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Query: [JU] KOG2153 Protein involved in the nuclear export of pre-ribosomes, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSFLFTNRVAIKILTSFFKIILRGVKINDYFAENMGFASASREEKLKMLKTNKTRKTTKHLNRLAKRKKLSREIRDGMADIKSRKSADLRQRAVNIEDDFIADRQAHYENSDEDLPLDMMDADIDWENSAFANAKRRLEKKRSGVESDSDDEDDVEKKKRKFAGLLEEGHEELLPIKLKDGTLIRPTREKEVKEDEEEKSGDEEEEGEEDEPHREDFSHLSASELIAKRRELMQEFKDTIASHANMLLSNPQVNIVRLRDLYNLCNGEKIHSLVRESVQKLAIASTLQVLLDILPGYAIREQTAEEKAQKQKKETRNLVNYEESLLRYHLKYLQLCEKLSNKLVGKDRHNDESTFTFKMGILSVKALARIVVSAPHFNYSTNIVSSLVRLSLAKNETVIREVCEAIRTVFKEDIHLKITLFTARSISTLVTKRKGRVPPELLRTLLSMNITEVKDEDKKSGKDALIAKKYQIKKEKASKTAKKYKKQLARLEADLLEVEAEESMSKKLKNATEAMKFAFQSYFSILKRMPNSALLEPVLEGLSKFAHLLSIEFYEDIVSTMENMVQNENLKSLDQLHCINTVFVILSGDGQLLNIDPSKFYRLAYRVLNHLPFEKRPEQRKNQIIMAAKTLETMLVIRRKAVPLSRVAAFVKRLLSIATVLDDFPALCIVSLVRSLFIAHPKLSSMIEDEEGGAPGIYRPDIDDPDVANALASDVRDELSMLARRRNTELSRFANNILYGVPSTGIFKLNPQLSSLKPWILMGQLMDNAKDAYDKVESKYLDDLEKAAKKRNQSVTPKNINFHISNWLAASKLast
1 -184.000[JU] KOG2153 Protein involved in the nuclear export of pre-ribosomes  ali  100  1MSFLFTNRVAIKILTSFFKIILRGVKINDYFAENMGFASASREEKLKMLKTNKTRKTTKHLNRLAKRKKLSREIRDGMADIKSRKSADLRQRAVNIEDDFIADRQAHYENSDEDLPLDMMDADIDWENSAFANAKRRLEKKRSGVESDSDDEDDVEKKKRKFAGLLEEGHEELLPIKLKDGTLIRPTREKEVKEDEEEKSGDEEEEGEEDEPHREDFSHLSASELIAKRRELMQEFKDTIASHANMLLSNPQVNIVRLRDLYNLCNGEKIHSLVRESVQKLAIASTLQVLLDILPGYAIREQTAEEKAQKQKKETRNLVNYEESLLRYHLKYLQLCEKLSNKLVGKDRHNDESTFTFKMGILSVKALARIVVSAPHFNYSTNIVSSLVRLSLAKNETVIREVCEAIRTVFKEDIHLKITLFTARSISTLVTKRKGRVPPELLRTLLSMNITEVKDEDKKSGKDALIAKKYQIKKEKASKTAKKYKKQLARLEADLLEVEAEESMSKKLKNATEAMKFAFQSYFSILKRMPNSALLEPVLEGLSKFAHLLSIEFYEDIVSTMENMVQNENLKSLDQLHCINTVFVILSGDGQLLNIDPSKFYRLAYRVLNHLPFEKRPEQRKNQIIMAAKTLETMLVIRRKAVPLSRVAAFVKRLLSIATVLDDFPALCIVSLVRSLFIAHPKLSSMIEDEEGGAPGIYRPDIDDPDVANALASDVRDELSMLARRRNTELSRFANNILYGVPSTGIFKLNPQLSSLKPWILMGQLMDNAKDAYDKVESKYLDDLEKAAKKRNQSVTPKNINFHISNWLAASK 812
2 -117.000[JU] COG5117 Protein involved in the nuclear export of pre-ribosomes  ali follow..  20  5.....................................................................................................NRSQFRIQERTAKKRKHEDSLLEGNVFQNAPEDMDENTIYSAKGSSWDEEEQDYEMVPRKNRSD-TSNLVEGLPIKVNGKVERKLHKAQE-KPKDDDEEDEDSNDSSEDDEGPNEEQEAEAKEDEPDTEEKILQLKEDIADLVTKVMEEPEENTAALGRLCKMVESKNP------NTCKFSMLALVPVFKSIIPGYRIRPLTETEKKEKVSKEVSKLRNFEQALVYNYKNYVGRLQSLSKTPSNAAPIQV------SLGILATQAAKELISTASHFNFRTDIFTLLLRRICKPRDPTSIQIIQTFETLLNEDEEGSISFEILRIFNKILKTRNFNIEESVLNMLLSLDVLHDYDPNTKLKGNVSAPKLKKKDRVHLSKKQRKARKEMQQIEEEMRNAEQAVSAEERERNQSEILKIVFTIYLNILKNN-AKTLIGSVLEGLTKFGNMANFDLLGDFLEVMKELINLSSAEVRKALLCIVSAFSLISNQYMKVNVDLSKFVDGLYALLPYICLDADIELSVSTKAELLLKALDHVFFRSKSGTKERATAFTKRLYMCISHTPEKTSIAILKFIDKLMNRYPEISGLYSSEDRIGNGHFIMEADNPSRSNPEAATLW-DNALLEKHYCPVVTKGLRSLSSRSKECSK.................................................................. 663
