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Query: [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAPAKKREKDSNPDGSAANGIIGLTHGAPDASNAGSTVPPTAEGQVKLNGHQQEQELFLQAFEKPTQIYRYLRNRHETNPIFLNRTLSYMKERMSRNNKKRISFQVNSMLESITQKSEAVSQNYLHVIYDSLHEKLPARLDNESGEDLLQEQLLCEAGESVSVETTLYKITRSKRKDSTLDFQELLSKCSQIVYNPKDRVGEHATISIPLQTMRPMGEQHTLYKLLFRIKVLSPSTCNDENAETPPNKRSRPNEKMFGSELILYEKSSGFITEGEYEAMLQPLNSTSIKSFSPKKCTWETMPDSYIPLSLTYDVYQQSPMLKFHLTLSNEQLPEMISAPELQRYVQHLDAVAEMNYNNNNYNNNNNCSGLKNGSGGGNSTVCKTTPEHIQIVYNFMYSNNTRQQTEYTQELNCPWCGLDCLRLYALLKHLKLCHARFNFTYQPAGSGARIDVTINDAYDGSYAGSPYDLAGPSGSSFARTCGPVRRTSVTSLMVCRPRRQKTCLDEFLELDEDEISNQRSYITGHNRLYHHTETCLPVHPKELDIDSEGESDPLWLRQKTIQMIDEFSDVNEGEKELMKLWNLHVMRHGFVGDCQLPIACEMFLDAKGTEIVRKNLYRNFILHMCSLFDYGLIAAETVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAPHRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHRPPPPPPPQLast
1 -223.000[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali  100  1MAPAKKREKDSNPDGSAANGIIGLTHGAPDASNAGSTVPPTAEGQVKLNGHQQEQELFLQAFEKPTQIYRYLRNRHETNPIFLNRTLSYMKERMSRNNKKRISFQVNSMLESITQKSEAVSQNYLHVIYDSLHEKLPARLDNESGEDLLQEQLLCEAGESVSVETTLYKITRSKRKDSTLDFQELLSKCSQIVYNPKDRVGEHATISIPLQTMRPMGEQHTLYKLLFRIKVLSPSTCNDENAETPPNKRSRPNEKMFGSELILYEKSSGFITEGEYEAMLQPLNSTSIKSFSPKKCTWETMPDSYIPLSLTYDVYQQSPMLKFHLTLSNEQLPEMISAPELQRYVQHLDAVAEMNYNNNNYNNNNNCSGLKNGSGGGNSTVCKTTPEHIQIVYNFMYSNNTRQQTEYTQELNCPWCGLDCLRLYALLKHLKLCHARFNFTYQPAGSGARIDVTINDAYDGSYAGSPYDLAGPSGSSFARTCGPVRRTSVTSLMVCRPRRQKTCLDEFLELDEDEISNQRSYITGHNRLYHHTETCLPVHPKELDIDSEGESDPLWLRQKTIQMIDEFSDVNEGEKELMKLWNLHVMRHGFVGDCQLPIACEMFLDAKGTEIVRKNLYRNFILHMCSLFDYGLIAAETVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAPHRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHRPPPPPPPQ 955
2 -26.900[Z] KOG4462 WASP-interacting protein VRP1/WIP, contains WH2 domain  ali follow..  2...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................APAPPPPPPAPAPAAAAPAPPLMTGDRSALLNSIQKGKKLKKATTNDRSAPVVGGGVVGERKSNTPKSFAAPPVPTGAPSLPTSSNNTQQAEERPSMPALGGLFAGGMPKLRHIGKSSASAAPPSAPAPPTPQSELRPPTSAPPRPSIPPPSPASAPPIPSKAPPIPSSLPPPAQPAAPVKSPPSAPSLPSAVPPMPPKVPPPPLSQAPVANTSSRPSSFAPPAGHAPNVTSESPKFPNRGPSIPSASVPPVPPSSYVLQQRPNRVDDHGRFHFKDDSYLPIPH 285
3 -25.300[TU] KOG3895 Synaptic vesicle protein Synapsin  ali follow..  567.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PSSAGPGSGFSSSFLGKQFSFAGKGEGVISTQPTQRPSEEPPAIPTTASSAVRPESSVSVSDSRNTDTLTERAGAGYQPVTNYEQQERVNPFDKEPSKSGSAASIHTSSSSSISSSSISSRINRNGNAIQSPPPPAGPPPPPPTNVTAVGSNANSSSGYRNSFSSSLSKDKTSYGNYGSTTSVETITRMDTNTTNIGATATEAGEASGVTAITNISNSDGIVAPTTGTITTSVTTNDWRSAIGMRSASVYSAPAAVTTVLPGDTSGYDSNSIASQGEGLNNPSDLPSYTRPSYSRSESNASKHSD. 871
4 -21.700[K] KOG0709 CREB/ATF family transcription factor  ali follow..  279.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KAEER-DLKRIRRKIRNKRSAQTSKQDYIE------LEDRVSE--------IERLSSENQSVISQ------LKKLQAQLGQNAKRTTQAGRCLAVF----QLSPLGNQDNQKVLECIEEACQPSATSMNSANSAQRAIAGVTAPSVVIPSGGPVMVSTNANRQMNRNAVLNHHNNSKYPASGNQNHHPIALEDLNHPPPTLQPKQSYQQQHQPSMYRRSDETIAMAMAKIGARKGSSTSSSSASSVASSTSTSSATSPIYRTSRTLGAFEDQCDASSDDSNCANMPSLVPMKMSAQPPKRKIVTMNGQPRVTYRAVPASSVNVEQAQYYKVPQQKVQYVTMDRPIKYEVLNDYIKMEEESTIRLPNSWSTAGPRLHPQVNASSRTVRPLTVATPVHYNGPSAKKIK 684
5 -20.100[R] KOG0562 Predicted hydrolase (HIT family)  ali follow..  175........................................................................................................................................................................................................................................................................................................................................................................................................................KPLICNQCEFVARNLPSLKGHLVGHLQD---------------------------------------------KSVCQRVRLGNQFFPTAGYRTSELAYCFDFVDFYEYKKQMEVDKLAYIRDELQRKLNDKRNFLIESDRKSQYHFRV---KEEFRDITQLTEAQLPLLD---------------HMMDLANQIIEKQKH---SRNFLIGF-LNL------HVISNDPFQIAYMMLSVQGSIESISEETYNNLQEKTPLRCNQCEFVTNMLLDLKAHLYQHWQRKEDERDQKKKVDKIIQMISETKLDEAEAKPKLLNEEEPIQAQPVAAIAQYPNEHLGKPLTPQQQPGKQQAQNVYDKNINGPSVNMMNQNNPNNPFRNTPHLNRQSQKPPHPRSGPRGPMAPWTGPRFPCHQQQNRFRPPGFNACRQPYPPYHSGHQQFPNASSVGGGQTGLPGQGQGPRPKWNSNKIFNQQNRQNTVQAQPQAQNQQTNQQQIQNSNKNQTPKKKPWKNRLQPVGKVQNQGGANRDPAPPSNSKPS...... 685
6 -20.000[U] KOG1091 Ypt/Rab-specific GTPase-activating protein GYP6  ali follow..  305........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ILAVVDSSLHSHLVELGVEPQ------------RWLR-------REFL------QDLLLVWDEIILADNSARTDLVLGMTVSMILYLRSSLLSTENATCCLQRLLNFPENIDLN-KIIQKAKLLQALVLDTDMLSALSINGVFDQSNFVPARTKSCSTSPRSPLIIAPESYWEKKWRVLHKAEEEENKICLEKQTPPTQKKKRWLNVTKLFRAVIDLSHHKLGIGERKANSSPVTQSLLEDSSEQLNVDCHVTVNKENIHPQETEENIMEFHSADEESIVSGSSPSEESSFVSLDPTSSSAGSNLLPDEDDKSIVSISEENSSVSSDPISPAIDSNYSGKYLDCCTGSENDKDQQTSVNSPLSVSPHRRNEYPVTQSDEDVSTDKSVGITKEYKLLHGIVQWFRKLKRTLSSEETSHRKASDATKTNDVKIKKNQ 752
