIASGQFAEDMIPTVG--FNMRKITRGN--VTIKVWDIGGQPRFRSMWERYCRGVNAIVYMVDAADLDKLEASR---NELHSLLDKPQLAGIPVLVLGNKRDLPGALDETGLIERMNLSSIQDREICCYSISCKEKDNIDITLQWLIQHSKSQSR......................... 186
26 -31.800[S] KOG4273 Uncharacterized conserved protein  ali follow..  15  2.....ESRPGVLVVGSSGVGKRTLLSRLLSVEFEDSSESSSQTEVHGWTINTKYYTADVSVCISHICDEYSLPNLPNSHPLVALVMVFDLSELSTLVALQDWVSHTDINSFD------ILLCIGNKVDRVP--HHLAHDEYRRRLLKDIDDFGISETEGSSLLGSEDASLDIRGACLE............................ 176
27 -31.200[R] KOG0074 GTP-binding ADP-ribosylation factor-like protein ARL3  ali follow..  21  18........VRILLLGLDNAGKTTLLKQLASEDIS-HITPTQG--FNIKSVQSQG--FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETG---QELAELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAKKK......................... 182
28 -30.800[U] KOG0071 GTP-binding ADP-ribosylation factor Arf6 (dArf3)  ali follow..  17  22........MRILMLGLDAAGKTTILYKLKLNQSVVT-IPTVG--FNVETVTYKN--IKFNVWDVGGQDKIRPLWRHYFTGTKGLIFVVDSADSNRISEAR---QELHRIISDREMRDCLLLVLANKQDLPGALSPAQITDVLQLDKLKDRLWNVQPTCALTGDGLLEGLAWLSQNAKLK........................... 184
29 -30.800[V] KOG1707 Predicted Ras related/Rac-GTP binding protein  ali follow..  15  8.SSGSPKPIRIVVVGEKGSGKSSLIMAAARNTFHPNIPSLL--PYTNLPSEFFPDRIPATVIDTSSRPEDKGKVVKEVRQADAIVLTFAFDRPETLDRLSKWLPLFRQLE-----VRVPIIVAGYEVDNKEAYNHSIEQITSALMKQYREVETSIQWSAQRLDQAKDVLYYAQKAVI............................. 178
30 -30.700[U] KOG0072 GTP-binding ADP-ribosylation factor-like protein ARL1  ali follow..  20  18........MRILILGLDGAGKTTILYRLQVGEVVTT-IPTIG--FNVEQVTYKN--LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSADRDRIGISK---DELLYMLREEELAGAILVVLANKQDMDGCMTVAEVHHALGLENLKNRTFQIFKTSATKGEGLDQAMDWLSNTLQSRK.......................... 181
31 -30.600[U] KOG0070 GTP-binding ADP-ribosylation factor Arf1  ali follow..  15  18........MRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVET----VEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEAR---DELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNIASK........................... 180
32 -30.200[UZ] KOG0073 GTP-binding ADP-ribosylation factor-like protein ARL2  ali follow..  18  17........LRLLMLGLDNAGKTTILKKFNGEDID-TISPTLG--FNIKTLEHRG--FKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQ---RELQSLLVEERLAGATLLIFANKQDLPGALSSNAIREALELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRIFTAD...................... 184
33 -30.200[R] COG1100 GTPase SAR1 and related small G proteins  ali follow..  18  19........LRILILGLDGAGKTTILYRLQIGEVVTT-KPTIG--FNVETLSYKN--LKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKDRMSTAS---KELHLMLQEEELQDAALLVFANKQDQPGALSASEVSKELNLVELKDRSWSIVASSAIKGEGITEGLDWLIDVIKEEQ.......................... 182
34 -29.600[U] KOG0076 GTP-binding ADP-ribosylation factor-like protein yARL3  ali follow..  15  18........YSILILGLDNAGKTTFLETLKKEYSLAKIQPTVG--QNVATIPVDSKQI-LKFWDVGGQESLRSMWSEYYSLCHGIIFIVDSSDRERLDECS---TTLQSVVMDEEIEGVPILMLANKQDRQDRMEVQDIKEVFNKIAEHISARDSLPISALTGEGVKDAIEWMIVRLERNKKSRP...................... 194
