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Query: [R] KOG1491 Predicted GTP-binding protein (ODN superfamily), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPPKKQVEEKKVLLGRPGNNLKAGIVGLANVGKSTFFQAITRCPLGNPANYPFATIDPEEARVIVPSPRFDKLCEIYKKTASEVPAHLTVYDIAGLTKGASAGEGLGNAFLSHIRSVDSIYQVVRCFDDAEIIHVEGDVDPVRDLEIINQELRLKDIEFAQKALEGAEKIAKRGGQSLEVKQKKEEMDLITKIIKLLESGQRVANHSWTSKEVEIINSMFLLTAKPCIYLINLSERDYIRKKNKHLLRIKEWVDKYSPGDLIIPFSVSLEERLSHMSPEDAEEELKKLQTISALPKIITTMRQKLDLISFFTCGPDEVREWTIRRGTKAPQAAGVIHNDLMNTFILAQVMKCEDVFEYKDDSAIKAAGKLMQKGKDYVVEDGDIIYFRAGAGKNLast
1 -137.000[R] KOG1491 Predicted GTP-binding protein (ODN superfamily)  ali  100  1MPPKKQVEEKKVLLGRPGNNLKAGIVGLANVGKSTFFQAITRCPLGNPANYPFATIDPEEARVIVPSPRFDKLCEIYKKTASEVPAHLTVYDIAGLTKGASAGEGLGNAFLSHIRSVDSIYQVVRCFDDAEIIHVEGDVDPVRDLEIINQELRLKDIEFAQKALEGAEKIAKRGGQSLEVKQKKEEMDLITKIIKLLESGQRVANHSWTSKEVEIINSMFLLTAKPCIYLINLSERDYIRKKNKHLLRIKEWVDKYSPGDLIIPFSVSLEERLSHMSPEDAEEELKKLQTISALPKIITTMRQKLDLISFFTCGPDEVREWTIRRGTKAPQAAGVIHNDLMNTFILAQVMKCEDVFEYKDDSAIKAAGKLMQKGKDYVVEDGDIIYFRAGAGKN 394
2 -95.300[J] COG0012 Predicted GTPase, probable translation factor  ali follow..  22  1....................MEIGVVGKPNVGKSTFFSAATLVD-VEIANYPFTTIDANVGVTYAAEHPCKELGCKPNPQNGLALIPVKMIDVAGLVPGAHEGRGLGNKFLDDLRMASALIHVVDVTGKTDEGQPTENHDPIEDIEFLEREIDYWIYGILSKGWDKFAKRIKLQRIKLESAIAEHGVTENDVWEAMHRLGLPSDPTLWSQEDLLAFASEIRRINKPMIIAANKADAASEEQELTLRKAAKAGFIDYIPGSSEFKILKDMNERQKKALLMIKEKVLDRFGSTGVQEVINKAVFELLNLIPVYPVGNVLPHVFLMKKGSNPRDLAFKVHTDLGRGFLYAI-----------------NAKTKRRIGEDYELQFNDIIKIVAVTK.. 397
3 -38.700[R] COG1163 Predicted GTPase  ali follow..  17  49...GSGGGAGIGFDVARTGVASVGFVGFPSVGKSTLLSKLTGTE-SEAAEYEFTTLVTVPGVIRYKG------------------AKIQMLDLPGIIDGAKDGRGRGKQVIAVARTCNLLFIILDV-------------KPLHHKQIIEKELEGVGIRLNKTPPDILIKKKEKGGISITNTVPLTHL---------------------GNDEIRAVMSEYRINSAEIAFRCDATVDDLIDVLEASSRRYMPAIYVLNKID-------SLSIEELELLYRIPNAVPISSGQDWNLDELLQVMWDRLNLVRIYTKPKGQIPDFLRSDRCSVKDFCNQIHKSLVDDFRNALVYG----------SSVKHQP--QYVGLSHILEDEDVVTI....... 366
4 -38.200[T] KOG1487 GTP-binding protein DRG1 (ODN superfamily)  ali follow..  18  48...GGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVY-SEVAAYEFTTLTTVPGVIRYKG------------------AKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDV-------------KPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELD---------------------AETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKID--------QISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTQLPDYTSPVVLPYSRTVEDFCMKIHKNLIKEFKYALVWG----------LSVKHNP--QKVGKDHTLEDEDVIQI....... 364
5 -38.000[T] KOG1486 GTP-binding protein DRG2 (ODN superfamily)  ali follow..  14  44.PPKGASGGGEGFEVTKYGHGRVALIGFPSVGKSTLLTMLTGTH-SEAASYEFTTLTCIPGVIHYND------------------TKIQLLDLPGIIEGASEGKGRGRQVIAVAKSSDLVLMVLDA------------SKSEGHRQILTKELEAVGLRLNKTPPQIYFKKKKTGGISFNTTAPLTHIDE---------------------------------LCYQILHEYKIHNAEVLFRENATVDDFIDVIEGNRKYIKCVYVYNKIDIDDVDRLSRQPNSIVISCNLKLNLDRLLARMWDEMGLVRVYS--DEPFVLSSDRGGCTVEDFCNHVHRTLVKDMKYALVWG----------TSTRHNP--QNCGLSQHLEDEDVVQIVKKKER. 370
