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Query: [A] KOG1914 mRNA cleavage and polyadenylation factor I complex, subunit RNA14, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSGLSMRNPERRIETNPFDVDAWNLLLREHQSRPIDQERDFYESLVKQFPNSGRYWKAYIEHELRSKNFENVEKLFSRCLVSVLNIDLWKCYIHYVFETKGQRDQYREEMAKAYDFALEKVGMDVQAYSIFTEYIAFLKKVPAVGQYAENQRITAVRKIYQKALATPMHNLELIWNDYCTYEKAINITLAEKLIAERGKEYQNARRVEKDLQQMTRGLNRQAVSVPPKGTATEFKQVELWKNLIAWEKTNPLQTEEYGQHARRVVYTYEQSLLCLGYYPDIWYEAAMFLQEASHTLDEKGDVKMAQVLKLETISLYERAITGLMKESKLLYFAYADFQEEHKQFEAVKNIYDRLLGIEHINPTLTYVQLMRFIRRSEGPNNARLVFKRAREDKRTGYQVFVAAALLEYNCMKDKEVAIRVFKLGLKKYENEPEFGLAYADFLSNLNEDNNTRVVFERILTSSKLPADKSIRIWDRFLDFESCVGDLASILKVEKRRKTAYEEAQKDQTMNHSMLVIDRYKFMDLMPCSGEQLKLIGYNALKGTESIAGPSFVGSKNVPTHGPQAASAIMGGAGGHADVARYGFPRPDISQMIPFKPRVNCTASFHPVPGGVFPPPQSVAHLMSLLPPPTCFIGPFINVELLCNMINNMQLPNVSYPKSEDNMLGPMLEQDVKKDMYQLLATTSDPSAVVRSSALSDLKRKRGDSDDEEDYSHLGAVIGSLGSRDAYKRRMNKKNELast
1 -131.000[A] KOG1914 mRNA cleavage and polyadenylation factor I complex, subunit RNA14  ali  100  1MSGLSMRNPERRIETNPFDVDAWNLLLREHQSRPIDQERDFYESLVKQFPNSGRYWKAYIEHELRSKNFENVEKLFSRCLVSVLNIDLWKCYIHYVFETKGQRDQYREEMAKAYDFALEKVGMDVQAYSIFTEYIAFLKKVPAVGQYAENQRITAVRKIYQKALATPMHNLELIWNDYCTYEKAINITLAEKLIAERGKEYQNARRVEKDLQQMTRGLNRQAVSVPPKGTATEFKQVELWKNLIAWEKTNPLQTEEYGQHARRVVYTYEQSLLCLGYYPDIWYEAAMFLQEASHTLDEKGDVKMAQVLKLETISLYERAITGLMKESKLLYFAYADFQEEHKQFEAVKNIYDRLLGIEHINPTLTYVQLMRFIRRSEGPNNARLVFKRAREDKRTGYQVFVAAALLEYNCMKDKEVAIRVFKLGLKKYENEPEFGLAYADFLSNLNEDNNTRVVFERILTSSKLPADKSIRIWDRFLDFESCVGDLASILKVEKRRKTAYEEAQKDQTMNHSMLVIDRYKFMDLMPCSGEQLKLIGYNALKGTESIAGPSFVGSKNVPTHGPQAASAIMGGAGGHADVARYGFPRPDISQMIPFKPRVNCTASFHPVPGGVFPPPQSVAHLMSLLPPPTCFIGPFINVELLCNMINNMQLPNVSYPKSEDNMLGPMLEQDVKKDMYQLLATTSDPSAVVRSSALSDLKRKRGDSDDEEDYSHLGAVIGSLGSRDAYKRRMNKKNE 735
2 -90.300[A] COG5107 Pre-mRNA 3`-end processing (cleavage and polyadenylation) factor  ali follow..  22  24.IHGDELRLRERIKDNPTNILSYFQLIQYLETESYAKVREVYEQFHNTFPFYSPAWTLQLKGELARDEFETVEKILAQCLSGKLDLSLWSTYLDYIRRKNNLIQEARAVIVKAFQLVMQKCAIFPKSSSFWNEYLNFLEQWKPFNKWEEQQRIDMLREFYKKMLCVPFDNLEKMWNRYTQWEQEINSLTARKFIGELSAEYMKARSLYQEWLNVTNGLKRASPINLRGTSDSNIQQLQIWLNWIKWERENKLMLSE-DMLSQRISYVYKQGIQYMIFSAEMWYDYSMYISEN-----------------SDRQNILYTALLAN-PDSPSLTFKLSECYELDNDSESVSNCFDKCTQKQREKLTFVFCVYMNTMKRISGLSAARTVFGKCRKLKRLTHDVYVENAYLEFQNQNDYKTAFKVLELGLKYFQNDGVYINKYLDFLIFLNKDSQIKTLFETSVEKVQ-DLTQLKEIYKKMISYESKFGNLNNVYSLEKRFFERFPQE------NLIEVFTSRYQIQNSNLIKKLELTYMYNEEEDSYFSSGNGDGHHGSYNM---------------------------SSSDRKRLMEETGNNGNFSNKKFKRDSELPTEVLDLLSVIPKRQYFNTNLLDAQKLVNFLNDQEIPTVESTKS............................................................................. 676
3 -73.400[A] KOG1258 mRNA processing protein  ali follow..  15  10.EETEWDKYNRQINKNPDDFDAWEGLVRASEHQAINTLRSVYDRFLGKYPLLFGYWKKYADFEFFVAGAEASEHIYERGIAGIPSVDLWTNYCAFKMETNG----DANEVRELFMQGANMVGLDFLSHPFWDKYLEFE---------ERQERPDNVFQLLERLIHIPLHQYARYFERFVQVSQSQPIQQRARIYNIHLQIFQKVQLETAKRWTFESEIKRPYFHVKEL----DEAQLVNWRKYLDFE--------EVEGDFQRICHLYERCLITCALYDEFWFRYARWMSAQPDHLN-------------DVSIIYERASCIFAISRPGIRVQYALFEESQGNIASAKAIYQSILTQL-PGNLEAVLGWVGLERRNYDLTNAHAVLRSIINEGKCNTGLITEDIKLVWKIEGDIELARNMFLQNAPALLDCRHFWISFLRFELEQPHHARVSNVMEMIRNKTRLPPRTIMDLTKLYMEYLCHQSNDPSVLQEYLLIDRDVFGPFSVRESHWKKLDEGQDLKQVSTRLLSTNGHPGISVNEAKIKSGESPYEKYYRLQGVVETVTSGVAANGSS.................................................................................................................................................................. 612
4 -67.800[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali follow..  12  18.LDEEIQKIKQKMIDDSQSVVLANQLLILLRKGDFDELDIKRRQFVEWAPLNPLNWKNWIEDFQNRPSVAEVEEMFEKALFDENDVTIWVERAMYAYKVANDKKEDFKFCRDVCSKALENLGTRYSGGHIWLIFLEYEMSYLKNNAPDYQRLADQVFALFERALHCPTDQLEDVYVLAEQFCTEFKQ---HHKLEELKKTYNSTMRQKEQLSKFEELIQQ------------EETKKQGLKQFFDHEKKS--------GIPSRIKMAHERLVSELDDDEEAWIAYGAWADIELKLPQ-------------VAVKVYSRALRHCPYSFVLHQQALLAFERDRRPNEEIDALWERARSNSAEEGRSLYRTYAFLLRRRSDYSPMAEVFDEGAAAWDTTADYRQMQAYFYASLMKNMDKCRNIWNDILASFGRFAGKWIEAVRLERQFGDKENARKYLNKALNSVS---DNINEIYMYYVQFEREEGTLAELDLVLEKVNSQVAHRAIRPQKKVSEKPAPAPKSKQDHIQKRTSGGEPIVKKVKGDDGGFKAPLPPSNAKSSSAVSSSNASSTPAPGSFAVQKAAPGT-----------------------------EDARTIFVSNLD----FTTTEDEIRQAIE-IRFARKANSD-LVHRGFAYVVMENDQKAQQALLKDRVPVKGRPMFISANDPEKRVGFKFSTTLEKSKNVHFQATDDELKALFSK....... 705