35 -28.500[U] KOG0077 Vesicle coat complex COPII, GTPase subunit SAR1  ali follow..  17  21........AKILFLGLDNAGKTTLLHMLKDERLV-QHQPTQH--PTSEELSIGK--IKFKAFDLGGHQIARRVWKDYYAKVDAVVYLVDAYDKERFAESK---RELDALLSDEALATVPFLILGNKIDIPYATNFTTGKGKVTLGDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYI.............................. 192
36 -24.400[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  18  57.........TVLLSGLSGSGKTVLFYQLRDGSSHQGAVTSMEPNEGTFVLTKKGKVKPVHLIDVPGHSRLISKLEEYLPRAAAVVFVVDALELPNIRAASEYLYDILTNASVIK-NKTPVLLCCNKTDKVTAHTKEFIRKQMESFSHCHNKVTVAEASGLTG-ETDQVQEFIREHV.............................. 258
37 -19.400[U] KOG3887 Predicted small GTPase involved in nuclear protein import  ali follow..  16  64.........RILLMGLRRSGKSSIQKVVFHKMSPNELESTNKIC--REDVSNSSF-VNFQIWDFPGQIDFFDPTEMIFRGTGALIFVIDSQDDYMEALAR----HLTVTRAYKVNTDINFEVFIHKVDGLSDDHKIETQRDIHQRANDD-HLSFYLTSIYDH-SIFEAFSKVVQKLIPQLP......................... 242
38 -19.200[E] COG4917 Ethanolamine utilization protein  ali follow..  16  1.......MKRIAFVGSVGAGKTTLFNALQGNYTLARKTQAVEFN-------------DKGDIDTPGHPRWYHALITTLQDVDMLIYVHGANDPES----------RLPAGLLDIGVSKRQIAVISKTDMPDADVAATR----KLLLETGFEEPMFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHSE................. 159
39 -17.900[R] COG1084 Predicted GTPase  ali follow..  16  155MPTVDLDAFTVVIAGFPNVGKSTLLRTLTGAEPEVADYPFTTKGIQIGHLERKWK--RIQVIDTPGNNIELQAMVALENIADVIMFIFDASETCGYTLE----SQYSLYLGIRSVFDIPVVTVFNKMDLAENVKYLEEYINMVE--------DPLKVSAFEGRGVSKIIKKLEGLYEKETREAHDN.................... 335
40 -17.800[R] COG0218 Predicted GTPase  ali follow..  16  27.........EIALAGRSNVGKSSFINTMLNRKNLARTSGKPG---KTQLLNFFNIDDKMRFVDVPGREKWGCMIEEYLTTREAVVSLVDLRHDPSADDVQEFLKY----------YEIPVIIVATKADKIPRGKWNKHESAIKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL.............................. 195
41 -17.500[R] KOG2486 Predicted GTPase  ali follow..  16  137.........EFALVGRSNVGKSSLLNSLVRRKRLALTSKKPG---KTQCINHFRINDKWYLVDLPGKQDWNKFTKDYFLNLVSVFLLVDASIPVK-LEYASWLGQ----------NQVPMTLIFTKCDKRKKKKNGGKKPEANIKEFQDTTPPWIMTSSVTNQGRDEILLHMAQLRNYWLKH........................ 318
42 -16.100[R] COG3596 Predicted GTPase  ali follow..  11  40.........VIGIMGKTGAGKSSLCNALFAGE-VSPVSDVAACTRDPLRFRLQIGEHFMTIVDLPGDTEYAALYREQLPRLDLILWLIKADDRALATDEHFYRQVIGEAYRHK------MLFVISQSDKSTEQKQNISRKICLLHELFQPVHPVCAVSVRLQWGLRVMAERMIKCLPREPSS........................ 222
43 -15.200[R] KOG1489 Predicted GTP-binding protein (ODN superfamily)  ali follow..  15  332FLFELKSIADLGLIGLPNAGKSTILNKISNAKPKIGHWQFTTLSPTIGTVSLGFGQDVFTVADIPGASLDKGMGLEFLR-SNGWVFVLDLSNKNPLNDLQLLIEEVGTLEKVKTK---NILIVCNKVDIDAEKSESFAKYLQVEKFSKSQEWDCVPISALREKT.......................................... 499
44 -14.700[J] KOG0462 Elongation factor-type GTP-binding protein  ali follow..  16  40.....DKIRNFGIVAHVDHGKSTLADRLLEGAVPPGQKQMLGITVKAQTAALRHRGYLLNLIDTPGHVDFSAEVSRSLAVCDGILLLVAANQGVQAQTIANFWLAFEK--------NIQIIPVINKIDLPGADIKSVETQLKNLFEFNPEEC--LHISAKSGLNVDKVLEAIIDRV.............................. 211
45 -14.400[M] COG0481 Membrane GTPase LepA  ali follow..  18  2.....KNIRNFSIIAHIDHGKSTLSDRLIQTC-SMDLERERGITIKAQSVTLDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEM--------NLEVVPILNKIDLPAADPERVAEEIEDIVGIDAMEA--VRCSAKTGVGIEDVLEEIVHKI.............................. 180
