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Query: [K] KOG2478 Putative RNA polymerase II regulator, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSDLast
1 -94.800[K] KOG2478 Putative RNA polymerase II regulator  ali  100  1MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
2 -16.200[KB] KOG3265 Histone chaperone involved in gene silencing  ali follow..  6  162.....................................................................................................................................................................................................................................................................................................................................................................RTVFVESNKALHLTSNEDDCSGNYKTCINNSSDSFVENLSRKIETEDLRVTTFPIRWTDEDPVAEPVDEEANKVFDEDDLMPLHDDGQDDDEEEEDDDETGPNTEEVDLNESFNERMANAHDGTEQKNGEESMEHDGASGDVEMGDNQLFVQINTDTKATESMVDPLSDTTKRD 335
3 -16.100[R] KOG2295 C2H2 Zn-finger protein  ali follow..  10  298............................................................................................................................................................................................................................................................................................................................................EKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETE 496
4 -16.100[KB] COG5137 Histone chaperone involved in gene silencing  ali follow..  12  115................................................................................................................................................................................................................................................................................................................................................................................................NNEMEGLNLQEMDDAEIKKVKVDISKVWRSILAEKPRVTRFNIQWDNPDFDDAPPVQPDADEEEEEEEADEMEEEFDEEGEGDEEEEEEDDGDGDGEGDGDGEGENDGKGSEEEEEEEIDIEEEEEESALANASAAEEKPEEKPETS 261
5 -15.900[S] KOG4610 Uncharacterized conserved protein  ali follow..  13  320......................................................................................................................................................................................................................................................................................................................................KNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS. 523
6 -15.500[R] KOG4334 Uncharacterized conserved protein, contains double-stranded RNA-binding motif and WW domain  ali follow..  11  2...........................................................................................................................................................................................................................................................................................................................................................................................EQESGGKKSNEQLLSEREAIMRQLAMLGSGPEDLDVDDEEEDEEEEVEKMEEGVEETMENASVVKETTPVKDENIVEDSNSSEELFPYLDSPPEDKIQEISANDTEIDQIDSPIRFEGVKNPAQKMDVDGEEGTSTDARPVSGSSGSSVGEQ 153
7 -15.000[R] KOG4264 Nucleo-cytoplasmic protein MLN51  ali follow..  9  3......................................................................................................................................................................................................................................................................................................................................................................DRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDED 175
8 -14.900[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  9  515.............................................................................................................................................................................................................................................................................................................................................................EAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDTDAHWIIKQQTTSIPAPPSSQQN 696
9 -14.600[B] KOG2266 Chromatin-associated protein Dek and related proteins, contains SAP DNA binding domain  ali follow..  12  2.....................................................................................................................................................................................................................................................................................................................................................................GEDTKATIEPTANKTTSLEKPSEAMAGKENAGGKETQELAKDEDMAEPDNMEIDAQIKKDDEKAETEDKESEVKKNEDNAETQKMEEKVEVTKDEGQAEATNMDEDADGKKEQTDDGVSVEDTVMKENVESKDNNYAKDDEKETKETDITEADHKKAGKEDIQHEADKANGTKD 175
10 -14.200[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  12  283............................................................................................................................................................................................................................................................................................................................................SRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMD 481
11 -14.200[K] KOG2473 RNA polymerase III transcription factor (TF)IIIC subunit  ali follow..  9  403....................................................................................................................................................................................................................................................................................................................................................................................................PEPGFEDVFKSIQEEFERSEKTRIQKDALQPSQRNHQETTKDMKKCKNTNKEKDDDVNADEDSEDLDDEYEEAANDDDISISSHGYGDMENNSRTYLQGLFNRFPSSASALYGSANDDNDSDGEYPIYEQESNALDDDEEDDE 545
