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Query: [L] KOG2299 Ribonuclease HI, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSLKCETERSKTWNNFGNGIPCVLGIDEAGRGPVLGPMVYAAAISPLDQNVELKNLGVDDSKALNEAKREEIFNKMNEDEDIQQIIAYALRCLSPELISCSMLKRQKYSLNEVSHEAAITLIRDALACNVNVVEIKVDTVGPKATYQAKLEKLFPGISICVTEKADSLFPIVSAASIAAKVTRDSRLRNWQFREKNIKVPDAGYGSGYPGDPNTKKFLQLSVEPVFGFCSLVRSSWKTASTIVEKRCVPGSWEDDEEEGKSQSKRMTSWMVPKNETEVVPKRNVYFKERHMSNILTFLast
1 -111.000[L] KOG2299 Ribonuclease HI  ali  100  1MSLKCETERSKTWNNFGNGIPCVLGIDEAGRGPVLGPMVYAAAISPLDQNVELKNLGVDDSKALNEAKREEIFNKMNEDEDIQQIIAYALRCLSPELISCSMLKRQKYSLNEVSHEAAITLIRDALACNVNVVEIKVDTVGPKATYQAKLEKLFPGISICVTEKADSLFPIVSAASIAAKVTRDSRLRNWQFREKNIKVPDAGYGSGYPGDPNTKKFLQLSVEPVFGFCSLVRSSWKTASTIVEKRCVPGSWEDDEEEGKSQSKRMTSWMVPKNETEVVPKRNVYFKERHMSNILTF 297
2 -71.400[L] COG0164 Ribonuclease HII  ali follow..  23  1..........MSETFIYPQANLIAGVDEVGRGPLVGAVVTAAVILDPNRPIV----GLADSKKLSEKRRLSLYDEITE-----KALSWSLGRAEPEEIDQLNILHATMLAMQRAVSGL----------HIVPDYVLIDGNRCPKL----------QMPSLAVVKGDSRVAEISAASILAKVTRDREMTELDLLFPEYGF---AQHKGYPTAFHLEKLAA------LGATVHHRRSFGPVKRVLG..................................................... 196
3 -61.900[L] COG1039 Ribonuclease HIII  ali follow..  18  57.AEKLASDFGHIAQVVPQKQTNLIGTDEVGNGSYFGGLMVTASFVSEENLNFLKEIGVADSKKLTDEKICQIAPKLIDR------IPHVALVVEPAKYNEVIASGYNAVIKVALHNQAIYLLEKQL--GHKPENIVIDAFTTEANYKKYVNKEHPLTKVTLLTKAEDQFLAVAVSSIISRYLFLENLKKLSKESG----FTLPSGAGNLSDKIAAQIIKSQ--GVDALNQLAKLHFANTQKAIKIAQL................................................. 292
4 -7.100[R] COG1159 GTPase  ali follow..  11  1..........MSTDKTYCGFIAIVGRPNVGKSTLLNKLL--SITSRKAQTTRHRIVGI-DTPGLHMEEKRAINRLMNKAAGDVELVIFVVEGTRWTPDDEMVLNKLRNKVDNVQEKVDLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELP...................................................................................................... 211
5 -6.880[H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase  ali follow..  14  4................KNRSVFILGGARSGKSRFAEELAGKA----GGRLHYLATGRAWDDESHHQERRGGEWTTHEAPVDIATVLQRLDSPDSVILIDCLTLWLTNLMMENADMETAFAELEAAIVSTRAKLILVSNEVGLGIVPENRMAREFRDLHQRVAAIAGEVYFVAAGLPLKMK..................................................................................................................... 172
6 -6.270[S] COG2410 Uncharacterized conserved protein  ali follow..  1.....................MYCGIDVGLKKC------AALISDRLEFVGDYTELDLDNVRVTGIDAPLSFPAKGSLRECERLLLKMGIRLFPSGAPFFRGIALRGMEIAEELRSKGVEVYEVYPYATRVILNIAPKAKKHTKSGLEEIRAELSRWVEIPELSHDEVDAVIAA--LTVKLFSEGMGVKLEGI------------DGSPKGRVQLS................................................................................. 179
7 -6.100[O] COG5046 Protein involved in Mod5 protein sorting  ali follow..  1......................MAG----GTG-------------QRDAGTSLEKQPRADEENVFSPQKQHLVLGALDRGACQHQIYVLVKSLQSSCVCLSTLRLDLHPLLQIHLQKAERVEHPGKWGSGAGASCGPAGRRQGQGCRHSSAGIYGALELGCISKTNKLFQKLQDLNPLLNIEIEALLSALELRFPDYDFCGESWGS-----NEMTYSISTTHKNSDDVKEFVGFLEVILHRSVSLGGCEIFSYENRMGPFEDCLWYFSFLFFNKK----QRRVVMLNAFMSRS.... 283
8 -5.930[H] COG3172 Predicted ATPase/kinase involved in NAD metabolism  ali follow..  12  12.....................AILGGESSGKSTLVNKLAFNTTSAWEYGRDYVFSHLGGDEIALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALIDEYRPWVADGLRSLGSSVDRKEFQNLLVEMLEEN--NIEFVRVEEEDYDSRFLRCVELVREMMGEQ................................................................................................................ 186
9 -5.800[F] COG1618 Predicted nucleotide kinase  ali follow..  16  108......................LVVIDEIGPMELISQSFVSAVVLHHSSRHPLAQRFRKGFETVDKGNRDELPEKITN........................................................................................................................................................................................................................... 177
10 -5.660[S] COG1628 Uncharacterized conserved protein  ali follow..  11  1..........MDLDFHIKPEIRVLGIDDSEKVMIVGTVFRGGDWMDGVLRSEITRDGLDATEVIST-----MIKNSRHYAQLRIVMLDGVTYGGFNVVDIEELYRETVMRAYPDFEKIRAALRHFSDGELRWEIIKKAGKIEKLVTEKNGTPIYIQKAGIGLKSAEKIVRLTSIRSNIPEPLR.................................................................................................................. 178

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 4 7 0   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Wooley JC, Godzik A. Probing metagenomics by rapid cluster analysis of very large datasets. PLoS ONE. 2008;3(10):e3375. Epub 2008 Oct 10.