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Query: [R] KOG2140 Uncharacterized conserved protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDTDSNTDQDAGSSEEDEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQKLast
1 -128.000[R] KOG2140 Uncharacterized conserved protein  ali  100  1MKSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDTDSNTDQDAGSSEEDEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
2 -75.000[T] KOG2141 Protein involved in high osmolarity signaling pathway  ali follow..  10  171.QKKERDGKLKVPKSMKSDGLDLLLDFCDSERRKELMEDELDDDNMEDEEEFEDEEDEADESGNELDLSEGEEPVESEDDEDMVDEMMSDEEDNVDDEKIVEISDSEIETSAPKKSEETEDIYGRKINKSTGELIKFDPAAARKKLEELDATSSTGEQKQRVERAVNSIINKLSDAMLIKSQQGIAELWANSSKNDVKSALYKFLSLQDSLLTTYGALIAMCHTISNEISAHFVECFMCDLVKSMQEEEEKSMENCVIFTAFLVVFRILQPSILIEIIDKLAENLNLTNLFAIRTLIAYAYKSLKKTSWPLVTQKIDEIHSEFEKKSALPRAKFLLEEVILLKKSPPKAIDYDVV--ERQVKILHGITKKKGSSASSDSKELSMTLNDLLHAEQRGRWWIIGSAFRLP--------EQGGYGLLASASAAGQKKTGSFPPEMVSLATKAGMNSEVRRHIFCSVASADDEDDAFERLLKLQLKGEKERELVHVLIAMMMKEKTYNAFYATLLQRFCEFNKRFVITLQFALWDRLRECDQLKPFQRGSLAQLLQHLISNEVMSITVLKTVEWATRSARLTTILKKLFLGLAKSPESVLKRVFEPVIDQQKRTKFEL---------LSEGMRVFWHMNLNDFAAYQKIDKW.................................................................................................................................................................................................................................................................... 812
3 -23.100[A] KOG1104 Nuclear cap-binding complex, subunit NCBP1/CBP80  ali follow..  12  2........................................................................................................................................SRRRAHDTEDEGYDHRRNKRRR-QEIEDRLESLILRVGERSTSSVESNLEGLDLGTFRLKILRILSDCAVRMPEKCTVYTTLVGLLNAKNYKFGGEFVDHMVKTFKESLKMCRWDAARYSLRFLADLVNCHVISATSLLQLLDTMIDVSNEDTVFAVLSTLPWVGRDLYEKKESALESLLLRIEVYL-----NKRSKKHHNALRVWSSDAPHPQEEYLDCL------AQIRKLRQDNWAEKHIPRPYLVFDSILCEALQHNLPTIVPPPHHDNFEYPMPWVVYRMFDYTDCPDGPNLPGAHSIERFL-----------IEEHLHHIIETHHERKDCAAQLLSFPYKHKIPLEIVEVVFA-MPTPRYLDICYGSILIELCKLQATLPQVLAQATEILFMRIDSMNTSCFDRFVNWFSYHLSNFKFTWSWDEWDSCLLLDGEHPRPKFIQEVLQKCLRLSYHQRITEMMPTT.............................................................................................................................................................................................................................................................................................................. 475
4 -18.200[A] KOG2217 U4/U6.U5 snRNP associated protein  ali follow..  13  3...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SSSSGKKHKKDKKNRHRSRSSERPRRVTEDEDVTLDLTDDSSSRHRHHKHKKHKEHRHKHHKQKERERANEVISLEESDSDSSDCVEVPVQAQVQAQAKLRDARESSNRDKERDSGRDRELLRERERERDRERERDRDREKEREREREKERLREREEREREREKERIREREKERLRERERERERERVRELTAPPPPQISKHAEYESRREREIERERDARKRSGRERERERNRERSRSQSPASSSRKPATKEREPSSR 259