12 -14.000[K] KOG2393 Transcription initiation factor IIF, large subunit (RAP74)  ali follow..  11  173......................................................................................................................................................................................................................................................................................................................................EAEEKMKNRRKTADGYQRWMMKAANNGPALFGEVDNEKESGGTSGGGGRGRKKSSGGDEEEGNVSDRGDEDEEEEASRKSRLGLNRKSNDDDDEEGPRGGDLDMDDDDIEKGDDWEHEEIFTDDDEAVGNDPEEREDLLAPEIPAPPEIKQDEDDEENEEEEGGLSKSGKELKKLLGKANGLDESDEDDDDDSDDEEETNYGTVT 377
13 -13.700[S] KOG4051 Uncharacterized conserved protein  ali follow..  15  227............................................................................................................................................................................................................................................................................................................................................EEQKMKSTNKTAAPVRKSQRLKRSKEVKFEDEEKEEIEEDNTKDEEQKEKKEEIQEPKITHNEEVDKEKNENEEGDDEREKSTSYENTNGSESEGVDEGVDEELGYESEREAEGKGKQIESEGGNLKKKTENKKGDDQQDDTKKDSKDKNEPLAKRTRHSSSTGNTSNETSPKRKRRKAGSRKNSPPATRVSSRLRNKK 425
14 -13.300[S] COG5291 Predicted membrane protein  ali follow..  9  212............................................................................................................................................................................................................................................................................................................................................................................................................NEHPSSCCKARKGITIREGRERHERNMGYSNASTTSGDSMASLTDMADTKSSTENSAVTEESQCCAESFKDSSVVSSQKSMAVSTVVGSSTEAKNNYLDFTEALCDKEVVAEQNPESQSNEEWDEKWGDSDNESE 346
15 -13.200[KU] KOG2773 Apoptosis antagonizing transcription factor/protein transport protein  ali follow..  14  28..........................................................................................................................................................................................................................................................................................................................................................................SAEDSDFDVATGPRLVDFEEEEYDLPDARSTDFRKRNVKLLSEQSDRYKGKISSRKELDDDEDKDDEQEVSYEESDEDDENLTNFKQKLNAGGAEDSEEETAAGHSESGEESEEIESNLTDFKKKFEAGDFKYDDDEEEDDDSEEEDHSQESEGDDDDSEDDEAEDDAI 196
16 -12.900[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  11  3.......................................................................................................................................................................................................................................................................................................................................................................................KKLALKRRGKDSEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQSSSAEEDEESSDEEDNEEEESTDGEEVEDEEKDSKSKQTDDKPSGSGAASKKALTAELPKRDSSKPEYQDSDTSDEED 158
17 -12.800[A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP) subunit - Mpp10p  ali follow..  11  109...................................................................................................................................................................................................................................................................................................................................................................................ESEEQEREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKD 268
18 -12.700[J] COG5593 Nucleic-acid-binding protein possibly involved in ribosomal biogenesis  ali follow..  10  699........................................................................................................................................................................................................................................................................................................................................................................................NDKYIKGKQARKTKVDRDEEGEIDEDEVWKALVDSKPQLEMDEEESDFDSEEMDKAMTDMGSDSEQSADENDNESMASEEKPMFSDEENLSEIAHSEDEFDDTVDFFEDENDLLPFNETDDEEEIQTVDHSETHSHKKKKRKAIKDLPVFADAES 853
19 -12.500[S] KOG4852 Uncharacterized conserved protein  ali follow..  14  153..................................................................................................................................................................................................................................................................................................................................................................................................................................................AKRDELDLGDEDDSDGPPADDEDDSNDEDNWRNDDEESYDEDSDNGDPYGISEPDHWHAGEEAYSDESFHRRLQNMDLNDERYEAFYEGDETDEDAD 251
20 -12.400[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  11  247............................................................................................................................................................................................................................................................................................................................................PGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDREREKKKKRSKSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEKYRPPPAHHNMFSVPPPPILGRGNASTNPNPDNGQQSSGDPSW 445
