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Query: [U] KOG0547 Translocase of outer mitochondrial membrane complex, subunit TOM70/TOM72, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAENSLLRFITKNKVAILATVSAGTAAVGAYVYYQQIKQQQQQQLKGTKDNRRQSEAFAGQNEDEADLKDDGSVVSGSNKRKKKKNKRKRNNKAKSGEGFDYPSLPNGEPDIAQLKGLSPSQRQAYAVQLKNRGNHFFTAKNFNEAIKYYQYAIELDPNEPVFYSNISACYISTGDLEKVIEFTTKALEIKPDHSKALLRRASANESLGNFTDAMFDLSVLSLNGDFDGASIEPMLERNLNKQAMKVLNENLSKDEGRGSQVLPSNTSLASFFGIFDSHLEVSSVNTSSNYDTAYALLSDALQRLYSATDEGYLVANDLLTKSTDMYHSLLSANTVDDPLRENAALALCYTGIFHFLKNNLLDAQVLLQESINLHPTPNSYIFLALTLADKENSQEFFKFFQKAVDLNPEYPPTYYHRGQMYFILQDYKNAKEDFQKAQSLNPENVYPYIQLACLLYKQGKFTESEAFFNETKLKFPTLPEVPTFFAEILTDRGDFDTAIKQYDIAKRLEEVQEKIHVGIGPLIGKATILARQSSQDPTQLDEEKFNAAIKLLTKACELDPRSEQAKIGLAQLKLQMEKIDEAIELFEDSAILARTMDEKLQATTFAEAAKIQKRLRADPIISAKMELTLARYRAKGMLLast
1 -141.000[U] KOG0547 Translocase of outer mitochondrial membrane complex, subunit TOM70/TOM72  ali  100  1MAENSLLRFITKNKVAILATVSAGTAAVGAYVYYQQIKQQQQQQLKGTKDNRRQSEAFAGQNEDEADLKDDGSVVSGSNKRKKKKNKRKRNNKAKSGEGFDYPSLPNGEPDIAQLKGLSPSQRQAYAVQLKNRGNHFFTAKNFNEAIKYYQYAIELDPNEPVFYSNISACYISTGDLEKVIEFTTKALEIKPDHSKALLRRASANESLGNFTDAMFDLSVLSLNGDFDGASIEPMLERNLNKQAMKVLNENLSKDEGRGSQVLPSNTSLASFFGIFDSHLEVSSVNTSSNYDTAYALLSDALQRLYSATDEGYLVANDLLTKSTDMYHSLLSANTVDDPLRENAALALCYTGIFHFLKNNLLDAQVLLQESINLHPTPNSYIFLALTLADKENSQEFFKFFQKAVDLNPEYPPTYYHRGQMYFILQDYKNAKEDFQKAQSLNPENVYPYIQLACLLYKQGKFTESEAFFNETKLKFPTLPEVPTFFAEILTDRGDFDTAIKQYDIAKRLEEVQEKIHVGIGPLIGKATILARQSSQDPTQLDEEKFNAAIKLLTKACELDPRSEQAKIGLAQLKLQMEKIDEAIELFEDSAILARTMDEKLQATTFAEAAKIQKRLRADPIISAKMELTLARYRAKGML 639
2 -83.400[O] KOG0548 Molecular co-chaperone STI1  ali follow..  13  1.............................................................................................................................MAEEAKAKGNAAFSSGDFTTAINHFTEAIALAPTNHVLFSNRSAAHASLHQYAEALSDAKETIKLKPYWPKGYSRLGAAHLGLNQFELAVTAYKGLDVDPTNEALKSGLADAEASVARSRAAPNPQEIQKNPSSLNLYLKDQRVMQSLGVL--------LNVKFRPPPPQGDEAEVPESDMGQSSS--NEPEVEKKREPEPEPEPEVTEEKEKKERKEKAKKEKELGNAAYKKKDFETAIQHYSTAIEIDDEISYLTNRAAVYLEMGKYNECIEDCNKAVERGRELRSDYKMVARALTRKGKMAKCSKDYEPAIEAFQK-ALTEHRNPDTLKRLNDAERAKKEWEQKQYFDPKLGDEEREKGNDFFKEQKYPEAIKHYTEAIKRNPNDHKAYSNRAASYTK----------------LGAMPEGLKDAEKCIELDPTFSKGYSRKAAVQFFLKEYDNAMETYQAGLEHDPSNQELLDGVKRCVMRQVLSDLQENPSAAQKHMQNPMVMNKIQKL 563
3 -79.700[S] KOG4648 Uncharacterized conserved protein, contains LRR repeats  ali follow..  11  1.........MTSANKAIELQLQVKQNAEEFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDSTHESLSQESESEEDGIHVDSQK----ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYEVLELEPNNFEATNELRKISQALASKENSYPK----------------------------------EADIVIKSTEGERKQIEAQQNKQQAIS--EKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDVLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSEL 621
4 -73.600[R] KOG1124 FOG: TPR repeat  ali follow..  2...............HFFFVPNSSSSSANTSSFSLSFLTPQIPENLCKSPTKIHIGTHGISGQS---FLSHPTFSSKNTYLYAVVDRSSGVFSPQKESANGEGEESNTEEGVRRPLLENSDKESSEMPIFEPERSESSSSSSAAAAARAQERPLAVNLD---LSLYKAKVLARNFRYKDAEKILEKCIAYWPEDGRPYVALGKILSKQSKLAEARILYEKGCQSTQGENSYIWQCWAVLENRLGN----RRARELFDAATVADKKHVAAWHGWANL--------EIKQGNISKARNLLAKGLKFCGR--NEYIYQTLALLEAKAGRYEQARYLFKQATICNSRSCASWLAWAQLEIQQERYPAARKLFEKAVQASPNRFAWHVWGVFEAGVGNVERGRKLLKIGHALNPRDPVLLQSLGLLEYKHSSANLARALLRRASELDPRHQPVWIAWGWMEWKEGNTTTARELYQRALSIDANTESALQAWGVLEQRAGNLSAARRLFRSSLNINSQSYVTWMTWAQLEEDQGDTERAEEASWVTGFLDIIDPALDTVKRLLNFGQN--NDNNRLTTTLRNMNRTKDSQSNQQPESSAGREDIETGSGFNLDVF--LRSKLSLDPLKLDVNLDSKRLERFTR.. 646
5 -71.800[R] KOG1129 TPR repeat-containing protein  ali follow..  4.........................................................................................................................................LSDSTYVDELENEDMGLALDQNVIAPNARPGTSFARPKTSAKGVNPILRPT-TNAGRPLSGVVRPQSSFKSGSMDQAVRTARAKTARAVSSTSARNMRLGTASMAAGA----GEFVNLARLNIDKYAADPQVNRQLFEY-------VFYYLNDIRVAHQIAGTASKAAGFE-DYYWKNQLAKCYLRLGMLQDATKQLQSSLEQ-KKLIETFALLSKAYNRVDQPMAALKTYSAGLEVFPEVTMLTGMARVQEALGEYDESVKLYKRVLDAESNNIEAIACVATTYYYGGKPELAMRYYRRILQMGVSSPELFLNIGLCCMAAQQFDFALSSILRAQSTMTDAADVWYNIGQILVDIGDLVSAARSFRIALSHDPDHSESLVNLGILKHR----------------EGKIDEARSLYSSATSKNPYMFEGNYNLGLVSFTQGKYHECRELIEKALAAFPEHEHCKKILN--HLKPLYESI....................... 458
6 -71.000[DO] KOG1174 Anaphase-promoting complex (APC), subunit 7  ali follow..  12  1.........MNVIDHVRDM---AAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHAD---SLFHDKEYRNAVSKYTMALQQKKALSKTSKV------RPSTGNSASTPQSQCLPSE----IEVKYKMAECYTMLKQDKDAIAIL-DGIPSRQRTPKINMMLANLYKKAGRERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTM--NVIQTVPNLD-----------------------------------------------LSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDLYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSR----------------EQKYEDGIALLRNALANQSD-CVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQEKEESPTDATQEEDVDDMEGSGEEGDLEGSDS.. 550
7 -70.400[DO] KOG1173 Anaphase-promoting complex (APC), Cdc16 subunit  ali follow..  30IDMRRYSTALFWAEKVAVLGPRDIYYQAQCMYLLGEYHRAAHTIQHHKLEKNSLPCFN----LLLESLYAAKEFTEAANVIQNV---EVEVMTTSLINQPVDASSGCYLESNSVFGGEENHRNELLSSIYLMKGKVYEALDNRGMAMDFYVQALHKSIYCFEALEALKLYESRLKKYYELIS--EMSPIVNPDILQFIKEFTARVQQSGSSDTQMPKVKASSLIDASHRSMFDSSSRRRSRDHDTDTL-----IPIAECLDRVQRSTDLMAAEA--------EKCFYDCDYKQCLKILNELLKVDPFHNTALTIQIACLV--ENGDFNRLFYVAHKLVDRYPDKAISWYAVGCYYDMIGKSDPARRYLSKATALDRLGPAWLAYGHSFANENEHEQAMAAYFKATQLMRGCHLPLLYIGVECGLTKNLELAEKFFLQAMNIAPLDVYVLHELGVIKYEYEFFDGAATIFQCTVDIVKQRAKLFINLGHSLRKVHKYEEALYNFQYALLLKPQSPTTYTSIGFIHAL----------------LGNLDPAIEAFHKSLALNRDCIVTSTILKSCIEDLMDDSATIDEICSAALRDVAKNITANSRRVLNSDKFNGMKLKFDEEEEFANSDSNMVVEMSFD 717
8 -68.700[T] KOG4162 Predicted calmodulin-binding protein  ali follow..  10  168.KAEKDTEMISCFERASDLGLLYLQEYSSFAISSTIPASGPSGLEMNRRMGAILETALQRAPIV---LIKTEKLQEAVERYRIMLNAIETRATQSLRLTLARQ-RGVSGTIYSPPFTGKSGGGTLRGGS-RNQQEEVILLLLIAEALAVRDTVLSQSPEFRQAYDLLTLATVRWGLVQLLNESFEKALKFSFGEQHVWRQYGLSLMAAEKHSHALRVLQ--------------------------------------ESMKLTPSDPLPCLLASRL-------CYESLETVKQGLDYAQQALKREVKGLRQQLAIQSNLKSERDACHKLALDALERAVQFDGNDHLAEYYLSLQYALLGQLAEALVHIRFALALRMEAPCLHLFALLLTSSRRPREALGVVEDALHEFPDNLQLLHVKAHLQLHLEDAETALGTVQHMLAVWRDQIEIWLLLADVYLRIDQPNEALNCIHEASQIYPLSHQIMFMRGQVHVYLEQWFDAKQCFLNAVAANPNHTEALRALGEAHLV----------------LGEPRLAEKMLKDAAKLDPSCPKIWFALGKVMEILGDFHASADCFATSLQLEPSCPVLPFTSI.................................. 856
9 -68.600[V] KOG0624 dsRNA-activated protein kinase inhibitor P58, contains TPR and DnaJ domains  ali follow..  14  7.......................................................................................................LLILWSSLFASTFAGTAEE----VAKHLELGSQFLARAQFADALTQYHAAIELDPKSYQAIYRRATTYLAMGRGKAAIVDLERVLELKPDFYGARIQRGNILLKQGELEAAEADFNVLNHDSSNNDVQEKTALIEQHRQLRHQIKSAY-----------------------------------------------------------------------AGGDCATVEEYINHIIEIQVWDASLYRMRAKCLEERGELKKAIHDMRIVSKLSTDTDTMFETSKLLYTVGDLEESLNVIRECLKLNPDHKSCYPFYKKLKVENSDWMACLEEGQKTMKFDPTPLNVFRITNRCQREAGHISEAIAECNEILNDDPSDADILCERAEAHILDEDYDSAIEDYQKATEVNPDHREAKEGLEHA------------------KRLKTQAGKRDYYKILGVKRNASKREITKAYRKLAQKWHPDNFSDEEEKKKAEKKFIDIAAAKEVLKRRQFDQGVDPLDPEAQRQGGGHHGGFGHG.. 468