6 -24.100[R] COG0536 Predicted GTPase  ali follow..  18  143...IGEPGEAHDLILELKSMADVGLVGFPSAGKSSLISVMSAAK-PKIGDYPFTTLQPNLGVVNVGHETF------------------TMADVPGLIPGASEGKGLGLDFLRHIERTSVLVHVV------DTATMDPGRDPISDIEALEAELAAYQSALDED------------------------------------------------------TGLGDLSQRPRLVVLNKADVPEAEELAEFLKED----IEKQFGWPVFIISAVARKGLDPLKYKQDARKKRPKEKAESVIIKPKAVDHRTKGQFQIKPDPEVQGGFII-TGEKPERWILQTDFENDEAVGYLA----DRLAKLGIEDGLRKAG----------AHVGANVTI....... 433
7 -23.100[R] KOG1489 Predicted GTP-binding protein (ODN superfamily)  ali follow..  22  320FSKPGRNGLEQHFLFELKSIADLGLIGLPNAGKSTILNKISNAK-PKIGHWQFTTLSPTIGTVSLGFGQ----------------DVFTVADIPGIIQGASLDKGMGLEFLRHIERSNGWVFVLDL----------SNKNPLNDLQLLIEEV----------------------------------------------------------------GTLEKVKTKNILIVCNKVDIDAEKSESFAKYLQVEKF-SKSQEWDCVPISALREKT.......................................................................................................................... 499
8 -17.900[R] KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily)  ali follow..  17  170.....................TVLICGYPNVGKSSFMNKVTRAD-VDVQPYAFTTKSLFVGHTDYKYLR------------------YQVIDTPGILDRPFEDRNCSITALAHLRAAVLFFLDISGSCGYTIA------QQAALFHSIKSLFMNKPLVIVCNKTDLMPMENISEEDRKLIEEMKSE................................................................................................................................................................................................................ 313
9 -17.100[R] COG1084 Predicted GTPase  ali follow..  18  164.....................TVVIAGFPNVGKSTLLRTLTGAE-PEVADYPFTTKGIQIGHLERKWKR------------------IQVIDTPGLLDRPEDMNNIELQAMVALNIADVIMFIFDASETCGYTLESQYSLYLGIRSVFDIPVVTMDLAENVKYLEEYIN................................................................................................................................................................................................................................. 298
10 -15.200[R] COG3596 Predicted GTPase  ali follow..  17  19LPLWVSERILQQINQLTHYEPVIGIMGKTGAGKSSLCNALFAGEVSPVSDVAACTRDPLRFRLQIGE------------------HFMTIVDLPGVGESGVRDTEYAALYREQLPRLDLILWLIKADDRALATDEH--------YRQVIGEAYRHKMLFVISQSDKAEPTSGGNILSTEQKQ.................................................................................................................................................................................................................... 175
11 -13.400[P] COG0370 Fe2+ transport system protein B  ali follow..  13  2..................SQNTYCILGNPNTGKTSLFNALTGSY-EYVGNWSGVTVEKKVGTLR---------------------KTGKLIDLPGILNPISRDETVVTRFLLE-EKFDCMLNIVDSSQGAPVVMGLNMIDVAANIQNLAKKLRIPILPVVARSGKGTEDILSTLSEKHVAPAIPLVLQYGEPAEKAIKEIQALTKELIPAKQSRWLAIQFLSKNEVTEFLTSNSAFEQLQQIRAELESELNGKLENHFHQVRASYIHDICLTSVEYTRNSDIPLSDKLDKIFTHKLLGIPIFLGIMWLIFFTWVGAPLSDMLVTSFLTTIGASGFIIDLVADGFFFISVLEDSGYMARIAVVMDRVMEIFGLNGKAFI-----IIGFGCNVPG. 406
12 -12.600[R] COG1159 GTPase  ali follow..  13  11......................IAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGP------------------YQAIYVDTPGLHMEEKRNRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDGKAPVI---LAVNKVDNVQEKLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHLPEAIHHFPEDYIEIIREKLMRFLGAELPYSVTVEIERFVTNERGGYDINGLILVEREGQKKMVI-GNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKV.............................................................................................. 281
