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Query: [O] KOG2884 26S proteasome regulatory complex, subunit RPN10/PSMD4, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLITLANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGPSLADALISSPILAGEGGAMLGLGASDFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAGIATTGTEDSDDALLKMTISQQEFGRTGLPDLSSMTEEEQIAYAMQMSLQGAEFGQAESADIDASSAMDTSEPAKEEDDYDVMQDPEFLQSVLENLPGVDPNNEAIRNAMGSLASQATKDGKKDKKEEDKKLast
1 -131.000[O] KOG2884 26S proteasome regulatory complex, subunit RPN10/PSMD4  ali  100  1MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLITLANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGPSLADALISSPILAGEGGAMLGLGASDFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAGIATTGTEDSDDALLKMTISQQEFGRTGLPDLSSMTEEEQIAYAMQMSLQGAEFGQAESADIDASSAMDTSEPAKEEDDYDVMQDPEFLQSVLENLPGVDPNNEAIRNAMGSLASQATKDGKKDKKEEDKK 377
2 -77.900[O] COG5148 26S proteasome regulatory complex, subunit RPN10/PSMD4  ali follow..  47  1MVLEATVLVIDNSEYSRNGDFPRTRFEAQIDSVEFIFQAKRNSNPENTVGLISGAGANRVLSTFTAEFGKILAGLHDTQIEGKLHMATALQIAQLTLKHRQNKVQHQRIVAFVCSPISDSRDELIRLAKTLKKNNVAVDIINFGEIEQNTELLDEFIAAVNNPQEETSHLLTVTPPRLLYENIASSPIILEEGSSGMGAFGGSMDFGVDPSMDPELAMALRLSMEEEQQRQERLRQQQQQQDQPEQSEQPEQHQDK......................................................................................................................... 268
3 -36.200[KL] COG5151 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1  ali follow..  16  85.IIRHMVLVLDLSNSMEERDFHHKRFDLQIKYASEFVLEFFEQNPISQLSIIGVMDGAHRITDLHGNPQSHIQKLKSLDCSGNFSLQNALEMARASLSHIASHG-TREVLIIFGSILSSDPGDIFKTIDALVHDSIRVRIVGLAAEVAICKEICNKTNSSTKN...................................................................................................................................................................................................................... 247
4 -36.200[KL] KOG2807 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1  ali follow..  16  85.IIRHMVLVLDLSNSMEERDFHHKRFDLQIKYASEFVLEFFEQNPISQLSIIGVMDGAHRITDLHGNPQSHIQKLKSLDCSGNFSLQNALEMARASLSHIASHG-TREVLIIFGSILSSDPGDIFKTIDALVHDSIRVRIVGLAAEVAICKEICNKTNSSTKN...................................................................................................................................................................................................................... 247
5 -25.800[KL] KOG2487 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB4  ali follow..  10  22.TPSLLVVILDANPASWYSLSKKVPVSKVLADITVFLNAHLAFHHDNRVAVLASHSDKVEYLLVLSGMKRLMSSTDKVSRKTMISGALSRALAYINQVQNKNTLRSRILIFSLTGDVALQYIPTMNCIFCAQKKNIPINVCNIEGGTLFLEQAADATGGIYLKVDNPKGLLQYLMMSLFPDQNLRKHL............................................................................................................................................................................................. 238
6 -18.900[KL] COG5242 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB4  ali follow..  9  22.SPSLLTVIIEIATTFDEEGNEKGSIIKVLEALIVFLNAHLAFNSANKVAVIAAYSQGIKYLYPESTSETLVEEIYKLTLAGAMSAGLTYVNRISKESVTTSLKSRLLVLTCGSGSSKDEIFQIMNCIFSATKMKCPIDVVKIGKESTFLQQTTDATNGVYLHVESTEGLIQYLATAMFIDPSLRPII............................................................................................................................................................................................. 262
7 -18.700[R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain  ali follow..  12  40....NLSLVIDRSGSMAG-----AALHHALKAAESVVDQL---EPKDILSVVVYDDAVDTVVPPQTDKPALKKSIRQVRAGGITNLSGGWLKGCEYVKHQLDPQKINRVLLLTDGHANQDPKILTATSTQKAEEGITTTTLGFAQNEDLLIGMARAANGNFYFIQSIDEAAEVFSIEELADGITLVDTLSLAKVSQNEAGQPVITLG---ELYEGEDKLLGLSLMISSAQVGELPLMRLHYSADVVQNDIIQSVSGTTDVITKVGTVEESALASSSHIILDLSRLTIAKAKETALELAEHGQHQAAEKTLRDLVQYLRDQGLNENFEIAEEIDQLEYFAGRIAQQALGNAGRKELRDQSYQTMTRNRGDLAGRGVT. 423