10 -68.300[D] KOG1126 DNA-binding cell division cycle control protein  ali follow..  10  13IDNQNYDNSIFYSERLHAIEDSNESLYAYSHFLNLDYNIVYDLLDRVISHVPCT--------LFARTSLILGRYKQGISAVEACRSNWRSI---------------QPNINDSISSRGHPDA----SCMLDVLGTMYKKAGFLKKATDCFVEAVSINPYNFSAFQNLTAIGVPLDANNTAMKGFEKSQTNATASVPEPSFLKKSKESSSSSNKFSVSESIANSYSNSSISAFTKWFDRVDASELPGSE-----KERHQSLKLQSQSQTSKNLLAF--------NDAQKADSNNRDTSLKSHFVEPRTQALRPG-ARLTYKLREARSSKRGESTPQSFREEDNNELLKLFGKGVYLLAQYKLREALNCFQSLPIEQQNPFVLAKLGITYFELVDYEKSEEVFQKLRDLSPSRVKDMEVFSTALWHLQKSVPLSYLAHETLETNPYSPESWCILANCFSLQREHSQALKCINRAIQLDPTFEYAYTLQGHEHSANEEYEKSKTSFRKAIRVNVRHYNAWYGLGMVYLK----------------TGRNDQADFHFQRAAEINPNNSVLITCIGMIYERCKDYKKALDFYD................................................... 557
11 -67.700[DO] KOG1155 Anaphase-promoting complex (APC), Cdc23 subunit  ali follow..  10  8..RNEIRAAIRQ-DRCLYSAAKWAG---EQLVGIEQDPSNFTPANTRFQRGSSSIRRRFSTNESISTPLPSVGFSQAATPLPEEDEAIDGDIYLLAKSYFDCREYRRASHMLRDQVSKKSRKEEEMIELEGPLGKSDAINRELVSLERDLSALRRTGAIDSFGLYLYGVVLKEKGNESLARASLVESVNSYPWNWSAWSELQSLCTSIEILNSLN-----------------------------------------------LNNHWMKEFFLG--------NAYQELRMHTESLAKYEYLQGIFSFS--NYIQAQTAKAQYSLREFDQVEIMFEELLRNDPYRVEDMDLYSNVLYAKEACAALSYLAHKVFLTDKRPESCCIIGNYYSLKGQHEKAVMYFRRALKLNKKYLSAWTLMGHEYVEMKNTPAAIDAYRRAVDINPTDYRAWYGLGQAYEMMGMPFYALHYFRKSIFFLPNDSRLWIAMAKCYQQLYMLEEAIKCYKRAVNCTDTEGIALNQLAKLHQK----------------LGRNEEAAYYFEKDLERGPNMFEALVFLATHFKNHKKFEEAEVYCTRLLDYSGPEKEKAKSLRMAQTGFPSMDLEHFP................... 578
12 -65.200[O] KOG0550 Molecular chaperone (DnaJ superfamily)  ali follow..  13  2.....................................................................................................TEVETTHMNAGTESQQEPAEL----AEKQKAIGNAFYKEKKYAEAIKAYTEAIDLGSDSALAYSNRAATYMQIGEFELALCDAKQSDRIKPDVPKTQSRIRQAYEGLSILNEAEVYLKN-----------------------------------------------------------------KQAGLALNALDRLQRRIDSTTQPPMS-WMYLKAQVYIFQNDMDRAQKIAHDVLRLNPKNVEALVLRGKVMYYSGENAKAITHFQEALKLDPDCTNTKNQGNDLFRQGNYQDAYEKYSEALQIDPDNAKLYMNRATVLLRLKRPEEALSDSDNALAIDSSYLKGLKVRAKAHEALEKWEEAVRDVQSAIELDASDANLRQELRRLQLELKKSKRKDHYKILGVSKEATDIEAYRKLALVYHPLEAEARFKEVGEAYTILSD-PESRRRFDSGVDLEPGMEGGAYQAGGSFPGGGFPGGGFPGGSYNSQGFGMGGGFPGFTSFQ................................ 474
13 -65.000[B] KOG1156 N-terminal acetyltransferase  ali follow..  13  2.............................................PAVSLPPKENALFKR----ILRCYEHKQYRNGLKFCKQILSNPAEHGETLAMKGLTLNCLGKKEEAVRRGLRNDLKS----HVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEE-----------------------------------FRKTQQTSPDKVDYEYSELLLY---QNQVLREAGLYREALEHLCTYEKQICDKLAV--EETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKAL-KPANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDKFLRMNKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKA----------------NLIKEAEEMCSKFTREGTSAVENQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKL... 568
14 -61.100[A] KOG0495 HAT repeat protein  ali follow..  10  277.DINDIKKARLLLKSVRETNPNHPPAWIASARVTGKVQMARNLIMRGCEMNIQSEDLWL-------EAARLQPPDTAKAVIAQAARHIPTSVRIWIKAADLESETKAKRRVFRKALEHIPNSVRLWKAAVEDDARILLSRAVECCNTSVLNKARENIPTDRQIWTTAAKLEEANGNIHMVEKIIDRSLTSLTVNGDQWFQEAIEAEKSGAVNCCQSIVKAVIGIGVEEEDRKQTWIDDAEFCAKENAFECARAV-YAHALQIFPSKKSIWLRAAYFE--------KNHGTRESLEALLQRAVAHCPKSEILWLMGAK--SKWMAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPTPRVMMKSARLEWALEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAVLWLEAIRVELRAGLKEIASTMMARALQECPNAGELWAEAIFMETKPQRKTKSVDASKLFWSEHKFSKCRDWFNRTVKIDPDLGDAWAYFYKFELLHGTEAQQQEVLDRCISAEPTHGESWCRVS-EVLRAVVRELSIP.................... 912
15 -60.100[R] KOG1125 TPR repeat-containing protein  ali follow..  12  79..SPSIDDFLCETKSEAIARPTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSEPSSKT--------SSLKKKADGSDLISTDAEQRGQPLRVPETSSLDLDIQTQLEKWDD----------KFHGDRNTKGHPMAERKSSSSRTGSKELLWSSEHRSQPE---LSGGKSALNSESASELELVAPTQARLTKEHRWGSALLSRNHSLEE--EFERAKAAVEDTEFWDKMQAEWEEMARRNWISENQEA---------------------------------------------------------------------------QNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRRMSKSPVDSSVLEGVKELYPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANG----------------DRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPADLDVLLRAFNLDP................... 626
16 -58.600[R] KOG1128 Uncharacterized conserved protein, contains TPR repeats  ali follow..  10  179.............................VRFQFYEYDKADNLIKSASEECQLNMDLSGMMGKRHKDPSTTGTPLPPDSDIPQSLDMNDDT--LLEQVAITEQGARVDGRT------LNACQLSCLLWIARHESATHRHDVLVHERCSPVLDTVIAARRY---WSIQAAALLARAELERGVRQVDRSCTQSELVVQSSVLLAGILNSLGCTSEALLILEKLEMWDG------------------------------------------------------VIDCYKQLGQMDKAETLIRRLIEQKPNDSMLHVYL--GDITRNLEYFTKAIELS------DDRNARAHRSLGHLLLMDKKFEEAYKHLRRSLELQPILGTWFNAGYCAWKLENFKESTQCYHRCVSLQPDHFEAWNNLSAAYIRHGQKPKAWKLLQEALKYNYEHPNVWENYMLLSVDVGEFSQAIQAYHRLLDMNKRGADDEVLELIAQTLLRR--EAEISMDESEDKAQNEAENRKEKEEMIKLLARISANHQTALLKKPSVLSSETRTEFEKYVRLLEKSLAAANGKLTWPKEEKLALEVVETAVRLAEDRLELAKFIASDTSVKSAKVRLSLRGILTRLDKDSGSRVSGDETEKL 771
17 -53.700[S] KOG4340 Uncharacterized conserved protein  ali follow..  20..................................................................RLIRDARYAEAVQLLGQ---LHPELEQYRLYQAQALYKACLYPEATRVAFLL--DNPAYHSRVLRLQAAIKYSEGDLPGSRSLVEQLLSGGDNETDGQVNLGCLLYKEGQYEAACSKFSATLQASGYQPDLSYNLALAYYSSRQYASALKHIEIIERGIRQHPELGVGMTTEGFDVRSVGNTLVLHQTALVEAFNL------------------KAAIEYQLRNYEVAQETLTDMPPRAEEELDPVTLHNQALMNMD-ARPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKPYLYDFLDALITCQTAPEEAFIKLDGLAGMLTEQLRRLVQEARHNRDDEAIKKAVNEYDETM---EKYIPVLMAQAKIYWNLENYPMVEKVFRKSVEFCNDHDVWKLNVAHVLFQENKYKEAIGFYEPIVKKHYDNAIVLANLCVSY----------------IMTSQNEEAEELMRKIEKEEYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYNKKHDSVIQECVQFLGHCELYGTNIPAVIEQPLEEERMHVGKNTV 609
18 -52.900[U] COG5010 Flp pilus assembly protein TadD, contains TPR repeats  ali follow..  11  1.................................................................................................................................................................................................................................................................................................................................................MTMQDNFSFSLRRATGVAVAMVALSLSACAGQQGRKELTTGSPKLTRPVQSMNATELAAAAERIGQAYERNPKDREAGLNYANLLRMTGRNEQALAVMQQVAIYHPADREVLGAYGKAQAAAGQLEQALATISRAQTPDRPDWKLKSAEGAILDQLGRSAEARLRYREALDLKPNEPSVLSNLGMSY----------------LLTKDLRTAETYLKSAASQPDAGSSVRQNLALAVGLQGRFQEAETIAGQELTSEQAEANVAYLRSLSQQGAWKQLAKAD.................... 269