13 -11.600[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  12  51...............RRTKSNTVLLSGLSGSGKTVLFYQLRDGSSHQGA---VTSMEPNEGTFVLHNE---------NNTKKGKVKPVHLIDVPG--------SRLISKLEEYLPRAAAVVFVVDALEFLPNIRAASEYDILTNASVIKNKTPVTDKKQMEKEIDKLRVSRSAISTADIANDFTLGIEGEVFSFSHCHNKVTVAEASGLTGETDQVQEFIREHVKP........................................................................................................................................................................ 260
14 -11.100[R] KOG2486 Predicted GTPase  ali follow..  13  137.....................EFALVGRSNVGKSSLLNSLVRRKLALTSKKPGKTQCINH----------------------RINDKWYLVDLPGY-ELKQDWNKFTKDYFLNRSTLVSVFLLV---------------DASIPVKPIDLEYA-VPMTLIFTKCDKRKKKKNGGKKPEANIKEFQDL............................................................................................................................................................................................................... 279
15 -10.400[E] COG4917 Ethanolamine utilization protein  ali follow..  20  3.....................RIAFVGSVGAGKTTLFNALQGNYTL------------------------------ARKTQAVEFNDKGDIDTPGEY---FNHPRWYHALITTLQDVDMLIYVHGANDPESR...................................................................................................................................................................................................................................................................... 80
16 -10.000[R] COG1160 Predicted GTPases  ali follow..  14  5.....................VVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHIAGYDF------------------IVIDTGGIDGTEEGEEKMAEQSLLAIDEADIVLFLVDA----------------------RAGLTAADIGIANYLRQRQNKITVVVANKTD-----------------------------GIDADSHCAEFYQLGLGEIEQIAASQGRGVTQLMEQVLAPFAEKMENADENDRTSEEEQDEWEQEFDFDSEEDTALIDDALDEELEEEQDKNI--KIAIVGRPNVGKSTLTNRILGEDRVVVFDMPGTTRDSIYIPMERDGQQYTLIDTAGVRKRGKVHLAVEVIKTLQAIQDANVVLLTIDAREN 310
17 -9.360[R] COG2262 GTPases  ali follow..  23  199.....................TVSLVGYTNAGKSTLFNRITEARV--AADQLFATLDPTLRRIDVADVG-----------------ETVLADTVGFIRHLPHD----KATLQETRQATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLL................................................................................................................................................................................................................................................ 314
18 -9.120[T] KOG3886 GTP-binding protein  ali follow..  22.PLGEPEGSLGWVLPNTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATILDRIHSLQINSSLSTYSLVDSVGNTKTF-LVLNLWDCGG--QDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIF---CLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVISHYQCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVVSDPSIPSAA.......................................................................... 346

FFAS is supported by the NIH grant R01-GM087218-01
1 3 6 3 0 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Veeramalai M, Ye Y, Godzik A. TOPS++FATCAT: fast flexible structural alignment using constraints derived from TOPS+ Strings Model. BMC Bioinformatics. 2008 Aug 31;9(1):35