46 -13.600[R] KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily)  ali follow..  17  171..........VLICGYPNVGKSSFMNKVTRAD-----VDVQPYAFTTKSLFVG-KYLRYQVIDTPGRNIIEMCSITALAHLRAAVLFFLDISGSCGYTIAQQAALFHSIKS----MNKPLVIVCNKTDLMPMENEEMKSEAMKTAMGASEEQVLLKMSTLTDEGVMSVKNAACERLLDQRVEAKMKSKK................. 362
47 -12.800[R] COG1160 Predicted GTPases  ali follow..  17  216........IKIAIVGRPNVGKSTLTNRILGED-RVVVFDMPGTTRDSIYIPMERDGQQYTLIDTAGVRKRGKVHLAVIQDANVVLLTIDARENISDQDLS---------LGFILNAGRSLVIVVNKWDGLDQDVKDRVKSELDRRLDFIDFARVHFISALHGSGVGNLFDSIKEAYACATQK........................ 391
48 -12.800[OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase  ali follow..  19  4.......PLIIGVGGPVGAGKTMLIERLTRYLSTKGYSAAITNDIYTEEMCDKHPDLQLLFLESGGD----LSATFSPDLVDFSIYIIDVAQGEKIPRKGGQGMIKSD------------LFIINKVDLAPYVGANVEVMK-ADTLKSRGNKDFFVTNLKTDEGLKSVADWIEKRLQLALLEE....................... 206
49 -12.700[J] KOG1191 Mitochondrial GTPase  ali follow..  19  354........LQIAIVGRPNVGKSSLLNAWSERAIVTEVAGTT--DVVEANVTVRG--VPITLLDTAGIRETNDISETAAKVADVIIMAVSAVEGWTEEDTE--GVSFYDLFGGLLYLKQPMILVMNKIDCAPPGS---CDQLEDQRKKEEVFHKSVFTSAVTGQGIEELEDAILEIL.............................. 533
50 -12.700[R] KOG0410 Predicted GTP binding protein  ali follow..  19  303.RRVAIPVPVVSLVGYTNAGKSTLLNQLTGANVLAENRLFATLDPTTRRVQMQNGK-EFLLTDTVG-AAFRA-TLEEIAESSLLVHVVDISHPLAEQQI----EAVEKVMSELDVSSIPKLVVWNKVDRVDDPQKVKLEAEETGDT--------ICISALTGEGLDDFCNAVHEKLKDSMVWVEALLP.................. 484
51 -12.600[J] COG3276 Selenocysteine-specific translation elongation factor  ali follow..  20  1...........MIIVTSG-GKTALLKALTTAHLPEEKKRGMTIDLGYAYLPLENKVLGF---DVPGHEKFLSNMLAGLGGVHYAMLIVAADEVQTKEHL-----AILRQLQFHEI-----IVVITKADRTNSAQIESLIQTIKQDYSFLRNANYFVTSAETGQGISELRHYLANLAELADTQK....................... 169
52 -12.500[J] KOG1145 Mitochondrial translation initiation factor 2 (IF-2; GTPase)  ali follow..  19  183..........VTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGE-KITFLDTPGHAAFSAMRA---RGAQVTDIVVLVVAAD--DGVMKQTVESIQHAKDA---QVPIILAVNKCDKAEADPEKVKKELLAY--DYGGDVQAVPVSALTGDNLMALAEATV................................. 339
53 -11.900[R] COG0486 Predicted GTPase  ali follow..  20  228........MKVVIAGRPNAGKSSLLNALAEAAIVTDIAGTT--DVLREHIHIDG--MPLHIIDTAGLREATDEAWSEIEQADRILLMLDSTEADNQDL-----EKVRSEFLTKLPSNIPVTIVRNKADLSGENEGI----------VEQNGYTVITLSAKTQQGIALLREHLKQSMGYQTNMEG...................... 395
54 -11.500[T] COG1217 Predicted membrane GTPase involved in stress response  ali follow..  15  3.....ENLRNIAIIAHVDHGKTTLVDKLLKLS-SNDQEKERGITILAKNTAIKWNGYNINIVDTPGHADFGGEVERVMSMVDSVLLVVDAQDGPMPQTRFVTQKAFKA--------GLRPIVVVNKIDRPGARPDWVIDQIFDLFDNLGATDEQLDFPIVYASALN........................................ 169
55 -11.400[R] COG2262 GTPases  ali follow..  18  191.SRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRIDVADVG-ETVLADTVG-AAFKA-TLQETRQATLLLHVIDAADVRVQENI----EAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENK--------IRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLP.................. 373