19 -51.700[R] COG4785 Lipoprotein NlpI, contains TPR repeats  ali follow..  2..................................................................................................................................................................................................................................................................................................................................KPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVILARMEQILASRERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDEKQAKEQHFEKSDKEQWGWNIVEFYLGNI-----------------SEQTLMERLKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALLSLLGQDQDDLAESDQ.................. 293
20 -50.900[S] KOG3060 Uncharacterized conserved protein  ali follow..  12  6..................................................................................................................................................................................................................................................................................................................................EKMSWSDVRDQFRTWREETGRHSEEVVQLWVAVLE-----------DKVHKTGNERLILEQVIIAALDTARFDIATKCTKQLSLEFPGSLRVMKFKAMRYEALEQYDEADEVLDAIIAKDETNAAPRKRKIAILKARGRRLEAIKELNEYLKKFMSDQEAWHELCNMYLAEGEFGKAAFCMEEVLLHNPHSHLIHQRLAEIRYTMG-------------GVENMESARTYYSQALKLNPHNLRALYGIYLCCNHLDNSRAVSSKRKELQKLSQWALEQLLTKQIVPLEAAFGNLEIKSN.................. 282
21 -50.500[R] KOG0553 TPR repeat-containing protein  ali follow..  14  6......................................................................................................................................................RLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTEIFEAAATGKEMPQDLRS---------------------------------------------------------------------------------------------------------------PARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPAAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQN------------------------DLASLIQAGQQFAQQMQQNPELIEQLRSQIRSRTPSASNDDQQE...................................................... 313
22 -50.000[Z] KOG1840 Kinesin light chain  ali follow..  12  1MEGGSVNESHSNADQMFDTT---IEELCKNLCELQSSNQSPSRQSFGSYIDSDLQHLALGEMRDIDILEDEGDEDEVAKPEEFDVKSNSSNPRDMEKQTGKKNVTKSNVGVRKKKVGGSSENVELARFLLNQARNLVSSGDSTHKALELTHRAAKLCLEWIMCLHVTAAVHCKLKEYNEAIPVLQRSVEIPVV-FAGLMQLGDTYAMVGQLESSISCYT------------------------------EGLNIQKKVLGENDPRVGETCRYLA--------EALVQALRFDEAQQVCETALSIHRESAEAADRRLMGLICETKGDHENALEHLVLASMAESEVAFVDTSIGDSYLSLSRFDEAICAYQKSLTALKTGSVYIRLADLYNRTGKVREAKSYCENALRIYESHASGLTDISVICESMNEVEQAITLLQKALKIKIMIAGIEAQMGVLYYMMGKYMESYNTFKSAISKSTFFGIALNQMGLACIQLDAIEEAVELFEEAKCIHPETLGLYSNLAGAYDA----------------IGRLDDAIKLLGHVVGVNPVTEDEKRRLAQLLKEAGNVTGRKAKSLKTLIDSDL........................................... 643
23 -49.500[NU] COG3063 Tfp pilus assembly protein PilF  ali follow..  12  4..........................................................................................................................................................................................................................................................................................................................................................KPSKRISLLLVLALGACSTSYRPSRAEKANQSNIKTQLAMEYMRGQDYRQATASIEDALKSDPKNELAWLVRAEIYQYLKVNDKAQESFRQALSIKPDSAEINNNYGWFLCRLNRPAESMAYFDKALATYPTPYIANLNKGICSAKQGQFGLAEAYLKRSLAAQPQFPPAFKELARTK----------------MLAGQLGDADYYFKKYQSRVEVLQADDLLLGWKIAKALGNAQAAYEYEAQLQANPYSEELQTVLT.................................. 251
24 -47.200[G] COG2956 Predicted N-acetylglucosaminyl transferase  ali follow..  10  3................................................................................................................................ELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVNFLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLT----------------------------------------------------------------------------------------------------------------YEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFIGALQQLLQIYQATSEWQKAIDVAERLVKLGKDKAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSIMMGRVFMAKGEYAKAVESLQRVISQDRELSETLEMLQTCYQQLGKTAEWAEFLQRAVEENTG-ADAELMLADIIEA----------------RDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLAEEGRAKESLMVLRDMVGEKVRSKPRYRCQKCGFTAY............................ 365
25 -45.900[OT] KOG1308 Hsp70-interacting protein Hip/Transient component of progesterone receptor complexes and an Hsp70-binding protein  ali follow..  10  2..DPCKVNELRAFVKMCKQDPSVLHT---------EEMRFLREWVESMGGKVPPATQKAKSEE---NTKEEKPDSKKVEEDLKADEPSTEESDLEIDKEGVIEPDTDAPQEMDENVEITEEMMDQ-ANDKKVAAIEVLNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIQDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLAACKLDYDEDASAMLKEVQPR----------------------------------------------------------------------------------------AQKIAEHWRKYERKHEEREIKERIERVKKAQEEQERAQREEEARRQSGAH-YGPFPGGFPGGMPGNFPGGMPGMGGDMPGMAGMPGLNEILSDPEALAAMQDPEVMVAFQDVAQNPANMSKYQSNPKVMNLISKLSAKFGGQA......................................................................................................................................................................... 369
26 -44.200[T] KOG1130 Predicted G-alpha GTPase interaction protein, contains GoLoco domain  ali follow..  3..............................................................................EDHSFHVRYRMESCLELALEGERLCKSGDCRAGFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDIKVGEARALYNLGNVYHAKGKSFGCPGPQDVG------------------------------------------------------------EFPEEVRDALQAAVDFYEENLSLVTAAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDACWSLGNAYTALGNHDQAMHFAEKHLEIKSGELTARLNLSDLQMVLGSYSTNNSIMSENTEIDSSKLGRRHSMENMELMKLTPEKVQNWNSEILAKKPSAKLLFVNRLKGKSQRKISADTIGDEGFFDLLSRFQSNRMDDQRCCLQETASTTTSSTPPKMMLKTSSVPVVSPNTDEFLDLLAS........................................... 546
27 -43.300[S] KOG4507 Uncharacterized conserved protein, contains TPR repeats  ali follow..  11  203....................................................................RLGRSIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKNEPYQVAMRALHFSSRHNKDIA--LVNLANVLHRAHFSADAAVVVHAALDD-SDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILQICRLVNQQHSLHCRWDQPVRYHRGDIFENVDYVQFGEDS-RMDLKAKMPDDHARKILLSRINNYTIPEEEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQ-PLVNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTTKCPECENSLKLIRCMQ------FYPFLYNITSSVCSGNCHEKTLDNSRDKQKYFDNSQSLDAA-EEEPSERGTEEDPVFSVENSGRDSDALRLESALVDEFQQAWPLEGFGGALEMKGR-PKGDHKKTPGKKVETGQIENGHRYQANLEITPKVAS........................................ 941
28 -40.100[S] KOG4555 TPR repeat-containing protein  ali follow..  12  1...................................................................................................................................................................................................................................................................................................................................MPQANLTLSPHDQQ--VLDSIFNPLELSSLQTNNLIPAESDLKDEEPDTQAIKASRELELKAIALSESGELDGALELFQQSLNL-AQRASVLNNRAQTLRLAKRDEEALDDLNKALELANDQCHAHCQRGVLYRKLDNLEAARADFEAAAQLGSKFAREQLVEINPYAALCNLRQAFDQLK....................................................................................................................................... 185
