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Query: [E] KOG2380 Prephenate dehydrogenase (NADP+), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAETLITKPPLSLSFTSLSSMLPSLSLSTANRHLSVTDTIPLPNSNSNATPPLRIAIIGFGNYGQFLAETLISQGHILFAHSRSDHSSAARRLGVSYFTDLHDLCERHPDVVLLCTSILSIENILKTLPFQRLRRNTLFVDVLSVKEFAKTLLLQYLPEDFDILCTHPMFGPQSVSSNHGWRGLRFVYDKVRIGEERLRVSRCESFLEIFVREGCEMVEMSVTDHDKFAAESQFITHTLGRLLGMLKLISTPINTKGYEALLDLAENICGDSFDLYYGLFVYNNNSLEVLERIDLAFEALRKELFSRLHGVVRKQSFEGEAKKVHVFPNCGENDASLDMMRSEDVVVKYEYNSQVSGSVNDGSRLKIGIVGFGNFGQFLGKTMVKQGHTVLAYSRSDYTDEAAKLGVSYFSDLDDLFEEHPEVIILCTSILSTEKVLESLPFQRLKRSTLFVDVLSVKEFPRNLFLQTLPQDFDILCTHPMFGPESGKNGWNNLAFVFDKVRIGMDDRRKSRCNSFLDIFAREGCRMVEMSCAEHDWHAAGSQFITHTVGRLLEKLSLESTPIDTKGYETLLKLVENTAGDSFDLYYGLFLYNPNAMEQLERFHVAFESLKTQLFGRLHSQHSHELAKSSSPKTTKLLTSLast
1 -143.000[E] KOG2380 Prephenate dehydrogenase (NADP+)  ali  100  1MAETLITKPPLSLSFTSLSSMLPSLSLSTANRHLSVTDTIPLPNSNSNATPPLRIAIIGFGNYGQFLAETLISQGHILFAHSRSDHSSAARRLGVSYFTDLHDLCERHPDVVLLCTSILSIENILKTLPFQRLRRNTLFVDVLSVKEFAKTLLLQYLPEDFDILCTHPMFGPQSVSSNHGWRGLRFVYDKVRIGEERLRVSRCESFLEIFVREGCEMVEMSVTDHDKFAAESQFITHTLGRLLGMLKLISTPINTKGYEALLDLAENICGDSFDLYYGLFVYNNNSLEVLERIDLAFEALRKELFSRLHGVVRKQSFEGEAKKVHVFPNCGENDASLDMMRSEDVVVKYEYNSQVSGSVNDGSRLKIGIVGFGNFGQFLGKTMVKQGHTVLAYSRSDYTDEAAKLGVSYFSDLDDLFEEHPEVIILCTSILSTEKVLESLPFQRLKRSTLFVDVLSVKEFPRNLFLQTLPQDFDILCTHPMFGPESGKNGWNNLAFVFDKVRIGMDDRRKSRCNSFLDIFAREGCRMVEMSCAEHDWHAAGSQFITHTVGRLLEKLSLESTPIDTKGYETLLKLVENTAGDSFDLYYGLFLYNPNAMEQLERFHVAFESLKTQLFGRLHSQHSHELAKSSSPKTTKLLTS 640
2 -57.700[E] COG0287 Prephenate dehydrogenase  ali follow..  16  1.....................................................................................................................................................................................................................................................................................................................................................................MMGDIMFERIALIGIGLIGSSIARDVRELGRHVVISTRSEDTKRAEELALGTDYTVSAEAVKDADLVIVSVPVGASESVAQQIA-PYLKPSAIVTDVGSTKASVIAQMAPHMPENVHFIPGHPLAGTEKSGPDAGFAGLFRERWCIFTPGTDAAALERLKDFWRALGSRVDEMDAEHHDKVLAIVSHLPHIIAYNIVGTADDTESEVIKYSASGFRDFTRLAASDPTMWRDVCLHNKDILEMLARFSEDLASLQRAIRWGEGDKLFELFSRTRSIRRSIIEAG 293
3 -35.200[R] COG4007 Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase  ali follow..  11  2..................................................STMKVAVYGAGNQGSRMAIEFAEAGHDVVLAEPADMLDDAHWKVVEDVTDNDAEAASEAEIAVLFTPFGKKTFEIAKNITNHLPEGAVIANTCTVSPVVLYYVLERERKDLGIASMHPAAVPGTPQ-----HGHYVIGGHSSSELDIATDEQISRCVELAESCGKVAYVVPADVSSAVADMGSLVTAVTLSGVLDY----YYVGTQIIRAPKEMVEKQILMTLQTIASLVETSGNGMLKAMNPELLVRSAKSMHLLEEQEELDAALNTLSDLDDEVNKWIEKGEIRHTDLVAAQALAKEIKN----------------LMGGKAAEGTIRRCMRK............................................................................................................................................................................................................................................................... 341
