current user: public

If you have questions about the server, please let us know.

Query: [Y] KOG2439 Nuclear architecture related protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490
# Score Template Links and tools%idFirst MSALLSESDLNDFISPALACVKPTQVSGGKKDNVNMNGEYEVSTEPDQLEKVSITLSDCLACSGCITSSEEILLSSQSHSVFLKNWGKLSQQQDKFLVVSVSPQCRLSLAQYYGLTLEAADLCLMNFFQKHFQCKYMVGTEMGRIISISKTVEKIIAHKKQKENTGADRKPLLSAVCPGFLIYTEKTKPQLVPMLLNVKSPQQITGSLIRATFESLAIARESFYHLSLMPCFDKKLEASRPESLDDGIDCVITPREIVTMLQELNLDFKSFLTEDTSLYGRLSPPGWDPRVHWASNLGGTCGGYAYQYVTAVQRLHPGSQMIVLEGRNSDIVEYRLLHDDRIIAAASELSGFRNIQNLVRKLTSGSGSERKRNITALRKRRTGPKANSREMAAATAATADPYHSDYIEVNACPGACMNGGGLLNGEQNSLKRKQLVQTLNKRHGEELAMVDPLTLGPKLEEAAARPLSLEYVFAPVKQAVEKDLVSVGSTWLast
1 -141.000[Y] KOG2439 Nuclear architecture related protein  ali  100  1MSALLSESDLNDFISPALACVKPTQVSGGKKDNVNMNGEYEVSTEPDQLEKVSITLSDCLACSGCITSSEEILLSSQSHSVFLKNWGKLSQQQDKFLVVSVSPQCRLSLAQYYGLTLEAADLCLMNFFQKHFQCKYMVGTEMGRIISISKTVEKIIAHKKQKENTGADRKPLLSAVCPGFLIYTEKTKPQLVPMLLNVKSPQQITGSLIRATFESLAIARESFYHLSLMPCFDKKLEASRPESLDDGIDCVITPREIVTMLQELNLDFKSFLTEDTSLYGRLSPPGWDPRVHWASNLGGTCGGYAYQYVTAVQRLHPGSQMIVLEGRNSDIVEYRLLHDDRIIAAASELSGFRNIQNLVRKLTSGSGSERKRNITALRKRRTGPKANSREMAAATAATADPYHSDYIEVNACPGACMNGGGLLNGEQNSLKRKQLVQTLNKRHGEELAMVDPLTLGPKLEEAAARPLSLEYVFAPVKQAVEKDLVSVGSTW 491
2 -84.200[R] COG4624 Iron only hydrogenase large subunit, C-terminal domain  ali follow..  22  1.........MDALIRPPKDNKKCIKIGSPLA----------------------LSLSDCLACSGCVSADEAGALSEDLSFVL---------DLSPQTSFVLSPQSKINIFNLYGMEYREFEAVLSSFLRSKFNIHRIVDTSYLRSKIYEETYREYMAT-----------NHLIVSACPGVVTYIERTAPYLIGYLSRVKSPQQMAFSLVKGS-----------RTVSVMPCQDKKLENGRDGV---KFDFILTTRGFCKALDSLGFRRPARASGKSLCS-------MEEAETTQWNIGTSSGGYAEFILGKHCVVETREIRNGIKEHLLD--------------------------------------------DGRTISQITGLENSINYFKSSKTK--GPRHKMTEIFLCKNGCIGGPGQERVNDVEMDIREYDRNGREQPRIFYSSPGLEE-------------------KRVFREVKAKRVDLRVDW 365
3 -18.400[C] COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit  ali follow..  12  51..............SKCVKCYICWKFCPEPAIYI------------KEDGFVAIDYDYCKGCGICANECPTKAITMVREEK.......................................................................................................................................................................................................................................................................................................................................................................................................................... 105
4 -18.300[C] COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB  ali follow..  14  115..............NNCIGCTKCIQACPVDAIVG------------ATRAMHTVMSDLCTGCNLCVDPCPTHCISLQPVAETPDSWKWDLNT----IPVRIIPVEHHA............................................................................................................................................................................................................................................................................................................................................................................................... 192
5 -17.900[C] COG1146 Ferredoxin  ali follow..  12  44..............DKCVTCGICFVTCGRRVFDFDKK---------EGKVIVARPYNCMVACQTCMNLCPTGAISFPDASYIKKLVAQNKIVKKAFEIIKPLLA................................................................................................................................................................................................................................................................................................................................................................................................... 124
6 -17.500[C] COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)  ali follow..  11  46YRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETEDGRWYPEF----RINFSRCIFCGLCEEACPTTAIQLTPDFEMGEFKRQDLVYEKHDLLIS--------------------------------------GPGKNPDYNYYRVAGMAIAGKPKGAAQNEAEPINVKSLLP......................................................................................................................................................................................................................................................................................................................... 182
7 -17.500[C] KOG3256 NADH:ubiquinone oxidoreductase, NDUFS8/23 kDa subunit  ali follow..  102FRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEE---RADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFE-FSTETHEELLYNKEKLLCNGDKWESEIASNLQAD....................................................................................................................................................................................................................................................................................................................................................................................... 213