21 -12.300[S] COG5604 Uncharacterized conserved protein  ali follow..  8  3.......................................................................................................................................................................................................................................................................................................................................................................KLSSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETDAMAKEIDENERLKSSSGK 174
22 -12.300[J] KOG2256 Predicted protein involved in nuclear export of pre-ribosomes  ali follow..  8  3.......................................................................................................................................................................................................................................................................................................................................................................KLSSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETDAMAKEIDENERLKSSSGK 174
23 -12.100[Z] KOG3756 Pinin (desmosome-associated protein)  ali follow..  10  543....................................................................................................................................................................................................................................................................................................................................................................EPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
24 -12.100[S] KOG2889 Predicted PRP38-like splicing factor  ali follow..  10  170............................................................................................................................................................................................................................................................................................................................................................................................ALEEVDMLPSYKSLLDGDLVAMSDSDSEEEEVTKKEKPRLTSRRRSRSRDRERDVGDRREVREREKLKERRERGDDEPGPSSSGSGRRDDRDDRRRDRDRSRDRDRRDRRDDDRRDKKKESRRGGADNDEEREIAEANALRAKLGLAPLER 320
25 -12.000[K] COG3343 DNA-directed RNA polymerase, delta subunit  ali follow..  11  87.............................................................................................................................................................................................................................................................................................................................................................................................................................................DEIDEEIITLEEDEDGAQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDSELNEIIPEDDFEEVDINEEDEEDEEDEE 188
26 -12.000[A] KOG2242 Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain  ali follow..  11  4.......................................................................................................................................................................................................................................................................................................................................RRLKVNELREELQRRGLDTRGLKTELAERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFD 207
27 -11.800[S] KOG2690 Uncharacterized conserved protein, contains BSD domain  ali follow..  12  295....................................................................................................................................................................................................................................................................................................................................................................KDEVESTYSVAKVSTQDEVTSADSVTEVSNVGLKTDKDSEEKKETDSEEVPEEKSFVDAAPPASDEAPIQDSVKPTSDEAPIQDSVKPKSDEAAPSQDSAKPDVAASSSTQQPSEEDLGWDEIEDMSSIDGKETSRSGGSPNRAELRKRLSAAEEDEDLSWDIDEDDEEESSSSK 469
28 -11.800[R] KOG3263 Nucleic acid binding protein  ali follow..  10  20.....................................................................................................................................................................................................................................................................................................................................................................ESSRSRGDQRDRDYREYRRNYRDERSSRRYEDSQRRDYSPARRRDRYERHRESVREESPRRPVEHERNWQPELKHGRERFRERDYEGRRDRKERRDGVSPFSPEGEGLERKREHEKLQAPSPKEEEERPVDQGDKMDGVKEDKDGSLEVGKSHDAMTRTKSAEEEIVEQEDEAT 193
29 -11.800[Z] KOG3809 Microtubule-binding protein MIP-T3  ali follow..  14  137.............................................................................................................................................................................................................................................................................................................................................KGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEIST 334
30 -11.800[R] KOG1400 Predicted ATP-dependent protease PIL, contains LON domain  ali follow..  11  2................................................................................................................................................................................................................................................................................................................................................................................DEEENSEINSVQARDEDVQLEDQQSQGLQDRQVDVIEQAWNNAMPDEPSPPAEDAFQDPLATDGEGGDALEAMVENVLQDDTASEGSHPSSDMSLESPGSEDDSDLESLPHWMIPQNRLRSAVDSQERRRSRTSEETSQEAAEQPVDPPPQQPPRPPIDIGFD 195