3 -75.500[J] KOG2154 Predicted nucleolar protein involved in ribosome biogenesis  ali follow..  11  1........................................................................................................................................................................................................................................MVLLISEIKDIAKRLTAAGDKQYNSIIKLINELVIPENEEDETEKNLRFLVMSLFQIFRKLFSRGDLTLPSSK-------KSTLEKEQFVNWCRKVYEAFKTKLLAIISDIPFETS----------LGLDSLDVYLQLAELESTHFASEKGAPFFPNKT------FRKLIIALWSSNMGEIEDVKSSGASENLIIVEFTEKYYTKFADIQYYFQSEFNQLLEDPAYQDLLLKN-----------VGKWLALVNHDKHCSSVDADLEIFVPNPPQAIENESKFKSNFEKNWLSLLNGQLSLQQYKSILLILHKIPHFHTPTKLMDFLTDSYNLQSSNKNAGVVPILALNGLFELMKRF----NLEYPNFYMKLYQIINPDLMHVKYRARF--------FRLMDVFLSSTHLSAHLVASFIKKLARLTLESPPSAIVTVIPFIYNLIRKHPNCMIMLHNPAFIYVDPFDVHESDPELTHALDSSLW-ELASLMEHYHPNVATLAKIFAQPFKKLSYN--MEDFLDWNYDSLLNAESSRKLKTLPTLEFEAFTNVFDNEDGDSEASSQGNVYLPGVAW..... 552
4 -68.000[J] COG5593 Nucleic-acid-binding protein possibly involved in ribosomal biogenesis  ali follow..  13  2...................................................................................................................................ATLYPKPKRGQKIIFNEEGEGTIDTKPQGVMFDPGVPWYNIPLPELHED------KKFVNVDHVSELETRGLLLLKEDSERFSETLGHGTADKRMLQTLISSGTTSDRISALTLLVQESPIHAVKALETLLSICSKKSRNEAT------QAITTLKDLFGGLLPDRKLKYMKQQLGSKNVTDKHLMVWAFESFLKSFYFKYIQIIEALSFDALLF------------VKSQMVSTIYDLLKAKPEQE--QNLLKLLINKLGDKENKIASKASYSILQLEAS--HPAMKLVITKEIERFIFAPSTSRTSCYYTLITLNQTVLTHKQVDVANLLIEIYFVFF----------TKLLFALEKEEVADAPTLEKKSLQSDSKNKKSQKRKKDEDLRKEAEENVNSRVISAVLTGVNRAYPFAEV----NSEKFDKHMNTLFAITHTASFNTSVQVLMLIFQASASRDFISDRYYKSLYESLLDPRLTTSSKQS--------LYLNLLYKSLIIDNNIPRVRAFIKRMVQVSAWQQPPLVTGLFHVMHQLVIATTALRSMFTNAEKKEHLSYDGRKRDPQYSNADGSCLW-EIHPFLNHFHPTVSLLAKSLVYGEKILGKPNLSLTLNHFLDKFAYRNPKKSAAARGHSIMQPLAGGLS---KGYVPGSTYSGVPMNSEQFTSKKQ 684
5 -49.100[JK] KOG2038 CAATT-binding transcription factor/60S ribosomal subunit biogenesis protein  ali follow..  11  43...........EEVLRL----KQDYLMLATLDENEEVIDGGKKGAIDDLQQGELEAFIQNLN-LAKYTKASLIEEDEPAEKENSSKKEVKIPKINNKNTAESQRTSVNKVKNKNRPEPHSDENGSTTPKVKKDKQNIFEFFERQTLLLRPGGKWYDLEYSNEYSLKPQPQDVVSKYKTLAQKLYQ---------------------HEINLFKSKTNSQKGASSTWMKAIVSSGTLGDRMAAMILLIQDDAVHTLQFVETLVNLVKKKGSKQQCLMALDTFKELLITDL---LPDNRKLRIFSQRSGNKDSRDRRLILWYFEHQLKHLVAEFVQVLETLSHDTLVTTKTR------------ALTVAHELLCNKPE--EEKALLVQVVNKLGDPQNRIATKASHLLETLLCK--HPNMKGVVSGEVERLLFRSNISSKAQYYAICFLNQMALSHEESELANKLITVYFCF--------------------------------------------------FRTCVKKKDVESKMLSALLTGVNRAYPYSQTG------KVREQIDTLFKVLHIVNFNTSVQALMLLFQVMNSQQTISDRYYTALYRKMLDPGLMTCSKQA--------MFLNLVYKSLKADIVLRRVKAFVKGLLQVTCQQMPPFICGALYLVSEILKAKPGLRSQLDDHPESDDNKYDPFSRNPLFCGAENTSLW-ELKKLSVHFHPSVALFAKTILQGNYIQYSGDPLQDFTRFLDRFVYRNPKPHKGKENTDSVVM-------QPKRKHFIKDIRHLPVNSKEFLAKEE 804