5 -16.400[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  11  444...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TEVEFEEVMSRNRTVSSSAIARAVSDAAAGEYSSAIETLVTAISLIKQSKVAHDERCKILISSLQDTLHGIEAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDTDAHWIIKQQTTSIPAPPSSQQN 696
6 -15.500[O] KOG0314 Predicted E3 ubiquitin ligase  ali follow..  10  507..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GREEFEAKKTEMKRKRENEIRRSEGGNVVRDSEKSRIMNNSAVTSSPVKPKSRQGPPPPISSDYDRRRRSDRSSPERQSSRRFTSPPRSSSRKSERDRHHDLDSEHDRRRDRPRETDRKHRKRSEKSSSDPTVEIDDNNKSNVTRISFPEESSGKQRKTSKSSPAPPESSVAPVSSGRRHHSRREREMVEYDSSDDEDRHFKRKPSRYKRSPSVAPSDAGDEHFRHSKRSKGERARA. 744
7 -15.200[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  11  233...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMSD. 484
8 -14.400[P] KOG4505 Na+/H+ antiporter  ali follow..  6  4..........................................................................................................................................................................SQVEISKPHLAYAIIGGFTSLFM--LCSLIIKEKLFLGEATMATATGLIF--DYITEELARVLLVVEV--FAAGAELPRAYMLRHWRSMFVMLLPVMIFGWLVSTGFMYALIP-----RLSFLESLA--IAACITATDPVLASSI---VGKGKFARRVPGHLRNMLLLAIYLIIEKPARHAGRDWVCIIILYEKFSERRGLMDRESFLVFYFVLALFCGGIGTIIGVDDLLVSFCAGAAFSWDSWFSKKTEESH-----------------------SNVIDLLLNLSFFVYVGAIMPWPQFHMPHMDLSVWRLVVLAICILIAR---REALFAGHFGPIG----------ALYTCLVARAELEVHSTVPEPNDAIENPEIPNWYCIQVM----WPVVCFLVLSSIIVHGSSIAFFMLGKRINTLALSFTRTRDSHFAFNLPRVRQGQSLPIKRVDALRSSANSIASSIRRRHPVNIQEDEDADISTVSLPEAAHLREERAESPRGGHYDAEEFPSEDYESRQPRRSNEEDREEEMNPGDETYLIGEDLVVEDSQGNIISHTSSRDANGPSIDEKLAQGDPKAKSFGRKFRSFLRRSYDTFQRNLHEPDDERQREPTLGHIESSIENHRPRYSRQNSESHLRENSVERRRREQVLTNIGDSESEDDNIPRPGIVPFYNENNESSSDTRNGLLSDNVSESRSRRPSRAPSAAVSSEGSPVEEDNEAQHRPNIRFLELTR 756
9 -13.900[A] KOG2548 SWAP mRNA splicing regulator  ali follow..  9  689..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SSSSTGNQTGKYSSATETGSGHPSSGGGGRPNLRERLKRKMQNLLNRQYKADKRAEIEKTERERLQQQEREDEMRELALKLRRRRRELRHKYGTPSSGKLSDSDAESVASESQLAKSSTRRSRSRSESRRRSPPPETQHSRRSSSRTERRRRTRTPSPKYNRRQRSRSRSGSRVERKRRSHSRRRSGSRDRRRSRSRRSQSRRRRQRDRSIERNREREQYRQQHQQQNERLRGRDRDREADYGHGGSGSSNRGR 942
10 -13.500[S] KOG4610 Uncharacterized conserved protein  ali follow..  10  299.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KNSLVIILQLYRLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS.... 523
11 -13.000[DZ] KOG2229 Protein required for actin cytoskeleton organization and cell cycle progression  ali follow..  