4 -32.600[C] COG4074 H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase  ali follow..  1MIDMKLAILGAGCYRTHAASGITNFSRAC---EVAEMVGKPEIAMTHSTITMGAELKELAGVDEVVVADPVFDNQFTVIDDFAYEDVTHPEDLGFEITTDDRE-AVADADFIMTWFPKGDMQPGIIDKFIDDIKPGAIVTHACTIPTTKFYKIFEEKPETLNVTSYHPGAVPEMKGQV-------------YIAEGYASEEAINTLFELGQKARGNAYRLPAELLGPVCDMCSALTAITYAGILSYRDSVTGFAQMMAKESLEQITALMEKV-GIDKMEEHLDPGA------LLGTADSMNFGASADILPTVFEILEKRKK............................................................................................................................................................................................................................................................................................................................... 347
5 -19.000[C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific 2-hydroxy acid dehydrogenase superfamily)  ali follow..  106....VVKNAVADLAIGLMIAAGRHFHAGRTEIERSQWKIEQINWMMGQEIRDSVIGFFGFGGISQAIAKRLQCWDVAKIIYHTRTRKENDGDFKAEHVS---EQLLQESDFLVVAAPLNETREKFNGKAFNLMKRSSVFVNVARTTPEPLPANSPLLNVPNCEGLKM--STTKPFKVLIAHT-----------------DVPPEGIEILKEQ--LQVINEPPKNRPEILEKIRGAHAVIWGGRDILNAEILDAAGPQLKAVSTMSSGINNVDVPELKKIPLGSDLTVGLLIAAARRFQEGRRKIDSDKWDKDHLNWMLGQDIRDS----------------------------------------TVGFYGFGGIGQAVAKRLMGFDIKRMLYTTRNRVSQDIEERFNAKKVDFETLLAESDFLIIASPLTETLGLFNATVFNKMKETAVLVNVGRGKIVNQDDLYEALKSNLDVMDPEPL----------SNDKLLTLDNVVVTPHVGYATRRTRVDAANLASRNVL................................................................................................................ 585
6 -18.700[R] COG2085 Predicted dinucleotide-binding enzymes  ali follow..  10  2................................................SHTKPSIAILGAGRVGSSLARSAVAAGYEVKVAGSGAVDKIAEILMPGAVPSTADQAVKDADIVFLAVPLHKFRSVNPAT------EGKIVIDTMN-PRSTSEIIAEFFAGSTMVKSFNHIGYHEIEQDAGTGRAIAYA---------TDDVDAGAQVAQLIKSFGFVPLNIGALENGRILEPGQEA..................................................................................................................................................................................................................................................................................................................................................................................................................... 191
7 -15.900[S] COG5495 Uncharacterized conserved protein  ali follow..  7.......................................................................................................................................................................................................................................................................................................................................................................LRSARLNIAILSTGRVGVALERADQV--VACSAVSHASRQWVQFRLPETSVASPPE-VASSAELLLLAVPDCEFAGLMSGVATSVPRPGTIVAHTSWANG--VGILAQLGKDGCIPLAIHPAMMFSGSDEDLSQCQL--RDTYFGITKTDDVGYAIAQSLVLEMGGEPFCVVEYAHSVSPHVGNHIVTVLADA-LEVRRSALRGSELLGLGVPPACRGEVVDDQLDVIVERIVGSLARAACENTLQR-AGLTKLVARGDLDALAGHLVALMRIGPEL.... 282
8 -15.900[EH] COG0059 Ketol-acid reductoisomerase  ali follow..  10  36..................................................KGKKIVIVGCGAQGLNQGLNMRDSGLDISYALRPEAIAEKRASFQRATENTYEELIPTADLVVNLTPDKQHSKVVADVM-PLMKKDSAFGYSHGFN---IVEVGEEIRKDITVVMVAP--CPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHVLESSFVAEVKSCGMLQAGSIVCYDKLVADGKDPAYAGKLIQYGWETITEALKQGGITLMMD-RLSNSAKLRAFELAEQIKESLGFLYYK-----HMDDIISGHFSATMMADWANGDKDLFAWREATGKTAFENAPKYDGKISEQEYFDNGVLM-IAMVKAGVELAMVASGIY-SLHELPLIANTIARKRLYEMNVVISDTAEYGNYL------ILAKEIIPNLQKGDLGEPTPAVEVDAIRNHPVELIGQELRGYMTDMKRIAVAG............................................................................................................................................................. 492