29 -40.000[O] COG4235 Cytochrome c biogenesis factor  ali follow..  13  1..................................................................................................................................................................................................................................................................................................................................................................................................VPEAFPEQSVPEGKRAGYVVYLPGIVVALIVAGVSYYQTGNYQ-QVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKNPGDIEGWIMLGRVGMALGNASIATDAYATAYRLDPKNSDAALGYAEALTRSS-------------DPNDNRLGGELLRQLVRTDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIE-RSIAQAMQHLSPQES.................. 220
30 -39.800[D] KOG1915 Cell cycle control protein (crooked neck)  ali follow..  13.YMTRKDAELKLPRMTQVKNKTPAPIQITAEQILRERLRRRKEFEDQIRRARLNTQVWVKYADFE---MKNKSVNEARNVWDRAVSLLPRVDQLWYKFIHMEEKLGNIAGALERWIHCSPDQQ-----AWLCFIKFELKYNEIECARSIYERFVLCHPK-VSAYIRYAKFEMKHGQVELAMKVFERAKKELADDEEAEILFVAFAEFEEQYKFALDQIPK-GRAENLYSKFVAFEKQNGDKEGIEDAIIGKRRCQYEDEVRKNPLNYDSWFDFVRLE--------ETVGNKDRIREIYERAVANVPPPEAQEKRYWQRYIY--------------------------INYAFFAEMVTEDVESTRDVYRACLKLIPHSKIWLLAAQHEIRQLNLTGARQILGNAIGKAPKD-KIFKKYIEIELQLRNIDRCRKLYERYLEWSPGNCYAWRKYAEFEMSLAETERTRAIFELAISQPALDELLWKTYIDFEISEGELERTRALYERLLDRTKHCKVWVDFAKFEASAAEHKEDEEEEDAIERKKDGIKRAREIFDRANTYNKDSTPELEDWLNMETGFGKLGDVRVVQSKLPKKVKKRKLSSREDGCTEYEEYTDYLFPEESETTSLKILEAAHK..... 645
31 -39.200[U] KOG2376 Signal recognition particle, subunit Srp72  ali follow..  13  2...........................................................................................................APKSKENPKTSTPA-----IEDLFTSLHKHIKDTKYEEAVKVADQVLSIVPTDEDAIRCKVVALIKDDKFDDYLIKDVKINGINSFPIDLGFHKAYCLYRENKLDEALVCLKGLERESK--------------------------------------------------TLLLEAQILNCLGKVDACVDVYQKLNKSGIKLIEVNLVAALIRAGKASQVLESLKIR-------PTTTYQLAYNTACSLIENSNYVDAEQLLLTAMRIGQETPISVQLAYVQQVLGQTQESKSSYVDIIKRNLADESIYANRVLLLLHANKMDQARELCATLPGMFPESVIPTLLQAAVLVRENKAAKAEELLGQCAENFPEKSLVLLARAQIAASASHPHVAAESLSKIPDIQHLPATV----------ATIVALRERAGDNDGATAVLDSAIRWWSDSMTDSNMLRILMPVAAAFKLRHGQEEEASRLYEEIVKNHNSTDALVGLVTTLARVNVEKA........................ 510
32 -38.700[U] KOG3081 Vesicle coat complex COPI, epsilon subunit  ali follow..  12  1.........................................................................................................................................................MSAMGAGPDHLFNLRNNFY-LGAYQTAINNSEIANLSPENAVERDCLVFRSYIALGSYQLVISEID-----------------------------------------------------------------------------------------------------------------------ESAATPLQAVKLLAMYLSTPQNKESTISSLKEWLADSTNDTLRLIAGIIFMHEEDYNETLKHTHA-----GGTMDLYALNVQIFIKMHRAEYAEKQLRVMQQIDEDHTLTQLASAWLNLAVGKIQEAYLIFEDFSEKYPMTCLILNGKAVCCMQMGNFDEAETLLLEALNKDAKDPETLANLVVCSLHVG------------------KSSSRHLSQLKLSHPEHI-----VKRVSSAEDNFERAVQLVA................................................... 293
33 -35.800[S] KOG2796 Uncharacterized conserved protein  ali follow..  10  5...........................................................................................................................................LGEKAAAKRQVLNADSVEQSFVGLKQ-VDLCGRLLTAHGQGYGKSGLLTSHTTDSLQLWFVRLALLVKLGLFQNAEMEFEPF-------------------------------------------------------------------GNLDQPDLYYEYYPHVYPGRRGSMVPFSMRIL------------------------------HAELQQYLGNPQESLDRLHKVKTVCSKILANLEQGLAEDGGMSSVTQEGRQASIRLWRSRLGRVMYSMANCLLLMKDYVLAVDAYHSVIKYYPEQPQLLSGIGRISLQIGDIKTAEKYFQDVEKVTQKKIMVLMNSAFLHLGQNNFAEAHRFFTEILRMDPRNAVANNNAAVCL----------------LYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLLESSRSMQKKQALLEAVAGKEGDSFNTQCLK................................... 377
34 -35.800[A] KOG2047 mRNA splicing factor  ali follow..  5.KDLYPSQEDLLYEEELLRNQFSLKLWWRIAKAESPFKKRFIIYERALKALPGSYKLWYAY-IVRNLPVTHPQYDSLNNTFERGLVTMHKMPRIYLQTLTVQQLITRTRRTFDRALCALPVTQEPYLVFVSQNG------IPIETSLRVYRRYLMYDPSHIEEFIE---FLVKSERWQESAERLASVLNFTDEVGMLWTSLADYYIRKNLLEKARDIYEEGMMKVVTVRDFSVIFDVYSRFEESTVAKKMEMMSSSDEEDENEEEELMNRRPALANSVLLRQNPHNFEGNAAKQILTYTEAVRTVDPMKAAKLYENHKDLVNTRVIFDKAVQVNYKTV---DHLASVWCEWAEMELRHKNFKGALELMRRATAVPTVERLWSFYVDLEESLGTLESTRAVYEKILDLRIATPQIIMNYAFLLEENKYFEDAFKVYERGVKIFKY--VTYLTKFVKRYGKTKLERARELFEHAVSMAPAVRTLYLQYAKLEEDYGLAKRAMKVYEEATKKVPEGQKLEMYEIYI--------------SRAAEIFGVPRTREIYEQAIESGLPHKDVCIKFAELERSLGEIDRARALYKYSSQFNEDTYREMLRIKRSVSASYSQTHFILPENMMQKDKLLDVEDAKGEL 793
35 -35.000[O] KOG4642 Chaperone-dependent E3 ubiquitin protein ligase (contains TPR repeats)  ali follow..  13  1.....................................................................................................MKGKEEKEGGARLGAGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQES--------------ELHSYLSRLIAAERERELEECQRNHEGDEDDSHVRAQQA--CIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEE-----------HLQRVGHFDPVTRSPLTQEQLIPNLA---------------MKEVIDAF---ISENG.................................................................................................................................................................................................... 298
36 -34.900[O] COG5536 Protein prenyltransferase, alpha subunit  ali follow..  10  1.................................................................................................................................................................................................................................................................................................................................................MDPIDPELNEILDFTEYGPLTPIPQDDGENPLAKICYTTGYQGMAYFRAIMAKKEYSLRALNLTGFLIMNNPAHYTVWAYRFQILNHTPSIDNELEWLDEIAEDFQKNYQVWHHRQKILSLTKNYERELEFTKKMFEIDSKNYHVWSYRVWILQNFNDYSQELKLTNELLEKDIYNNSAWNHRFYVLFETS-----------KVVSWSLEEELNYLKDKILFAPDNQSAWNYLCGVLDKSGKLDNLIANLRKNLPALHKPLLEFLAMYEPSSSE-KLANEVDVPHAALWTWMSQRSN..... 293
37 -34.700[O] KOG0530 Protein farnesyltransferase, alpha subunit/protein geranylgeranyltransferase type I, alpha subunit  ali follow..  10  2.......................................................................................................................SDSDIPSSTLYKDNVDWKDITPIYPSKEEEVAVKIAVTEDFTDAFAYFRAILIKNEKSDRVMALLEDCIRLNPANYTVWQYRRVCLTELGW-----------------------------------------------------------------------------------------------------------------------------------------------------DLKKEMRYLSDIIQESPKYQVWHHRRFIVETIGEVNDELHFCSEVIRDENKNYHAWQHRQWVVRTFKVPLEKELTFLHMLLLDNRNNSAYNYRYFLMTLYDKLDIEINLAKKFIENIPNNESAWNYLAGLLNGVTSNSDVVSFVEDLYETTPEEKRSPFLLAFIADMMLE-----NIENQKSAEESAGRAKKLYKDLQSIDPVRVNYYRHQSLLAQTMLIKAQTKVTAK................................................... 328