7 -19.900[U] KOG3834 Golgi reassembly stacking protein GRASP65, contains PDZ domain  ali follow..  203.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PTQPPSYHKKPPGTPPPSALPLGAPPPDALPPGPTPEDSPSLETGSRQSDYMEALLQAPGSSMEDPLPGPGSPSHSAPDPDGLPHFMETPLQPPPPVQRVMDPGFLDVSGISLLDNSNASVWPSLPSSTELTTTAVSTSGPEDICSSSSSHERGGEATWSGSEFEVSFLDSPGAQAQADHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPASTEGLDTGTEAEGLDSQAQISTTE 440
8 -19.700[R] KOG3253 Predicted alpha/beta hydrolase  ali follow..  12  365....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TQSMVDRCIQDEIVDFLTGVLTRAEGHMGSEPRDQDAEKKKKPRDVARRDLAFEVPERGSRPASPAAKLPASPSGSEDLSSVSSSPTSSPKTKVTTVTSAQKSSQIGSSQLLKRHVQRTEAVLTHKQAQVPISSEPPEEGEKEDLRVQLKRHHPSSPLPGSKTSKRPKIKVSLISQGDTAGGPCAPSQGSAPEAAGGKPITMTLGQASAGAKELTGLLTTAKSSSSEGGVSASPVPSVVSSSTAPSALHTLQSRLVATSPGSSLPGATSASSLLQGLSFSLQDISSKTSGLPANPSPGPAPQATSVKLPTPMQSLGAITTGTSTIVR 691
9 -19.600[S] KOG4502 Predicted membrane protein  ali follow..  82.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NSATITEEMARIRNSIEDISEFSLDSNEVDEAINDITVPYGTKMKKSSKFAELSEIHNTDSSNKALPPFAFSEDQQESVDVVEKVEAVPPTTTTTKLTTLPSTTQSTTTRTTTQPSTIVSTRQKYVNVDGDIYVPGKTVISVSSTPIVDRTGTTTPVSIEISTTTLPPMTEIFTTKYSTLSTSYTHTPSPHIFSSSTVRLPIAIPIPTKLPEIMFTTPRPYRGPFITEFTIEPKRSEGRTSLRDRIRSTSQLLNLLGDKIGGIDQKAAGNRAEPKTGVLTNIYDQGVIKKRNLKTKQWGIAGEDPQ 387
10 -19.400[Y] KOG2992 Nucleolar GTPase/ATPase p130  ali follow..  121.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TPAKAVGKKAKSSSEDSSSEEEAPKKAAPVKAPPAKAAPAKKVESSSEDSSSEEEPAKPAVKATTTKVAPAKKADSSSEESSSDEETKPAAKPVAKAAPAKKAASSSEESDSDDEPAAKKPAVQPAAKPAPKAAASSSEDSSSEEEVKPAAKSAAKLAPAKKGASSSDDSSSEDEAPKKAATLAKPISKAAPTKKADSSTEDSSSEDDAPKKVAPAKATPAKAIPAKKAASSDDSSSEEEAPKKAAPAKATPAKATPAKKAASSDDSSSEEEAPKKAAAPAKATPAKKAKSSSEDSDSDEEEAPKK 426
11 -19.200[LKR] KOG4594 Sequence-specific single-stranded-DNA-binding protein  ali follow..  14.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SDSQAREKLALYVYE-YLLHVG------AQKSAQTFLSEKNITLGEPP---------------GFLHS------------------------------DLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPRGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMT. 358
12 -18.800[O] KOG2231 Predicted E3 ubiquitin ligase  ali follow..  117..................................................................................................................................................................................................................................................................................................................................................................................................KKYRIGFC---TAEIRQQFFKLLDHPCPKCDAPYRTFEGLRNHVRSEHKLLYCDLCVETLNI---------------------------------------------------------------------------TFERRCY---TQAELQLHNTKGDPDNDRDELFRHLRREHYFCHFCD-ADGCNEFYNDYAEHFRAEHFLGKCATEQFVGAFANVHGKSLNKQQAKQTRTLQVEITLGPRGRSGQTEQGITSVRTRNDEHNDYQNDLPSITQRHVSIDAGNEEQFPTLRGASTAPSVSLVRPPPPSMRNLSGTSGLARTKENFPALGGGNGGGVTGPTSSSIAARAAQSQHPVAAVFKKPTSAAGSGSRSGPPGNGMLLHVSNRSAAVPKKAATPQVDFPALPGKGNKKNLRNLEEDMLPSGSPVPMANISAKHRSLADDYVSVASPSTFQKLQMVQKEEDEAKARQEALKKSAPKLTAAEFPSLGPSASASSSRTTAPKPSSGSPSLNWSKPANEKKQRELENRKAKVAPAPVLPSPTSKPAPKASNNNVQEQQANKKDKKQK 638
13 -18.700[R] KOG4377 Zn-finger protein  ali follow..  2.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PKAQHSPQAIFTSFKLERSEYSGPGARLPGGSSSTVATAEDRLSLADHDGSATDLTPSRYRKRGRVWAPTSSLEQPSKRIVNQPTHFGARSETESRSSRHESLAQPTLQPPLETNSSTNLSSTILDKVSVVRAAGTFYPENANSAAQGETPEVVSSRYNSRQESNDLEVDQPEDLSMRPSLPEATATPAVVGPALNMNLLQFKQLIDLYQRQVLLPSFLAAASQPLALPGSAAGPGVSGPLLDMRILLENAAQQKLMLLNAAASATASAVAATT 277
14 -18.400[R] COG5236 Uncharacterized conserved protein, contains RING Zn-finger  ali follow..  138............................................................................................................................................................................................................................................................................................................................................................................................................TSEEVATETLNLLKFFCPLSVCDFGSFKKYNEHLKSEHNRM-FPCELE-TQNQLRNHQTKGNSEGFKGHPM---------------------------------------------------------SGKRFY----------------SDDEL------YIHMRNQHEKCHINPASPQYFKDYNDHFKHSHYVCT--LDNKFVVFLQAHIL-----------QEHGNILKGKPKFFQSELSTFISAPSRVIRERDDYDLPSISSLPGSSSGSRTDVRSASSPEESRLRLAERAKYYLENSKEDFNKFSSYNEDYSKGRLSAEKLLESYKLLFTKPNADVYLLIHNLAETFPKNSSKYNNLNAIYEQREQTLARQTSLPSLSSDSSLSMSIGRGHWGGTNDGGSAGAALGVRNIKNLPTLKSPSASYDPFATTVKKNTLRPVQNIKRTTPQSVSYRTSTNTVAFSPTYLESKKGSSSTSLNNSKDKLKSLNLPQLPPPKPKVQIPGLNRPQIADPKQWGKKSSTQDTNVHDNLRELNTTSGGNKKKGKQK........ 631