9 -15.000[I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases  ali follow..  16  1...........................................................................................................................................................................................................................................................................................................................................................................METIGFIGLGIMGAPMAGHLLDAGYKVIASDHRSKPLADLVAKGLKTVSGHAAVAKAADIIITMVP-PQVADVLDNGVASGLTRGKLVIDMSSISPIETKVFAGKINEGCDYLDA-PVSGGEVGAKAASLTIMV---------GGEEKAFERAKPVFEKMGKNITLVGPNGVGQTTKVANQI--VVALTIEAVA................................................................................... 186
10 -14.000[G] COG1023 Predicted 6-phosphogluconate dehydrogenase  ali follow..  11  1............................................................................................................................................................................................................................................................................................................................................................................MQLGMIGLGRMGANIVRRLAKGGHDCVVYDHDPDAVKAMAGE-VASLRELSQRLSAPRVVWVMVPAGNITTAVIEELANTLEAGDIVIDGGNTYRDDLRHEKLLFKKGIHLLDC-GTSGGVWGRE--RGYCLMIG---------DGDAFARAEPIFATVAPGV---TPGRDGEVAPSEQGYLHCSGHFVKMVHNGIEYGMMASLAEGLNILRN-ADVGTRVQHGDAETAPLPNPECYQYDFDIPEVAEVWRRGS...................... 253
11 -12.500[E] COG0345 Pyrroline-5-carboxylate reductase  ali follow..  11  2..................................................ENQKIGFIGAGKMGSALMQGTIKAGNIGASDVYEPFLKDLQAKLGIRVSTDNAVIVRESDILILAVKPQTLSSVLSNLKNEITSEKLVISIAAGVP---LSTYEDALLEGTRVVRVMPTVSEAASGI---------------APGKNATPEDLKAALEIFSAVG-TAVQVPESLMDAVTGLSGSGPAFIFPVIEAMAKSALTLAAQTVLGAAKMALETGMHPGELKDMVTSPAGTTIQGIHSLEE--AGIRAAFMNAVIRASERSKELGKK............................................................................................................................................................................................................................................................................................................................... 270
12 -11.800[M] COG1004 Predicted UDP-glucose 6-dehydrogenase  ali follow..  10  1....................................................MKVTVFGIGYVGLVQATVLAEVGHDVLCIDIDPLVKENYEAGRLQFSTDAQAGVAHGVIQFIAVGLKYVLDVASTIG-TYMDSPKVIIDKSTVPVGTADKVHQVIQAILE-VVSNPEFLKEGAAVADCKRPERIVI---IDTDDSGALELISELYEPFNRNHDRMLVMDIRSAELTISFMNEIANIAERLVRQGIGSDSRIGYHFIYSGCGYGGSCFPKDIQALIRTAEDKGYKPQLLQAVEQINNQQKYKLTEFIKSHFNSQLAG----------------------------------------------KTFAVWGLAFKPNTVMESLWEAGATIQAYDMDETQRIYGARDDLRLMGTKESALQGADALIICTEWQSFRAPDFDMIKSRLK-HPVIFDGRNL....................................................................................................................................................................................... 423
