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Query: [R] KOG2647 Predicted Dolichyl-phosphate-mannose-protein mannosyltransferase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAKALESNSKSRKETILIKYAIFSRLLVLFLTILWRSLLQPYDTSAALNPPCLYHKEDSFPFLVANAASRSLENSVVWDSVYFLRITECGYEYEQTYAFLPLLPFFISLLSRTVFAPLVPLIGLRAVMVLSGFTVSNLAFIFAAIYLFRVSVIILKDTEASFRASIIFCFNPASIFYSSIYSESLYALFSIGGVYHLLSGTSNVGVLWFALSGCARSNGILNAGYICFQTMHRAYEALYQKRRAYLAMQVFIAGFLRCICICLPFVAFQAYGYYNICHGHTRDEVRPWCKGRIPLLYNFIQKILVSDRGVGFLKYFQFKQLPNFLLASPILSLAVCSIMSYMKSRPELFISLGFQATEKEKRSAARLYSLKDAVEPSVKTSTNEGNHDIRQRKPSSKKDVTGTKVAPEKSGYLSADVFPFIVHLSFMVTTAFFIMHVQVATRFLSASPPLYWFASSLIGSPKHSKWGYLIWSYCAAYILLGTLLFSNFYPFTLast
1 -131.000[R] KOG2647 Predicted Dolichyl-phosphate-mannose-protein mannosyltransferase  ali  100  1MAKALESNSKSRKETILIKYAIFSRLLVLFLTILWRSLLQPYDTSAALNPPCLYHKEDSFPFLVANAASRSLENSVVWDSVYFLRITECGYEYEQTYAFLPLLPFFISLLSRTVFAPLVPLIGLRAVMVLSGFTVSNLAFIFAAIYLFRVSVIILKDTEASFRASIIFCFNPASIFYSSIYSESLYALFSIGGVYHLLSGTSNVGVLWFALSGCARSNGILNAGYICFQTMHRAYEALYQKRRAYLAMQVFIAGFLRCICICLPFVAFQAYGYYNICHGHTRDEVRPWCKGRIPLLYNFIQKILVSDRGVGFLKYFQFKQLPNFLLASPILSLAVCSIMSYMKSRPELFISLGFQATEKEKRSAARLYSLKDAVEPSVKTSTNEGNHDIRQRKPSSKKDVTGTKVAPEKSGYLSADVFPFIVHLSFMVTTAFFIMHVQVATRFLSASPPLYWFASSLIGSPKHSKWGYLIWSYCAAYILLGTLLFSNFYPFT 492
2 -92.500[S] COG5542 Predicted integral membrane protein  ali follow..  22  20.AIRMTRSGYNYFKGICVCTFLLSTILYLGIAVIMSHLCVFDDTAMLYLR------QNRSRLAESNIFRTLFISWIRWDAIYFVDMAVNGSLFEQEWAFSSLWPKIISFLAFRS--------KDVVLLGIVSCFASIFFHAIACYALYLLTKSIFSNQKMTAYTVIFYCFSPSGIYMSVGYTESLFAAFSFLGLLLFIKKQQYPAAFLWSLATLIRSNGIFWCIFFGMPAIGTLKISLERLQLTFMQVSQLVGYGTKCLIILVPFFYNQYLGFKLFCPG------VAWCNKSLPLIYPAVQEKY---WNVGFLRYWTLNNIPNFLFALLSIIPILFALFYSISGSTL----------------------------------------------------------------HSFRSIKSHLVLSALYLYIGCFHMHTQVLNRMSSALPLLYWSMAHATLYAKSRNFGHCILFVWIVYTVIQAGLYGSFLP.. 424
3 -15.000[O] COG4346 Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase  ali follow..  12  154.............................................................................GYKYPDEENIHKYLNTEH-----FLGKDIIALGMLIEDKPFY--------------IPGIIEHALIVIIVTLVAYKITKSYLASSIAATFAALDPLLFATGVAMLDIHVAFFIALFMLFLALDRIRLSGIALGLAAATKLSGAFAFPILWFKILKEKDLKEYLISGLVLPMVSFLIPEITIIKAIGFIPWLEEFIASFSWHLSFKGEHPMWFVSLKPFPFHFDPDVYAVIIAFFALQYILGGKT-YATPLIPPGAVALGVISYEIIK.................................................................................................................................................... 449
4 -14.400[R] COG1287 Uncharacterized membrane protein, required for N-linked glycosylation  ali follow..  10  1MANSATITSKKGVKSHQKDWKIPLKVLILICIAVASVSSRLFSVIRY---------------------------IHEFDPWFNFRLVEQGLNWFDERSWYPL-LYPGLMVTSGIIFKVLHLLRINVNIRDVCVLLAPAFSGITAIATYYLARELK-SDACGLLAAAFMGIAPGYTSRSVA-NEAIAITLLMSTFALWIKAWGACTGLLYFYMVTAWGGYVFITNMIPLHVFVLLLMGRYTSKLYIAYTTYYVIGTLASMQV....................................................................................................................................................................................................................................... 260