15 -18.400[S] KOG4511 Uncharacterized conserved protein  ali follow..  16.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SDDASRKQKKLLSK----------------EFITIWSIPIAS-------FIESQSVVFDRQQMETDVYIMIHKEYSQLIDTLIEVPMMMRKNIEQALQMIERHSKDEYDSMQKGSEELEMMAQNSRIQREALEQEIRKEEILLQQALDEGARAQNQNQNQGTSSTQTDGVNAPLRSVAAMMAATFAIDTATSTDDVTYKFLDQSTGTMTSSTGVSVGTLTNTGVSSGTMTSGVDTGTDADGTVGRPKSAKRVGSAVGKRSVSKGTPSEDAKKSSGSSSPDEAEKSKRERPGTSVKKAIGIVAANSEMSSNGTQMDVPVDEEGTKKRPGTTSKKSIATVTASPEMSSKTTQMEPEQDGEGKKRPETSKGANERKYSNAGLEDIVGPKSSPHEEKKSSHPSSRKGSKATDEN 492
16 -18.200[TZ] KOG3671 Actin regulatory protein (Wiskott-Aldrich syndrome protein)  ali follow..  33.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LNSQENEMLF---ALVGSEAVC----LTAAVVQLKSDRGAWLVKDYAQRAYFLRIFDILEERIVWDFKLYK-LNFFSEYEAAEFKEHLERRHAQERKSTSTTRPAHPGMPIVVSSGIGSTPTRQFEITQAYGGTIRGPPMAIGGGQGITQMGTMAAAPQSHTHTDGNASSSGSWFRKDKNKKKDKKSKIKKEDISNPTNKAAGLESNNLNEDDAKNYDKYVSVGSLDPSQISSPLPPPIQQHPQMNQSWNQTPVRQYKPSFPSSAPIGSGASSYSTPAAPPPPTRVESHGLAPARPPPPPPSSGTRGIAPSRPLPQAPNYGTPENRPHAVPPPPPPPPPQSFGMAPISSAAPPPPPPPPPMGLPAVGAGAPPPPPPPPPSGAGGPA 490
17 -18.200[U] KOG1955 Ral-GTPase effector RALBP1  ali follow..  211..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TTAIEIRRQSSSYDDPWK-------------ITDEQRQY---YVNQFKTIQPDLNGFIPGSAAKFTKSK---LPILELSHIW--ELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPAASNVNDEQDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVR 652
18 -18.200[O] KOG4275 Predicted E3 ubiquitin ligase  ali follow..  10....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FTVFRRKRA--IASRRCKRCSVFAQRSRTDLLKLKPK-DLIFYLQHISTEGCLEKE---ELVGLVLTHVAQVDRSRGSNASSNSPGRGQANPIDSLKQSCQNFFSNLSDNISDSLASFDSKVTTKPPESRQPEVPTHIFEQPRVSTREIPTYASAVNGGPQHVHVQQQATTTNGGSQSSSSPSTSTQSSNNRDASSSSQAHVAHQEARNEEQEDAQSKSDCECSDEEIMATFSERVSISLKTDTSGRRVNAAAEPSPVDLANVDNGPAGNTAPSPGCSKPGSSSSKADASSQSSFEELGAIGGISDESKANTDTNSSHLDQWQVLEVNRIEAVEETPTTSAADEILEVTLRSRPAVEGDDSEMGESTQALNVNQR 394
19 -17.900[K] KOG3227 Calcium-responsive transcription coactivator  ali follow..  22....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PAAIQKMLDDNNHLIQC----------IMDSQNKGKTSEQMLHTNLVYLATIADSNQNMQSLLPAPPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMTMSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQPDGNSQYGQQQDAYQGPPPQQGYPPQQQQYPGQQGYPGQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQR 377
20 -17.800[S] KOG4791 Uncharacterized conserved protein  ali follow..  467.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QEVHMKTVEEIKLEKALRVQQSSESSTSSPSQHEATPGARLLLRITKRTWRKEEKKLQEGNEVDFLSRVRMEATEASVETTGVDITKIQVKRCEIMRETRMQKQQEREKSVLTPLQGDVASCNTQVAEKPVLTAVPGITWHLTKQLPTKSSQKVEVETSGIADSLLNVKWSAQTLEKRGEAKPTVNVKQSVVKVVSSPKLAPKRKAVEMHPAVTAAVKPLSSSSVLQEPPAKKAAVDAVVLLDSEDKSVTVPEAENPRDSLVLPPTQSSSDSSPPEVSGPSSSQMSMKTRRLSSASTGKPPLSV...... 770
21 -17.200[S] KOG4556 Predicted membrane protein  ali follow..  31..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................WV-------ISGLFGATQKRRPLLYTINVLIF-------RFTPYCDAEFDVIRKKWVQKQCLIPFYSVEASQAILHIIFAIVTSIFSILVIVELRKKPIRSNSQSINHYAQICASKVAKAPSSTNNSSSGYLNSQYDDLGSSREKVKVTEKKEVKGQFERNSKKKKKNPRPEMPAPDCAPCSSNRSSEEESNLEDVYTQPIKKKIMPLRRPDLEEENRGTNVTSLVSFDPKSATLLRIRQHLEAEPSDRDTPDYDMYERLRSRSSGHSEVAPASTIPLSSDYKSRNASQDSVPSMFAPMLNSPAPSSTTSSSSRTSGASLAHKTHIVGKGGISLSTVDPSPILSPGIRLSEQLGAKNQSYKSAFRVQKTENARVISHYHAPNEIPLSSDPSVVENESNYP. 466
22 -17.000[R] KOG2295 C2H2 Zn-finger protein  ali follow..  159.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KQFLDTQDENISDSEVMRKYTEYKTD-------FKRQQLNEFFVAHKEWFKNKRRTDVFMELLEN-IGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSS.................................................. 516
23 -17.000[TZ] KOG4035 Coeffector of mDia Rho GTPase, regulates actin polymerization and cell adhesion turnover  ali follow..  3..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KALYDFQAVYPFDEGEYFI-QTSARQRNWWQVVSMK----------GNIGFV---SNYVMKIK-------HDFLISFLNSSIESLEKCTDHE-----------NGIMSKDELLDRLREKKHTMERLYAESSERDGDSSLSYSHSYSDKGSHRHSHPHPTQSQTQLHSQHRQHSPPPSGGSVGSQRLDMSKKSMSSPAVGSSCGLPQNQGMIESPSMGSMQFQGSSCTIQTPQQQQPLPAPPAPAPSPSAASATPTAASTSKAATGGDVAQDNSITSEPSETTTTTTTTSEDVVTTYKETSQMSTSQQHKPQNGSTASASISASASASALRSNGGNGKANGSATALHQELQQEEADSAPDKSDDASAVQSDDGCPANGDSADNSQALDSIDSPSHRQRGLSLGRIEEGATGGGQLKVESSDVYQ...... 403
24 -16.700[K] KOG4477 RING1 interactor RYBP and related Zn-finger-containing proteins  ali follow..  101.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ATRELSEGVSTKEVKIEEPDIASEKPRTPVPEKQEEVSVENVEIEKCETPTKSKSATAKPPSAKKLTKRTDEDKKSSVATKKAKTTEESVPHIESNVNTELVKEENKKPTPEDSIGPVSSDSLTTNQGEDQSTAQTASTSAPSVVLLPEPTPKISVAETMVVPKALPASIAIPSTSTASVSTHPTEKPKEDSILQHLPERIVKKLNQPSSLNYDLLKVHKRMTGIDPIVAESEAVLLPQDWNRQKVMKELTASFGGNQALSPTTSRQSSETDSSSSEGNRSFETPLNDASIFNSKSCQIPDREAAQ 410