31 -11.500[S] COG5139 Uncharacterized conserved protein  ali follow..  8  2................................................................................................................................................................................................................................................................................................................................................................................................SEEEKAELENMQVESEAKTSENDQTIDTKVDVADVTTHVDEDLDNKEEALDFSEDELSDLDENQFENFDESKIGREAEEPTIYNLPTFKKKQEPNTIEENLEVPRKVRKEQKPRRRRGKRSSTVDALNDELNELGENEEEVLTEQKQ 148
32 -11.500[J] KOG2147 Nucleolar protein involved in 40S ribosome biogenesis  ali follow..  8  104..........................................................................................................................................................................................................................................................TDDGDEEEEVLTHKGKALSDIEKYDKSMISDSDDDEEPGNLGSNMVKVAHFGGGEKTAEEHVREKISREDMISNLIAKTKLARHEKQQQKDELELMTESLDSKYQALMGKMKASFRPTGRQPLEKDDYDKLTITLKTEADARATPADRKLSEEEEALKEKERLETLEAAPDADVDIDAGSKADARKVQAKNSRFEVKFDDEGGLIDEDTVEKSRILKKNLDGSDESDDDEDLEDEEEDLDDLLEDEDELEEDSDDEEAQEAQKVVKKAKKSAPEPAET... 381
33 -11.500[K] COG5164 Transcription elongation factor  ali follow..  11  1...........................................................................................................................................................................................................................................................................................................................................MSDNSDTNVSMQDHDQQFADPVVVPQSTDTKDENTSDKDTVDSGNVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDDDEDDDDEAPTKRRRQDIEAEVSDDEDEDEDEEDSELVREG 206
34 -11.200[A] KOG2217 U4/U6.U5 snRNP associated protein  ali follow..  9  6............................................................................................................................................................................................................................................................................................................................................SGKKHKKDKKNRHRSRSSERPRRVTEDEDVTLDLTDDSSSRHRHHKHKKHKEHRHKHHKQKERERANEVISLEESDSDSSDCVEVPVQAQVQAQAKLRDARESSNRDKERDSGRDRELLRERERERDRERERDRDREKEREREREKERLREREEREREREKERIREREKERLRERERERERERVRELTAPPPPQISKHA 204
35 -11.100[J] COG5384 U3 small nucleolar ribonucleoprotein component  ali follow..  8  89....................................................................................................................................................................................................................................................................................................................................................................QDEDDETSHQELSDNSEMNNRDDADDEFLGFSGPENLEDVDESSAEDVSGDEAEIMNEEGQQIEQKKDAFGLNDGFFDIDNFNKQTLALEEEAVEEGVLGDEDDGIDLLMDPDENMEDSEDESNGPQADSIMYEDFFGPKTAAGRRELKKKKAESKRKRTSKPDFKNDVQQNVIE 263
36 -11.100[BD] KOG4563 Cell cycle-regulated histone H1-binding protein  ali follow..  9  115...............................................................................................................................................................................................................................................................................................................................................................................VEEEEGEKTEDESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPETDKEQDSEMEKGGREDMDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVIVSIEEKPKEVS 278
37 -10.900[R] KOG3175 Protein phosphatase 4 regulatory subunit 2 related protein  ali follow..  14  241..................................................................................................................................................................................................................................................................................................................................................................EGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
38 -10.800[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  5  172.....................................................................................................................................................................................................................................................................................................................................................................................................................HVKLVSRELRRKLFGRYRRSYRRGSRSRSRSRSISPRNKRDNDRRDPSHREFSHRDRDREFYRHGSGKRSSERSERQERDGSRGRRQASPKRGGSPGGGREGSEERRARIEQWNREREEKEEGGA. 296
39 -10.800[R] KOG2950 Uncharacterized protein involved in protein-protein interaction, contains polyproline-binding GYF domain  ali follow..  8  4...........................................................................................................................................................................................................................................................................................................................................................................................TLRNPGNSSTVGDVHDVFFEYDVSNVGRKRPRTKEEGYYESESEEDEDQILNKEKKEGQSEDMFSDTSEDEKRTLPNDEAQKRRDFIENGDAERLAHKGLRNKEVLNDDSDDEDDNGKYSKLRYEDIEGQEDTNQANDLDADEEGSEISVPS 155
