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Query: [O] KOG0421 Ubiquitin-protein ligase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MATVNGYTGNTPAATTPAATGSKQSAPPTKTVDSHSVLKRLQSELMGLMMGADPGISAFPEEDNIFCWKGTITGSKDTVFEGTEYRLSLTFSNDYPFKSPKVKFETCCFHPNVDLYGNICLDILQDKWSSAYDVRTILLSIQSLLGEPNISSPLNNQAAQLWSNQEEYRKMVEKLYKPLNALast
1 -102.000[O] KOG0421 Ubiquitin-protein ligase  ali  100  1MATVNGYTGNTPAATTPAATGSKQSAPPTKTVDSHSVLKRLQSELMGLMMGADPGISAFPEEDNIFCWKGTITGSKDTVFEGTEYRLSLTFSNDYPFKSPKVKFETCCFHPNVDLYGNICLDILQDKWSSAYDVRTILLSIQSLLGEPNISSPLNNQAAQLWSNQEEYRKMVEKLYKPLNA 181
2 -92.500[O] KOG0419 Ubiquitin-protein ligase  ali follow..  42  1................................MTTPAKKRLMWDFKRLQKDPPVGISGAPQDNNIMHWNALIFGPEDTPWDGGTFKLTLHFTEDYPNKPPIVRFVSRMFHPNIYADGSICLDILQNQWSPIYDVAAVLTSIQSLLCDPNPDSPANAEAARLFSNKREYNRKVIEIVEQSYV 150
3 -91.400[O] KOG0417 Ubiquitin-protein ligase  ali follow..  37  1...................................MATRRILKELKELQRDPPVSCSAGPTGEDMFHWQATIMGPNESPYSGGVFLVNIHFPPDYPFKPPKVVFRTKVFHPNINSNGNICLDILKDQWSPALTISKVLLSICSLLTDPNPDDPLVPEIAHIYKDKTKYEAMARSWTQKYA. 146
4 -87.400[O] KOG0418 Ubiquitin-protein ligase  ali follow..  32  1................................MSNIAFNRLQRECKEVVTNSETGIMIEILNENLTEIKGHIRGPPDTPYAGGMFDLDIKIPDQYPFSPPNVKFSTKIWHPNVSSQGVICLDILKDQWAASLTLRTVLLSIQALMCTPEPKDPQDAVVAKQYMKPAVFKATAEYWTTKFAK 154
5 -86.500[O] KOG0424 Ubiquitin-protein ligase  ali follow..  38  1................................MSGIALSRLAQERKAWRKDHPFGFVAVPTKNNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCNRVEYEKRVRAQAKKFAP 157
6 -85.100[O] COG5078 Ubiquitin-protein ligase  ali follow..  30  2...................................SRAKRIMKEIQAVKDDPAAHITLEFVSEDIHHLKGTFLGPPGTPYEGGKFVVDIEVPMEYPFKPPKMQFDTKVYHPNISSTGAICLDILKNAWSPVITLKSALISLQALLQSPEPNDPQDAEVAQHYRDRESFNKTAALWTRLYAS 150
7 -84.900[O] KOG0426 Ubiquitin-protein ligase  ali follow..  36  1................................MAGTALKRLMAEYKQLTLNPPEGIVAGPMEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHERWSPVQSVEKILLSVVSMLAEPNDESGANVDASKMWRDREQFYKIAKQIVQKSLG 164
8 -82.200[O] KOG0416 Ubiquitin-protein ligase  ali follow..  27  2..................................SSPRRRIETDVMKL---LMSDYEVTLVNDNMQEFYVRFHGPSETPYSGGIWKVHVELPSEYPWKSPSIGFVNRIFHPNIDESGSVCLDVINQTWSPMFDMINIFVFLPQLLRYPNASDPLNGEAAALLREPNTYYAKVRDYIARYAN 148
9 -80.000[O] KOG0425 Ubiquitin-protein ligase  ali follow..  29  2.............................AQQQMTSSQKALMLELKSLQEEPVEGFRITLVDEDLHNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHERWNPTQNVRTILLSAISLLNEPNTFSPANVDASVMFRKWRDSKGKDKEYAEIIRK 167
10 -78.100[O] KOG0420 Ubiquitin-protein ligase  ali follow..  24  9..............EKQREQAQNATRGGASVKKQSAGELRLHKDISELNLPSSCSISFPNGKDDLMNFEVSIKPDDGYYQL---------ISPVYPHEAPKVKCKTKVYHPNIDLEGNVCLNILREDWKPVLNINTVIYGLFHLFTEPNSEDPLNHDAAAVLRNPKLFETNVRRAMTGGYV 167
11 -71.800[O] KOG0896 Ubiquitin-conjugating enzyme E2  ali follow..  23  2...........................CITTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN................. 145
12 -66.000[O] KOG0894 Ubiquitin-protein ligase  ali follow..  28  1...............................MASKGAYKRLMKEYLALQKNPVELVDAKPATENILEWHYIITGPPDTPYEGGQYHGTLIFPPDYPFKPPAIRMITPSGRFQTN--TRLCLDFHPKSWNPSWMVSTILVGLVSFMTSDEITTGGIVTSE---STRRTYAKDTKRFNIMDNP 148
13 -57.300[O] KOG0429 Ubiquitin-conjugating enzyme-related protein Ft1, involved in programmed cell death  ali follow..  16  1.................MEENQEKLEKSLKIPGNILKEQALAAEFVEVCRAPIDGIFVSPSANNKFLWFGVIFVRKG-IFGGGIFRFNIHIPLEFPDAPRVIFEQSNLFHPLICTSKELCLNSFPEGWKKELRRVLVVLQRSFYSYDVDTDKCINPEASVLYEHRDKFREIAKECVEASRS 172
14 -50.400[O] KOG0897 Predicted ubiquitin-conjugating enzyme  ali follow..  19  188.SKKDDMEVEHLATLEKLRQSQRQDYLKGSVSGSVQATDRLMKELRDIYRSDAFMYSIELVNESIYEWNIRLKSDPDSPLHSDLILLNILFKETYPFEPPFVRVVHPIISGGVLIGGAICMELLKQGWSSAYTVEAVIMQIAATLVKGKARIQFGATKALTQGQQQSFKSLVQIHEKN... 387
15 -14.800[S] KOG3270 Uncharacterized conserved protein  ali follow..  12  8...................TKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTI----------NNLTININILLPPQFPQEKPVISVYPPIRHHLMDKQGVYVTSPLVNNFTMHSDLGKIIQSLLDEFWKNPP............................... 128
16 -13.200[OU] KOG2391 Vacuolar sorting protein/ubiquitin receptor VPS23  ali follow..  17  35......................................SLIRQHLLNLISSYTSKTATFTHNDGRSVILLQADGTIPMPFQGVSYNVVIWLLESYPQYPPCVYVNPT--HSNVSPSGLVSLPYLQN-WIPSSNLVDLASHLSAAFSRDPP............................... 157
17 -9.520[S] KOG4018 Uncharacterized conserved protein, contains RWD domain  ali follow..  16  2..................................TDYGEEQRNELEALESIYPDSFTV--LSENPPSFTITVTSEAGENDETVQTTLKFTYSEKYPDEAPLYEIFSQ---ENLEDNDVSDIKLLALQAEENLGIFTLVTAVQEKLNEIVDQIKLEERRKNKRKEAEEAEKQLFH....... 140
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Jaroszewski L, Li W, Godzik A. Comparison of sequence profiles. Strategies for structural predictions using sequence information. Protein Sci. 2000 Feb;9(2):232-41.