13 -11.800[E] KOG3124 Pyrroline-5-carboxylate reductase  ali follow..  12  1....................................................MSVGFIGAGQLAYALARGFTAAGHKIIASSPEMNLSALRKMGVNLTRSNKE-TVKHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMTVVQEGATVY---------------ATGTHALVEDGQLLEQLMSSVG-FCTEVEEDLIDAVTGLSGSGPAYAFMALDALADGGVKMGLP--RLAIQLGAQALLGAAKM---LLDSEQHPCQLKDNVCSTIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKIS................................................................................................................................................................................................................................................................................................................ 278
14 -11.600[G] KOG2653 6-phosphogluconate dehydrogenase  ali follow..  13  2...........................................................................................................................................................................................................................................................................................................................................................................SADFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDAKGKSIIGATSIEDFISKLKRPRKVMLLVKAGAPVDALINVPLLEKGDIIIDGGNSHFPDSNRRYEELKKGILFVGS-GVSGGEEGAR--YGPSLMPG---------SEEAWPHIKNIFQSISAKSDGEPCCEW----HYVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAK........................................................... 220
15 -11.500[M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase  ali follow..  10  12................................................KSRQALIGIVGLGYVGLPLMLRYNAIGFDVLGIDIDDVKVDKLNAGQCYIEHTDFSRVSECDALILCVPMSFVINTTDALK-PYLRVGQVVSLESTTYPGTTEEELLPRVQEGGLLVYSPIGGHTPQCLEVGIALYEQAIDRVVPVSSTKAAEMTKLLENIHRAVNIGLVNEMKIVADRMGIDIFEVVDAAA---------TKPFGFTPYYPGPGLGGHCIPIDPFYLTWKAREYGLHTRFIELSGEVNQAMPEYVLGKLMDGLNE-------------------------------------------AGRALKGSRVLVLGIAYKKNVIMELIEAKGGMVAYSDPPVFPKMREHHFELSSEPLTAENLARFDAVVLATDHDKFDYE------LIKAEAKLVVDSRGK....................................................................................................................................................................................... 425
16 -11.300[G] COG0362 6-phosphogluconate dehydrogenase  ali follow..  13  2.........................................................................................................................................................................................................................................................................................................................................................................SVKGDIGVIGLAVMGQNLILNMNDHGFKVVAYNRTTSKVDAKGTNIIGAYSLEDLAAKLEKPRKVMLMVRAGDVVDQFIELPHLEEGDIIIDGGNSNYPDTNRRVKALEKGIRFIGS-GVSGGEEGAR--HGPSIMPG---------NQEAWQYVKPIFQAISAKTEQGEP-------HFVKMVHNGIEYGDMQLICEAYQFLKEGLGLSYEEMQAIFAE........................................................... 223