40 -10.800[K] KOG4134 DNA-dependent RNA polymerase I  ali follow..  7  199.........................................................................................................................................................................................................................................................................................................................................................................................................NITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPLKCSPKRKGKSN 336
41 -10.200[S] KOG2827 Uncharacterized conserved protein  ali follow..  11  194..........................................................................................................................................................................................................................................................................................................................................DLNGRRMASVDEEAKLKRYLEKQARKEQELKEKRKAKLEKLTAGPAKHMFEDQDYLSRREEIINKTEDACEAGFALMLEMKRNSRKSKEQENKNDEDEDDDVNAEDVTDLFNDRGGRKRKIAAPSIGEDGGNKRINDESDDSEDDSENEVDPEELEAIRQYFEAKKQDEKDNGEGTSEAVPEVLVDEQEIEPAKRPRLDSA 394
42 -10.100[S] COG4530 Uncharacterized protein conserved in bacteria  ali follow..  10  43.............................................................................................................................................................................................................................................................................................................................................................................................................................................................ETSVAKVLEKEEEEDVKEVDTENTEVELVSLEEADDEASGGDDLPDLGDDDVEIEGDDDDTFLQTDDEDDDDDMSDIIGVSDEDDD 128
43 -10.100[R] KOG2888 Putative RNA binding protein  ali follow..  9  222....................................................................................................................................................................................................................................................................................................................................................................HQLSTGRSTAGTGGGPGAAGQDADYQDYPEGGVERGSGGRGGGQAGSRSNAYPQPNNYRNDYDERDYYAAASGSSYGRGRGGYEDYPPAPLPPQMPYGERERERDRDRDKNKDYDRHRSKHKKKHNHRQSSRSRSRSRSRSRHRSERHERKRDGGGYERSSKSRHNEHYEERERR 396
44 -9.910[K] COG5414 TATA-binding protein-associated factor  ali follow..  12  348......................................................................................................................................................................................................................................................................................................................................................................HTIASAVGKQGAEEEGEEGMEEEEEEDLDLGAAFESEEEGSGAEGDKEQQQEEVGDEVDQDTGGEDDDDDDDGDIEAAGGESESDDEKDEEDSVQKQHQHRSDAETANNVEEEEEEEEEEEEEDEVDEDEEDDEENDEDEDNVHEREHIQENKVVRELDEAPAEETLDQNDLD 579
45 -9.870[R] KOG4095 Uncharacterized conserved protein (tumor-specific protein BCL7 in humans)  ali follow..  7  53.............................................................................................................................................................................................................................................................................................................................................................................................DSKEKEKSKSNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASE. 201
46 -9.870[M] COG3064 Membrane protein involved in colicin uptake  ali follow..  8  31........................................................................................................................................................................................................................................................................................................................................WSSFDEHIEASAGGGGGSAIDAVMVDPGAVVQQYNRQQDQQASARRAEEERKKLQQQQAEELQQKQAAEQERLKQLEKERLAAQEQQKQAEEAAKLAQQQQQQAEEAAKAAADAKKKAEAEAAKAAADAKKKAEAEAVKAAADAKKKAEAEAAKAAADAKKKAEAEAAKAAAEAKKKAEAEAAKAAAEAKKKADAEAAKAAAE 233
47 -9.590[S] KOG4149 Uncharacterized conserved protein  ali follow..  11  106....................................................................................................................................................................................................................................................................................................................................................................................QRHRIEDAIEKKMTSETQPSTDEKGRKVSATENSAPKKTDKEKSSGETAGNILREQIATGKDDDEYARKFEEVEEESSEESAFNPDTGEINWDSKSEPKGMEGESEEEDAETNEKPSTTSDENNQPQSPPSDNASNPEEDVMNMEKEIVNLTPMSVIKE 312
48 -9.540[JK] KOG2038 CAATT-binding transcription factor/60S ribosomal subunit biogenesis protein  ali follow..  9  819................................................................................................................................................................................................................................................................................................................................................................................KKVAVKEKQKRDADEESIEDVDDEEFEELIDTFEDDNCFSSGKDDMDFAGNVKKRTKGAKDNTLDEDSEGSDDELGNLDDDEVSLGSMDDEEFAEVDEDGGTFMDVLDDESESVPELEVHSKVSTKKSKRKGTDDFDFAGSFQGPRKKKRNLNDSSLFVSAEE 981
