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Query: [F] KOG1567 Ribonucleotide reductase, beta subunit, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADFLast
1 -112.000[F] KOG1567 Ribonucleotide reductase, beta subunit  ali  100  1MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF 351
2 -79.900[F] COG0208 Ribonucleotide reductase, beta subunit  ali follow..  22  3.....RQEAKRMKATMAYSTFTQKKNDQLKEPMFLGQPVNVARYDQQKYEIFEKLIEKQLSFFWRPEEVDVSSDRIDYGKLPDHEKHIFISNLKYQTLLDSIQGRSPNVALLPLVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPAVVFDDIVENEHIIKRAKNGETITVSLKELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIKLIARDEALHLTGTQHMLNLLRNGMDDQESFDLFKEAAEQEKEWAEYLFKDGMIGLNKDILCQYVEYITNIRMQAVGLEPAYPANNPIPWINAWSDNVQVAPQEAEISSYLVGQIDNEVSADDFE-GFEL 389
3 -23.100[S] COG3396 Uncharacterized conserved protein  ali follow..  7  9..................................................................QRIAQETAIEPQDWMPDAYRKTLIRQIGQHAHSEIVGMLPEGNWITR-APTLRRKAILLAKVQDEAGHGLYLYSAAETLGCAREDIYQ---------KMLDGRMKYSSIFNYPTLSWADIGVIGWLVDGAA-----IVNQVALCRTSYGPYARAMVKICKEESFHQRQGFEACMALAQGSEAQMLQDAINRFWDDNSPNSARSLTWKIKRFTNDELRQRFVDNTVPQVEMLGMT................................................... 239
4 -18.700[S] COG2833 Uncharacterized protein conserved in bacteria  ali follow..  9  32.........................................................RETASRWFARALSVRSPLRMLKKRSLNTEHGRIALMHALAHIELNAIDLALDIVARFAVKPSFFDGWMKVADDEARHFTLLRNRLKSLGAD-------------YGDMPAHDGLWQSAHQTRNDLEARLAVVPLILEARGLDVTPSLLEKMIETG--HETAAILNIIYNDEKTHVAVGAKWFRFFCARNRIDPAARFRELVRANFRGELKPPFNELAAGLTPSFYRSLSPVSI............................................................. 275
5 -12.100[S] COG1633 Uncharacterized conserved protein  ali follow..  13  13...................................................................................RNLKGIEEAIALAIDREK--AREFYLQQAGLMENPKFKELYEELAAEEMKHLGYLENYRDKKELPEISTEVPSGQSFSPEFDASRTKVGEITLGDAG-----ILLAAMRHE-----KSEDFYSEMAKRVEDETQKKFFEMLSRYERGHYEVIDSYLEYITQFR......................................................................................................... 165
6 -10.800[R] COG3687 Predicted metal-dependent hydrolase  ali follow..  14  73SGIYVNAVATFSEGAAMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDW------TNLPFHYVPNEPMATHVLNVLHMLLPAGEEFFVRVFK---------------KTLPLIKDDQLRLDVQGFIGQEAMHSQAHSGVVDHFDAQGVDVTAFTNQIRWLFEKLLGES-PRRSPRRQYSWLLEQVSFIAAIEHYTAVMGEWIL-QLDAVGADPVMLDMLRWHGAEEVEHKAVAFDTMKHL............................................................................................................. 294
7 -9.030[R] COG2406 Protein distantly related to bacterial ferritins  ali follow..  10  1......................................................................MARVAREMVEKAGVDVDKLLELLIKNAAAELTTYYYYTRANLIGLEGETIKEIAEVARIEDRNHFEALVPRIYELGGKLPDCMKEFHDLSACPPAR-----------PDKPTVQEILRVLVAAERCAVKGYTEICNMTAGKD--HRTYELSLAILNEEIEHESWFSEFLGE.............................................................................................................. 161
8 -8.830[S] COG4902 Uncharacterized protein conserved in archaea  ali follow..  8  44..............................................................................APLSDEEANSLLYMIE-----EEKLARDVYLKLYNETGLI----IFDRIAQSEQRHMDAVLMLIEKYNLTAPDTLNEIGVFENEELQNLYNELVEMGSQSVVDALKVGA-----IE-----IDIKDLEEWLSKVDNEDIKVVFENLMDGSKNHLRAFTKVLADNYGI.......................................................................................................... 193
9 -8.800[S] COG3685 Uncharacterized protein conserved in bacteria  ali follow..  11  2..................................................................................ATANEHLVAWLRDAHAMEEQAITMLTSQSSRLENYPELKTRIDRHLQETKDQAAMLERCLERLDGGTSSIKD--------ISGKIVAFGQGLSGLFVSDEVVKGTLASYTFEHMEI-ASYRILIAAAEQAGDQETKRVCESILQQEIAMAEWLAQNAGEITRK.......................................................................................................... 155
10 -7.860[P] COG3546 Mn-containing catalase  ali follow..  12  11...................................................................TVRVSEPNPGLANL-------LLEQFGGPQGELAAACRYFTQGLS--DDDAGRREMLMDIATEELSHLEIIGSLVGMLNKGAKGELAEGTENEAELYRSLTQNGNDSHITDTIGEVTADLRSNIAAE----ARAKIIYERLINLTDDPGVKDTLSFLMTREVAHQLSFEKALYSIRNNFPPGKLPP.................................................................................................. 206
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zmasek CM, Zhang Q, Ye Y, Godzik A. Surprising complexity of the ancestral apoptosis network. Genome Biol. 2007 Oct 24;8(10):R226 [Epub ahead of print]