25 -16.500[Z] KOG1830 Wiskott Aldrich syndrome proteins  ali follow..  2...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PLVKRNIEPGALPEGITSELE---TNSTLAAIIRQLSSLSKHAEDIFG-----LFNEANNFYIRANSLQDRIDRLAVK-LQDINMKKAF--KSSTVQDQQVVSKNSIPNPVAILTPYRDDKKDGLKFYTDPKEKMLQDTEDKRKEKRRQKEQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGASSEGSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSD........... 443
26 -16.500[R] KOG2893 Zn finger protein  ali follow..  12  1.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MGRKKKKQLKPWCWYCNRD--------------FDDEK---LIQHQKAKHFKCHICKLYT-GLVHKETIDAVPNAIPGRTDIELE----MEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQ 378
27 -16.400[DK] KOG4333 Nuclear DEAF-1 related transcriptional regulator (suppressin) and related SAND domain proteins  ali follow..  122.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KFNDQLIS-------KHFVHLAGKSTL--KDWKRAIRLGG--------------------------------IMLRKMMDSGQID----TKFDLLISSARAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLEWNSALTAAVTMATEEGVKKDSEEISEDTLMQAPFQVTDAAVLNNVAHTFGLMDTVKKVLDNRRNQVEQGEEQFLYTLTDLERQLEEQKKQGQDHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQVSSAKSSSPDTVTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTE.. 536
28 -16.300[U] KOG2724 Nuclear pore complex component NPAP60L/NUP50  ali follow..  10.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SEQQMNMFRLMSLLNA------------------EFLKVINGYFTESGTMKSYMDHVAQL-----------KQIYKVDDDVAADMTVPRRTENSSESSGETVAPRKIAKAVRKNGTPKNPLNSTVFAASSPAATVASVPKFGDISVITKETPAPLAKTAEPLVAPAAPATARKRAIRGGGPLGGAESVVFKSGEDGQAATSSVKIPATTIKFPEPTKDFWTKKSDAPAAPSNSGSLFAFLGKELFSIKKNPPIYQNFSGDKPKETPKFSGFSFGKKPAEPSEEPKAADSTPKSPKEADLPKPASSLFGASPSKPLVFGGSSADSTTSAPKPFSALSTAASLFGSSSASTTTTATQPLSFGSSSTGGSSLFSGFAGLAQKAMENQNQAK 381
29 -16.100[S] COG3266 Uncharacterized protein conserved in bacteria  ali follow..  1....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MDEFKPEDELKPDPSDRRTGRSRQSSERDSEPQINFDDVDLDADDRRPTRTRKARSEEPEVEEEYESDEDDTVDEERVERRPRKRKKAAHKPASRQYMMMGVGVLVLLLLIIGIGSALKAPSTSSSEPSASGEKSIDLSGNAADQANATQPAPGATSAEQTAGNTSQDISLPPISSTPTQGQSPVVADGQQRVEVQGDLNNALTQNPEQMNNVAVNSTLPTEPATVAPVRNGSTTRQAAVSEPAERHTTRPERKQAVIEPKKPQTTAKTTTAEPKKPVAPVKRTEPAAPAATPKATTTTAAPTATASAAP. 310
30 -16.000[Z] KOG3756 Pinin (desmosome-associated protein)  ali follow..  408.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TNRVESVEPSENEASKELEPEMEFEIEPDKECKTLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
31 -15.800[MOU] KOG2629 Peroxisomal membrane anchor protein (peroxin)  ali follow..  10  1.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................REDQIQNAIKFLSHPRVRGS-------RSFLERKG--LTKEEIDEAFRR-TAVFIKRSLIEETDPLKKADAKPSLAEEAVAAAKAASAAASDVARVSQEMMITKNEERKYFEDLTHLLGVQVQEMKSLSNNIRKLEGQSNNIPKIYSADQEVYNGSVTTARKPYTNGSNVDYDTRSARSASPPAAPADSSAPPHPKSYMDIMSMIQRGEKPSNIREINDMPPNPNQPLSDPRIAPKSKPWDYGQAPQDESSNGQWWQQKNPRSTDFGYETTTAARFTANQNETSTMEPAAFQRQRSWVPPQPPPVAMAEAVEA----RRPKPQAKIDQEAAASDGQSGVSDELQKITKFSESGGDGSGGIKIAEIQEETEQQHISQEG.... 453
32 -15.400[T] KOG1701 Focal adhesion adaptor protein Paxillin and related LIM proteins  ali follow..  10  8.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PPKSTGEPLGHVPARMETTHSFGNPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLDDSSALPSISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPG. 280
33 -15.400[UW] COG5295 Autotransporter adhesin  ali follow..  2.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NKIFKVIWNP---------------ATGNYT-------------------------------------------------VTSETAKSRGKKSGRSKLLISALVAGGMLSSFGALANAGNDNGQGVDYGSGSAGDGWVAIGKGAKANTFMNTSGSSTAVGYDAIAEGQYSSAIGSKTHAIGGASMAFGVSAISEGDRSIALGASSYSLGQYSMALGRYSKALGKLSIAMGDSSKAEGANAIALGNATKATEIMSIALGDTANASKAYSMALGASSVASEENAIAIGAETEAAENATAIGNNAKAKGTNSMAMGFGSLADKVNTIALGNGSQALADNAIAIGQGNKADGVDAIALGNGSQSRGLNTIALGTASNATGD..... 314
34 -15.200[S] KOG3930 Uncharacterized conserved protein  ali follow..  9....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................WVKFFNAAGI------SPAAAGYAHV----FVENRIQDDMLLDLNKLREMGITLMGDIIAILRHSKTVCEQNAREQVLTTEVVQSVVRPVSPKPKAPVATPKAKVYPPAKPARRVLPEHEGKYKVTLPSGTTERSKQILAKREKLYSDRVSSSKKSDIFTRLHAEDEAQEGIVSSSGESSVRVHVAGASKTAATSSNNSVFARLGGKQGALPEEFTSTREIKSILKNTHRTVGGGGGGGGVTKNSPIVKAKKVAAVTQQKVMLVHKVPLKKGDDDDDSMDDFESDEEDYMSSGEDFDMGAGEKKFASTAEVREIVPESAYKNRQGKSFANNIKSRLGMVSKLHATKKTYNLKASPARKPQARLSPVKGKT..... 373