6 -13.000[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  11  478.........AIETLVTAISLIKQSKVAHDERCKILISSLQDTLHGIEAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSN----------------FTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDTDAHWIIKQQTTSIPAPP---------SSQQNNIIVL.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 702
7 -12.200[R] KOG2295 C2H2 Zn-finger protein  ali follow..  8  313.....................PVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQR-----------LRDCEMGAIVNRDLSRRV-RPANGITAHKQVVRSDIKLCAKIALNLDEK...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 628
8 -12.000[A] COG5181 U2 snRNP spliceosome subunit  ali follow..  10  1..........................MSTVEDVEIERLRAERELLRRQKEAAKNSSTNGSVNIEGTQDSNDLQYNAHLFKSSNPKEEYDSAIDVRNDISQDEDDYKRTNDVNDSYRLVRQYEAPKELLNEYADESYDPMQERQSKKQIQDRESDYQKQRYDRQEKEERRVHMELNQRRREGTLKEVEEEESISDKKRELELNNTEISQKPKRSRWDQAPPSVTQVSTTKRRSRWDKAPENFTISEHVIENGISE-DLINKEVNVVEEKLRPPVRLLTEEELNELELPAALPTEIPGVGDLAFFKQEDVKYFGKLLKVEDEAKLTIAELRERKILRLLLKVKNGTPPMRKSALRQLTDQARDFGAAALFNQILPL---PFTHKILVVIEPLLIDEDYYARAEGREIISNLAKDHVDEYVRNTTARAFSVVASALGVPALLPFLKAVCRSKKSWQARHTGVRIIQQIALLLGCSILPHLKNLVDCIGHGLEDEQQKVRIMTALSLSALAEAATPYGIEAFDSVLKPLWSQRHRGKSLAAFLKATGFIIPLMEPEFTRRIMKILLREFNSPDEEMKK------IVLKVVSQCASTDGVTPEYLRTDVLPEFFHCFWSRRMASDRRSYKQVVETTVVL-------AQQVGSRQIVERVVNNFKDESEPYRKMTAETVDKVIGSLGVSEIDERLEELLLDGVLFAFQEQSVEEKVILTCFSTVVNALGTRCKPYLPQIVSTILY......................................................................... 822
9 -11.700[S] COG5369 Uncharacterized conserved protein  ali follow..  10  289...............................................................................................................................................................................................................................................ITQLFCLVRQDPCIRLLSISCLVTLYKAGILSKNQTKEIQMIVTPILIRLFFE-----------SREAKQIAPRILAIIINENEIMQKT-AGFIDAAKYLLEYATKEEENEINFLSDELQSSAACECLLSLSRSVYILRADADVSEPLIKLLSDPDTRVKSTATSAICNLVLKFSPLREKFLFIDTLISNISTKDSSLRKKTVWVLRHVVF------------------------------------------------------GDDETIQLEPLKKIGASKLVELCNDEDLGVQEQMLQVLRNFT-LLKMVPMELLAKILLEKLESKNPILIEPSIYILVHIAASDGELRDSILRQTKLLLLVKEIM---------LQEAQRLKPEQMSTNVSSPESDSEMDLQEMRPPFDIYEEDTYEPNSEILLAGIWLCINILWPKQCTSPSQEDKERASI---------------QNLGFGECLQMLQNHSSPDVRERVKDALMYI....................................................................... 725