8 -15.200[C] COG1145 Ferredoxin  ali follow..  15  278.SSYLATVDTS----RCIACGICMLRCPMKAIKAKI-----------NREPASVDAEKCLGCGVCVPTCPMEAIELVERDELLE--LPDGMTYVQELLADKGRDPSGLF.............................................................................................................................................................................................................................................................................................................................................................................................. 368
9 -13.500[C] COG0348 Polyferredoxin  ali follow..  13  210IGAKGLFRIKVEHRQQCDNCMDCYNVCPEPQV--------RDPLHAKKSESPLVLSKDCISCGRCIDVCPEKVFIFTTRFNHSVNHSGE.................................................................................................................................................................................................................................................................................................................................................................................................................. 291
10 -13.400[C] COG1140 Nitrate reductase beta subunit  ali follow..  11  182..............RLCEHCLNCVATCPSGAI-----------YKREEDGIVLIDQDKCRGWRMCITGCPYKKIYFNWKSGKSEKCYPRIEAGQPTVCSETCVGRIRYLGDAIERAASTENEKDLYQRQLEVFLDKVIEQAIKDGIPLSVIEAAQQSPVYKMAMEWKLALPLHPETLPM-VWYVPPLSPGILPDVESLRIPVQYLANLL-------TAGDTKPVLRAL-----KRMLAMRHYKRAETVDGKLTEAQAQEMYRYLAI................................................................................................................................................................................................................................. 449
11 -12.600[C] COG1035 Coenzyme F420-reducing hydrogenase, beta subunit  ali follow..  10  3.......PKIAEVIDYCAACGACEAVCPIGAVTVKKAAGIRDPNDLSLYEK-GGGYQVCEGCLTCSRVCPVVDGFIQDELTNVRKFFGARSKDNV------------------GSQDGGVASGILKSLFKQGKIDCAVGITRNEKWVLLTSAEDVERTRGTKAFEKYDRIAVIGVPC-AAHLIRENVNEKIVLIIGESFHHDVMLEKIIPEILKVHSVPIKDVAKFARNPCHCCDYTSVFADISVGSVNSVFIRTEIGEKYFDMVREDMEIMEDPKPG..................................................................................................................................................................................................................... 309
12 -12.600[R] COG2768 Uncharacterized Fe-S center protein  ali follow..  202..............EKCTKCDECVKICPSNAIE-----------------DYQINREKCVKCLGCSEACDYGAVKTFW--VFGRDVSERIVECTKGVFKVQKNFAYLNFLMDITPHCDCHPYSDLP-VVPDLGIMASKDIRASVDLYRQAENLSGALLKDKKFWDWTDVEGMLNYA----LELGTQNY-RLIE-IS....................................................................................................................................................................................................................................................................................................... 363
13 -12.500[C] COG1142 Fe-S-cluster-containing hydrogenase components 2  ali follow..  11  1MNRFVIAD-----STLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEKESAPQL---CHHCEDCAVVCPVNAITRVDGAVQL----NESLCVSCKLCGIACPFGAIEFSGSRPLDIPANANTPKAPPAPPAPARISTLLDWVPGIRAIAVKCDL---------SFDEQGPACVRMCPT-LHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSG.................................................................................................................................................................................................................................................................................. 200
14 -12.000[C] COG1150 Heterodisulfide reductase, subunit C  ali follow..  38.............VQACYQCGTCTGSCPSGRRTSYRTRLIMRKLQLGLVDEV-IKSDECTTCYTCYERCPRGV----KIVDAVKAARNLAAKKGY-----MAKAHRMVAMFVIKTGHAVPINDEIREVRKNIGLDEV.................................................................................................................................................................................................................................................................................................................................................................. 154