8 -16.200[R] COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain  ali follow..  13  1MRRLPIFFVLDCSESMIG-----ENLKKMNDGLQMIINDLKKDPETAWISVIAFAGVAKTIVPLVE---VVSFYPPRLPIGGGTSLGAALQELTRQIDTQVRKTTEERVYLLTDGRPTDDTTAEITRWKTHYARKVNLIAIGLGPSAD..................................................................................................................................................................................................................................... 150
9 -15.900[H] COG1240 Mg-chelatase subunit ChlD  ali follow..  18  155.....VVFVVDASGSMAL-----NRMQSAKGAVMQLLTEAYQNR--DQVALIPFRGEAEVLLPPTRSIALARNRLERLPCGGGSPLAHGLTQAVRVGVNAQMGGDIGQVVIVAITDGRGN-AELLDIAARIRALGMQLLVIDTESKFVSTGFAKELAKTSGGK...................................................................................................................................................................................................................... 325
10 -15.500[R] KOG3768 DEAD box RNA helicase  ali follow..  12  1..MPILLFLIDTSASMNQRSHLTTYLDTAKGAVETFMKLRARDSRGDRYMLVTFEEPPYIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLRLFALVLRLDDSAITPMCEVTGGRSYSVCSPRMLNQC............................................................................................................................................................................................................ 219
11 -13.900[L] KOG2327 DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen)  ali follow..  16  36...DSLIFLVDASKAMFESEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGKNIYVLQELDNPGAKRILELDQFGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFL.......................................................................................................................................................................................................................................... 200
12 -13.900[L] KOG2326 DNA-binding subunit of a DNA-dependent protein kinase (Ku80 autoantigen)  ali follow..  10  1MS-ECTVFVLDLGKDMGTHGRSHSDLEWTLSYFHDELHKFLANRKTDVVGIVGYKCDDT-IQTALFSKLQSVSQTLKPSNTMQGDLISAIVVSFDLMRHCKKNKWKKKMIVLTAARGIIDFSDYIGIAEQLLQHDVFLGVYGVDFDQEDINYSEPLKESQKKENEVRIQEFVESCHGTFQQIYNNIGKPWVRKVRPVAIFRGTFSIGNRDSKDTSISIQVERTRLTKPPTSSAFYENDMSKNYECLNIENSNVENKSMESDAVSTVRSYMVRDPKTNDSFEVKREDLESGYSYGRTIVPISRSDEDVLALDTIPGYE---PKDDFESKLNFSAFVQSLEREMPYVEPFAEDVRPYFSEFEKLSNEEDMRQIDFAVSN 458
13 -13.000[R] COG4867 Uncharacterized protein with a von Willebrand factor type A (vWA) domain  ali follow..  9  483....AVALLVDTSFSMVMEN----RWLPMKRTALALHHLVCTRFRSDALQIIAFGRYARTVTAAE-------LTGLAGVYEQGTNLHHALALAGRHLRR--HAGAQPVVLVVTDGEPTAH-AHTVRGFDDMARLGAQVTIFRLGSDPGLARFIDQVARRVQGR...................................................................................................................................................................................................................... 649
14 -9.530[S] COG2718 Uncharacterized conserved protein  ali follow..  12  250.....MFCLMDVSGSMDQA-----TKDMAKRFYILLYLFLSRTYKNVDVVYIRHHTQAKEVDE---------QEFFYSQETGGTIVSSALKLMDEVVQERYNPAQWNIYAAQA-SDGDNWADDSPLCHELLAKK--VVRYYSYIE........................................................................................................................................................................................................................................ 375
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 9 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Jaroszewski L, Li W, Godzik A. A segment alignment approach to protein comparison. Bioinformatics. 2003 Apr 12;19(6):742-9.