17 -11.000[G] KOG0747 Putative NAD+-dependent epimerases  ali follow..  10  1..............................................MASYTPKNILITGAGFIASHVANRLIRSDYKIVVLDKLDYCSNLKNLNPSKHSPNFKFVIASADLVNHLLITEGIDTIMHFAAQTHVSFEFTKNNIYGTHVLLEACKVTGQIRRFIHVSTDEVYGETDEDALVGNHEASQLLPTNPYSATKAGAEML--VMAYGRSYGLPVITTGPNQFPEKLSNVRSYLYCEDVAEAFEVVLHKGEVGHVYNDVAKDICKLFNMDPEANIKFVDNRPFNDQRYFLDDQKLKKLGWSERTTWEEGLKKTMDWYTQNPEWWGDDGSEDNSLAATLSEKPSQTHMVVPSQRSNGTPQKPSLKFLIYGTGWIGGLLGKICDKQGIAYEYGKGRLEDRSSLL---------QDIQSVKPTHVFNSAGVTGRPNVDWCESHKTETIRANVAGTLTLADVCREHGLLMM-----NFATGCIFEYDDKHPEGSGIGFKEEDTPNFTGSKTKAMVEELLKEYDNV----LRVRMPISSDLNNPRNFITKISRYNKVVNIPNSMTVLDELLPISIEMAKRNLKGIWNFTNPGVVSHNEILEMYRDYINPEFKWANFTLEEDASKLKKEFPELLSIKESL.... 658
18 -10.800[I] KOG2304 3-hydroxyacyl-CoA dehydrogenase  ali follow..  3................................SSTCTAAVRGLSTTAQLSKINNVTIIGAGLMGSGIAQVSANAKLNVTVVDSNQTALVSSVLDRIKMSTNVSDSVKDADLVIEAIVIDIKRKLFAEVEVAAKPTTLITTNTSSLR---LADIGLNLKDKSRFGGLH-FFNP-----------VPMMKLLEVVRHTETSDATFNQLVDYGKTVGKTTVACK................................................................................................................................................................................................................................................................................................................................................................................................................................... 207
19 -10.700[K] KOG0067 Transcription factor CtBP  ali follow..  11  48..............................................................................................................................................................................................................MPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKA-----LRVIVRIGSGYDNV--DIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREG--------------------VQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQD-LLYQSDCVSLHCNLNHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGLDVHESEPFSFAQG--------PLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRA.............................................................................................................. 344
20 -10.500[R] COG1712 Predicted dinucleotide-utilizing enzyme  ali follow..  11  2....................................................LKIGIVGCGFIGGQICRAIDGG--ALCDSSESKALELAASLKTCPSYMKIEELIRGVDLIIESAS----QNAVRFIVPQALKAGCMILSVGALADEELRDTLFGLAKEHNYFPSGAVVGIDGLNSASAAGISSVTLSTRKPPAGLMGAPYVVEHGIELEKLEKKTVLFEGPASEAVKAFPANVNVAATISLAGIGFERTRIADPSLFRNVHEI-IVEGEFGKFSTRVSPENPKTSYLA-SAVSTLKKILNPVQ............................................................................................................................................................................................................................................................................................................................................... 268
21 -10.400[C] COG0240 Glycerol-3-phosphate dehydrogenase  ali follow..  11  2...........................................................................................................................................................................................................................................................................................................................................................................KQHIGYLGMGIWGFCLASLLANKGYPVVAWSRNPDLIKQLQEE-LSFTTDMKEAIHNAFMIVEGVTSAGIRPVAEQLKQITDLSVPFVITSKGIEQNTGLLLSEIMLEVLGDSVTPYLSGPSIAKEVLNGS-----PCSVVVSAYDSQTLKQIHEAFSLPTFRVYPNTDIKGAALGGALKNV--AIACGIAEGLSFGNNAKAGLVTRGLHEMRKLADCKPETLNGLAGLGDLCVTCFSESSRNLRFGHLLAQGLTFEQAKAKIGMVVE......... 282