56 -11.300[R] COG1159 GTPase  ali follow..  15  1MSTDKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGI-HTEGPYQAIYVDTPGNRLMNKAASSSIGDVELVIFVVEGTR---------WTPDDEMVLNKLRDGKAPVILAVNKVDNVQEKVDLLPH--LQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHL.............................. 173
57 -11.300[J] KOG0468 U5 snRNP-specific protein  ali follow..  13  124LMDTPPLIRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEEGCSIKATPVTLKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQ--------ERQAITVCINKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDN......................................... 300
58 -11.300[P] COG2895 GTPases - Sulfate adenylate transferase subunit 1  ali follow..  16  20IAQQHKSLLRFLTCGSVDDGKSTLIGRLLVDGLQAEREQGITIDVAYRYFSTEKRKFII---DTPGHEQYTRNMATGASTCELAILLIDARKGV--------LDQTRRHSFISTLLGIKHLVVANKMDLVDYSEETFTREDYLTFAGQLPDIRFVPLSALEGDNVAS....................................... 215
59 -11.200[J] KOG0458 Elongation factor 1 alpha  ali follow..  20  162..KSALPHLSFVVLGHVDAGKSTLMGRWIMDQTNEERERGVTVSICTSHFSTHRANFTI---DAPGHRDFVPNAIMGISQADMAILCVD-CSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIANKMDNVDWSQQRFEESKLLPYLVDIGNINWVPISGFSGEGVYK....................................... 361
60 -11.200[TU] KOG1954 Endocytosis/signaling protein EHD1  ali follow..  15  95..........ILLVGQYSTGKTTFIRYLLESDFPGRALSGFGNAFLNRCSTLPNQVLEVTIVDTPGIDRFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDK-------IRIVLNKSDM-----------DHQQLMRVYGALMWSLGKVFKTPEVSRVYL.................................... 288
61 -11.100[J] COG4108 Peptide chain release factor RF-3  ali follow..  15  8YFGEVSKRRTFAIISHPDAGKTTITEKVLLFGRAIQVAGTVGISVTTSVMQFPYGDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLM--------EVTRLRDTPIVTFMNKLDREIRDPMELMDEVENELKIACSPITWPIGCGKEFKGVYHIHRD................................... 190
62 -10.800[R] KOG1533 Predicted GTPase  ali follow..  12  26LGSTHWTMYGVLVIGAPGAGKSTFCAGLTD-SQTKRPFLTINLDPANDTMKIEANHKKYLIIDCPGQELYWKVIRFLEKSGVRLCALH-LADSLYCSDPSKFISVALSTLATMVTMEMPQVNCLSKADLFSEDKYRKLNEAICGVISDFDLVSFVPLAVENKESMMKVIQMVDAAN.............................. 281
63 -10.800[J] KOG0466 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  13  42........INIGTIGHVAHGKSTVVKAISTVRFKNELERNITIKLGYANAKI-RLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKH------ILILQNKIDLVKERQAKEQYEQILAFVQGTVGAPIIPISAQLKYNIEVVCEYIVKKI.............................. 243
64 -10.800[H] COG3172 Predicted ATPase/kinase involved in NAD metabolism  ali follow..  14  2.EVKPFFVRTVAILGGESSGKSTLVNKLAN-IFNTTSAWEYGRDYVFSHLGGDEIALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALIDEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEEEEDYDSRFLRCVELVREMMGEQR...................... 187
65 -10.800[J] COG0532 Translation initiation factor 2 (IF-2; GTPase)  ali follow..  20  448..........VTIMGHVDHGKTTLLDRFRESRVTEGEAGGITQHIGAYQIKANGKKITF---DTPGHEAFTSMRA---RGASVTDITILVVAAD--DGVMPQTIEAINHSKAA---GVPIIVAINKIDKPGANPQRVTQELTEH---PENGSEFVEISAKFNQNLDELLDTVL................................. 605