5 -14.100[O] KOG2292 Oligosaccharyltransferase, STT3 subunit  ali follow..  13  1MNRTPKMNSKVAGYSSLITFAIL--LIAWLAGFSSRLF-----------------------------VIRFESIIHEFDPWFNYRMVQNGLNWFDERAWYPL-VYPGLMITSGGIHWLLHVLNIPVHIRDICVFLAPIFSGLTSISTYLLTKELW-SAGAGLFAASFIAIVPGYISRSVA-NEGIAIFALQFTYFLWVRSWSAAAALSYFYMVSAWGGYVFIINLIPLHVFVLLIMGRYSPRLLTSYSTFYILGLLFSMQI....................................................................................................................................................................................................................................... 255
6 -13.500[O] COG4745 Predicted membrane-bound mannosyltransferase  ali follow..  11  1.............MRRSRDDSSPRVAAAVVAVTAAALLARLWALGWRVA---------------------------HQDADWTLQYMDLGAWQYRPIIHGPFLPHVNGVVFDVFGAT------------FTMRLVVAVVGGLLPLTAWLYRTRL--SDVEVGALAVLLAANPVVLYYSFMRNDLLLAGFMFTAVGLFRARYLYASAVPFALAFTTKENSLLYPLCWLGALA..................................................................................................................................................................................................................................................................... 190
7 -13.400[O] KOG3359 Dolichyl-phosphate-mannose:protein O-mannosyl transferase  ali follow..  8  66......................VMPVIFTALALFTRMYKIGINNHVV------------------------------WDEAHFGKFGSY-YL---RHEFYPLGKMLVGLSGYLAGYDFLLEIYPDYLDYVKMRLFNASFSALCVPLAYFTAKAIGFSLPTVWLMTVLVLFENSYSTLGFILLDSMLLFFTVASFFSFVMFHLLITGISLGCTISVKMVGLFIITMVGIYTVIDLWTFLADKSMSWKTYINHWLARIFGLIIVPFCIFLLCFK............................................................................................................................................................................................................................ 305
8 -13.300[O] COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl transferase  ali follow..  11  65.....................................................................TVLGMFTRWDEAHFGKFGSY-YL---RHEFYPLGKMLVGLSGYLAGYNGSWDFPSGEVYYVKMRLFQAMFSSLCVPLAYFTGRAIGFSRLSVWLFTILVIFENSYATLGFILLDSMLLFFTVSSYFCLAKFHLCLTGLNLGCAISVKMVGLFIISVVGIYTISELWNLLSDRSVSWKVYVNHWLARIFGLIIIPVCVFLLCFK............................................................................................................................................................................................................................ 299
9 -13.200[G] KOG4123 Putative alpha 1,2 mannosyltransferase  ali follow..  10  3LTTLWQNRSPGDRHLSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFR----------------LEHTRTWE--FNNSLPVRSIVL---FALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYGLR---FEIRLLAMGSSWILLVFGTTFSNSLEMAMCSWLLCLVNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMP--MLFNVLALASLGAFAQLLLRF-----------------------------------------------------FRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLIN----HQEP--RLLPVTFPLILLHAPKLITLSSKASGPYLLKIWYVSNVALTLFFGFI.... 474
10 -12.300[S] COG5650 Predicted integral membrane protein  ali follow..  9  37......AQVGTQRFWTPLRVLITTSLVFLAMGFLANCIQGSRGTDGVVS--------------------------LNWDPLYGGRGIDAPYAFSWQEGDYPVLGGIFQWICGIITRFLYPVVDVIPFHTLPESGLYFIVTALALAFFWVLVIRMMVETGNRVWDTVLVAASPLVAVHAFTNWDTPAIAAVIGAMLAVKRGNPLVAGVLIGAGTAFKLWPLYLLGAYLVLAVKN--------KNLKPFITMAAAAAVTWLVVNVPVMIAYPKAWNEF........................................................................................................................................................................................................................ 298