8  91.......................................................................................................................................................................................................................VGFVSQVCSCFPRETANFPSELKQLLLEHHKSLPFELKEKILSCLTMLRNKDVITAE---ELIQSLFPLLVAYSSHGNSLGVNSHAKELRKIIYTNLISLLKSCNTNGKNQKLNKSTQAVCFNL--LDQPDSQGIWATKLTRELWRRG-------------DDSRTVEIMTQAALHQDVK---------FLDADREREENFEENSEDEDGFDLDALRHKMQVNKKTGRRGKKLENAIKTVKKK-FSAIHLLRDPQGFAEKLFKEHLSGKTKNKLMQLLSRLIGTHKLI-GIYTFFLKYLTPKQRDVTRIMSACAQACHDLV---PPEVINVMVRKIADEFVSDAAGINTIREICSRAPLAIDEILLQDLVEYKGSKAK-------------------------GVNMAAKSLIALYRDVAPEMLKKKDRGKNAAMEVQEAKKGGKDSKRPQFGADNSVQGIAGIELLAKWKKEHGEESENEDADANWEVDVDSEEDDVDGEWVTMDSDKEYDVDMEDSDDEKDNAKGKESDSDLELSDDDDEKEVKDEQEDADIDPEAAFREIASTRILTPADFAKLQELRNEESVAKIMGIHKQDKREELVDASTLTGPIKYKQSREERLQKVLEGREGRDKFGSRRGKRDNMRSTTNREKERRKNFVMSIHKRSVRGKQKMSLRDKQKVLRAHITKQKKKG 766
12 -13.000[K] KOG3794 CBF1-interacting corepressor CIR and related proteins  ali follow..  10  328...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEE 592
13 -13.000[R] KOG3263 Nucleic acid binding protein  ali follow..  6  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SSSRSGEHRRNYAQGRNYESSRSRGDQRDRDYREYRRNYRDERSSRRYEDSQRRDYSPARRRDRYERHRESVREESPRRPVEHERNWQPELKHGRERFRERDYEGRRDRKERRDGVSPFSPEGEGLERKREHEKLQAPSPKEEEERPVDQGDKMDGVKEDKDGSLEVGKSHDAMTRTKSAEEEIVEQEDEATAEMKRIMGFSGFDTTTGKKHGDVGQVYKQKKTKYRQYMNRPGGFNR 239
14 -12.900[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  7  196...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDREREKKKKRSKSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEKYRPPPAHHNMFSVPPPPILGRGNASTNPNPDNGQQSSGDPSWWRQ 448
15 -12.600[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  10  7...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NADDDGKRVQNEEGNYDPTDHQRQMEDYYKQYEEQRQVANSFHNTTGRPDLVAMQARLAETEQAIHRLNEEKKQPPPGFPIMTTPATQPEISIPRSGENKSSRSPSWAREARRSRSRSRDRRGGRSRSRSPSRRRTSRDRRDDRSSRRRRDRSHSRSRSPPSSANGSSHWSSSNRHSRRRRSRSYSRERDRNSRRDDRRSNLSNNDRYSDWNPGVPS 223
16 -12.600[A] KOG2253 U1 snRNP complex, subunit SNU71 and related PWI-motif proteins  ali follow..  7  17.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FEKPYKLLCRASHWGIAPFFYSHSFVPSIRFISIILKLLPLLMNTNEIAIDAAAVAQGAEKELHDDREAKNRPEASKRSRRSRSSSNSSSESDSSSSRSSSYSSRSRSRTPQRSRTSKRRRSNSHASEDSDDAREKRAFKQMMLDKKQAYLARLKRWESRERQMSKRYEREERKEKDRKKTLQKEGKRLKLFLEDYDDEKDDPKYYTSSQFFQRKRDYEREREADQKDRMQEQQEIEELKRQIMEEAANDE 267
17 -12.500[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  11  726..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EEPVDLASTIPIPQPELKAFVKKEKIDLILPTSRWAREDDETDDEQKKSYSSGSDNAGGITFKTDEEDLKADPSVRVQPENEIDVEQRQKLRHIEIALIEYRESLEEQGMKNSEEIERKVAIHRKRLEADGLSGNQRVLPEKREKREDSRDSSRKRNRSESQNRSQSPPQKSLTRERVRDHDLDKDRHRDRDRQQHDLDKDRKRRAKSSSRERDDHDRSRERDRDWRRRGMR...... 957
18 -12.400[S] KOG4843 Uncharacterized conserved protein  ali follow..  7  285................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KEQKDYHRGKRVAEGSTANVDPWVVSRGNPQGPTEVGPKDLSAPVEGSHLEGRETVGENKVDAKNEDRFKEKDKKRKELKHREWGDRDKDRNDRRVSVLVGSVMSEPKEIGREERESDRWERERMEQKDRERNKEKDKDHIKREPRTGAEKEISQNEKELGEASAKPSEQEYVAPEQKKQNEPDNCEKDERETKEKRRERDGDSEAERAEKRSRISEKESEDGCLEGEGATEREKDAFNYGVQQRKRALRPRGSPQTTNRDNVRSRSQ 552