5 -49.800[D] KOG1915 Cell cycle control protein (crooked neck)  ali follow..  12  39ITAEQILR-EARERQEAEFRPPNQTITDSAELDYRLRRRKEFEDQIRRARLNTQVWVKYADFEMKNKSVNEARNVWDRAVSLLPVDQLWYKFIHMEEKL-----GNIAGARQILERWIHCS----PDQQAWLCFIKFE---------LKYNEIECARSIYERFVLCHPK--VSAYIRYAKFEMKHGQELAMKVFERAKKELADDEEAEILFVAFAEFEEQYK---FALDQIPKGRAENLYSKFVAFEKQNGDKEGIEDAIIGKRRCQYEDEVRKNPLNYDSWFDFVRLEETVGNKDRIREIYERAVANVESTRDVYRACLKLIPHSKFSIWLLAAQHEIRQLNLTGARQILGNAIGKAPKD--KIFKKYIEIELQLRNIDRCRKLYERYLEWSPGNCYAWRKYAEFEMS-LAETERTRAIFELAISQPALDELLWKTYIDFEISEGELERTRALYERLLDRTKHCKEERAMLLEDWLNMETGFGKLGDVRVVQSKLPKKVKKRKLSSREDGCTEYEEYTDYLFPEESETTSLKILEAAHKWKKQKVKAGE......................................................................................................................................................................................... 655
6 -48.400[A] KOG2047 mRNA splicing factor  ali follow..  15  10..SQEDLLYEEELLRNQFSLKLWWRYLIAKAESPFKKRFIIYERALKALPGSYKLWYAYLNLPVTHPQYDSLNNTFERGLVTMHMPRIWVMYLQTLTVQ-----QLITRTRRTFDRALCALPVT-QHDRIWEPYLVFVSQTSLADYYIRKNLLEKARDIYEEGMMKTVRDFSVIFDVYSRFEESTVAKKMEMMSSSDEEDENDDNDVDLRLARLEELMNRRPALANSVLLRQNPHNVEQWHRRVKIFEGNA----------AKQILTYTEAVKAVGKPHTLWVAFAKLYENHKDLVNTRVIFDKAVQVNYKTVD-----------HLASVWCEWAEMELRHKNFKGALELMRRATAVPTHRSLRLWSFYVDLEESLGTLESTRAVYEKILDLRIATPQIIMNYAFLLEE-NKYFEDAFKVYERGVKIFPHVKDIWVTYLTKFVKRTKLERARELFEHAVSM--APSDAVRTLYLQYAKLEEDYGLAKRAMKVYEEATKKVPEGQK...................................................................................................................................................................................................................................... 659
7 -38.500[A] KOG0495 HAT repeat protein  ali follow..  12  282..KKARLLLKSVRETNPNHPPAWIASARLEEVGKVQMARNLIMRGCEMNIQSEDLWLEAARLQ----PPDTAKAVIAQAARHIPSVRIWIKAADL--------ESETKAKRRVFRKALEHIP---NSVRLWKAAVELENPDDARI---SRAVECCNTSVLNKARENIPTD-RQIWTTAAKLEEANGNIHMVEKIIDRSLTSLTVNGVEINRDQWFQNCCQSIVKAVIGIGVEEEDRKQTWIDD--------AEFCAKENAFECARAVYAHALQIFPSKKSIWLRAAYFEKNHGTRESLEALLQRAVAHCPAARGILSLAFQ-ANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPTP--RVMMKSARLEWALEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQ-QRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNP----KVAVLWLEAIRVELRAGLKEIASTMMARALQECPNAGE...................................................................................................................................................................................................................................... 784
8 -34.400[R] KOG2396 HAT (Half-A-TPR) repeat-containing protein  ali follow..  13  1MADVVQYRLERMVDE---DLER-REIFTRAEIAEIVKQRRKFEYRLKRPSPLKEDFIAYIDYEVKLDELARIVEIYRLATMRYKDINLWFRYLEFCKQ------KRHGRMKKALAQAIRFHP---KVAGVWIYAASWEF--------DRNLNVTAARALMLNGLRV-CSNSEDLWVEYLRMELTFLNKLKARKVNVLQTIYSGAVEAIPSSFDLRKRFLEILEATDLAHSDEMRNTIEYWNWLARHEMSG-AGLEFANPQMQKAIQVFEEGLQTVT-SSSMFEIYINFLMEAIVQSNGDENEISSLSIISHIINVYQKADET---LTEELADEYVSLYLKLEKTHEAQKLAEKLCSEKFAGSAKLWLSRVSIEIRSADFQTVFELLSNALRKVPISESESLWLMAFNFFAHKGAHSARKIYKRFLALPGPSLVLYKGCIEIETNLIGLSNARKLYDSAVASYGQDVE----LWKNYYSLETKLGTSETANGVYWRARKTLNESAD...................................................................................................................................................................................................................................... 645