10 -11.700[R] KOG1293 Proteins containing armadillo/beta-catenin-like repeat  ali follow..  10  289...............................................................................................................................................................................................................................................ITQLFCLVRQDPCIRLLSISCLVTLYKAGILSKNQTKEIQMIVTPILIRLFFE-----------SREAKQIAPRILAIIINENEIMQKT-AGFIDAAKYLLEYATKEEENEINFLSDELQSSAACECLLSLSRSVYILRADADVSEPLIKLLSDPDTRVKSTATSAICNLVLKFSPLREKFLFIDTLISNISTKDSSLRKKTVWVLRHVVF------------------------------------------------------GDDETIQLEPLKKIGASKLVELCNDEDLGVQEQMLQVLRNFT-LLKMVPMELLAKILLEKLESKNPILIEPSIYILVHIAASDGELRDSILRQTKLLLLVKEIM---------LQEAQRLKPEQMSTNVSSPESDSEMDLQEMRPPFDIYEEDTYEPNSEILLAGIWLCINILWPKQCTSPSQEDKERASI---------------QNLGFGECLQMLQNHSSPDVRERVKDALMYI....................................................................... 725
11 -11.100[S] COG5604 Uncharacterized conserved protein  ali follow..  10  3.................................................KLSSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETDAMAKEIDENERLKSSSGKIVQKLLETNHSLTTLQKVVQAFKAAAFLNEEEAEDLKYTI--------SDSKVFNDLLLLAIQYVPKVLNYH-----VPIQEDAKGKKFINTDSKVLPKLRPVLKSYGFSILRLLEGMTDAK---------------NISLLLREAQNVLPYMITYKFLKQFTQATVEVWSSTRDDSVRFSAVVLLRTLCLTADITLLEFVLKEVYLGMARQSAYTTVHTLDKINFLKNSAVNLFLLDAESCYLIGFRY------------------RQLAITLRNTIHQPSKDSRKPVQSWSYVHSLDFWARLLSQAAWLSREKGVASELQSLVY----PLVQIALGVIMSSPSSQLFP---RFHIIRSLIYLSRHTGV---------FIPLAPSLFEVLDSSYVSRKAKASTLKPLDFDVELRASSSYLRTKVYQGLIDQLLELLSEY-PELVIPAIVRSKRFAKRNRGLLTLVNRLEQQSKNQQKFAPIDSDSVEQFAQTIDWQQTPLGIYV...................................................................................... 651
12 -11.100[J] KOG2256 Predicted protein involved in nuclear export of pre-ribosomes  ali follow..  10  3.................................................KLSSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETDAMAKEIDENERLKSSSGKIVQKLLETNHSLTTLQKVVQAFKAAAFLNEEEAEDLKYTI--------SDSKVFNDLLLLAIQYVPKVLNYH-----VPIQEDAKGKKFINTDSKVLPKLRPVLKSYGFSILRLLEGMTDAK---------------NISLLLREAQNVLPYMITYKFLKQFTQATVEVWSSTRDDSVRFSAVVLLRTLCLTADITLLEFVLKEVYLGMARQSAYTTVHTLDKINFLKNSAVNLFLLDAESCYLIGFRY------------------RQLAITLRNTIHQPSKDSRKPVQSWSYVHSLDFWARLLSQAAWLSREKGVASELQSLVY----PLVQIALGVIMSSPSSQLFP---RFHIIRSLIYLSRHTGV---------FIPLAPSLFEVLDSSYVSRKAKASTLKPLDFDVELRASSSYLRTKVYQGLIDQLLELLSEY-PELVIPAIVRSKRFAKRNRGLLTLVNRLEQQSKNQQKFAPIDSDSVEQFAQTIDWQQTPLGIYV...................................................................................... 651