38 -34.300[O] KOG3696 Aspartyl beta-hydroxylase  ali follow..  2..............................................AQRKNAKSSGNSSSSGSGSGSTSAGSSSPGARRETKHGGHKNGRKG-VWTSVAVVWFDLVDYEEVLGKL-------------------GIYDADGDGDFDVDDAKVLLGLKERST-----SEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETE-------------HSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPENRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKRG-------KIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAELRGAIETYQEVASLPDVLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLL----------------IGDNDNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDD....................................... 524
39 -33.600[R] COG0457 FOG: TPR repeat  ali follow..  13  371....................................NRELFKILVEKFNTG-YPATSFSELHSFSFMDVDDKGKCSMHQLMRKSLEVHNFMLDFYSNQLKDIDITPEHEIALTEAFYHAKLEAEDLLKWFISVSDPFNRAAFWQLITPMYEEMLQIHKDIVTTLNILDVLYYKMGEYKKALQFSERALAIHPDVATSLDNLAGLYESMGNYKQALQLSE-------------------------------------------------------------------------RALEIYEKVL------------------------------------PQHRDVAITLDNLAGLYESMGEYEKALIFYQRTIEIKEKATSLDNLAVLYRQMGEYEKALQLSQRALEIHPDIATTLNNIALLYDSMGDYQKTLPLYQRALEIYLGIATTLNNLAGFYRRVGDYEKALSLSQRSLEIHPDVARTLNSLALIYENIGDYEKALAFYQRSLDIHPDVGRTLNNLARLYEI----------------MGDHEKALTLYQRTIEIHPDVATILNNLAGLHYRIGEYKKALPLYQRALDIV------------------EKKLQNQPNSVVIKNNYNRLLSKMSEN 911
40 -31.300[S] COG4700 Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats  ali follow..  17  55..........................................................................................................................................................................................................................................................................................................................................................HGHTLLMRLQDKLNPERHLRKLTEELAIAETNQNHYALANELARLGRYHEAVPHYQQALSGIFHEAAMMLSLAQAQFAIQEFAACQQTLEDVMRYNPDFADGHLLFARTLAAQEKYADAESEFEVLISYYPG-PQARIYYAEMLAKMSRLREANEQYVAVVDTAKRSRPHYRKHHREWIKTA............................................................................................................... 238
41 -30.600[S] COG3898 Uncharacterized membrane-bound protein  ali follow..  10  96..............................................................................................................................................................................................................................................................................................GAGDGALARKKTKEAAKLIRSDQEPLIHLLEAQASLLEGDHEGARQKFESMLDDPEMRLLGLRGLYLEAERLGDRNAARHYAGRAAAVAPQLAAAESTLEELTARGDWDGALKLVDAQKSTRQIERDAANRRRAVLLTASDPNAARTAALEANKLQPDFAPAAVAAAAALFKQNDVRKGSKILETAWRAEPHPEIAELYTH--ARPGDAVLDRLNRAKKLQEMKKNHAESSMTVARAA----------------LDAQDFSTARSEAEAAIRMDRREGAYLLLADIEEAETGDQGKVRQLLSKAVRAPRD........................................... 395
42 -30.600[R] KOG4234 TPR repeat-containing protein  ali follow..  31  95....................................................................................................................GSNKEKALAEANEAKAEGNKLFVNGLYEEALSKYAFALELVQELSICYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHFEDAVTDLKILELDPSNDQARKGIRRLEPLAAEKREKMKEEAITKLKE............................................................................................................................................................................................................................................................................................................................................................................................. 244
43 -30.500[O] COG3914 Predicted O-linked N-acetylglucosamine transferase, SPINDLY family  ali follow..  11  2..............................................................................................................................................................................................................................................................................................................................................................PQDVMTANHVSPSNDAAAPSALDLARNLMDLLSVSEALNAAGQQAAAAELYKTWVAFNPTIHLAYFNYAVMLNQLGDRAGAVQAFRACLKANPEFAPGHINLGRALEDAGLIGHAVEQWSHYAEVTKNVHMTLQNMGRVLEGAGKLEEAETALLQAFELRPELPEAGQHWASLRQR----------------QCKWPVLAPSNHISPRKMLDAMSSLTLSCYADDPMFQLAKAYRLSKTLIGARPDLSRF-PRRSPKQKSGTGQRLRV---LSSDLRDHAVGFALCEVL 287
44 -30.100[S] COG1747 Uncharacterized N-terminal domain of the transcription elongation factor GreA  ali follow..  12  2....................................................................................................................................................DTRDLTAYSAEKFKELDRIIAEAKRQSILDVLKGICDEHLAHSKNSIIALYISGIISLSKQLLDDSC---------------------------------------------------------------VTLLTIFGDNHKNQIVEHLCTRVLEY-------------------------------------GESKLALRALGECYKTSGN-EQLYDVWERLVRIDYEAEITRVLADKYEQEGNKEKATEFYKKALY--------------RFIARRQNAAIKEVWTKLVALIPDDVEFFYREQKKISEKLGEGRGSVLMQD--------------VYVYYKENEDWTTCINILKHILEHDEKDVWARKEIIENFRCKSQLEEYLKISNISQSWRNVFEAINDFEKHISFDEGSFVFHRTWGVGRIAKVCNDELLIDFAKRRAHTMLLKMAISALSVLKRQDLAAKIRQDP................... 362
45 -27.500[DO] KOG4322 Anaphase-promoting complex (APC), subunit 5  ali follow..  11  146LSFSQVFKLYTALQQ-----------------YFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLN----NLRVQDVFSSTHSFDRLILTGAESKSAALNLAALHCRFGHYQQAELALQEAIRI-----------AQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAF---AGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRST----MALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCMNDGKYHLADSLVTGITALNS--IEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYSETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNY-ERIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPS........................................ 746
46 -25.000[R] COG4976 Predicted methyltransferase (contains TPR repeat)  ali follow..  2...............................................................................................................................................................................................................................................................................................................................................................................TFNQLSSGDLADRRADYAKMLAEAGDAPGAAELMAQALELAPDWAAGWFRLADYEEKSGRIEAAVDALRNTLRLNPEDIFGASLKLALLGATETPEQPPSVYVERL-AERFDHALVEKLGYSVPEKLAAVIGRVNGGGRFRHVTDLGCGTGLFGERIRDRADFLEGFDLSANMLAKADLSLAPEDSGVFGALEQRRADLVSAAD-VLMYLGNLEGVFVIADRLLA............................................... 241
47 -24.900[H] COG3071 Uncharacterized enzyme of heme biosynthesis  ali follow..  10  80..................................................................................................................................................................................................................................................................................................................KRTRARNQMKAALIKLAEGDFLQVEKLLTRNADHAEQPMVNYLLAAEAAQQRGDEFRTNQYLERAAEVADGDQVNITRVRIQLAQGHIHAARHGVDRLLDQAPRHPEVLRLAEQAYLRSGAYRSLLDILPAMSKTQI-EQQAYIGIMNQCMADEGSEGLKRWWKDQSRKVRNEIPLQVALAEHLIECDDHDVAQKIILDSLKHQYDERLALL--------------------PRLKAGNPEPLEKSLRQQIKQHGATPLLNSTLGQLMLKHGEWEKASEAFKAALAQRPD-GYDYAWLALDKLHRPEDAAQARREGLLLTLRQNGESSALTKL 404