9 -31.100[R] KOG1124 FOG: TPR repeat  ali follow..  13  154..AAAARAQERPLAVNL---DLSLYKAKVLRNFRYKDAEKILEKCIAYWPEDGRPYVALGKILSKQSKLAEARILYEKGCQSTQNSYIWQCWAVLENRL-----GNVRRARELFDAATV---ADKKHVAAWHGWANLE---------IKQGNISKARNLLAKGLKFCGRN-EYIYQTLALLEAKAGR-------------YEQARYLFKQ------------------ATICNSRSCASWLAW---------QLEIQQERYPAARKLFEKAVQASPKNRFAWHVWGVFEAGVGNVERGRKLLKIGHALNPRDPVLLQS---------------LGLLEYKHSSANLARALLRRASE-LDPRHQPVWIAWGWMEWKEGNTTTARELYQRALSNTESASRCLQAWGVLEQR-AGNLSAARRLFRSSLNINSQSYVTWMTWAQLEEDQGDTERAEEIRNLYFQQRTEVVDDASWVTGFLDIIDPALDTVKRLLNFGQN................................................................................................................................................................................................................................................ 575
10 -25.400[R] COG5191 Uncharacterized conserved protein, contains HAT (Half-A-TPR) repeat  ali follow..  10  1MAEKVQYYMEQSVPE--------KNIFNRDEINNIIKTRRVFEEKLARRQVKLNDFLSYIQYEINLETLRKVLFLFLRATNKFFDVTLWLDYIHYAQKI-----KAVNIVGKICVAALQ---KHPNNAELWVVACDHEF--------SINANVSAARALMNRALRL---ENPVIWAAYFRLELSYMTKLFARSQILTGNISSKTENITNGVSE-------------------------------TIGSLSSDTIQLPMVSMEEFLGSSSSEVRKNDSDLNISDDIGNISSKEQQTQKFANVLLQI---------ILNSRKNLSLQNYVGFFVSVLDALFECFDVPVVQYMYQENIIGICNEHFEHFKNESGEIYGVAYPSNDSGISGKGIFGLKKNDPRITSMVLTDPGFVDDLQAIVEKYQSISSDFKTKKIFYSFFVKTLHAISSSSAAESSIALALHMLVINAKLKILTFDDSLQEIYKEAQIQSGTFMSNATLS............................................................................................................................................................................................................................................. 488
11 -17.900[T] KOG4162 Predicted calmodulin-binding protein  ali follow..  357LIAEALAVRDTVLSQSPEFRQARQHAMGTVRWGLVQLLNESFEKALKFSFGEQHVWRQYGLSLMAAEKHSHALRVLQESMKLTPSPLPCLLASRLCYESLETVKQGLDYAQQALK--REVKGLRPSRSQLFVGIGHQQLAIQSNLKSERDACHKLALDALERAVQFDGNDHLAEYYLSLQYALLGQLAEALVHIRFALALRMEHAPCLHLFALLLTSSRR----------------------------------------PREALGVVEDALHEFPDNLQLLHVKAHLQLHLEDAETALGTVQHMLAVWRDVYEAQLAGEEEKHSDTSVYAASLAAVSRVEQALSEAASSLSSFTQRPWMLQIEIWLLLADVYLRIDQPNEALNCIHEASQIYPLSHQIMFMRGQVHVYL-EQWFDAKQCFLNAVAANPNHTEALRALGEAHLVLGEPRLAEKMLKDAAKLDPSCPK----IWFALGKVMEILGDFHASADCFATSLQLEPS......................................................................................................................................................................................................................................... 847
12 -17.500[U] KOG0547 Translocase of outer mitochondrial membrane complex, subunit TOM70/TOM72  ali follow..  144..NEAIKYYQYAIELDPNEPVFYSNIACYISTGDLEKVIEFTTKALEIKPDHSKALLRRASANESLGNFTDAMFDLSVLSLNGDFDGASIEPMLERNLNKQAMKVLNENLSKDEGRGSQVLPSNTSL----ASFFGIFDSHLEVSSVNTSSNYDTAYALLSDALQRLYSATDEGY------------LVANDLLTKSTDMYHSLLSANTVDDPLRENAALALCYT--FLKNNLLDAQVLLQESINLHPTPNSYIFADKENSQEFFKFFQKAVDLNPEYPPTYYHRGQMYFILQDYKNAKEDFQKAQSLNPENVYPYIQL---------------ACLLYKQGKFTESEAFFNETKLK-FPTLPEVPTFFAEILTDRGDFDTAIKQYDIAKRLEEVQEKIHVGIGPLIGKAEEKFNAAIKLLTKACELDPRSEQAKIGLAQLKLQMEKIDEAIELFEDSAILARTMDEKLQATTFAEAKIQKRLRADPIISAKMELTLARYRA......................................................................................................................................................................................................................................... 635
13 -16.700[DO] KOG1174 Anaphase-promoting complex (APC), subunit 7  ali follow..  28....TMSNNNPELFSPPQKYQLLVYH-SLFHDKEYRNAVSKYTMALQQ-PSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGR-----ERPSVTSYKEVLR---QCPLALDAILGLLSLEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQM------------LDLYLIKGMDVY---------YLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQAL---------------LLKGAALRNMGRVQEAIIHFREAIR-LAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALAN-----QSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKS..................................................................................................................................................................................................................................... 511