22 -10.000[I] COG1250 3-hydroxyacyl-CoA dehydrogenase  ali follow..  10  3....................................................KTVGIIGAGQMGCGIAHVSAAAGYKVQLYDIAASDEDRKRALSLIKGSGDINDLAQADLVIEAVTETVKRKIYGQVCPVMRPDAILATNTSSLS---ITRLASATDRPERFMGIH-FMNP-----------VPVMKLVELVRGIATEEETFKAAKEFVAHLDKTVTVAEDFPAFIVNRILLPMINEAIYTLYEGVGTVDAIDT................................................................................................................................................................................................................................................................................................................................................................................................. 215
23 -10.000[S] COG4408 Uncharacterized protein conserved in bacteria  ali follow..  10  2....................................................SKLLMIGTGPVAIQLANICYLKSDEIDMVGRASTSEKSKRFEINRLYKDVKNVKGEYETVVMACTADAYYDTLQQLSLETLQSVKHVILISP--QMIVEQFMSKFSQDIEVISFSTYLGDTRIVDKEAPNHVLTTGVKLYMGSTHSNSTMCQRISALAEQLKIQLEVVE----HAETRNSSLYVH-PPLFMNDFSLKAIFEGTDVPVYVYKLFPE----TMTLIREMRLMWKEMMAILQAFRVPSVNLLQFMVKENYPVRPETLDEG................................................................................................................................................................................................................................................................................................................................. 296
24 -9.550[H] COG0499 S-adenosylhomocysteine hydrolase  ali follow..  3......................................................................................................................QVMDFKVADLSLAEAGRHQI--RLAEYEMPGLMQLRKEFADE------QPLKGARIAGSIH--------------------TVQTAVLIETLTALGAEVRWASCNIFSTQDEAAAAIVVGSGTVEEPAGVPVFAWKGESLEEYWWCINQIFSEQAGLVPPAEANDSDEYIAFLGMLREVLAAEPGKWGKIAEAVKGVTEETTTGVHRLYHFAEEGVLPFPAMNVNDAVTKSKFDNKYGTRHSLIDGINVLVCGYGDVGKGCAEAFDGQGARVKVTEADPINALQALMDGYSVVTVDE-AIEDADIVITATG----KDIISFEQMLKMKDHALLGNIGHFDNEIMHSLLHRDDVTRTTIKPQ-----DEFTFSTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFADQTIAQIELFQNEGQYENEVYRLPKVLDEKVARIHVEALGGQ----------LTELTKEQAE-YIGVDVAGPFKPEHYR....................................... 477
25 -9.530[CHR] COG1052 Lactate dehydrogenase and related dehydrogenases  ali follow..  12  147............................................................................................................................................................................................................................................................................................................................................................................SRVGILGTGRIGQAAARLFKGVGAQVVGFDPYPNDAAKEWLTYVSMDE----LLSTSDVISLHMPAKDSHHLINAKTIAQMKDGVYLVNTARGAVIDSQALLDSLDKGLDAYEFEGPYIPKDNGNN-VYARLVAHERIIYTPHIAFYTETAIENMVFNSLDACTTV.............................................................................................................. 319