48 -23.900[S] KOG4814 Uncharacterized conserved protein  ali follow..  48......EMAVNLWNWALTIGGGWLVNEEQKIRLHYVACKLLSMCEASFASEQSIQRLIMMNMRIGKEWLDAGNFLIADECFQAAVASLEQLYVKLIQRSSPEADLTMEKITVESDH----------FRVLSYQAESAVAQGDFQRASMCVLQCKDMLMRLHHLCYNFGVETQKNNKYEESSFWLSQSYDIGKM-AKVLRLLATNYLDWDDTKYYDKALNAVNLANKEHLSSPGLFLKMKILLKGETSNEELLEA------------------------------VMEILHLDMPLDFCLNIAKLLMDHERE------SVGFHFLTIIHERFKSSENIGKVLILHTDMLLQRKEELLAKEKIEEIFLAHQTGRQLTAESMNLWRQAASSFEVQNYTDALQWYYYSLRFDLDFTKLQRNMACCYLNLQQLDKAKEAVAEAERHDPRNVFTQFYIFKIAVIEGNSERALQAIITLENILTDEEMLLSLAAQFALENGQQIVAEKALEYLAQHSEDQEQVLTAVKCLLR---LLPKIAEMPESEDKKKEMDRLLTCLNRAFVKLSQPFGE--EALSLESRANEAQ-RKTAWNLAVQCDKD........................................... 629
49 -23.500[O] KOG0551 Hsp90 co-chaperone CNS1 (contains TPR repeats)  ali follow..  14  2...................................EQPGQDPTSDDVMDSFLEKFQSQPYRGG-----FHEDQWEKEFEKVPLFMSRAPSEID---------PRENPDLACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADAVLYTNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDGLQIDAKEKKLLEMRAKADKLKRIEQRDVRKANLKEKKE............................................................................................................................................................................................................................................................................................................................................................................................. 215
50 -23.400[MOT] KOG1550 Extracellular protein SEL-1 and related proteins  ali follow..  11  257..DQEVIQSLQWMLMKLDDDEDKIQINYGDDEEYGGGGSTMRILSYGIVILSLLVFSFIEFGVHARPVVLVLSNDDLNSGGDDNGVGE---SDFDEFGESEPKSEEELDPGSWRSIFEPDDSTVQAASPQYYSGLKKINFRLMEEAVDEIEAASSA--GDPHAQSIMGFVYGI-KSKSKSFLHHNFAAA---GNMQSKMALAFTYLRQDMHDKAVQLYAEL---------------AETAVNSFLISKDSPVVEPTRIHSGTEENKGALRKSRGEEDEDFQILEYQAQKGNANAMYKIGLFYYFGLRGLRRDHTKALHWFLKAVDK----------------GEPRSMELLGEIYARERNYTKALEWLTLAAKEG-LYSAFNGIGYLYVDKKNYTKAREYFEKAVDNE--DPSGHYNLGVLYLK-RDVRQATKYFFVAAN---GQPKAFYQLAKMFHTKKNLEMATSFYKLVAER--GPWSSLSRWALEAYLKGDVGKALILYSRMAEM--GYEVAQSNAAWILDKYGERSMCMGVSGFCTDKERHERAHSLWWRA--SEQGNEHAALLIGDAYYYERDFVRAAEAYMHAKS--QSNAQAMFNLGYMHEH---QGLPFDLHLAKRYYDESLQSDAAARL 873
51 -22.400[R] COG4105 DNA uptake lipoprotein  ali follow..  10  50........................................................................................................................................................................................................................................................................................................................................................................................PADVLYNQGLANLNAGRLDEASKKFDAVDRQHPYSRKSMVMGAFADYRKGSYDEAISSAKRYLALYPSTPYAQYIIGLSYYRQKEARQTLQTMQDLVTRWPTSAGKEMQIGRYYLERREYIAAVKRFRTVVENYSNTRHV--------------EALARLTESYYAMGLTSEAQTAAAVLGTNYPDSKDSYKLLQSNGLSPRENAGSWSKAGKLIT............................................... 287
52 -22.400[U] KOG1586 Protein required for fusion of vesicles in vesicular transport, alpha-SNAP  ali follow..  10  1.........................................................................................................................................................................................................................................................................................................................MDNSGKEAEAMALLAEAERKVKNSQSF-EEACEIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGDPQEAINCLMRAIEIYTDMAKHHISIAEIYTELVDIEKAIAHYEQSADYNSSANKCLLKVAGYAALLEQYQKAIDIYEQVGTNAMDTAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSD---------SRECKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTM----------LLRIKKTIQGDEEDLR............................................... 295
53 -22.000[ODR] KOG4151 Myosin assembly protein/sexual cycle protein and related proteins  ali follow..  15  2........................................................................................................................VARVQTAEEIRDEGNAAVKDQDYIKADELYTEALQLTTDEPVLYRNRAMARLKRDDFEGAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDAKALRLSPN------------------DKGIVEVLQRLVKANNDKIKQTTSLANKVTDMEKLAFRGEAKDTEQKMTALNNLLVLCRESESGATGVWNQGVPFVLNLINDASENEEVTVTAIRILDETIKNSVRCMKFLAMHDPDGPKSVRFVCRLMCKKSTKDFVDATGILVQ--RVFNAMAKMDRQKEMKPDPEVAEANKIWIIRVLLELQEMLQDPKVGAVQRETCIDLFLKNLMHMDGGIPRGWSWKFVEE........................................................................................................................................................................ 340
54 -21.900[R] COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion  ali follow..  12  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................KKTDTLPATLSALIQEYSIAEGIQMAEQQVRENPAKALCRHSLFQLLCVAGDWSRALHQLQLCARMEANYTQEARLYRELV-----------------RCEMFRHTVFQGEQRPGFLLPQPVWVESLLAALACHDDTGEVDKHRNTALEAITDTGGQWNGGAFDWASDSDSRL....................... 157
55 -21.500[R] KOG2396 HAT (Half-A-TPR) repeat-containing protein  ali follow..  10  1MAQYRLERMVDELDDLERRE------------EIAEIVKQRRKFEYRLKRPSPLKEDFIAYIDYEVKLDELRQLRRKSVARVTKKRKKKSVSD--------FAGVARIVEIYRLATMRYKGDINLWFRYLE-----FCKQKRHGRMKKALAQAIRFHPKVAGVWIYAAS-FDRNLNVTAARALMLNGLRVCSNSEDLWVEYLRMELTFLNKLKARKVALGEDKGSLVRDTKTVEDEQWKDENKELFMSLDEKEGNEKEENDEDSIVEDVEDVTEKVDFLKEKGSNVLQTIYSGAVEAIPSSFDLRKRFLEILEATDLAHSDEMRNTLSDLKRDFCNEPEYRHEMSGCISNEAGLEFANPQMQKAIQVFEEGLQTVTSSSMFEIYINFLMENPIISHIINVYQKADETGCLTEELADEYVSLYLKLEKTHEAQKLAEKLCEKFAGSAKLWLSRVSIEIRSADFQTVFELLSNALRKVPISFSLASTVVKFVLETKGAHSARKIYKRFLALPGPSLVLYKGCIEIETNLISVG----------DKDGLSNARKLYDSAVASYGQDVELWKNYYSLETKLGTSETANGVYWRARKTLNESAD........................................ 645
56 -21.200[M] KOG3364 Membrane protein involved in organellar division  ali follow..  11  1...................................................................................................................................................................................................................................................................................................................................................MTKVDFWPTLKDAYEPLYPQQLEILRQQVVSEGGPTATIQSRFNYAWGLIKSTDERLGVKILTDIYKEAESRRECLYYLTIGCYKLGEYSMAKRYVDTLFEHERNNKQVGALKSMVEDKIQK.................................................................................................................................................................................. 126