11 -12.000[OKIT] KOG2642 Alpha-1,2 glucosyltransferase/transcriptional activator  ali follow..  11  1MTKSKPPRISLPFAAISRKSDFLLGASFSCIHVLLTTIVYHYVPEPYM------------------------------DEIFHISYCSGNYSWNPLITTPPALYVISMPLCGGNERYANSILLFFAIPAFC-RFRRMFVRVRIPTLKIYLKNTD--LQQDVWLTASIVGMLPILISSSILYTDLLSLTSVIWGFSI---GNPIASAFLFLISILTRQTNIIWAAIYAFSVIASRIDKSRSKMENLKIIISTAFSLWPFITLAIGFAMFIYFN----------------------------AKAHQPKFHVAQFFYMVA-----AAHTWTQIIPNLLSHLRHLTDMKSLVLQAVVAVLVYYYSYDHPYLLADNRHFTFYIWRRFLANPTMRTTLAPLYVFSLRFMTTSTPSVHIFHKILFIIASLLVLVPAHLFEMRYYII-------PYVLW----RLSTVNNSRKSLLFL--IISQAVIFAANEFVQKQKN 428
12 -11.400[MU] KOG2515 Mannosyltransferase  ali follow..  9  1MPSKAPRKSLSVSFVWTFSILAVLRLTSASFRVIDD------------------------------------EVYNYWEPLHYL-LYGYGLQTWEYSPEYAIRSWFYIALHAVPGFLARGLGLSRLHVFYFIRGVLACFSAFCETNLILAVARNF-NRAVALHLTSVLFVNSGMWSASTFLPSSFAMNMVTLALSAQTKRTVKVVSFITIGAVIGWPFSAALSIPFILLELVDLKGRFRHLFCRWFKAIFVALLITGICITVDSLFYHRIQ-----------------------VKYNVLAGRGPDIYGTEPWWYYFANLSLQHNIVLWFAMACGPLV--------------------------------------------------------------LLAAFTNWINLDSFLDLSSVISPFYIWLFIFIIQPHKE--ERFM-IYPVLCLAAAIGLDM................................ 352
13 -11.200[R] KOG2552 Major facilitator superfamily permease - Cdc91p  ali follow..  10  1MKEEKKDDGVMAEEKPYMFWIWTLASTIFRLFLIFSPANINLSSRPEVSTPHTSLRRLA-------------------EGYWLKQSSLSPYAGS-----YHGSPLLLSILGPLTV-----QSDKFVVAGSKGNRVIICADLLSALLLRAIGQKLQKSYRCGDIAALVYLWNPFTILSCVGLSSPIENLAVIVSLYGAVTRRVPLAAFGLIMATHLSLYSAPLVFPLIFLLGYGLLPFSWRTVLHFVFWVLVWSSYVLVLCSLSLKQYGGLEEM-------------------FKRTYGFILRIEDLSPNIGVFWYFFAEAFEFSIFNLYILLTSIPSLMFRLKHRPCFLAFA------------------------------------------YLAFTSILKSYPSVGDAALYLSLWALFVNELTDMEYSFFIFCGYIGFSLLSPVMHNFWIWR-------GTGNANFYFGNAMGYACFQFMFVEKSV... 454
14 -11.100[S] COG5617 Predicted integral membrane protein  ali follow..  11  2...........KRKLYYLTLATISVIEYIPLYLAPSPPALQINGNGHLF----------------KVHKLMTSGWKPWIEDWY-----AGYPF---LRFYPPLSYLTAGVLGKVL----------GSDTKGYAATLMLTSFLGALALHHYLKST---GREPCISPLIFLLFPTVSYIEGNFPRANLAPLFLLSLYWLREKRLIASALGISIVALTHYSILPLLIITGILIL---WDDLRTMTALGNGIKVLGAVIGLTSFWYVPFLF................................................................................................................................................................................................................................. 226
15 -10.900[G] KOG3893 Mannosyltransferase  ali follow..  10  424..SSLYLLYAPTDAFLLLLLGLLMRLVLLNYGIWHDRRSALKFTDIDYFV----------------------------DASKYVSIGMSPYM-RDTYRYTPMLAILLLPTQYGFP--------------SWGKYLFSISDLIAGWLMIKLLSRR-ISYKRSLIYSSFWILNPFVAIIST--CEAILGILSIALLYLIEKKSVWLASLILGFSVHFKIYPFMYGIAFLVYFSKPKKGSTFMEKFLSLLSINQLKIVVGSLFMFTICNLLMYYLY-----------------PFLEHTYLYHFGRTDHRHNFSLHHLNLYYESSFGFAFLPQLSLCMLIPLVFGKKNLPGTLFA------------------------------------------------------QTFAFVTFNKVCTSQYFMWYLVFLPLVLPNSKLLSKKGLICLSLWWLISAYNLEMLGKSVFIPLWLSGLLFFFFNVYELKIIL... 812
16 -10.300[M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family  ali follow..  10  27..........................................................................LWQPDETRYAEISRE--MLASGDWIVPHLPIAGYWINSIGQWLFGAN--------FGVRAGVIFATLLTAALVTWFTLRLWRDKRLALLATVIYLSLFIVYAIGYAVLDPFIAFWLVAGMCSFKSAGFLLLGITCGMGVMTKG-ALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLAIA-HYFFWVEHIQRFALDDAQHRAPPWLGLLPGALYTGWKNVYLLSWTIMPLLFFSVAKLPTYILCFASLAMLMAHYA......................................................................................................................................................... 331