13 -10.800[U] COG5096 Vesicle coat complex, various subunits  ali follow..  9  5...................................................................................................................................................................................................................................TLVQQDFLEAPSVDALKTSLESNDYVKISAMKTILRVVINGDSLPSILMHVIRFVMPSRNKELKKLLYYYWEVCPKYNNDGTMKQEMILACNSFRNDLQH--NEFIRGA--------------------------TLRFLCKLKEP----ELLDPLIPTVRQCLEHRHAYVRKNAILAVFSIYQAESEGTCKRNALIVLFTIDPEKAKAWLLANFEQIPSLNASSLLVIIEFIRKVVLTKADGLEKLRFQSLLVSLTATNNSSVVFEAATSVINVFPD------AESLKLAASRLLALADREADNNAKLIMLDRISQLAARDKSILEDLITDVIPFLSS-------SDFDVCEKAISIIMGLVSSRNVE--DILNHFQKELTKSNGETEKDDGRRR--ALTKAIHSCAINFPHTAA-----TAIQYLLSHISDFQSKSASSVLSFIKEVMEKFPDLRSSN--------TKLLLSLKELRAGKIFRGVIW-EYCLTEDDIRVAWKSIRASLGE......................................................................... 477
14 -10.200[R] KOG4264 Nucleo-cytoplasmic protein MLN51  ali follow..  9  30.....................LRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPAYIP---RKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGR---------EHDKFREDEQAPKSRQELIALYGYDIRSA.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 247
15 -10.100[J] KOG1076 Translation initiation factor 3, subunit c (eIF-3c)  ali follow..  9  74.............TLSSFEDLTRAYQKALPVISKEENEVWEDREGRKNLSKNNSKSLGTLRQKVRKYIKDFEDDLSRFREAPDQESEAEDEVVALESDGGDAGDDSDAGVKPTEAVPKAVKSAPAKAAPADDDDSDDSIDWDSDSESETESSDDENQYQNMRERFLKRTTEKE---EKDDDKRKDKRKEQKTKIRKRAEDDEDGEWETVVKGHVVEKPKMFEKDAEIDVPLVLAKLLEIMSARGKK--TDRRLQIDLLFELRDISDQHNLGTAVSVKIHFNIILEVMQSMMKLLADIIMSESVAEEHEERLDDEFVKLLKECDPHSNDYVSRLKDEVNVVKTIELVLQYFERSGTNNERCRIYLRKIEHLYYKFDP-DVMDKLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQGNVKDAHHCLVDLMVTGKPKELLAQGLLPQRQHER-SAEQEKIEKQRQMPFHMHINLELLECVY--------------LVSAMLLEIPYIARMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRFIVNKKMNTKVESDRVREMLTKFIKEESL----RTYLFTYSNVYTSISIPSLAQMYELPVPKVHSIISKMIELMASLDDPSETVGM--LQALMQFVDKVTNLVDVNEK........................................................................................................................ 838
16 -9.810[U] COG5240 Vesicle coat complex COPI, gamma subunit  ali follow..  9  2..........................................................................................................................................................................................................................SYSKKDDDGDESIFANVNQVTVTQDARAFNSSPRKSRRLLSKIAYLIY------------EHFQEKQATELFFGI-----TKLFQHKDPSLR-----QFVYIIIKELSVVAEDVIMITSSIMKDTATGRET--------IYRPNAIRSLIRVIDA----NTVPAIERILTTGIVDPISAVASAALVSAYHLYPVA--KDIVSRWNNEVQDAVTSHNVGRKVASSPFFTSTLGYTPNASGISQYHALGLYRIRRHDSIAMNKLLQLLVSNLGTVSNSHAFVMLIRYISSLMDQNTQFRDQMVPFLHGWLKSKGDMVNLEVAMVRLKNISDDDLQPVVSVLKIFLSS-------RSATRFSAIRTLNELAMTRPHLVHSCNLNIESLI---------------TDVNRSIATYAITTLLKTGNDE----SVDRLMKQIVTFMSDISDNFKIIVVDAIRSLCLKFPRLTFLSNILCDEGGYEFKRAAEDCEYPKIAVRILS-----ILGEEGPKASEPTRFI........................................................................... 493