57 -21.100[R] KOG0376 Serine-threonine phosphatase 2A, catalytic subunit  ali follow..  15  3............................................................................................................................KEALELKNEANKFLKEGHIVQAIDLYTKAIELDSTNAILYSNRSLAHLKSEDYGLAINDASKAIECDPEYAKAYFRRATAHIAIFQPKEAVGDFRKALALAPSDPAARKKLRECEQLVKRIRFQEAIHNTEPPSPLANINIE--------------DMDIPSDYDGVILEKQITKEFVEDMKERFCQGKKLPLKFAYSILRDLKELLEKTPSLIDIPVKGDETLVICGDTH---GQYFDLLNIFKLH--PPSPTNKYLFNG--FVDRGSWSTEVAFTLYAYKLLPD--AVFINRGNMNKVYGFEGECRSKYNERT---------------------------NIFSETFSLLP-SDSYLVVHGGLFSDDNVTLDQLRNIDRFSKKQPGQSGLMMEMGLQFGP-DVSKRFCEANGLKAVIRSHEVRDQGYEYCITV-PNYCDSTGNLGAVIKVKEDMELDFHQFEAV................................................. 455
58 -20.300[A] KOG1258 mRNA processing protein  ali follow..  9.......................................................................................................AEETEWDKYNRQINKNPDDFDRASEHLEGGVGRNSSKQAINTLRSVYDRFLGKYPLLFGYWKKYADFEFFVAGAEASEHIYERGIAGIPHSVDLWTNYCAFKMETNGFMQGANMVGLDFLSHPFWDKYLEFEERQERPDNVFQLLERLIHIPLHQYARYFERFVQVSQSQPIQQLLPPDVLASIRADVTREPAKVVSAGSKQITVERGELEIEREMRARIYNIHLQIFQKVQLETAKRWTFE----------------SEIKRPYFHVKELDEQLVNWRKYLDFEEVEGDFQRICHLYERCLITCALYDEFWFRYARWMSAQDHLNDVSIIYERASCISISRPGIRVQYALFEESQGNIASAKAIYQSILTQLPGNLEAVLGWVGLERRNAPLTNAHAVLRSIINEGKCNTGITEVLITEDIK------------VWKIEGDIELARNMFLQNAPALLDCRHFWISFLRFELEQPLNSKNYTEMEMIRNKTRLPPRTIMDLTKLYM-EYLCHQSNDPSVLQEYLLIDRDVFGP... 542
59 -20.200[O] KOG0543 FKBP-type peptidyl-prolyl cis-trans isomerase  ali follow..  17  226................................................................................................................KESWEMISEEKLEQNTVVKEQGSVYFKEGKYKQALLQSQKAQAP----LASHLDLAMCQLKLQAFSAAIESCNKALELDSNNEKGPFRRGEAHLAVNDFELAWADFQVLQLYPNNKAARAQLAVCQQRIHRQLARKK...................................................................................................................................................................................................................................................................................................................................................................................................... 360
60 -19.900[A] COG5107 Pre-mRNA 3`-end processing (cleavage and polyadenylation) factor  ali follow..  2........................................................................................................................SSSTTPDLLYPSADKVAEPSDNIHGDELRLRERIKDNPTNILSYFQLIQYLETQESYAKVREVYEQFHNTFPFYSPAWTLQLKGELARDEFETGKLENNDLSLWSTYLDYIRRKNNLITGGQEARAVIVKAFQLVMQKCIFEPKSSSFWNEYLNFLEQWKPFNKWEEQQRIDMLREFYKKMLCVPFDNLEKMWLTARKFIGELSAEYMKARSLYQEWLNVTNGLKRASPIN--QPGTSDSNIQQLQIWLNWIKWEREN------KLMLSEDMLSQRISYVYKQGIQYMIFSAEMWYDYSM----ISENSDRQNILYTALLANPDSPSLTFKLSECYELDNDSESVSNCFDKCTQTLLSQYKVFCVYMNTMKRISGLSAARTVFGKCRKLKRILTHDVYVENAYL--------------EFQNQNDYKTAFKVLELGLKYFQNDGVYINKYLDFLIFLNKDSQIKTLFETSVEKVQDLTQL-----YKKMISYESKFGNLNNVYSLEKRFFERFPQENLI 556
61 -18.200[R] KOG3807 Predicted membrane protein ST7 (tumor suppressor in humans)  ali follow..  10  8..............................................................................................................................................................................GEAAAVGASPASVPGLNPT-------LG--------WRERLRA-----LAGTGASLWFVAGLGLLYALRIPLRLCENLAAVTVFLNSLTPKFYVALTGTSSLISGLIFIFEWWYFHKHGTSFIEQVSVSHLQPLMGGTESSISEPGSPSRNRENETSRQNLSECKVWRNPLNLFRGAEYRRYTWVTGKEPLTYYDMNLSAQDFLRPSDTVMQKAWRERNPPARIKAAYQALELNNDCATAYVLLAE--EEATTIVDAERLFKQALKAGETLVYIKRRLAMCARKLGRIREAVKIMRDLMKEFPTMLNIHENLLESLLELQAYPDVQAVLAKYDDISLPKSAAIYTAALLKTRTVSEKFSPETASRRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLHILKRGDSEAIAYAFFHLQHWKRIEGALNLLQCTWEGTFHHV........................ 470
62 -17.800[R] COG4783 Putative Zn-dependent protease, contains TPR repeats  ali follow..  36......................................................................................................................TSAGATLSIDQEMAMGDFYVRQMRASAPL---------DPLLTQYINTLGNRLVANANSVRT-----HFYLVNNDQINAFA--GNVVLHSALFRYTDNESELASVLAHEISHVTQRHLARAMEEQQRLAPLTWVGVLGSILLTMASPQAGMAGLSG------------TLAGAQQGIISFTQGNEQEADRIGIQVLQRSGFDPQAMPNFLQKLADQSRYVSKPPEM---LLTHPLPDSRLSDARNRANQMKPHPTASSQDYLFAKMRILGMYGADENSLTPELLDKLSKGTVREQAKYGQAVQLYQAKKYDEARNLLQPLLAQQPGNIWFLDLMTDIDLGQNKSAAAIARLQNAMVKQNDEPVLQLNLANAYVQGRQPAAAIKLLHRYTFAYPNDPNGWDLLAQATATQGLRQELAARAESLALSGKLTQAIGLLSDASARVKLGSLEQARYDARIDQLRRLNERFRKYQKS................................................. 486
63 -17.600[A] KOG1914 mRNA cleavage and polyadenylation factor I complex, subunit RNA14  ali follow..  3...............................................................................................................................................GLSMRNPERRIETNPFDVDAWNLL-LREHQSRPIDQERDFYESLVKQFPNSGRYWKAYIEHELRSKNFENVEKLFSRCLVSVLNIDLWKCYIHYVFETKGQRDQYREEMAKAYDFALEKVGMDVQATEYIAFLKKVPAVGQYAENQRITAVRKIYQKALATPMHNLELIWTLAEKLIAERGKEYQNARRVEKDLQQMTRGLNRQAVSV----KGTATEFKQVELWKNLIAWEKTNPLQTE-----EYGQHARRVVYTYEQSLLCLGYYPDIWYEAAMFLQEASHTLDEKGDVKMAQVLKLETISLYERAADFQEEHKQFEAVKNIYDRLLGIHINPTLTYVQLMRFIRRSEGPNNARLVFKRAREDKRTGYQVFVAAALLEYNC---------------MKDKEVAIRVFKLGLKKYENEPEFGLAYADFLSNLNEDNNTRVVFERILTSSKLPADKSIRIWDRFL-DFESCVGDLASILKVEKRRKTAYEE.... 502
64 -16.700[R] COG0790 FOG: TPR repeat, SEL1 subfamily  ali follow..  5...............................................................................................................FLSLCILAGVLFVSQVNASANNGK---DVKYAALTQKDLDALPV--EKRASVLDELGFIHEYPMNRERALQYYKQACELG--GNYGCYNVKYAYQY-KDSAQANKYAKKMNLD----------------------------------------NLLIEQEYIDKFSQEIYMAKALADTDKSQRAAFISILIHALNNRPESDALFFSRIGFNQEKTFRLATLWSQD------GDPQMDYQMGRLTLNYQARPASLKWFRAAAE-KGVVEAQSLLGGIYSGKPDIQEAQKWYGQAAK--QGDSDAQIALGKIYYS-TDYAKALALFTQVEN-DGTNSRSTMPLSWMYYNAPDCDKAWSYYKKASRKNNADALPKVTLKKERIFTAKPKECALIFQIGT--DKIRNMANLHITLELKNADGMATEETLMIPPFGLNTLPYDLPLYTQDF--CHGIGDIHFTLKSATATINGKNDSVRFLDK.................................................. 502
65 -16.500[B] KOG2084 Predicted histone tail methylase containing SET domain  ali follow..  10  5.........................................ATYHEICSAQTVQSERRGFFNEFCVDVRDACGDKWLRNYFGKLKSNAARVLSIFSDR----EVCDPVLGVLEHVQPVFKQKDALFSAQRRAQADKLYSRELLQQALMAANLAVMRAPDRALAYRSRASILIRLGEGEAALNDLKLAINFGELSVDYYLKMAKAYAVMGEPARAEISLKIAEKMPGCDATHIAL-CRKELSSVKPKPKEATSEQVPQLAHGESAELVGASKVVRLVETKDKGRFVVANEGLRTGDVLLFEAACLEPSYFGTHAFCSAQCMGEACSSYHRFECEYMDLMIGSGMSILCFIALRIFTQAPSLEQGLATANLLFEHLCSHEEDRQPDDYLRRALMSVATALLGLLQVLQYNAQIYQTQVTEEHRFDGSKTVYLAAGLYGTGSYFNPSTACHFVGKKLVLTATRPHELVAVNYGPIFIKNNLKERQRSLRGRYSFS--SCMACQENWPLLQKLDKPRCRKNISLKESVAKMIKIEELYREAARAMEAQKTVEAIELFKESLDMHKDTIVAQQSLHKCLSDTGTTFKKEG...................................................... 662
66 -15.900[T] KOG1309 Suppressor of G2 allele of skp1  ali follow..  15  2............................................................................................................................PVEKDLKTAYKALYDEKEPLKALHLYDEILKGSPTNLTALIFKAACLEKLATMENAKELLDKALMTRSKIGLVNFRYFVHFFNIKDYELAQSYFKKAK................................................................................................................................................................................................................................................................................................................................................................................................................................. 115
