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Query: [A] KOG1295 Nonsense-mediated decay protein Upf3, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSSKDIGEVVQFRDRFDGYVFVDHKGVEYMAIVEYAPFQCFLKNKARNDDSKVNTIESEPHYQEFIKRLAQEREEASRMGDVKIDFNFERRTEEKVKSTPLLQYLANKKEKRREEARRRNEEKRKQREEQKLLRLAAQSDASKLKEAEGGGGGGDTKKPAKKDVKDPQSSGSQANDAKASRSKRRTERDQRRREEHEQRKLVKRDKKKDDGQGKQDKQDKQDKGKPSSGKQNKNSKSMDIVILKKANKPESNESLDVPSTSNAAEASKEKPATENTETPEAAVKVFTPAARGGRKEKRTGADKQPAGSAHETAEEAIKAAQFRASEERRIRNKVGLTYYPPRHFTNPLDVYRIDHRLPFTSPKPEFVHQMSCPKVQAAKMARMERLPWWRRRLRRGTNAPIGATNPNRRRLast
1 -75.000[A] KOG1295 Nonsense-mediated decay protein Upf3  ali  100  1MSSKDIGEVVQFRDRFDGYVFVDHKGVEYMAIVEYAPFQCFLKNKARNDDSKVNTIESEPHYQEFIKRLAQEREEASRMGDVKIDFNFERRTEEKVKSTPLLQYLANKKEKRREEARRRNEEKRKQREEQKLLRLAAQSDASKLKEAEGGGGGGDTKKPAKKDVKDPQSSGSQANDAKASRSKRRTERDQRRREEHEQRKLVKRDKKKDDGQGKQDKQDKQDKGKPSSGKQNKNSKSMDIVILKKANKPESNESLDVPSTSNAAEASKEKPATENTETPEAAVKVFTPAARGGRKEKRTGADKQPAGSAHETAEEAIKAAQFRASEERRIRNKVGLTYYPPRHFTNPLDVYRIDHRLPFTSPKPEFVHQMSCPKVQAAKMARMERLPWWRRRLRRGTNAPIGATNPNRRR 410
2 -13.000[S] KOG4610 Uncharacterized conserved protein  ali follow..  7  299..............................................................................................................KNSLVIILQLYRLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS........................................................................... 523
3 -11.500[R] KOG2295 C2H2 Zn-finger protein  ali follow..  8  173..........EVMRKYTEY-FVAHKDEEW----KYHP-EDSVKRSEEQRGFLQRRTD------VFMELLENQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRA............................................................................ 510
4 -11.200[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  10  566.EFSDVNE--ELMKLWNLHVFLDAKGTEIVR--NFILH-------------DYGLIAAE-TVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAPHRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHRPPPPPPPQ............................... 955
5 -9.370[P] KOG4505 Na+/H+ antiporter  ali follow..  7  362...................LFAGHFGPIGVGALYTCLVAELEVHSTVPEPNDAIENPEIPNWYCIVHGSSIAFFMLGKRINTLALSFTRTRDSHFAFNLPRVRQGQSLPIKRVDALRSSANSIASSIRRRHPVNIQEDEDADISTVSLPEAAHLREERAESPRGGHYDAEEFPSEDYESRQPRRSNEEDREEEMNPGDETYLIGEDLVVEDSQGNIISHTSSRDANGPSIDEKLAQGDPKAKSFGRKFRSFLRRSYDTFQRNLHEPDDERQREPTLGHIESSIENHRPRYSRQNSESHLRENSVERRRREQVLTNIGDSESEDDNIPRPGIVPFYNENNESSSDTRNGLLSDNVSESRSRRPSRAPSAAVSSEGSPVEEDNEAQHRPNIRFLELTRAWE........... 759
6 -8.910[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  9  255.........................................................................................................SRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMSD........................................................................... 484
7 -8.870[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  10  469......................DAAAGEYSSAIE-----------------KQSKVAHDERCKILISSLQDT-----------------------------LHGIEAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDTDAHWIIKQQTTSIPAPPSSQQN........................................................................................................................... 696
8 -8.520[U] KOG0946 ER-Golgi vesicle-tethering protein p115  ali follow..  6  610..........................................................DHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRLREEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQKILSLKNKLKDLGHPVEEEDELESGDQEDEDDESEDPGKDLDH 961
9 -7.610[S] COG5291 Predicted membrane protein  ali follow..  8  202.................................................................................................STPVKKLFNEHPSSCCKARKGITIREGRERHERNMGYSNASTTSGDSMASLTDMADTKSSTENSAVTEESQCCAESFKDSSVVSSQKSMAVSTVVGSSTEAKNNYLDFTEALCDKEVVAEQNPESQSNEEWDEKWGDSDNESECS........................................................................................................................................................................ 348
10 -7.090[A] KOG2242 Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain  ali follow..  8  2..........................................................DVRRLKVNE---------------LREELQRRGLDTRGLKTELAERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDT................................................................................................................................. 209
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 2 6 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.