17 -9.800[YU] KOG2023 Nuclear transport receptor Karyopherin-beta2/Transportin (importin beta superfamily)  ali follow..  8  5..............................................................................................................................................................................PDQHELEQVIQLLQHAHSTDRDVQRNVQVQLVQLNEHQK---LSDMKEMIDATSRSLAGLLLKNNIRAKWNKYPQDVKFFVR--TTCLKSIGDQEPRATVGIIVTTIVMEENMCDWPDLLD---LATVLMQPDELMQEGALGALQKVDRYESEFLRPIMPKLLVFYEHH------------AAKMRALAMNCVNCILMVNND-FAIDQFLTSLFARHNDNDEEVQKQLCRSLTLLLDTEKMMPHLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDICRTMVLPHLDKLIPVLLGSMRYSETDPALKANDEDSSVPDREEDIKPRFHKSKQHGLGGLVESDDEEDED--DGGGDWNIRRCSAASLDVLASIFGKDLLDKLFPLLKDTLMNDNWLVKE------SGILALGAIAEGCMDGVVPHLGELIPFMLAMMFDKKPLVRSITCWTLSRYSSHI--ASDENFRQQFFKDVLANLLRCSLDGNKKVQEAACSAFATLEEE-PFLGEILD............................................................................................................................ 516
18 -9.770[K] COG5164 Transcription elongation factor  ali follow..  11  1MS---TN-------VSM-----QDHDVPQSTDTKDENTSDKDTVDSGNVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDDDEDDDDEAPT---KRRRQERNRFLDIEAEVSDDEDEDEDEEDSELVREGFITHGDDEDDEASAPGARRDDRLHRQLDQDLNKTSEEDAQRLAKELRE--RYGRSSSKQYRAAAQDGYVPQRFLLPSVDT-IWGVRCRPGKEKELIRKLLKKKFNLDRAMGKILSIFTGRI-YIEAPKQSVIEKFCNGVPDIYISQKLLIPVQELPLLLKPNKS--YKGDL--AMVDQISENNLEVMLKIVPRL...................................................................................................................................................................................................................................................................................................................................................................................................................... 420
19 -9.680[R] KOG2030 Predicted RNA-binding protein  ali follow..  11  613.SFMI-NFLPSCHLTMGLSLLLEDSFIERHLGERKVRSLEDDQIDPNVKENEVEHDLLSDNEDADSNINLSEPSSNTEITAFPNTEVKIEHDTGRIIVRSDSVNPEIEETKESEVVLDKILKKTDDEETTIILAGPSRKKQVSAKKTKEDKARAKQEAAKQEVPPVSSEPKNPSQVKRGQKGKLKKMKQKYKDQDDEEREIRMMILKSSGKEKPQASADKVVEKSESTKEYVKPEKSAAPKNPVELDDADEVPVGGDVDVLNSLTGQPHEGDELLFAIPVVAPYQALQNYK-----FKVKLTPGTGKRGKAAKLALNIFAKEKSCSAREKDLLKSIKE.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 949