66 -10.800[P] COG0370 Fe2+ transport system protein B  ali follow..  19  4........NTYCILGNPNTGKTSLFNALTGSY--EYVGNWSGVTVEKKVGTLRSKTGKL-IYDLNPISRDETVVTRFLEKFDCMLNIVDSSQIERNLNLTVQLLEY----------GAPVVMGLNMIDVAAGRGIHLNIQNLAKKL----RIPILPVVARSGKGTEDILSTLSEKHVAPAIPLVLQYGEPAE.............. 177
67 -10.700[J] KOG0469 Elongation factor 2  ali follow..  16  12LMDRKRNIRNMSVIAHVDHGKSTLTDSLVSKA-TRKDEQERCITIKSTAISLKYNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIA--------ERIKPVLFMNKMDRALLELQLGAEELFQTFQRIVENINVIIATYGDDDGPM........................................ 211
68 -10.700[K] KOG1534 Putative transcription factor FET5  ali follow..  10  4........VAAFVCGVASSGKSTFCGALMS-KSVGRSCHLVNLDPAAENFEIGDYDEDYLIFDMPGQELYPALIRHLQVTLNFRPCAVYLLESQFLVDRTKFFAGVLSAMSAMVMMEVPHINLLSKMDLLKDNNNI--NRCIVQLIDDFNMVNFLPLESGNEESVSRVLSYIDDATQWYEDQEPKDPDRFEADDLEDDE....... 276
69 -10.500[J] KOG0459 Polypeptide release factor 3  ali follow..  16  95.EANKKRHLNVVFIGHVDAGKSTIGGQYIMDTNEEERLKGKTVEVGRAHFETESTRFTI---DAPGHKSYVPNMISGASQADIGVLVIS-ARKGEFETGYERGGQTREHVQLAKTLGVSKLIVVNKMDDPTVNWSKERYDEIEQ--NTKKDVVFLPISGLMGKNMDQ....................................... 298
70 -10.300[J] KOG0052 Translation elongation factor EF-1 alpha/Tu  ali follow..  18  1MGKEKVHI-NIVVIGHVDSGKSTTTGHWVLDKLKAERERGITIDIALWKFETAKYYIT--IIDAPGHRDFIKNMITGTSQADCAVLVVA-CGTGEFEAGISKNGQTREHALLAQTLGVKQLIVANKMDSTEPPFSEARFTEIKKIGYNPKAVPFVPISGFNGDNMLE....................................... 203
71 -10.200[J] COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  17  5.........SEINIGLVG-GKTTLTKALSTDTHSEETKRGISIRLGYADITFRKLLRKVSFVDAPGHETLMATMLSGAALMDGAILVIAANEPCPQPQTKEHLMALDVIGVKD------VIVVQNKIDIVSKERALESYREIKEFVKGTEDAPIIPVSAQQGANIDILIETIEERI.............................. 197
72 -10.100[R] COG0536 Predicted GTPase  ali follow..  14  152LILELKSMADVGLVGFPSAGKSSLISVMSAAK--TTLQPNLGV--------VNVGHETFTMADVPGASEGKGLGLDFLRHIERTSVLVHVVDTATMDELAAYQSALDEDTGLGDLSQRPRLVVLNKADVPEAEELA---EFLKEDIEKQFGWPVFIISAVARKGLDPLKYKLLEIVQDARKKRPKEKAES................ 354
73 -9.620[O] KOG0448 Mitofusin 1 GTPase, involved in mitochondrila biogenesis  ali follow..  17  76........MKVAFFGRTSSGKSSVINAMLWDKVSDEKKSVKTVNQLAHALHMDKDLKALVLVDSPGTTELDSWIDKFCLDADVFVLVANSESTLM-NTEKHFFHKVNEWLSKPN-----IFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVANALEAQNRIFFVSAKEVLSARKQKA...................... 296
74 -9.580[F] COG1618 Predicted nucleotide kinase  ali follow..  13  3IEGKEKTMLRIAVTGSPGVGKSTVVAKTAEKLAEKPGFKIGG--IRTAEIRKEGHREGFSIRDLATGKTGRIGANAVRNALACDLVVID-----EIGPMELISQSFVSAVEEVLESDKPVLAVLHHSSRHPLAQRF------------RKGFEVLTVDKGNRDELPEKITNRFLRKLG............................ 184
75 -9.340[DZ] COG5019 Septin family protein  ali follow..  15  89.CVRQGFNFNVLVLGESGSGKSTLVNTLLNRDVGVNPEPTVMINSSAVEIVENGISLQLNVIDTPG----------------------FIDNTDCWQPVLTDIEGRYDQYLELEKHNPRSTIQDPRVHATGHAISAMELRVMLALHEKVNIIPII---AKADTLTDDELNFTKEMILRDIQYHNIR.................... 270
FFAS is supported by the NIH grant R01-GM087218-01
1 3 6 3 0 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Veeramalai M, Ye Y, Godzik A. TOPS++FATCAT: fast flexible structural alignment using constraints derived from TOPS+ Strings Model. BMC Bioinformatics. 2008 Aug 31;9(1):35