14 -16.400[R] KOG1129 TPR repeat-containing protein  ali follow..  10..VDELENEDMGLAEDQNVIAPNARPTSFARPKTSAKGVNPILRPTTN-AGRPLSGVVRPQSSFKSGSMDQAVRTARTAKTARAVSS--TSARNMRLGTASMAAGADGEFVNLARLNIDKYAADPQVNRQLFEYV------------YYLNDIRVAHQIAGTASKA-KNQLAKCYLRLGMLQDATKQLQSSLEQKKLIETFALLSKAYNRVDQPMAAL-------------------KTYSAGLEVFPENVTRVQEALGEYDESVKLYKRVLDAESNNIEAIACVATTYYYGGKPELAMRYYRRILQMGVSSPELFLNIGLCC---------------MAAQQFDFALSSILRAQSTMTDDAADVWYNIGQILVDIGDLVSAARSFRIALSHDPDHSESLVNLGILKHR-EGKIDEARSLYSSATSKNPYMFEGNYNLGLVSFTQGKYHECRELIEKALA-----------AFPEHEHCKKILNHLKPLYES................................................................................................................................................................................................................................................... 457
15 -16.200[B] KOG1156 N-terminal acetyltransferase  ali follow..  10  2..........PAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSKFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRDLKSHVCWHVYGLLQRSDKK------DEAIKCYRNALK---WDKDNLQILRD----------SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEE----FRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGCRLEDAADVYRGLQERNPENWAYYKGLEKAL-KPANMLERLKIYEEAWTKYPRGLVPFKECLDKFLPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHA-GNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTEKAMNKFGEALKKCHEIERHFIEITDDQSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLKNLV................................................................................................ 668
16 -15.500[DO] KOG1155 Anaphase-promoting complex (APC), Cdc23 subunit  ali follow..  109..RRASHMLRDQVSKKSLFLRYYALYLAGEKRRELVSLERDLSALRRTGAIDSFGLYLYGVVLKEKGNESLARASLVESVNSYPW--NWSAWSELQSLCTSIEILNSLNLNN-----------------------HWMKEFFLGNAYQELRMHTESLAKYEYLQGIFSFSNYIQAQTAKAQYSLREFDQVEIMFEELLRNDPYRVEDMDLYSNVLYAKEA----------------------------------------CAALSYLAHKVFLTDKYRPESCCIIGNYYSLKGQHEKAVMYFRRALKLNKKYLSAWTLMGHEYV---------------EMKNTPAAIDAYRRAVD-INPTDYRAWYGLGQAYEMMGMPFYALHYFRKSIFFLPNDSRLWIAMAKYQTEQLYMLEEAIKCYKRAVNCTDTEGIALNQLAKLHQKLGRNEEAAYYFEKDLERMDAEGLEGPNMFEALVTHFKNHKKFEEAEVYCTRLLDYSGPEKEK..................................................................................................................................................................................................................................... 554
17 -15.300[D] KOG1126 DNA-binding cell division cycle control protein  ali follow..  19..DNSIFYSERLHAIEDSNESLYLLAYSHFLNLDYNIVYDLLDRVISHVPCTY-----FARTSLILGRYKQGISAVEACRSNWRSIQ--ASCMLDVLGTMYKKAGFLKKATDCFVEAVS---INPYNFSAFQNLTAIGVPLDANNVFVSNSSISAFTKWFDRVDASELPGSEKERHQSLKLQSQSQTSKNLLAFNDAQKADSNNRDTSLKSHFVEPRTQALRPGARLTYKLREARSSKRGESTPQSFREEDNNLMEAQYKLREALNCFQSLPIEQQNTPFVLAKLGITYFELVDYEKSEEVFQKLRDLSPSRVKDME---------------VFSTALWHLQKSVPLSYLAHETLE-TNPYSPESWCILANCFSLQREHSQALKCINRAIQLDPTFEYAYTLQGHEHSAN-EEYEKSKTSFRKAIRVNVRHYNAWYGLGMVYLKTGRNDQADFHFQRAAEINPNNSVLITCIGMIY----ERCKDYKKALDFYD................................................................................................................................................................................................................................................. 557
18 -15.100[R] KOG1128 Uncharacterized conserved protein, contains TPR repeats  ali follow..  130.....................VWQQLLIDPEETIRTEIEPIMEKLRVLIEDRCQIQLEMAAVRFQFYEYDKADNLIKSASEECQNMDLSIAQLVLIHKDPSTTGTPLPPDSDI-DTLLEQVAIDGRTLNACQLSCLLWIARHESATHRHDVLVHERCSPVLDTVIAARRY----WSIQAA------------ALLARAELERGRVRQVDRSCTQSELVVKLQQGVDDPVLIKDRLLRTSYILASGLTPFWQSSVLNSLGCTSEALLILEKL--------EMWDGVIDCYKQLGQMDKAETLIRRLIEQKPNDSMLH-----------------------YLGDITRNLEYFTKAIELSDDRNARAHRSLGHLLLMDKKFEEAYKHLRRSLELQPIQLGTWFNAGYCAWKL-ENFKESTQCYHRCVSLQPDHFEAWNNLSAAYIRHGQKPKAWKLLQEALKYNYEHPN----VWENYMLLSVDVGEFSQAIQAYHRLLDMNKR......................................................................................................................................................................................................................................... 601