19 -11.900[R] KOG2295 C2H2 Zn-finger protein  ali follow..  6  262................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHR 513
20 -11.700[Z] KOG3809 Microtubule-binding protein MIP-T3  ali follow..  12  117...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKG-KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDS 368
21 -11.400[J] KOG3942 MIF4G domain-containing protein  ali follow..  11  117MTTSSGAPAEALGNRSSLILPLTNGPGVGVAPGLGPYGNVNRRQAGHSLGNMPGLKANHRSILVTYPINTGALSGQLPLMNSPSSGNILHTTNRVKFAPEPRGHKVASHNQFGQLNNNYAQPYQANINGVDPYMNGNALQRSKSLSSADALTRGMAGLGLGLGNE-VADIGQFTPEIQALIDTALEDPNKLNSRCLLTSQFIKRAVESRRFALPISRLCLNI--IAREQKETFLEALLNTCRQWYQEREKVRFTAFMAFLTEMFC-PLVLLSLLSKCCGDCVRP-SLSEIECLFYVLTCIGQDMEQQLPQQLELLMSLVRDALNAGESAASIRRTLLQLIELKASHWQ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 496
22 -10.900[T] KOG1882 Transcriptional regulator SNIP1, contains FHA domain  ali follow..  7  2................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAK 221
23 -10.700[R] KOG4520 Predicted coiled-coil protein  ali follow..  10  52.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AKGRAPCAGPSREEELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGSEA............... 263
24 -10.600[R] KOG4264 Nucleo-cytoplasmic protein MLN51  ali follow..  9  1..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNEHDLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQE--RSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLG 288
25 -10.600[R] KOG2888 Putative RNA binding protein  ali follow..  12  203................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QKQIEKRIEQYCREQGVTVHQLSTGRSTAGTGGGPGAAGQDADYQDYPEGGVERGSGGRGGGQAGSRSNAYPQPNNYRNDYDERDYYAAASGSSYGRGRGGYEDYPPAPLPPQMPYGERERERDRDRDKNKDYDRHRSKHKKKHNHRQSSRSRSRSRSRSRHRSERHERKRDGGGYERSSKSRHNEHYEERERRHR........ 398
26 -10.500[S] KOG2889 Predicted PRP38-like splicing factor  ali follow..  11  125....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NDFRKLRYMNKMGRFEAIYMDDFIDNLLREDRYCDIQLPRLQKRWALEEVDMLPSYKSLLDGDLVAMSDSDSEEEEVTKKEKPRLTSRRRSRSRDRERDVGDRREVREREKLKERRERGDDEPGPSSSGSGRRDDRDDRRRDRDRSRDRDRRDRRDDDRRDKKKESRRGGADNDEEREIAEANALRAKLGLAPLER.... 320
27 -10.500[P] KOG1966 Sodium/hydrogen exchanger protein  ali follow..  9  2................................................................................................................................................EVRDYGLAELFHWNWDHIHKVYVITT-------LVASLAKILFNLMKPLSKWLPDSSLLIIVGLGLGYFLNQTTLSGVHLDSHAFFLYLLPPII--FDAGYFMPNRALFKNFDSVLVFSV-LGTLWNTFAIGGSLLIMSKYQLFTMPFTTFEILVFSALISAVDPVAVIAIFEEI-------HVNEFLFINVEALFN-------------DGVTVVLYQMFKSFALIGSENLSPWDYATGGLSFFVVA--------LGGAAIG-------AIATSLATKYTQGIKILAPVFIFLLPYMAYLTAEMVSLSSIIAIAVCGMLMTEAATNSVKYFTKM-LAQCSETVIFMFLLSTLTSEHHVDFIFIGATLVFCLIYRAIGI---IVQCFILNKFRAKKFEVVDQFILSYGGL--RGAIAYGLVVSIPASIQATTTICVIYFTVFLQGITIRPLVNCLNVKKKEHREATMVESVYNKYLDYMMSGVEDIAGQRGHYSFIENFERFNAKVIKPVLMRHEKRQSFDATSIIRAYEKITLEDAIKLTKVKSTLQNKRLEKVKSEVRVAPEQTTVTPKDVQLARFMQSGENIDQLYTLFSDLLDKKLNELKVQADKVDKANDDDIQDDYMAEMGSHSNLGFMHHSADQLDSDSVFQRRGRRLSTGDLKGHCGTSRKPKHSMFELRH..................................................................................... 650