17 -9.910[G] KOG2762 Mannosyltransferase  ali follow..  11  29LKDGVRYVIFDCRANLIVMPLLILFESMLCKIIIKKVAYTEID----------------------------------YKA-YMEQIEMIQLDGMLDYS--PLYPAGHVLIYKMMYWLTEG----------DHVERGQVFFRYLYLLTLALQMACYYLLHLPPWCVVLACLS--SIYVLRLFNDCFTTLFMVVTVLGAKKSLALVISATYSMAVSIKMNALLYFPAMMISLF------ILNDANVILTLLDLVAMIAWQVAVAVPFLRSFPQQYLHCAFN--------------------FGRKFMYQWSINW-EAFNDKRFHLALLISHLIALTTLFVTRYPRILPDLWSSL-----------------------------------------------CHPLRKNAVLNANPAKTIPFVLIASNFIGVLFSRSLHYQFLSWYHWTLPILIFWSG---------------MPFFVGPIWYVLHEWCNSYPPN 413
18 -9.820[S] COG5305 Predicted membrane protein  ali follow..  9  1................MFSLGNSFLPVPLDQAIAPDILLQPLQPNP------------------ASGIGDVIHNLITEDN--------------------PLYFVLVHLWMKLFPN------QGELVSLLAARSFPALLGAVSIPLTYILGRLAFRSSLVGQLAAGMMAVSPYAVYLGQHYT--LAMIWVIASLSCLVIWLIILWVGINALGIATHYFFTLTLCAEALVLIFLAWQQSTQAKTLVFFSPLWWRIYAVAAGTAVAGLVWLPSILENR----YRSSLTAWIQVQGIGLHLINPIFQAFAAWVTMIMLLPIESSQLAVVIASGLVMLIFAIW-----------------------------------------------------ATPILVRGFKFQLQQPQTSLATQVFIGVVLGAIALFFILTYIFGVDITRRYFVYFPAVIILVGASLAVYWQTSKKAVMIIWLMG--FVSAVTVICNLGY. 391
19 -9.600[S] COG3463 Predicted membrane protein  ali follow..  11  2........KSLIDKKLLVIIFIAYTFIIFKTCLVENFSYKSLDLGIFSQSLYSTLNGKFMYNTVEAQLYSAPNHF----AVHFQPIL---------LLLLPVYPVVL-------------------------LLIQAIFLALSATLALLIACEEL-NHREAILVASLYIFNSSGIALFEFHPVSLAVPLFFIAYMLLKRGKMKLFYLTSVLILLTKEDSFLGVVSLSLWKILMDGLNPESFRKNRGLILLSIASMMYGIIV....................................................................................................................................................................................................................................... 224
20 -9.480[MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/PIG-B) involved in glycosylphosphatidylinositol anchor biosynthesis  ali follow..  11  3..............IWFWLAILVFRWWNALWV--KTFFQPD-------------------------------EFYQSLEVAHHFIFRYGFLTWEWTSAI--LHPLIFAALYRVLQ--VLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFALVRY-GSKTANWTLACSLVSIMNAYVGVTFSNSLETTLTSIGFYYFAYSSLLGFISVAAFACFIRPTNILVWIFPLLFWNKNPQTPIKDLLSFSNVFNRLFGIFVLCVSLFLVNIIADRILY------------GRFVFPIISFFQFNVTSGLSSLYGLNAWHYYLSQALPLICGGFLPFVLL--------------------------------------------------------------------------------TMDLQTAGTILCVFFPYSLIGHKEL--RVYPISPILLTLAGKFFSSFSSWKRAARFFFLIGLGHALVITFLCRF.... 376
21 -9.250[GE] KOG2575 Glucosyltransferase - Alg6p  ali follow..  9  33....LTHKGTTTSFLCISLFALLIRSAVTMYPYSGPPKFGDFEAQR------------------------------HW-IDWYRNGTYNDLTY--GLDYPPLTAYQSYIHGIFLRFFNPESVALLSSLMRWTVLSSDAFIFFPAALFFVLVYHRNRTKSEVAWHIAMILLNPCLILIDHGHFQCISLGLTVGAIAAVLCESEVLTCVLFSLALSHKQMSAYFAPAFFSHLLGKCLRRKSPILSVIKLGIAVIVTFVIFWWPYVHSL----------------DDFLMVLSRLAPFERGIYEDYVANFWCT-YLFSFQVHEKSILMPFLSATLLA.............................................................................................................................................................. 395
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 1 0 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;