67 -15.900[R] COG5091 Suppressor of G2 allele of skp1 and related proteins  ali follow..  15  2............................................................................................................................PVEKDLKTAYKALYDEKEPLKALHLYDEILKGSPTNLTALIFKAACLEKLATMENAKELLDKALMTRSKIGLVNFRYFVHFFNIKDYELAQSYFKKAK................................................................................................................................................................................................................................................................................................................................................................................................................................. 115
68 -15.300[TDBLU] COG5032 Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family  ali follow..  1329....KIVDYLNKWLRMRKKRNWDRRSAIARKENRYMSVEDATSRESSISKVESFLSRFPSKTLGIVSL-NCGFHARALFYWEQHIRNATAPYAALESD---YRVLQEIYAGIDDPDEIEAVSLNFHDYSFDQQLLLHENSGTWDSALSCYEIIIQKDPENKKAKIGLLNSMLQSGHYESLVLSLDSFIINDNHEYSKMLNLGEASWRSLSIDS-LKKCLSKSNLESFEAKLGSIFYQYLRKDSFAELTERLQPLYVDAATAI--ANTGAHSAYDCYDILSKLHAIND-------FSRIAETDGIVSDNLDIVLRRRLSQVAPYGKFKHQILSTHLVGYEKTKKTAEIYLEIARISRKNGQFQRAFNAILKAMDLDKP-LATIEHAQWWWHQGQHRKAISELNFSLNKNRKETLGNPLKGKVFLKLTKWKDLETYYHKAVEIYSECENTHYYLGHHRVLM---------YEEEQKLPVNEQSERFLSGELVT------RIINEFGRSLYYGPKLLTLWLDFGAEELRLSKDDGEFREHIISSRKKSLELMNSNVCRLSMKIPQYFVALSQMSRVCHPNNKVYKILEHIIANVVASYPGETLWQLMATIKSTSQKRSLHSRKLSMSSKVDIKALSQSAILI 1982
69 -15.300[S] COG1729 Uncharacterized protein conserved in bacteria  ali follow..  16  245........................................................................................................................................................................................................................................................................................................................................................................................DPEELYRNSYQFILSGDYGTAEQGFRDHISRFPRDADAHYWLGESLLGQQKYRDAAEVFLAASKDYPKAPDMLLKLGVSLVGLKQHDVACATFSEVGKRYPDISSA............................................................................................................................................................. 356
70 -14.700[R] KOG4197 FOG: PPR repeat  ali follow..  10  83..............................................................................................................HVSYAYKLFVKIPEPDVVVWNNMIKGWSKVDCDGEGVRLYLNMLKVTPDSHTFPFLLNGLYSLCGLMDMARGVFD---RRCKEDVFSWNLMISGYNRMKEYEESIELLVEMERNLVSPTSVTLLLVLSACSK----------VKDKDLCKRVHEYVSECKTEPSLRLENALVNAYAACGEMDIAVRIFRSMKARD--------VISWTSIVKGYVERGNLKLARTYFDQMPVRDRISWTIMIDGYLRAGCFNESLEIFREMQSMIPDEFTMVSV-DMYFKCGCSEKAQKVFHD---MDQRDKFTWTAMVVGLANNGQGQEAIKVFFQMQDIQPDDI-TYLGVLSACNHSGMVDQARKFFAKMRSDHEPSLVHYGCMVDMLGRAGLVKEAYEILRK-MPMNPNSIV-----GALLGASRL-------------HNDEPMAELAAKKILELEPDNGAVYALLCNIYAGCKRWKDLREV-DVAIKKTPGFSLIEVNGFAHEFVAGDKSHLQSEEIYMKLEELAQESTFAAYL 650
71 -14.500[S] COG4259 Uncharacterized protein conserved in bacteria  ali follow..  49............................................................................................................................................TSLGKQTEKMEKYFV-MNAAPGAHAHLGLLLSRSGDKEGAFRQFEEEKRLFPESGVFMDFLMKTGKGGKR............................................................................................................................................................................................................................................................................................................................................................................................................................................. 123
72 -13.300[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali follow..  10  14..........................................................................................................................................GMEDLDEEIQKIKQKMIDDSQSVVLANQLLILLRKNGDFDELDIKRRQFVEWAPLNPLNWKNWIEDFQNRKPFEKALFDENDVTIWVER--MYAYKVANDKNKKEDFKFCRDVCSKALENLGTRYDSGGHIWLIFLEYEMSYLKNAPDYQRLADQVFALFERALHCPTDQLEDVY--------VLAEQFCTEFKQHHKLEELKKTYNSTM-----------RQKEQLSKFEELIQQEEKKQGLKQFFDHEKKSGIPSRIKMAHERLVSELDDDEEAWIAYGAWADIELKLQVAVKVYSRALRHCPYSFVLHQQALLAFERDRRNEEIDALWERARSNVINSAE-LLRRRIHLTGSSDYSPMAEVFDEGAALLREWFSMAWDTTADYRQMQAYFYA-------SLMKNMDKCRNIWNDILA-FGRFAGKWIEAVRLERQFGDKENARKYLNKALNSVSDNINEI...................................... 476
73 -13.000[S] KOG4459 Membrane-associated proteoglycan Leprecan  ali follow..  25..............................................................................................................................................................................................................................................................................................................................................ESEAGWGMVTPDLLFAEGTAAYARGDWPGVVLSMERALR----FGGLLRRAACLRRCLG-PPAAHSLSEEMELEFRKRSPYNYLQVAYFKINKLEKAVAAAHTFFVGNPEHMEMQQNLDYYQTMSGVKEADFKDLETQ--------MQEFRLGVRLYSEEQPQEAVPHLEAALQ---AYEECRALCEGPYDYDGYNYLEYNADLFQAITDHYIQVLNCKQNCVTFEDFLPSHYNYLQFAYYNIGNYTQAVECAKTYLLFFPNDEVMNQNLAY-----YAAMLGEEHTRSIGPRESAKEYRQRSLL 371
74 -12.900[S] COG3014 Uncharacterized protein conserved in bacteria  ali follow..  21........................................................................................................................................................................................................................................................................................................................................................................................GYRMDLEHFNTLYYEESPKKAYEYSKQFTKKKKNALLWDLQNGLSALYARDYKTSLGVLDQAEQRFDKTQSAFTRGAGYVGATMINDNVRNIYEGVL--------INYYKAIDYMLLNDSAKARVQFNRANERQRRAKEFY-------------------------YEEVQKAIKEIDSSKKHNINNPAVSYLSGLFYALNGDKNKGLGYLNEAYGISQS........................................... 240
75 -12.700[S] KOG3783 Uncharacterized conserved protein  ali follow..  10  8.....................................................................................................FGSKGNQSSGEEQSTKTKQVLKQANDFEIALKAMDFVLDDRTDEGLNLLKKAEMETGSDQTILT-QATLSFETEEMKRAAITLGKAEQMSWKYTESCLLHALLMLFSESMMEAAKALKLRRAYTMLQDIMVTVKKAERSKNSSSPSPSEKSQESCGSFVSAETTFISVDIPYKLSSEDKSNPLLLEFAEKIYTMRMGRLSGAHIGNTPSFHRLRDDLGLQTTPSQASDRHSVSDDFDLEQATIDEFIHSYGILQVVKGSREEGLRLVWKATKERNVHGCIGLLGLMFYLLHPGKILEDALLKARALFPNSALWLLNEAKMLAGKGRLRDSLALMDSIDVNSIRKSLMVFERAILLVNLHEYNRAADDLISLLDISDWSHALYTYFGCCYLENWR-GKEQFYKERAREL--FDAPSLLGKKTFKSKNLPLDRFMLRKVQQFNNMQKKLNLQEPLDSIATSPVHELAYF-LSLTLRRLGDAERGLALLDDIVLPKIFYIQALYERALFCWKLGGESLNECREWLLRAQNYAADYELSTRI 715

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.