35 -15.100[B] KOG2748 Uncharacterized conserved protein, contains chromo domain  ali follow..  2.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ELPAVGEHVFAVESIEKK------IRKGRVEYLVKWNTWEPEENIL-----PRLLIAFQNRERQEQLMGYRKRG--------------KPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQYELNSKKHHQYQPHSKEGKPRPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEAPSPTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGPPNGMMPAPKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAADERHPPADRTFKKAAGAEEKKVEAPPKRREEEVSGVSDPQPQDAGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHHHH 396
36 -15.100[KTDL] KOG2043 Signaling protein SWIFT and related BRCT domain proteins  ali follow..  71......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VKPSWVILQCGTLLPVLSQVSSEDRSALWA-------------TFYGGDCQLTLNKKCTHLIVPEPKGEKYECALKRASIKIVTPDWVLDCVSEKTKKDEAFYHPRLIIYEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHR 483
37 -15.000[R] KOG3175 Protein phosphatase 4 regulatory subunit 2 related protein  ali follow..  4.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ERLQEALKDFEKRGKKEDQFLC-WSQ-----KGYFIFKLEKVMDDFRTSAPE----DEMKERILKIVTGFNG-------TIQRLCELLTDPRRNYTGTDKFLRG--EKNVMVVSCVYPSSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
38 -15.000[K] KOG4319 DNA-binding nuclear protein p8  ali follow..  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MRRRFLLPVHGPQQRNVLDG--------LLAELETFFRTNRNSRRSGWVFQESACADAWPQTAGQCQQAGPQAQTRPPTPISYKEELYRCLYYYCLRYFPACGVGRSKGLTLSEQALRTKRLSPGGHASRRICCHHWGTLAQECSSMGAGGTQGVALAMARGCCCLGMTWSEKVVGGNEKALAGQKQPCGVPEWQQARAARVIHPRDSYEKPRPTERHSVQSTADEKATTPKRVPSFPTFRVFRGEPVWVPQCLKGSREAVPGAVAQCAAVAWRAPHQTMAMASQAWKPGPVPATTFHAPLAQVQVLASRSSGAAQVHGTRPCTELPAMSLSLPLRYTPE 338
39 -14.800[K] KOG4796 RNA polymerase II elongation factor  ali follow..  276...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SEIDRRSLESVLSRKLNPSQNATGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPD 527
40 -14.500[R] KOG0041 Predicted Ca2+-binding protein, EF-Hand protein superfamily  ali follow..  10  187.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VDVLDQIMSSPPPPPTSPPQLPPTPPARITSVRSDESIEEEERRRKESEETASFEELEAEIMRISRSPVPPPVLSIPPPPPPNIPLPTIPQEVQSPPSPRPTSVPPPIPSPGPSEDVNMDELIESFSDSVIFNNSMSPPPPLPPLRESSLETLEVTPEDPVTESKVEASPTPLPKATESLNESSIKALEGLEVKALEAQEASDDRPSAPTPIRDSSLPPPPPPKPETPLAIRRAGPIPTPQLLEMIHQEDCSIRPSSPTSVSHGSRPQSPAVPKKPSVTVSPLGLLCDPNLSIEKPEEMKTEDTKPVETAPAP. 499
41 -14.500[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  4...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IIRLKNLTAGASDVRTFFTGLIPDGAVIIGGDEGEVFVGFSS-------DDDARLAMTKDRLMIHGAEVLFLSSKSEQNSVIAA------RKNNTYTSPVYKEYVPPVPSQPTPAQEQNWNSQTAGNPYAAKAGYEASYPPQNSNATRTSFNNQNSYSNRQEISQNHQENSVKLKDPFGGDYGGYKFQQQPPPQINRYGSGPPPSKPADLSNTRSLPPVNNPPPPHPIPQFPPEKQFGNKLGNNNDVSSRENHIQGSGNERVQGGDSWRDTSFNQPPRNDFKGNYNNAYSSNKYKNNYKAPEFNNDFNGGNKFNQFPPRNAQSTDLSENRAAPPQTGRKTLMPTPQAPFQNAPAPFTNGPSDDVNRPFQTGPPGNLGRNGPPPFQAGVPPP. 386
42 -14.400[T] KOG2381 Phosphatidylinositol 4-kinase  ali follow..  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SGARDQTDPPLLQLEDEVDLIGDFAKDQPPPRNQLSPLLNGFESTSNQLTTKVEINTVGMGKRKTRRRGKKAREPMLLSVDDEDDEEEAQEERNHTNGLPPGEESAGGDAVIQKPQLDNLVMHYDDQIDDEDGEEAVLLKRSSNPRNQRLKGSAEDSIDSSSQQPPIICHIAPAKVASSALTSPLKTTSHTALARHPHDEADDICLVPEIDFEGMSTDAGSDNRESQPLLGGGNASHGSRISELLGGLGRGHDHVEFVSNTFGAKYQEPSEPRDDEQPTTSKDALESSSSVPSASAAYACIC.. 303
43 -14.300[L] COG5055 Recombination DNA repair protein (RAD52 pathway)  ali follow..  72........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NGWSSSIRSINV-DFMDENKENGRISLGLSVIVRKKEGTTDA-LKRALRNFGNSLGNCMYDKY----YLREVGKM------------------------------KPPTYHFDSGDLFRKTDPAARESFIKKQKTLNSTRTVNNQPLVNKGEQLAPRRAAELNDEQTREIEMYADEELDNIFVEDDIIAHLAVAEDTAHPAANNHHSEKAGTQINNKDKGSHNSAKPVQRSHTYPVAVPQNTSDSVGNAVTDTSPKTLFDPLKPNTGTPSPKFISARAAAAAEGVVSAPFTNNFNPRLDSPSIRKT-SIIDHSKSLPVQRASVLPIIKQSSQTSPVSNNSMIRDSESIINERKENIGLIGVKRSLHDSTTSHNKSDLMRTNSDPQSAMRSRENYDATVDKKAK 467
44 -14.300[L] KOG4141 DNA repair and recombination protein RAD52/RAD22  ali follow..  72........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NGWSSSIRSINV-DFMDENKENGRISLGLSVIVRKKEGTTDA-LKRALRNFGNSLGNCMYDKY----YLREVGKM------------------------------KPPTYHFDSGDLFRKTDPAARESFIKKQKTLNSTRTVNNQPLVNKGEQLAPRRAAELNDEQTREIEMYADEELDNIFVEDDIIAHLAVAEDTAHPAANNHHSEKAGTQINNKDKGSHNSAKPVQRSHTYPVAVPQNTSDSVGNAVTDTSPKTLFDPLKPNTGTPSPKFISARAAAAAEGVVSAPFTNNFNPRLDSPSIRKT-SIIDHSKSLPVQRASVLPIIKQSSQTSPVSNNSMIRDSESIINERKENIGLIGVKRSLHDSTTSHNKSDLMRTNSDPQSAMRSRENYDATVDKKAK 467
45 -14.300[R] KOG4834 Predicted DNA-binding protein, contains SANT domain  ali follow..  37...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SLSIKNRTVSQIRQALKKKAFEDAGIPAKQVPVQQVQHVLQTLPQQQPQQPLQQPPPQVFKSQPIVQHVQLVAQPKQIILHPQSNTTTTGTTVTVKQYQQMQKAAALAAAQAAASTANNTPTITENIIIQQPTSTTATVVQQPHMVSTCSSTQIVVPVVSAVSTVPTVLSPTVVIADDVVSTSNPPAAAATVGSPAGAPAGLKCGPDVSMTLNRINVQENE... 257