19 -14.700[O] KOG0548 Molecular co-chaperone STI1  ali follow..  19..TTAINHFTEAIALAPTNHVLFSNRAAHASLHQYAEALSDAKETIKLKPYWPKGYSRLGAAHLGLNQFELAVTAYKKGLDVDPT-----EALKSGLADAEASVARSRAAPNPFGDAFQGPEMWTKLTS--------DPSTRGFLQQPDFVNMMQEIQKNPSSLNLYLKDQRVMQSLGVLLNVKFRPPPPQGDEAEVPESDMGQSSSNEPEVEKKREPEPEPEPEVTEEKEKKERKEKA-------KEKELGNAAYKKKDFETAIQHYSTAIEIDDEDISYLTNRAAVYLEMGKYNECIEDCNKAVERGRELRSDYKMVARALTRKGTALTKMAKCSKDRLNDAERAKKEWEQKQY-FDPKLGDEEREKGNDFFKEQKYPEAIKHYTEAIKRNPNDHKAYSNRAASYTKL-GAMPEGLKDAEKCIELDPTFSKGYSRKAAVQFFLKEYDNAMETYQAGLEHDPSNQEGVKRCVQQINKANRGDLTPEELKERQAK................................................................................................................................................................................................................................................ 517
20 -14.700[U] KOG2376 Signal recognition particle, subunit Srp72  ali follow..  2....APKSKENPKTSTPAIEDLFTSLHKHIKDTKYEEAVKVADQVLSIVPTDEDAIRCKVVALIKDDKFDDYLIKDVKINGALSVINFHKAYCLYRENKLDEALVCLKGLERLEAQILNCLGKVDACVDVYQKLNKSGIKLIEVNLVAALIRAGKASQVLESLKIRPTTTYQLAYN--------------TACSLIENSNYVDAEQLLLTAMRIGQETLTEG-DYSDDYIETQLAPISVQLAYV-----------QVLGQTQESKSSYVDIIKRNLADESLALAVNNLLKGSKDISDGLRKFDLLKDKDSQNFQLSQELDAKLSHHKEAIYANRVLLLLHANKMDQARELCATLPGM-FPESVIPTLLQAAVLVRENKAAKAEELLGQCAENFPEKSKLVLLARAQIAASASHPHVAAESLSK-IPDIQHLPATVATIVALRERAGDNDGATAVLDSAIRDSMTDSNMLRILMPVAAAFKLRHGQEEEASRLYEEIVKNHNSTDALVGLVTTLARVNVEKAEAY----EKQLKPLPGLKAVDVDNLEKTSGAKPIEGISAASLSQEEVKKEKVKRKRKPKYPKGFDLENSGPTPDPER--------------------------LPRRE------------------------------------------RSSYRPKRKDKRAAQIRGSQGALTKVKQEEAPSTSKSKQAAISKANAAGPSSSKASKKKSRR.. 651
21 -14.500[DO] KOG1173 Anaphase-promoting complex (APC), Cdc16 subunit  ali follow..  1MPGDT-ENTSTDTTNEHIDLALYRQLVKFIDMRRYSTALFWAEKVAVLGGLEPRDIYYQAQCMYLLGEYHRAAHTFTEAANVIQNVEV-LSSIYLMKGKVYEALDNRGMAMDFYVQALH---KSIYCFEALEALVQHEMLMAWEAQQSSEADAKFILKLYESRL-----------KKYYELISARNAEEMSPIVNQFIKEFTARVQQSGSSDTQMPKVSAVKVPLTPSQFMSPAQKVLEDLKAPTFSLQTSLSKASSRDHDTDTLIPIAECLDRVQRSTDLMAAEAEKCFYDCDYKQCLKILNELLKVDPRLFYVAHKLVD-RYPDKAISWYAVGCYYDMIGKSDPARRYLSKATA-LDRLYGPAWLAYGHSFANENEHEQAMAAYFKATQLMRGCHLPLLYIG-VECGLTKNLELAEKFFLQAMNIAPLDVYVLHELGVIKYEYEFFDGAATIFQCTVDIVKQRAKSNEPLFINLGHSLRKVHKYEEALYNFQYALLLKPQSPT...................................................................................................................................................................................................................................... 609
22 -13.900[S] KOG4340 Uncharacterized conserved protein  ali follow..  23....RDARYAEAVQLHPELEQYRLYQAQALKACLYPEATRVAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSLVEQLLSGEGGE------GQVNLGCLLYKEGQYEAACSKFSATLQASGYQPDL------------SYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGFDVRSVGNTLVLHQTALVEAFNLKAAIEYQLRNYEVAQETLTDMPPRAEEELDPVTLHNQAL-----------NMDARPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTEEAFIKLDGLAGMLTEQLRRLTKQVARHNRDDEAIKKAVNEYDETM----EKYIPVLMAQAKIYWNLENYPMVEKVFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKHYDNAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPNVNLVIGTLYCAKGNYEFGISRVIKSLEPYNK......................................................................................................................................................................................................................................... 539
23 -12.700[S] KOG4507 Uncharacterized conserved protein, contains TPR repeats  ali follow..  213......HLIHEGLQKNTSSWVLYNMAFYWRIKNEPYQVVECAMRALHFSSRHNK-LVNLANVLHRAHFSADAAVVVHAALDDSDFFT-----SYYTLGNIYAMLGEYNHSVLCYDHALQA---------------GFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCRWDQPVRYHRGDIFENVDYVQFGEDSSTSSMMSVNFDVQSNQSDINDILWPKRADCTESYPRVPVGGELPTYFLPPENKGLRIHELSSDDYSTEEEA---SITDFRKSHTLSYLVKELEVRMLKAKMPDDHARKILLSRINNYTIPEEEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQ-LVNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLA----LKNISGALEAFRQALKLTTKCPECENSLKLIRCMQFYPFLYNITSSVCSGNCHEKTLDNSRDKQKYFDNSQSLDAAEEEPSERGTEEDPVFSVENSGRDSDALRLESTVVEESNGSDEMENSDETKMSEEILA-QQAWPLEGFGGALEMKGRRLDLQGI-RVLKKGPQDGVARSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKTPGKKVETGQIENGHRYQANLEITGPKVASPGPQD-WKTRK..... 954
