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Query: [S] KOG0858 Predicted membrane protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDAGVWYRSLPRFTRYWLTATVVLSMLCRFDVIPLHWLHLDRSAVFSKLQLWRCMTSLFVFPISSNTAFHFLINCFFIVQYSSKLEKDQYSRSPADYLYLLIVSAVLANIGGMIFNVYFLMDTLVLAITYIWCQLNKDVTVSFWFGTRFKAMYLPWVLAAFEFIFHFSLASLVGIFVGHVYYFFKFQYSQDLGGTPLLETPQFLKRLVPDVSGGFGGFGLPPESRAPPRQATESPWGRGMTLGRNLast
1 -115.000[S] KOG0858 Predicted membrane protein  ali  100  1MDAGVWYRSLPRFTRYWLTATVVLSMLCRFDVIPLHWLHLDRSAVFSKLQLWRCMTSLFVFPISSNTAFHFLINCFFIVQYSSKLEKDQYSRSPADYLYLLIVSAVLANIGGMIFNVYFLMDTLVLAITYIWCQLNKDVTVSFWFGTRFKAMYLPWVLAAFEFIFHFSLASLVGIFVGHVYYFFKFQYSQDLGGTPLLETPQFLKRLVPDVSGGFGGFGLPPESRAPPRQATESPWGRGMTLGRN 245
2 -82.300[S] COG5291 Predicted membrane protein  ali follow..  22  11.FLLGQMLRVPPITRYMTLLISAVALLVYVDAVSPYSLYYSPL-FLKRLEIWRVFTSFLYFGKPT---LDMFMHVVFLYRYSRMLEEGCV--NTSEYFWLILVISSVLFAISNIYGISALGTSFSATITYIWTKRNPRAIVQIFGFISFPAFYLPFILPGFMLLSRRSIDDVLGIVVGHLFHYFKDVYPR--WGRDILSTPCWVKKLFNEHPSSCCKARKGIERHERNMGYSNASTTSGDSMASL 254
3 -30.100[S] KOG4463 Uncharacterized conserved protein  ali follow..  12  1MSSANIVPSNMGITKFLLLTISTSSVVAGVFALKPFFHINFGLHLLSHYQYWRILLWQFIYWNSTEVFQALFIIYQA-----RDVERLLGSHRFASFCVYMFILGMFVTPIFSFLYSLLFKTFLIFAILYQYYYIVPSTVFVRLFNIKFTDKFQMVIPMIGLAFSHFPINAFLGWTMGMFYHL----------PGTSWRLPIRFVKPALSPTHVFIRPPYSDMQNASTFNPE............. 232
4 -24.900[S] KOG2632 Rhomboid family proteins  ali follow..  16  13TRVGQWWNAIPFLTSSVVVVCGVIYLICLLGYDTFYEVCFLPSAIISRFQVYRFYTAIIFHGSLLHVLFNMMALVPMGSELERIMGSVRLL-----TVLLATTNAVLHLLIASLAGYNPFFSGILFSMIVIETSLSGVTSRSVFGLFNVPAKLYPWILLIVFQLLMTNVSHLCGILSGFSYSYGPSSLCVLAGILPAIFPLILHKTQHPGNAWRSLSSWLPQREASNQSSEDSRFPGRGRTLSTA 311
5 -23.200[S] KOG2890 Predicted membrane protein  ali follow..  15  16.RHSDVLRNNALPFRFLVVLRIIGYIISYLHFARLL-LWLHPYQIA-SIELWRIATSTFCGHNV----LDVLWTVWCLHFGTNLVRLNNTNESLLKLYAITQGVTTFVIVVFAYLTYILFMTPICASVMVLMKQFLPDTIVLATPLGRIKYAHLPFLAIFVSFILASFLQITIGVQVSWTY................................................................ 210
6 -13.300[R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)  ali follow..  18  92........RAGPVTWIVMLACVLVYIAMSLGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSL----MHILFNLLWWWYLGGAVEKRLGSGK---LIVITVISALLSGYVQQKFSGPWLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAGWFDWFGMSMAHIAGLIVGLAMAFV............................................................. 267
7 -12.500[T] KOG2980 Integral membrane protease of the rhomboid family involved in different forms of regulated intramembrane proteolysis  ali follow..  10  143..........KNLVYALLGINVAVFGLWQLPKCWRFLQKYMLLQKDYVTSKISIIGSAFSHQEFWHLGMNMLALWSFGTSLATMLGASNFF---SLYMNSAIAGSLFSLWYPKLARLAIVGPSLLFGVLGCFSYLFPHAKILLFVFVPGGAWVAFLASVAWNAAG-DYAAHLGGSMMGVLYGWYISKAVEKQRQRRLQAAGRWF......................................... 346
8 -8.480[T] KOG2290 Rhomboid family proteins  ali follow..  11  603......TKGRCEITSREYCDFMRGYFHEEATLCSQVH-LLPFLNPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIA-----IIYLLSGVTGNLASAIFLPYRAEVGPALFVELFQSWQILARPFKLLAVVLFLFTFGLLPWI---------DNFAHISGFISGLFLSFA............................................................. 785
9 -7.350[T] KOG2289 Rhomboid family proteins  ali follow..  12  104............................................VVHEHQGWRLLSCMWLHAGIIHLLTNMLSLIFIGIRLEQQFGFIRVG-----LIYLISGLGGSILSSLFLQESISVGASMLSELLTNWTIYANKITLLFIIAINLALGMLPRV---------DNFAHIGGFLTGFCLGFV............................................................. 242
10 -7.240[S] KOG4790 Uncharacterized conserved protein  ali follow..  12  14..LETFLESAPQLVLQLYIMLTLPCVSSVTSLMSLAWVLASYHKLLRDSRFWRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFC--WFNVKEGRTRYRMFAYYTIVLTENAALTFLWYFYRDPETTDSYAVPALCCVFIS---FVAGIAMMLLYYGV............................................................. 218
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;