28 -10.500[T] KOG2370 Cactin  ali follow..  11  2...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GKDSKKHKKERRRERSPSTSDSDEERLQKRLAEQRSLKKDEKRRQKEEMKKNESAEEKRARRMEKKMRKDAKRKDADAEDTLIPPELNYTNLNNPFNDTKLTQT--GKKLEREGKSGLTQDEITKQTSQRIRKNLHEAAEFKRIRDSRAAAKEDMEMMKRDADLRAGQISDTKEREFQMDQIKERTRIRIDQGRAKA.... 199
29 -10.400[S] KOG3869 Uncharacterized conserved protein  ali follow..  10  199...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KNKKNKKSKKSKKKKKNRRSSNEESSDSESNDSDDDLDRKLARQVSKLKGDQGDLKLDKLLDAKYRTISNQLDMATKKKKSKKSKKKKSSDSSDESSDEEEEPRRKHKRSHSSEDRNQRERRRSRSPRDRKKRQSRSPEQRQRQRSPEERRERRRSRSRSPLARRQRRTRSPEDRKARRQSKDTSKQREKRRSRTPEERSRSKRSRSRSSKGDDKRRIAERPPPSRPTGKPKLSEADREARLREMMDNATWREADRSQVVRKHRE 463
30 -10.100[R] KOG2891 Surface glycoprotein  ali follow..  7  246..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KFVDKTQAINICVSFDKQKHLSDSNIQRRERIRKKFIAKAKAEDEEREKLKKQQEEELDRERQKQEELKKAEAEKQREREERRKEKHMKKIQERGQVEISQKIRIEERKLMIAQRKLESIRTLEKLFERIQLKQRDKNRRVKQDDDKDIQRGRLVEKYKAATEKLVCDQRKIVQEIKSNTPLLGLLKSKSKKSAVPVDASSEDEAAASKRHKMGNGVTESAPPGDVNSALNPLNAVAA 483
31 -10.100[S] KOG2812 Uncharacterized conserved protein  ali follow..  10  5.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLAHQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRK 259
32 -10.000[K] COG5164 Transcription elongation factor  ali follow..  8  2.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SDNSDTNVSMQDHDQQFADPVVVPQSTDTKDENTSDKDTVDSGNVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDDDEDDDDEAPTKRRRQERNRFLDIEAEVSDDEDEDEDEEDSELVREGFITHGDDEDDEASAPGARRDDRLHRQLDQDLNKTSEEDAQRLAKELRERYGRSSSKQY 264
33 -9.960[S] KOG4051 Uncharacterized conserved protein  ali follow..  7  173...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KNDNNKQEKNATIKVKELPEYHTEENDSPIDVQKEPIKEVQSDEKELQREHMSEEEQKMKSTNKTAAPVRKSQRLKRSKEVKFEDEEKEEIEEDNTKDEEQKEKKEEIQEPKITHNEEVDKEKNENEEGDDEREKSTSYENTNGSESEGVDEGVDEELGYESEREAEGKGKQIESEGGNLKKKTENKKGDDQQDDTKKDSKDKNEPLAKRTRHSSSTGNTSNETSPKRKRRKAGSRKNSPPATRVSSRLRNKK 425
34 -9.900[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  10  455..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................STAEEATKCINHLHKTELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKCDRKDDAKKGDDGSGEKSKDQDDQKPGPSERSRATKSGSRGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSASREKRSVVSFDKVKEPRKSRDSESHSRVRERSEREQRMQAQWEREERERLEIARERLAFQRQRLERERMERERLERERMHVEHERRREQERIHREREELRRQQELRYEQERRPAVRRPYDLDRRDDAYWPEAKRAGLDERYHSDFNRQE 744