26 -9.530[I] KOG1206 Peroxisomal multifunctional beta-oxidation protein and related enzymes  ali follow..  10  10.....................................................RVVVIAGGGLGKVYALAYASRGAKVVVNDLGGTLGGSGHNSKAADLVVDEIKKAGGIAVANYDSVENGEKIIETAIKEFGRVDVLINNAGILRDVSFAKMTE------SVVDVH-LTG---------------GYKLSRAAWPYMRSQKFGRIINTASPAGL---NFGQANYSAAKMGLVGLAETLAKEGAKYNINVNSIAPLARSRMTELVLYLTHESTKVSNSIFELAAGFFGQLRWERSSGQIFNPDPKTYTPEAILNKWKEITDYRDKPFNKTQHPYQLSDYNDLITKAKKLPPNEQGSVKIKSLCNKVVVVTGAGGLGKSHAIWFARYGAKVVVNDIKDPFSVVEEI----NKLYGEGTAIPDSH----DVVTEAPLIIQTAISKFQRVDILVNNAGILRDKSFLKMKD------AVLKVH-LFST-------------FSLSKAVWPIFTKQKSGFIINTTSTSGI---NFGQANYAAAKAAILGFSKTIALEGAKRGIIVNVIAPHAETAMTKTI................................................................. 509
27 -9.520[M] COG0773 UDP-N-acetylmuramate-alanine ligase  ali follow..  12  24................................ITPLRIENPPERNIMMKNRVTNIHFVGIGGVGSGIAEVLHNLGFKVSGSDQARNTEHLGSLGIQVYPGHTAEHVNGADVVVTSTAVKKENPEVLEQQIPVIPRALMLAELMRFRDGIA------------IAGTH---GKTTTTS------TASILGAAGLDPTFVIGGKLNAAGTNARLGKGEYIVAEADESDASFLH--------------------------LTPIMSVVTNIDEDHMDTYGH-----EKLHQAFIDFIHRMPFYGKAFLCIDSEHVRAILPKVSKPYATY-GLDDTADIYATDIENVGAQMKFTVHVQMKGHEQGSFEVVLNMPGRHNVLNALAAI--------------------------------------GVALEVGASVEAIQKGLLGFEGVG-RRFQKYGDIKLPNGGTALLVDDY--------GHHP---VEMAATLSAARGAYPEKRLVLA---QPHRYTRTRDLFEDFTKVLNTVDA---EVYAAGEEPIAAADSRALARAIRVLGKLEPIYCENVADLPEMLLNVLQDGDIVLNMGAGSINRVPAALLELSKQI.............................. 506
28 -9.490[H] COG1893 Ketopantoate reductase  ali follow..  10  1.........................................................................................................................................................................................................................................................................................................................................................................MEKPRVAVIGSGSIGLLLYAYLKLANWPALLVTNRPEQADHLNKE-VTATPLSSFSAEEAEVGFITVKSFAVKALLPQLQ-RKKWDGLVFFQNGMTHLEILRQIPA------AICCGIVEIGAKRESDVRVQHT--DGAIWIGDMVGDSKNFDPMWACLHNAGLKAQNWQDKMERKLIAAINPLTGLFRVKNGALIENQLFSLLEHLAYTRAICDKTANNLSSMYMDLTHHRRTEIESITGYLIKEAA-KKGIEIPNTSFVYHAVMGMDEEGRK..... 304
29 -9.040[I] KOG1683 Hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase  ali follow..  2LSRVVHRSSSVFRTNLSFRLFSQSAFAVHSTHRVEKQGDVAVMKIDLPNTTENVLNKALFAEMNETLDRLQSDQSVK----------------AIVVMSGKPNSFVAGADIQMFKAEKTA-----AGVSNLLREGQKQLLTIELSQKPIVAAIMSCMGGGLEILACHYRIAVNDKKTLLGLPEVTLGIMPQRLPKLTTVQNVLDLTLT-----GKRIKANKAMK-DRVIQPLGDGICTSTETTHKYLEEIAVQSARELANGKLKINRDKGFVHNATQAVMTSKFVLDNVI---LKMAKNKLIKLTNGNYPAPLKILDVVRTAYLDPKNGYEAEAKAFGELSQTFQSKAGSTNAKKNKYGKGLPVNEIAVVGAGFMGAGIANVTINKGIRTVLLDANQAGVERGQNHVATVPTIDYSAMKNADVVIEAVDLPLKHKVIRQIE-NVVGPNTIIA--SNTSALPIKDIAAASSRSDKVIGMH-YFSP------VEKMQLLE---IITHDGTSKETLATAAQLGLKQGKLVVVVKDCP-VRCLSPMMS-----IVRLLQEGVEPSELDKLTTKFGFPVGAATLADEAGLDVAEHVARYLGTALGPRVHGGSVDLLSELVRA....................... 616

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 6 1 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Godzik A. Surface map comparison: studying function diversity of homologous proteins. J Mol Biol. 2001 Jun 8;309(3):793-806.