15 -11.800[C] COG0437 Fe-S-cluster-containing hydrogenase components 1  ali follow..  10  66...............SCNHCDDCTKVCPSGAM------------HKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNAEKGHMTKCYSRVAEGKQPICVESCPLRALEFGP----------------------------------------IEELRQKHGTLAAVAPLPRAHFTK--PNIVIKPNANSRPTGDTTGYLANPEEV............................................................................................................................................................................................................................................................................................... 205
16 -11.100[C] COG2440 Ferredoxin-like protein  ali follow..  18  33..............HERPSANLLTHICPAKCY------------ELNDKGQVETTSDGCMECGTCRVLCEASGE................................................................................................................................................................................................................................................................................................................................................................................................................................. 82
17 -11.000[C] COG1152 CO dehydrogenase/acetyl-CoA synthase alpha subunit  ali follow..  10  393LKKLPDIDEIIELASECTDCGWCQRVCPN-SLPVMDAVKKAADGDLSKLEEMAI-EELCYTCGRCEQECE-------RNIPIVSMVTKAGERRVKDEKYRIRAGRGPAQDVEIRRVGAPIVLGDIPGVVAFVGCSNYPEGG-----DVALMAKEFLER----------NYIVVTTGCGA---------------MSIGEYRDEDGQTLYEKYGGQFDAKG----LVNMGSCVSKPLEGNFEEIADYILNRVGACGVAWGAYSQKAAAIAT............................................................................................................................................................................................................................. 637
18 -10.800[R] COG3383 Uncharacterized anaerobic dehydrogenase  ali follow..  11  132....YLNDFTHPFYDQCILCGRCVEACQVQVNETLSIDWERSQPRVIWDDDRPANLSSCVSCGLCATVCPCNALMEKSMLGQAGFMTGLDEDMLEPMIDMVKQTVFAVSEMEAAMRETRTKKTKTVCTFCGVGCTFEVWTKDRKILKVEPTGEGPVNKWDFVNSEKRITTPLIHLVATKLREIQAKYGNDSIGFISSSKTTNELMQKLARQVFETNNIDNCS--------CQAPASDGLTRTVGIGADSGTVEDIESAGLVIIVGASPADGHP.......................................................................................................................................................................................................................... 433
19 -10.600[C] COG1141 Ferredoxin  ali follow..  11  43...............................................RQKGVYVDEITCIGCKHCAHVARNTFYIEPDYGRSRVIRQDGDAEEVIQEAIDTCPVDCIHWVDYTELKNLEEDRKFQVIPVVGYPVDHAVATTEKRRRKQKSKNKK................................................................................................................................................................................................................................................................................................................................................. 149
20 -9.440[C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit  ali follow..  10  167.............LYECILCACCSTSCPSQAYRWLIDSRDEATGERLDNLEDPFRLYRCHTIMNCAQACPKG-LNPAKAIAEIKKMMVERR................................................................................................................................................................................................................................................................................................................................................................................................................ 258
21 -9.340[C] KOG3049 Succinate dehydrogenase, Fe-S protein subunit  ali follow..  183.............LYECILCACCSTSCPSQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTRTCPKG-LNPGKAIAEIKKMMATYKEKKASV.......................................................................................................................................................................................................................................................................................................................................................................................................... 280
22 -9.330[C] COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)  ali follow..  134.KRTHRNQDLGPFINRCIACYRCVRYYDYADGTDLGVYGAHDNVYFGRPEDGTL---ESEFSGNLVEICPTGVFTDKTHSERYNRKWDMQFAPS---LRRIENRYNGTVNHRFGYGYVNLKDRPRQPVQRRGDMQGAADIGIGSPRASVESNFALRELVGEENFYTG-KVLREGGIYTPALREIESYDAVLV---EDVTQTGARVALAVRQAVKG------KAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAPVEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGA-----------------KKPLIISGTNAGSLEVIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGR-------ADAVVVLENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNEGRAQRFFQVYDPAYYDMLESW 651

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 5 6 5   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.