20 -9.580[BD] COG5098 Chromosome condensation complex Condensin, subunit D2  ali follow..  9  207...................................................................................................................................................................................................................................EPVTKVSSLKMFIQRILAMCVKNHGQSSSIQSSLMTNLTYFLHLSVFNAELLKLLN-NYPQLTEDI-----LKEISTRVFNAKDTTGPKAISNFLIKLSEL-GIMLRQMNLVIT----------LNNSSITLRCSVVEACGNIVAELAQ-QQIAVLIELLEERFQDSNPYVRTKAIQGCSKICDQDRSSLVRRNSVKLLSKLLLKHGSQLRLSEWEEYLKGSESQLNSTLKKVESQETLNDTIERSLIEEEVEQDEGQCRTELEGSFNKSAELSRIENEVENINATNTSVLMKLKLMIVYYKDAISFIKEIHKSIELISNLLFSKNRNEVLESMDFLVLADAFDIELSEFGIKKMLHLVNDEGTSISVHLIECYKQLF-----------------------------LTAPDSCNMQEKAAHIAKNLINLSIGASIADLASLEQLLGMMYEQKLIDQHVIN............................................................................................................................ 666
21 -9.480[U] COG5215 Karyopherin (importin) beta  ali follow..  8  16......................................................................................................................................................................................................SPDQNIRLTSETQLKKLSNDNFLQFAGLSSQVLIDENTKLEGRILAALTLKNSPEAKNQIKTALTALVSIEPANAAAQLIAAIADIEL-GAWPELMK---MVDNTGAEQPENVKRASLLAESADPQSQALVSSSNNILIAIVQGAQSTETSKA-------VRLAALNALADSLIFIKN-GERNYLMQVVCEATQAEDIEVQAAAFGCLCKIM-SLYYTFMKPYMEQALYALTIATMKSPNDKVASMTVEFWSTICEEEIDIAYELAQFPQSPLQSYNFALSSIKDVVPNLLNLLTRQNEDPEDDDWNVSMSAGNHILEPVLEFVEQNITAD-NWRNREAAVMAFGSIMDGPDKVQRTYYVHILNLMNDQSLQVKETTAWCIGRIADSVAE-----SIDPQQHLPGVVQACLIGL--QDHPKVATNCSWTIINLVEQLAEATPSPIYNFYPALVDGLIGAANRIDNEFNASAFSALTTMVEY-TFVMDKLGQTMSVDENQ---TLEDAQSLQELQSNILTVLAAVIRKSPSSVEPVADMLMG......................................................................... 600
22 -9.180[OZ] COG5234 Beta-tubulin folding cofactor D  ali follow..  7  2...................................................................................................................................................................................................EEEESLEGIISIDESLITSRLSQILDDVLDDRSSSHSVEKLKDVAVKYLQFCQFQPDKLLSKVPNLASYLLKVKNIGKCNSITVILYQFCKIRGYKAVR----------------FPVGVQYIKELYTLLNESHFHYIVLLSQALNTPFPLNSLDDSLDVKKTIYTIAIKYLEN--------GIDKEASCLVLSRLFSR-DDGLDLLLGFLHHCESSKRSIFYKIGCLFSLSSFLKICPRNDCLQTVDVAFQFLNVAREDLVGQENSALRKLLCKCYTRLGIV----PVNSSPNWKYSISNPDSFFQLPDDSNEEVHIYLEVIVDFLLSSVS-DIDSFVRWSAAKGLAKIISRLPWNLAEQVIDAIIELMTENMFLNPIENTVNISITSLFFAKLAGAGLIKYSKCLHILPLIEVGLSYEVRYGTRVTGQSIRDASCYFVWSFYHCYSKSAIEGLQTNLLLQTVLFDNEINVAATAALFEVIGRHASISHINYVSVTDISNCYGDLCMKVAHFPQFRSCVFQRLFTNLQHWDVKVQQLSAFSLRQLSIKYPKELSIYLPPILDY..................................................... 573
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhang B, Jaroszewski L, Rychlewski L, Godzik A. Similarities and differences between nonhomologous proteins with similar folds: evaluation of threading strategies. Fold Des. 1997;2(5):307-17.