49 -9.520[S] KOG1793 Uncharacterized conserved protein  ali follow..  10  2..................................................................................................................................................................................................................................................................................................................................................SDHEEESHGASPTSPASSGASSPLAPISPRSEGNAPESPSGDVQDIYKDESFEAPASPARDSSAPASPSAASPAGSRSPSPSPVKTKSKVMIDSDEDSDAEESANKRALIDSDASDAEGKKRRVMLDSDDSDHEGTSKKEPTTKNLFGDDSDDDDEDRPKKTNDLDEFVEGRDEEESQETSKPAYDSDDDDGP 194
50 -9.500[A] KOG4746 Small nuclear RNA activating complex (SNAPc), subunit SNAP43  ali follow..  9  244............................................................................................................................................................................................................................................................................................................................................GVDEIVHTDHSAQQLASRGMQRSSIKDQAHSAALKFSRTRRHRSVKPVIVPAETFEYAPDPKKKKEAQETMPVSGRNGRKRGRPKSVPKSKVSNPARILYEKLAEDMISEHLSTDLTEQEAFTDRPQSSLEPQKNELFNWDAAPQDAQISNQTTEPSCGEDIFIEDFGEFKSQDDVMFTAEDFNDSLIPPLADSDSDLE 442
51 -9.390[T] KOG1882 Transcriptional regulator SNIP1, contains FHA domain  ali follow..  9  1...........................................................................................................................................................................................................................................................................................................................................MKAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGS 200
52 -9.250[K] KOG3794 CBF1-interacting corepressor CIR and related proteins  ali follow..  3  395............................................................................................................................................................................................................................................................................................................................................YRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEE 593
53 -9.240[A] KOG2253 U1 snRNP complex, subunit SNU71 and related PWI-motif proteins  ali follow..  8  37......................................................................................................................................................................................................................................................................................................................................YSHSFVPSIRFISIILKLLPLLMNTNEIAIDAAAVAQGAEKELHDDREAKNRPEASKRSRRSRSSSNSSSESDSSSSRSSSYSSRSRSRTPQRSRTSKRRRSNSHASEDSDDAREKRAFKQMMLDKKQAYLARLKRWESRERQMSKRYEREERKEKDRKKTLQKEGKRLKLFLEDYDDEKDDPKYYTSSQFFQRKRDYEREREAD 241
54 -9.160[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  8  10............................................................................................................................................................................................................................................................................................................................................DDGKRVQNEEGNYDPTDHQRQMEDYYKQYEEQRQVANSFHNTTGRPDLVAMQARLAETEQAIHRLNEEKKQPPPGFPIMTTPATQPEISIPRSGENKSSRSPSWAREARRSRSRSRDRRGGRSRSRSPSRRRTSRDRRDDRSSRRRRDRSHSRSRSPPSSANGSSHWSSSNRHSRRRRSRSYSRERDRNSRRDDRRSNL 208
55 -9.150[S] COG5644 Uncharacterized conserved protein  ali follow..  9  1...........................................................................................................................................................................................................................................................................................................................................MARKGKVNTLPQPQGKHQRKGKKQLENKILHSYEEESAGFDSEELEDNDEQGYSFGVNSEDDEEIDSDEAFDEEDEKRFADWSFNASKSGKSNKDHKNLNNTKEISLNEEDDSDDSVNSDKLENEGSVGSSIDENELVDLDTLLDNDQPEKNESNTASTIRPPWIGNNDHATDKENLLESDASSSNDSESELTDSADNMN 200
56 -9.140[S] COG3767 Uncharacterized low-complexity protein  ali follow..  5  2...............................................................................................................................................................................................................................................................................................................................................................................................................................................NKNIAAALAGALSLSLAAGAVAANKPASNATGVHKSAHGSCGASKSAEGSCGAAGSKAGEGKCGEGKCGATVKKTHKHTKASKAKAKSAEGKCGEGKCGS 101
57 -9.080[R] KOG4520 Predicted coiled-coil protein  ali follow..  9  106......................................................................................................................................................................................................................................................................................................................................................................................EGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGSE 262
58 -9.020[R] KOG2140 Uncharacterized conserved protein  ali follow..  10  692......................................................................................................................................................................................................................................................................................................................................SSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQ 896
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;