46 -14.300[S] KOG2465 Uncharacterized conserved protein  ali follow..  359.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AKARSENEGLDSLASEVSEIEAGDLRDDQQRPAFSASAAKLHPNPNCETHKLATGDQEKLTQESPRESTSSAPAEVAVPAVTPPPLSAAVEVTVSGDVSVTGHSSTTGCNCFGGKKCKKRWASAKNTDTPEMSEVYCPSCEDPSNESPACLAKMPDKRPTRLKPKSSILSVESELLVGKRSSFRLPSEIKRKQQGGSITRSASLSAADRRTSLPVATKRIIPPRLRTAKAKDLEKDKEKEKDKNKENDKKSSNQKVNGSATNFLAKMSPKRLKAGKEKDKDKDGNKEKEKDKFKAMDAAKKKAVNNNNPK 668
47 -14.200[L] KOG2310 DNA repair exonuclease MRE11  ali follow..  11  403............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KGRSEANIDDSERLRPEELNQQNIEALVAESNLKMEIL-------------PVNDLDVALHNFVNKDDKLAFYS------------------CVQYNLQETRGKLAKDSDAKKFEEDDLILKVGECLEERLKDRSTRPTGSSQFLST---------------GLTSENLTKGSSGIANASFSDDEDTTQMSGLAPPTRGRRGSSTANTTRGRAKAPTRGRGRGKASSAMKQTTLDSSLGFRQSQRSASAAASAAFKSASTIGEDDVDSPSSEEVEPEDFNKPDSSSEDDESTKGKGRKRPATTKRGRGRGSGTSKRGRKNESSSSLNRLLSSKDDDEDEDDEDREKKLNKSQPRVTRNYGALRR................................................... 720
48 -14.100[S] KOG4623 Uncharacterized conserved protein  ali follow..  40.....................................................................................................................................................................................................................................................................................................................................................................................................RVNCWFCNGNVRVPYQD-RNSWTCPSCE---------------QYNGFT----------------------------------KDGDYNRDITSQRDCSLGSQKNSSKGSSSICANSYYSDVLTAQPPA------PKNGLCDQNEAQRLK-SQFEPKNESRFDQE--LKVYRERLEKQFRLCSSCERHV---NKVLHEKK---KMVLSSKFLNYIIKGASLLKQPHFNRLYGRTFGKLLLYSLIYDGLKFTRFTIALLLWSGYAMGIEFLDPYISGISFILVGSFVTLVLLATNRTNLLSQVNRDESACESFHRLCADECDDETLSMLSQQLSGYSDISNSNLSMRTASVCHSPAPTISQRTIQAPASLLSLDSLHLSKQRMEQQAWSSNYGDASTVVAPRVQPAMMFQQKPMRPLESQWYRHGQSNLAQGNTFTRSTQNLLMPSRLPSINRNVGGADVSAWVAANQSVNQDLCTANLMRHYEEKQQNQLSRTSSQSSGFESQPRPEAQCGTGAATVRDSEARESQRNFAVFPPMPSPTPTITPSEYQYSRTALPQQQPTMQPGD. 663
49 -14.000[K] KOG2821 RNA polymerase II transcription elongation factor Elongin/SIII, subunit elongin A  ali follow..  10...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VEKLQARLAANPDPKKLLKYLKKLST-DILAETGVGKTVNSLRKHEHVGSFARDLVAQAEPDEQDFEKSNSRKRPRDALQKEEEMEGDYQETWKATGSRSYSPDHRQKKHRKLSELERPHKVSHGHERRDERKRCHRMSPTYSSDPESSDYGHVQSPPSCTSPHQMYVDHYRSLEEDQEPIVSHQKPGKGHSNAFQDRLGASQERHLGEPHGKGVVSQNKEHKSSHKDKRPVDAKSDEKASVVSREKSHKALSKEENRRPPSGDNAREKPPSSGVKKEKDREGSSLKKKCLPPSEAASDNHLKKPKHRDPEKAKLDKSKQGLDSFDTGKGAGDLLPKVKEKGSNNLKTPEGK 375
50 -14.000[K] KOG2652 RNA polymerase II transcription initiation factor TFIIA, large chain  ali follow..  1.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MACLNPVPKLYRSVIED-----VIEGVRNLFA-------EEG-IEEQVLKDLKQLWETKVLQSKATED-----------------FRNSIQSPLFTLQLPHSLHQTLQSSTASLVIPAGRTLPSFTTAELGTSNSSANFTFPGYPIHVPAGVTLQTVSGHLYKVNVPIMVTETSGRAGILQHPIQQVFQQLGQPSVIQTSVPQLNPWSLQATTEKSQRIETVLQQPAILPSGPVDRKHLENATSDILVSPGNEHKIVPEALLCHQESSHYISLPGVVFSPQVSQTNSDVESVLSGSASMAQNLHDESLSTSPHGALHQHVTDIQLHILKNRMYGCDSVKQPRNIEEPSNIPVSEKDSNSQVD.... 333
51 -13.800[S] COG1652 Uncharacterized protein containing LysM domain  ali follow..  26..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LPRISNDGKPIGDAINEAGNAVKNSVEMGADKAGDILSDAAEETASIADKVGRRAASATQSIKDMASLFADNKVPSDADFAAARKKVEASLKELTNIDIPESLDETTSRLITTARAAAERTTAFLRGLPDNAAAAAAQVRRLAGVFAGTDDGAPQAANPTAAPADAAQASSGTPTAGKAQPGAAQTTIDGTGDRSTDANGKATQSEEVATVSVPQSKSGELLAMVSKPGKASRVLAMPEAAPPALQPQQATPSQPSAATSETTANNTPVPSSGTAAPTAAGSTAVAPLT 357
52 -13.700[K] COG5641 GATA Zn-finger-containing transcription factor  ali follow..  141...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LW-----RRDEHGA--LCNACGLFLKLHG---KPRPI----------------LKTDVIKS-----RNRKSNTNHAHNLDNFRNQTLIAELKGDCNIESSGRKANRVTSEDKKKKSSQLLMGTSSTAKISKKPKTESKERSDSHLSATKLEVLMSGDCSRPNLKPKLPKQDTAIYQEKLLTFPSYTDVKEYSNSAHQSAFIKERSQFNAASFPLNASHSVTSKTGADSPQLPHLSMLLGSLSSTSISNNGSEIVSNCNNGIASTAATLAPTSSRTTDSNPSEVPNQIRSTMSSPDIISAKRNDPAPLSFHMASINDMLETRDRAISNVKTETTPPHFIPFLQSSKAPCISKANSQSISNSVSSSDVSGRKFENHPA 487
53 -13.700[D] COG5279 Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain  ali follow..  19.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GW---------QTKGDLGFLEGDIMEVWGKLLRNKKCSG----------F-----------------------------------HNFVILLEERLNSSTENGRQPSKIVESFEKSNKVVIPPVPSRYSDERPRPKKKLSSSMPNSPKKPVDSLTKARKAKSKEMVNEKNIYNTQSSRHHNNSAPNLPLASHSKPQVRNFEESMNNPLPPLPPLPDLDNMRKTDKRAPKKSYSANDLHMARSSREYNYYKDNQKFYDGFIPEKRYSLEEDSISSGLFSNSQYLNDSACSSENSFALMSDFSATSAGSFARHKYAQSFSDSLQRSQNANGCSTKINDSQEFGDSNASSRNGKMGDILRKIIIPKRNTNIYSSSVSSPKSPKAYPKLPDIQ............. 365