24 -11.900[Z] KOG1840 Kinesin light chain  ali follow..  84...EFDVKSNSSNLDLEVMPRDMEKQTGKKNTKSNVGVGGMRKKKVGG--LARFLLNQARNLVSSGDSTHKALELTHRAAKLFPCLEWIMCLTAAVHCKLKEYNEAIPVLQRSVEIPVVEEGEE-------HALAKFAGLMQLGDTYAMVGQLESSISCYTEGLNI-CRYLAEALVQALRFDEAQQVCETALSIHREAADRRLMGLICETKGDHENALEHLVLASMAMAANGQESEVAFVDTSIGDSYLSLSRFDEAICAYQKSLTALKTAKENHPAVGSVYIRLADLYNRTGKVREAKSYCENALRIYESHNEISPEEIASGLTDISVICESMNEVEQAITLLQKALKIYADSIAGIEAQMGVLYYMMGKYMESYNTFKSAISKLRATGKKQSTFFGIALNQMGLACIQLDAIEEAVELFEEAKCYHPETLGLYSNLAGAYDAIGRLDDAIKLLGHVVEKLGTANPVTEDEKRRLAQLLKEAGNVTGRKAKSLKTLIDSDL......................................................................................................................................................................................................................................... 643
25 -11.400[O] KOG0530 Protein farnesyltransferase, alpha subunit/protein geranylgeranyltransferase type I, alpha subunit  ali follow..  14  59.SDRVMALLEDCIRLNPANYTVWQVCLTELGW-DLKKEMRYLSDIIQESPKNYQVWRRFIVETIGESAVNDELHFCSEVIRDENNYHAW-QHRQWVVRTFKVPLE------KELTFALHMLLLDNRNNSAYNY-------MTLYDKTEDASQLDIEINLAKKFIENIPNN-ESAWNYLAGLLITNGVTSNSDVVSFVEDLY-----------------------------ETTPEEKRSPFLIADMMLENIENQKSAEESAGRAKKLYKDLQSIDPVRVNYYRHQSLLAQTMLIKAQTKVTAK................................................................................................................................................................................................................................................................................................................................................................................................................................................ 328
26 -11.300[V] KOG0624 dsRNA-activated protein kinase inhibitor P58, contains TPR and DnaJ domains  ali follow..  9..ILWSSLFASTFAGTAEEVAKHLE--QFLARAQFADALTQYHAAIELDPKSYQAIYRRATTYLAMGRGKAAIVDLERVLELKPD-------ARIQRGNILLKQGELEAAEADFNIVLNHDSSNNDVQEKTALIEQHRQLRHQIKSAYAGGDCATVEEYINHIIEIQVWDAS---------------------------LYRMRAKCLEERGELKKAIHD-----------------------------------------------MRIVSKLSTDSTDTMFETSKLLYTVGDLEESLNVIRECLKLNPDHKSCYPFYKKLRKVVKSL-----MKKKVENSDWMACLEEGQKTMKFDPTPQLNVFRITNRCQREAGHISEAIAECNEILNDDPSDADILCERAEAHILD-EDYDSAIEDYQKATEVNPDHREAKEGL---HAKRLKTQAGKRDYYKILGVKRNASKREITKAYRKLWHPDNFSDEEEKKKAEKKFIDIAAAKEVLQDEEKRRQFDQ.......................................................................................................................................................................................................................... 445
27 -11.300[O] COG4235 Cytochrome c biogenesis factor  ali follow..  13  76..SRLALGMRTQLQKNPGDIEGWIML-VGMALGNASIATDAYATAYRLDPKNSDAALGYAEALTRSSDNRLGGELLRQLVRTDHS-------VLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIERSIAQAMQHLSPQESK........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 221
28 -11.200[R] COG0457 FOG: TPR repeat  ali follow..  10  413LMRKSLKDYQDQ-EVHNFMLDFYSNQLKDIDKEITPEHEIALTEAFYHAEDLLKWFISVSDPFNRAAFWQLITPMYEEMLQILEAK-HGPEHKDIVTTLNILKMGEYKKALQFSERALA-----IGETILGVQHPDVATSLDNAGLYESMGNYKQALQLSERALEI-----KVLGPQHRDVAITLDNL---AGLYESMGEYEKALIFYQRTIEIKEKVLGPQHSNFATSLDN-----------LAVLYRQMGEYEKALQLSQRALEIYEKVL---PQHPDI--NIALLYDSMGDYQKTLPLYQRALEINEKVFGPQYLGIATTLNNLAGFYRRVGDYEKALSLSQRSLEIDEKVLGSQHPDVARTLNSLALIYENIGDYEKALAFYQRSLDIREPDVGRTLNNLARLYEIMGDHEKALTLYQRTIEQHPDVATILNNLAGLHYRIGEYKKALPLYQRALDI------VEKKLGQNQPNSVVIKNNYNRLLSKMSENEKK............................................................................................................................................................................................................................................ 914
29 -11.000[O] COG5536 Protein prenyltransferase, alpha subunit  ali follow..  14  58.SLRALNLTGFLIMNNPAHYTVWAQILNHTPS-YIDNELEWLDEIAEDFQKNYQVWHHRQKILSLTKNYERELEFTKKMFEIDSNYHVW-SYRVWILQNFNDYSQELKLTNELLE-------KDIYNNSAWNHRFYVLFETSKVVSWSLEEELN----YLKDKILFAPDN-QSAWNYLCGVLDKSGPSKLDNLIANLRKNLPALHKPLLEFLAMYEPSSSEEI-YQKLANEVDVPHAALWT.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 286