35 -9.840[S] KOG2365 Uncharacterized membrane protein  ali follow..  6  242......................................................QTLDDSGSYLHRLQKLFDKNDFERSLSNFSICGRPGNEPLSPGLQSDVEDVSLSDTVDSTDTFDVKPETEVPSHQSDTFF-PVILHLIYTVGEYTGITKFVCNKISEVYAALRFWAIEHHSAVLPLCLPGVLELNYKINTI-VRDSLKASVESVTSILMIILMLLIIV------LSVFFCVNI------------YSETIEVAYLGKDLINKTITDRPELIDILPANMQSSIEDALDNAHHYGRR-----------KIETYIDDWLADADKVHATKLKEQILEVWDRLIQYWIDFNKAGSSYGPRVPTDALKSTFGEIVDNPDSYCVHLLTDGRLFNQGHFKELVLVAKQGIIGWAQSNTQTILEVAESLWHIIRTNMSMIMGVTGEILSL--QACIEFILDMIVFFTLSSSQEKYAPLQITKYLKIADALENSITVVLV-SMFRCSTFTGLFTWLVHTVFGARIVFLPSALAAMLAAAPFLGSYQDRFYAGLILFLLQFFVPSSFETAIYADLKGGHPYLNGLAIAGGMYWI................................................................................................................................................................................................................................................................................................................................. 795
36 -9.720[DK] COG5103 Cell division control protein, negative regulator of transcription  ali follow..  11  845...........................................................................................................................................TFVSIHVPPLNVPNAEGEIEESVCDNILFAINNLSQLNFNEKLKDVKDNLTPAYLPWFSHYIVTQRVSRENFLSLYGKFLEELKS--SDLYKIVFRDTLQAILDIMNNSEKTNLKNLGSWLGSI-NKPITTLQV--SFKDLLLEGIDSGRIDRVLKVLEKASVIFKPPNP--LMGILKLLVELYQFADFRLNLKFEIELLLNNLNVKMDNIEPSEMYRNHLVQKADLEKELPEDVLNAEFPD---------------------GTDVITQYIVAASSQITVTDAVAQVFGKPKPAIKNITQLIIQQSVLEIISAVVRRSVGIAAITTK---SLLQKDFAAESNPSRLLLAARQMAK--------------LAGNLAMVT---REPLQMLMINNFRTIALQDVENVHAAVAQAIDELVSQNLFVSVIESVASETAIAEIDAEI....................................................................................................................................................................................................................................................................................................................................... 1261
37 -9.560[S] KOG3683 Uncharacterized conserved protein  ali follow..  9  232................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TSNKQKPVMGPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQYRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSERPSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSFAEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTDYQN 483
38 -9.280[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  11  144..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SPVTDFREATCRQYEENNCNRGGYCNFMHVKLVSRELRRKLFGRYRRSYRRGSRSRSRSRSISPRNKRDNDRRDPSHREFSHRDRDREFYRHGSGKRSSERSERQERDGSRGRRQASPKRGGSPGGGREGSEERRARIEQWNREREEKEEGGA..... 296
39 -9.000[K] KOG2478 Putative RNA polymerase II regulator  ali follow..  10  327...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD............ 531
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;