54 -13.700[K] KOG0323 TFIIF-interacting CTD phosphatases, including NLI-interacting factor  ali follow..  248.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EIRDTSVLVKLRPAWEELRSYLTAKTR--KRFEVYVCT---MAERDYALEMWRLLDPEAHLISLKELRDR-KKSLLSVFNGGICHPKMA-----VIDDRMK--YAPQAEACALVVPHLCVARNVACNVRGYFFKEFDESLMSSISLVYYEDDVENLPPSPDVSNYVVIEDPGFASNGNINAPPINEGMCGGEVERRLNQAAAADHSTLPATSNAEQKPETPKPQIAVIPNNASTATAAALLPSHKPSLLGAPRRDGFTFSDGGRPLMMRPGVDIRNQNFNQPPILAKIPMQPPSSSMHSPGGVDDENRPSFPGRPSGLYPSQFPHGTPGSAPVGPFAHPSHLRSEEVAMDDDLKRQNPSRQTTEGGISQNHLVSNGREHHTDGGKSNGGQSHLFVSA......... 661
55 -13.600[D] COG5072 Serine/threonine kinase of the haspin family  ali follow..  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LLHFDIVIQLLSSHTLKSHQVEPPMDFETSFEEALEVSDNDDDCDTDLTADTADELESSAILKMRESDASLNVTTGNNTSRKTTSNSKKRWSLLSNHSAVSSSKSKKRWSVLSSSFTSESHKDRESRNVLQQKRKSLQSYSSLDTVASNSSISASSSLKRSSTGLSLRQLFTKIGINDDISQPGIGIPQGKENLPPTMGKKNSSIASTSSENRLRTPLKPLVNHSKRPTSQPQQQQPLYNASLSSRRSSISSTVSSSSSSKWRFWKRNKNQTPALLQPDHHSLKTFPAVNRRDSMTPVEPRNMVKHKTSFSDFHKT........ 325
56 -13.500[R] KOG4299 PHD Zn-finger protein  ali follow..  2.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DAKPWNHTSEAFQASILEDLKIIQKAGAERNAKSSHGSINSRSASPNKATSRRNRAQNGNSNGRASVDNSDDGSKDDLDYSPSVKRKHVNGEGAEKGDHDTSNNGPSITKLRRKVRRTYDTKDGFVAWNTLDDDFRPIVPDQERSRKINPQKGNNNNLLKENKSLKTTAKDLSDISSSSMKKANNSSKPLFSGKLTFKANIPVPTSEVVTENNVTRNVTVYSNQKHLGNESENFNDMEGRAEDISSNELLPTPEEYPYRYNNPNS-DPP. 293
57 -13.400[K] KOG2150 CCR4-NOT transcriptional regulation complex, NOT5 subunit  ali follow..  72..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KDKDSLLDYRRSVEIAMEKYKAVEKASKEKAY---SNISLKKSETLDPQERERRDEYLSQM--DELERQYDSLQVEIDKLLLLNKKKKTSSTTNDEKKEQ-YKRFQARYRWHQQQMEL-------ALRLLANEELDPQDVKNVQDDINYFVESNQDPDFVEDETIYDGLNLQSNEAIAHEVAQYFASQNAEDNNTSDANESLQDISKLSKKEQRKLEREAKKAAKLAAKNATGAAIPVAGPSSTPSPVIPVADASKETERSPSSSPIHNATKPEEAVKTSIKSPRSSADNLLPSLQKSPSSATPETPTNVHTHIHQTPNGITGATTLKPATLPAKPAGELKWAVAASQAVEKDRKVTSASSTISNTSTKTPTTAAATTTSSNANSRIGSALNTPKLSTSSLSLQPDNTGASSSAATAAAVLAAGAAAVHQNNQAFYRNMSSSHHPLVSLATNPKSE. 517
58 -13.400[U] COG3846 Type IV secretory pathway, TrbL components  ali follow..  276..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ASIVGGGGATAGIGNFGAGAAIAAAATGAAVAATAGSALAAGLSSAGGGVSALKAAFQSAQQNMASGGGSGSGSGSGGNSAGVSSGGSSSFMSAMGTTGRFAADMGTSLAKGVGQVAKDKAGSVIASAKERVADTTGGKVASAIRNSMDAASGQNDFKGDSLAGAAQRGSETAMNDEVAAFVNKGKQHE 464
59 -13.300[S] KOG4615 Uncharacterized conserved protein  ali follow..  183............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RRSPTLSPNNRRSMRRSGNVPGSDKLRRHAIRRRSRSCGRQLLPEFEETVNLTRSISSPVNFLPEISSTPCTEKQKEEVAKNTTRVETDKPAEKPMELSQEPEPENPLQTKVTSPARNPILAAEIEQICKERQSSFHKNVLQLDYSGRAPYSRPPTPSSPSVAGLRRTYTMEKGPAPGQLLLSPSHRYDTPSKMPVVKAKRFNQELMVPDTPERQSHDPAWQSEPQPEFVVPETQPQDLGELVQTLSRSAISPIVVINTSNSNRSVRRDAVAMKSVPTSPVTALSSPPIAPSPRRSAAASPQK 485
60 -13.300[R] KOG4264 Nucleo-cytoplasmic protein MLN51  ali follow..  165..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KGPKHLDDDEDRKNPAYIPRKGLFFEHDLRGQTQEEEV---RWDKFREDEQ-------PKSRQELIALYGYDIRSAH------------RDPNWNGERLNKS-----FINRNAAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQ 615
61 -13.300[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  99.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NLTW-------------------------W---------TTDQDIANSLRDIGVSDLQEV-------KFFENRANGQSKGFSSESSLRAVLDQLPK-----------------KEMHGQAPVVTYPSKQALTQFESLQKTRPVPPPQQNGPPRGPAPPSMGGGPMPTGHPGGPQGGGPPGHPPRGMNSIMQPGQYRPQHMSQVPQVGGPNSGPPRMQPPMHPQGGLMGNQQPPPRYPSAQGQWPGQRPGGPRPGPPNGPPQRPMFQGGPMGMPVRGPAGPDWRRPPMHGGFPPQGPPRGLPPAPGPGGPHGAPAPHVNPAFFNQPGGPAQHPGMGGPPHGAPGPQPGMNMPPQQGMNMTPQHGPPPQFAQHGPRGPWPPPQGKPPGPFPDPQQMGPQLTEVEFE 449
62 -13.300[K] KOG4797 Transcriptional regulator  ali follow..  4.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MPAKKKSCFQITSVTTAQVATSITEDTESLD----------------DPDESRTE--------------------------------------------------------VSSEIFSRATDYGPEEVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQ 382
63 -13.300[TZ] KOG2546 Abl interactor ABI-1, contains SH3 domain  ali follow..  3..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TETPMASENIMDELASLIRT--EIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSL-ASVAYQINTLAYSQLLELQAQQ--LGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINPEKPIKYVRKPIDYSMLDEIGHGINSAQHSQVRQKHRGSSHGSVQSLLPPSVGPPPTTKPPTPPQMSRAGNTGTLGKSVSNTGTLGKSSREYRTPPVVNPPQVPSHYAPNYPIGHPKRMSTASSTMTTTTTGGGAAGNERAAGYSALPMPPSQQIATHVNLPSAGMMQSLPPPPPTTYDDRSSMPPAPPSPLTVSQHEMTEQSHIGMHTLGRNINRNHFSLNFARPGSQSPPLPPPPPPEDEHQDFGRPRTSTGPQLAPIVPEDQNL 408
