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Query: [K] KOG2593 Transcription initiation factor IIE, alpha subunit, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MVKLVAKTFYDNYTPKNNNQKKSAKNGSGGIAVLVLDALTRRQWVREEDLAKELKLNTKQLRTILRYFEEQQFIMRVHRKEKSSATTNGRGEDKVKVHMYSYCCLDYSQIYDVIRYKLHRMKKEFKDVLEDKDNVQEYGCPNCKRKIFFHCENCNGELVMECNKLTSEEVVVDGSDNPRSRRDHLKDLLQNMEVRLKPLMDHINRIKDLPVPSFESFPAWETRVAKAARENGDLNPDDTLRPQGGYGSTPMPFLGETEIEVNLGEENEDVKSDEVGDSSRRKLTPSWLIKKGMNLSDEQRGEIRHEAKADDGGSSMENGDDDRNLKDEYLKAYYAAILEEQELAEKLNQQESAGKVTTDIELATSSSDRQVGMKSKREEEEEEEASVAANGNYKVDLNVEAEEAEQDENDVDWQECLast
1 -107.000[K] KOG2593 Transcription initiation factor IIE, alpha subunit  ali  100  1MVKLVAKTFYDNYTPKNNNQKKSAKNGSGGIAVLVLDALTRRQWVREEDLAKELKLNTKQLRTILRYFEEQQFIMRVHRKEKSSATTNGRGEDKVKVHMYSYCCLDYSQIYDVIRYKLHRMKKEFKDVLEDKDNVQEYGCPNCKRKIFFHCENCNGELVMECNKLTSEEVVVDGSDNPRSRRDHLKDLLQNMEVRLKPLMDHINRIKDLPVPSFESFPAWETRVAKAARENGDLNPDDTLRPQGGYGSTPMPFLGETEIEVNLGEENEDVKSDEVGDSSRRKLTPSWLIKKGMNLSDEQRGEIRHEAKADDGGSSMENGDDDRNLKDEYLKAYYAAILEEQELAEKLNQQESAGKVTTDIELATSSSDRQVGMKSKREEEEEEEASVAANGNYKVDLNVEAEEAEQDENDVDWQEC 416
2 -45.500[K] COG1675 Transcription initiation factor IIE, alpha subunit  ali follow..  17  4..........ETTTGVEELLNELVGRAAG-EVGLILFSLGIEGEFTDDQLSLELGIEINEIRKALFALYEIGLADYVRRRDDETG------------WMEYYWRINYDKALDVLKRELEKTAKKLREKIEAETSTIYYICPNMCVKVSYNDAMELNFTCPRC-------GAMLDYLDCSKAIEKIEEEVRRIEEILESLDKN...................................................................................................................................................................................................................... 175
3 -14.900[K] KOG2587 RNA polymerase III (C) subunit  ali follow..  8  366.........YKSIISVAQKDEAVVMRRYGKEAFRMFRYLSQERFVETDKIADAALTEKKDTPQFLLKMWKDGYLHMQKLAVTAPGMYT----------PFLLWKVNKLIVTTQMLDEMYHASLNLSLRLAHELEAEKELLLLPLDKLEGPL----------------------------------KERLKKVKAKRLLLSSTMFKLDDAIM............................................................................................................................................................................................................. 524
4 -12.600[K] COG3355 Predicted transcriptional regulator  ali follow..  14  1....MAEKVRFPDGREVDIHDFIAFMYLSKSDVEVLHILLQNGKMTTDDLSQKLNVTKASISKALNNLLDKGLIQREKAPAEKE---------ERKGRPNYIYWVEKERLYRKLEADLEKLAGTVKEALQKH............................................................................................................................................................................................................................................................................................ 120
5 -11.700[K] COG2345 Predicted transcriptional regulator  ali follow..  14  10.......................AHTGDGDTRRKILLILLERAPVIASDIAEQLQLSTVGVRRHLDNLVEENLAEAANPRQNPYEPKMRLTDKGRSIFGHEYDSLAAAALATLIEDTAKSLVEAFSRATRNGLQLCQHHCP-CEAEHQAVSTQPLATIADGHGICTTNIPLTPIKHS............................................................................................................................................................................................................................................... 228
6 -11.200[K] COG5625 Predicted transcription regulator containing HTH domain  ali follow..  14  2..........KQEEMLKKLEDLLKAIGLKKNEIRIYRLLVERRGMRIREIQRELGISERSVRTHVLNLYRRGLLKRELVQS--------------GWLGYIYTPVSPLEILQKIKEHLMKSIEELERDLKNQTRS......................................................................................................................................................................................................................................................................................... 113
7 -11.000[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  10  163......TRYFQNNSTYGEEEKKVVSALQNATNQRIISEIQNGKCNTNLALAREIGVSRATISWYVKNLKETGLID------------------ETRSGRSIIYSINPSYEPLIEKY............................................................................................................................................................................................................................................................................................................ 254
8 -10.700[K] COG4738 Predicted transcriptional regulator  ali follow..  11  23................YEMVELLRRLNINRPVALTLACLSKGDEISSQRIEMVSGLRQPEVSIAMRYLRENEWVDMREEKKNHGKG---------RPVKLYKLTVQMETIIDTIEENVIAESKTILQNIERLKS.......................................................................................................................................................................................................................................................................................... 131
9 -10.400[S] COG4344 Uncharacterized protein conserved in archaea  ali follow..  10  1...............MSEYEKEIDELINDYDMLRVLKHFTIAHVDYAKNITRYTEIPQMRVREYLKRLKDLGLLDYYTNTSIKRTEAKLKKSAEVHKHHTYY--------------QINKKAEAVLKEITPKLYVH........................................................................................................................................................................................................................................................................................ 107
10 -10.200[S] COG3388 Uncharacterized protein conserved in archaea  ali follow..  23  18.............................KRHISVINVLLREQPIGIIKLSQETGIPEHKIRYSLRILEQENIIS..................................................................................................................................................................................................................................................................................................................................................... 63
11 -9.740[S] COG4519 Uncharacterized protein conserved in bacteria  ali follow..  2  9..............................RRLYLALLVESLERPNVPKLIEKTGWPRRTIQDVIKAMPGIGIELNFVQD................................................................................................................................................................................................................................................................................................................................................ 58
12 -9.700[K] COG1846 Transcriptional regulators  ali follow..  6  13ASLRLGRLILQLRRLESTPRTFGRAGALTPSEIHTIDAIGTDEGLLMKELAERLGVTKGAVSQLVDRLEAKALVRRTAHPKVSRGIQVVLTDKGREAYRAH------KEEIAIFEQCVSKLRDILSE................................................................................................................................................................................................................................................................................................. 149
13 -9.340[P] COG0735 Fe2+/Zn2+ uptake regulation proteins  ali follow..  13  6...........................LTKNQSLVMGALAHDGPMSAYTILDKLRDNGFRVYRALDKLLEYGLVHRLESLNAFVACSCPHEHEHDHGVTAFTICEGCGQVTEFHDEVIEDRLSTLVRAQEFKTEKTTIHCKSCA................................................................................................................................................................................................................................................................................ 131
14 -9.150[K] COG1378 Predicted transcriptional regulators  ali follow..  10  9.IKKVYNFVVTFVVTMDEIIEVLKRLGFRDYEARVYATLATRGEATASEIHRVSGVPRNKVYEVLRSLEDRGMIETIKSSPAV------------------FRAIDPESVLEEYKEQLVSAVDTAIRSIRESEDFS........................................................................................................................................................................................................................................................................................ 125
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;