30 -11.000[U] COG5010 Flp pilus assembly protein TadD, contains TPR repeats  ali follow..  13  60..AAAAERIGQAYERNPKDREAGLNYANLLRMGRNEQALAVMQQVAIYHPADREVLGAYGKAQAAAGQLEQALATISRAQTPDRP-------LKSAEGAILDQLGRSAEARLRYREALD---LKPNEPSVLSNL---------GMSYLLTKDLRTAETYLKSAASQP-QNLALAVGLQGRFQEAETIAGQELTSEQAEANVAYLRSVLSQQGAWKQLAKAD.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 269
31 -10.900[NU] COG3063 Tfp pilus assembly protein PilF  ali follow..  10  21.......................................................................................................................................................................................................................................................................STSYRPSRAEKANQVSNIKTQLAMEYMRGQDYRQATASIEDALKSDPKNELAW---------------LVRAEIYQYLKVNDKAQESFRQALS-IKPDSAEINNNY--LCGRLNRPAESMAYFDKALADPPTPYIANLNKGICSAKQ-GQFGLAEAYLKRSLAAQPQFPPAFKELARTKMLAGQLGDADYYFKKYQSRVEVLQADDLLL----WKIAKALGNAQAAYEYEAQLQANFPYSEELQTVLTGQ.............................................................................................................................................................................................................................. 253
32 -10.600[R] KOG4197 FOG: PPR repeat  ali follow..  58........ITRGVAPNPTFQKKLFVFWCSRLGGHVSYAYKLFVKIPEPDVVV---WNNMIKGWSKVDCDGEGVRLYLNMLKE-PDSHTFPFLLNGLKRDGGALACGKDMARGVFDR------RCKEDVFSWNLMI---------SGYNRMKEYEESIELLVEMERNLVSPTSVTLLLVLSACSKVKDKDLCKRVHEYVSECKTEPSLRLENALVNAYAACGEMDAVRIFRSMKARDVISWTSIVK----------VERGNLKLARTYFDQMPVRDRIS---WTIMIDGYLRAGCFNESLEIFREHLGSLEIGEWIKTYIDKNKIKNDVVVGNALIDMYFKCGCSEKAQKVFHDM----DQRDKFTWTAMVVGLANNGQGQEAIKVFFQMQDMSIQPDDITYLGVLSACNHSGMVDQARKFFAKMRSDHRIEPSLYGCMVDMLGRAGLVKEAYEILRK------MPMNPNSIVWGALLGASRLHNDEPMAELAAKKILELEPDN........................................................................................................................................................................................................................................ 570
33 -10.400[O] KOG0550 Molecular chaperone (DnaJ superfamily)  ali follow..  2...............................TEVETTHMNAGTESQQEPAELAEKQKAIGNAFYKEKKYAEAIKAYTEAIDLGSDSALAIYYSNRAATYMQIGE---------FELALC----------------------------------------AKQSDRIKPDVPKTQ------------------------SRIRQAYEGLSILNEAEVYLKNKQAGLALNALDRLQRRIDSTTQPPMSWMYLKAQVYIFQNDMDRAQKIAHDVLRLNPKNVEALVLRGKVMYYSGENAKAITHFQEALKLDPDCTTAKTLFKQV---RKLENTKNQGNDLFRQGNYQDAYEKYSEALQIDPDNVAKLYMNRATVLLRLKRPEEALSDSDNALAIDSSYLKGLKVRAKAHEAL-EKWEEAVRDVQSAIELDASDANLRQELRRLQLELKKSKRKDHYKILGVSKEATDIEIKKAYRKLALVHPDKNAGNLEAEARFKEVGEAYTILSDPESRRRFDSGVD.......................................................................................................................................................................................................................... 415
34 -10.100[R] KOG1125 TPR repeat-containing protein  ali follow..  11  343..PVTILFMEAAILQDPGDAEAWQFLITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKEGVKELYLEAAHQNGDMIDPDLNRAIDAFNAALT---VRPEDYSLWNRL----------ATLANGDRSEEAVEAYTRALEIQPGFIRSRYN--------------------LGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAA-LRIALSLMDQPELFQAANLGDLDVLLRAF............................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 622
35 -10.000[TDBLU] COG5032 Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family  ali follow..  1398..ARALFYWEQHIRNATAPYAALESDYRVLQEDDPDEIEAVFDQQLLLHENSGT-WDSALSYEIIIQKDPENKKAKIGLLNSMLQSGHYESLVLSLDSFIINDNHEYSKMLNLGIEASWRSL--------IDSLKKCLSKSNLESFEAKLGSI--FYQYLRK----------DSFAELTERLQPLYVDAATAIANTGAHSAYDCYDILSKLHAIND-------RIAETDGIVSDNLDIVLRRRLSQVAPYGKFKHQ------STHLVGYEKFENTKKTAEIYLEIARISRKNGQFQRAFNAILKAMDL-----------------DKPLATIEHAQWWWHQGQHRKAISELNFSLNNNMFDKGKVFLKLTKWLGKAGGLKDLETYYHKAVEIYSECENTHYYLGHHRVLMYEEEQKIINEFGRSLESMPKLLTLWLDFGAEELRLSKDDGEKYFREHIISSRKKSLELMNSNVCRLSMFLVALSQMISLEHIIANVVASYPGETQLMATIKSTSQKRSLRGKSILNVLHSRKLSMSSKVDIKALSQSAILITEK..................................................................................................................................................................................... 1985