64 -13.200[S] KOG2129 Uncharacterized conserved protein H4  ali follow..  91......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NRDLRKASVTIQARAEQEEEFISNTLFKKIQAL----QKEKETLAV--NYEKEEEFLTN--LSRKLMQLQHEKGE--LEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAETRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSGSHLAAYSFATFGAHLLPALMHELSLNFKLGLIQWSRLLNAKGS... 499
65 -13.200[K] KOG2181 LIM domain binding protein LDB1/NLI/CLIM  ali follow..  100.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EFRIHDMNRRLYIFSSTGVSENDQQQWWDAFSHERYIINRQFIPKFFRSIFDSGMRELTEGKLYVEFLKRSNEFVYNQNTADYRLMTMLKILDPMQSIMSSAKSAPAITPREVMKRTLFQHHQVRQQNMRQQQLNQQMMIPAPEPEKPKPARKRQRKPAANPRGSKKATAAAAAAAAAATNGVPPTVPTASPANNQQFPPNPMTSQFQQMSYPDVMVVGEPSMMGSEFGENDERTISRVENSQYDPNAMQMQSLGQGPNSSMNINGRNMMNQHHPGMQPPPGQQHMPPHSMGSQMPTSMHNPMHMPPGSMQGHGGMPPMPSTMANQMPPPNLPPNQMPNSRMPPMQGQMPPSGMPGQMSNPNMMGSGMPPMSMSSQMPGSMSNPMPNQMPGGMQMNQMPPPN 607
66 -12.900[K] KOG3915 Transcription regulator dachshund, contains SKI/SNO domain  ali follow..  2..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTPQN. 185
67 -12.900[K] KOG2393 Transcription initiation factor IIF, large subunit (RAP74)  ali follow..  262.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DDDDEEGPRGGDLDMDDDDIEKGDDWEHEEIFTDDDEAVGNDPEEREDLLAPEIPAPPEIKQDEDDEENEEEEGGLSKSGKELKKLLGKANGLDESDEDDDDDSDDEEETNYGTVTNSKQKEAAKEEPVDNAPAKPAPSGPPRGTPPAKPSKGKRKLNDGDSKKPSSSVQKKVKTENDPKSSLKEERANTVSKSNTPTKAVKAEPASAPASSSSAATGPVTEDEIRAVLMEKKQVTTQDLVSRFKARLKTKEDKNAFANILRKISKIQKNAGSQNFVVLREKCQPKPGKRESRVNKLNIRSNLQPRKM.. 569
68 -12.900[A] KOG2669 Regulator of nuclear mRNA  ali follow..  15.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AKLNSTQQSIQSQWCIVHRSE-----------AELVVTTWEKQFHSGQKVPLLYLANDILQFVQEFWKVLPGDYGKGVVSRLVNIWEERRVFGSRSKSLKDVMLSEEAPPPLDVSKKRFRGSKSAKRDSKSTKTKLSSGGVSEKIVSAFNLVRAENSNEETEMNKCKSAVRRIRKMEKDVEDACSTAKDPRKESLAKELEEEENILRQSVEKLKSVEESRTSLVNHLREALREQESELENLQSQIQVAQEQTEEAQNMQKRLNNETPVNNNNGTSGQSAKITPASIAAMAEMLTSSTNSSMIMHSVLSSFAAEATQTSGLTKSNTSDTNAFVVPPNPQQYHIIPNPAASQQF--PYGFGNIPLMPPGALPPPPPGTLPPHMMNNNNQPNAAQQQAQQGQSFHPPGMMYFGPPHH 438
69 -12.700[R] KOG3107 Predicted haloacid dehalogenase-like hydrolase (eyes absent)  ali follow..  6..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPA 262
70 -12.600[S] KOG3819 Uncharacterized conserved proteins (Hepatitis delta antigen-interacting protein A)  ali follow..  10  68.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LDHSNLIREVNRRLDINQKLQEDNQELRDFLDDDRQKKRVSREWQRL---------------------RYTAGVMHKEV-ALYLQKLKDLKQEEVVKENELKELCVLLDE---EKGAGCAGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGS-PEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSP-DHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIG 477
71 -12.600[Z] KOG3655 Drebrins and related actin binding proteins  ali follow..  21...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DDKSDTNWSLFGYEGQTNELKVVATGDDELNEDLNSGKIMYAFVRIEDPKTGLNKYL-------APVLRKGTCANHIRDVSNL--IDLDRLLKKLSTVSSAYSFKEPRGAMEEQKAPVGTNYTRVIPTKELNASVMQDFWKKEEAEEKLRQEAEKESKRLELQKLEQEQRSREEKEHKEREKLVISTTKLQPAHVPIKTSPQPLSPEKTAPGFANNLTDAERMRQARNQEARELIGSRVGAAKAMFTKHTSEGQLQSKLNTQPPAKPARNSIAQRINVFNQNQPQDAPVPSPPRAASPAKPLPVEAPEPVVPAPAIAPAAPVAAEVVSTIAEVEESQPVDDLPLAHESEQFSTIKRSPHSKSNSLQSQSPDETTSSNETDTAVSQEQEEEVRTKVSVTVQQSQSVKSS 445
72 -12.600[S] KOG4610 Uncharacterized conserved protein  ali follow..  165.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RWLLPKTRDQLSQLADIIEFFDSYLGIWSWSLMQFTIV-GIDVWGIVLNVILQDAPFLT---------FRLLIIFQYKIINYMNVFFTCKNSLVIILQLYRLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS........................................................................................ 523
73 -12.400[T] KOG4590 Signal transduction protein Enabled, contains WH1 domain  ali follow..  10  19....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DDTSKKWV--QGFSRINIYHN--TASNTFRVV-QQVVINYSIVKGLKYNQATPTF-QVYGLNFASKEEATTF--------------SNAMLFALNIMNSQEGGPSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDA............................................. 379
74 -12.400[K] KOG3119 Basic region leucine zipper transcription factor  ali follow..  10  234..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PDNKKDESYWDRRRRN--------NEAAKR---------REKRRYNDMVLEQRVIELTKENHV-LKAQ---------LDAIRKFNISGENLVSV-----KILASLPTSEQVLSNTKRAKMSGSGGSSSGSSPSGSGSGEGSPQGGHNGYPVGPPLSPLIYGPNGNARPEATVKSVHHIHHAGVAPPPTHLQQLVVPQSQTQHLYQPQPQQHQPHQQQQISQPPQQQQQQQEPSPSAGSSSPVISDPHNRPPSTTIANLQVQLQQALNRNVRPEDLDSLRKVVAAGALYNAAAVVGAPPPPPSAGLYVPAPSAYKDHLEAAAAWSHNVEAAVSSSAVDAVSSSSVSGSAASVLNLSRRACSPSYEHMLSSTTSSTLSSASSSGAVSGDDEQEHEPAHMAPLQLQRSSPQQ 613
75 -12.400[B] KOG4140 Nuclear protein Ataxin-7  ali follow..  587.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQPKAP. 892

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.