36 -9.970[G] COG2956 Predicted N-acetylglucosaminyl transferase  ali follow..  20....GRRSAQQNKQDEANRLSRDYVAVNFLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMES------------------------ASLTYEQRLLAIQQLGRDY----------------------MAAGLYDRAEDMFNQLTDETDFRIG---------------------------ALQQLLQIYQATSEWQKAIDVAERLVKLGKDKQRVEIAHFYCEL---------LQHMASDDLDRAMTLLKKGAAADKNSARVSIMMGRVFMAKGEYAKAVESLQRVISQDRELVS--------------ETLEMLQTCYQQLGKTAEWAEFLQRAVEENTG--ADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEGRAKESLMVLRDMVGEKVRSKPRY............................................................................................................................................................................................................................................................................................................ 355
37 -9.950[S] KOG4648 Uncharacterized conserved protein, contains LRR repeats  ali follow..  10  116..SQESESEEDGIHVDSQKALVLKE--KYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVA------------------------NRSYTKAYSRRGAAR---------------------------FALQKLEEAKKDYERVLELEPNNFEKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFK-----EGKYERAIECYTRGIAADGANALLPANRAQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEK-----GHWDDVFLDSTQRQNVVKPI--DNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATG-TTSKKNSSQDVLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKP--ANSFQLESDFRQLKSSPDMLYQYLKQIE.......................................................................................................................................................................................................................................... 574
38 -9.710[S] KOG3060 Uncharacterized conserved protein  ali follow..  10  68..DIATKCTKQLSLEFPGSLRVMKFKMRYEALEQYDEADEVLDAIIAKDETNAAPRKRKIAILKARGRRLEAIKELNEYLKKFMDQEAWHELCNMYLAEGE-----FGKAAFCMEEVLL---HNPHSHLIHQRLAEIRYTM------GGVENMESARTYYSQALKLNPHNLRALYNHLDNSRAVSSKRKELQKLSQWALEQLLTKQTIVPLEAAFGNLE.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 278
39 -9.630[S] COG3898 Uncharacterized membrane-bound protein  ali follow..  58...........................................................................................................................................................LWWLIRSLWNSP--------YTISRYFRVRRRDRGYQALSTGAGDGALARKKTKEAAKLIRSDQEPLIHLLEAQASLLEGDHEGARQKFESMLDDPYLEAERLGDRNAARHYAGRAAAVAPQLAWAAESTLEELTARGDWDGALKLVDAQKSTRQIERDAANRRRAVL--------LTAKAQSLADSDPNAARTAALEANK-LQPDFAPAAVAAAAALFKQNDVRKGSKILETAWRAEPHP----IAELYTHARPGDAVLDRLNRAKKLQEMKKNHAESSMTVARAALDAQDFSTARSEAEAAIRMDR----REGAYLLLADIEEAETGDQGKVRQLLSKAVRAPRDPAWVADGVVSERWAPVSPVTGRLDA-RAPMERLGQLIDSRDEGTTVPVIEALAKPASEKPIDAIEPVAAGSETTGKGTDRSEDQVTPVTAAAFAAVPADAEAVEPAEELTRLPDD--------PGVDP-DEEAEKSPRRFRLF.......................................................................................... 531
40 -9.060[S] COG1747 Uncharacterized N-terminal domain of the transcription elongation factor GreA  ali follow..  83...QIVEHLCTRVLEYGESKLALRALGECYKTSGNEQLYDVWERLVRIDYEEAEITRVLADKYEQEGNKEKATEFYKKALYRFIARRQNAAIKEVWTKLVALIPDDVEFFYREQK-KISEKLGEGRGSVLMQDVYVY---------YKENEDWTTCINILKHILEHDEKDIIENFRCKYRGHSQLEEYLKISNISQSWRNVFEAINDFEKHISFDAKVCNDELLIDFAKRRAHTMLLKMAISALQTLGKEHIWVLKSVLKRQDLAAKVKQELVPSLLSVGEWTSWSTKARKILKESDFYTVRSCPVSLEEKLAVEFKAQ-KNFFARIDILNTFMDKADTDSDAFREMFDYFNTFLRAFSVVDGNVIAAYLVVTRVSTVLPHLNAGFADLYAHIADPRLVYTEIKDKGLKVKNFVSNWSDEYVKLFPEVLSL-----EILRALMEEGYKEKALRVVEACFEYYADNRA----IW...................................................................................................................................................................................................................................................................... 599

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.