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Query: [S] KOG2889 Predicted PRP38-like splicing factor, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MANRTEKAAKTVKGTNPQFLVEKIIRQRIYDSMYWKEHCFALTAELVVDKGMDLRYIGGIYAGNIKPTPFLCLALKMLQIQPDKDIVLEFIQQEEFKYIRALGAMYLRLTFDSTEIYKYLEPLYNDFRKLRYMNKMGRFEAIYMDDFIDNLLREDRYCDIQLPRLQKRWALEEVDMLPSYKSLLDGDLVAMSDSDSEEEEVTKKEKPRLTSRRRSRSRDRERDVGDRREVREREKLKERRERGDDEPGPSSSGSGRRDDRDDRRRDRDRSRDRDRRDRRDDDRRDKKKESRRGGADNDEEREIAEANALRAKLGLAPLERLast
1 -78.400[S] KOG2889 Predicted PRP38-like splicing factor  ali  100  1MANRTEKAAKTVKGTNPQFLVEKIIRQRIYDSMYWKEHCFALTAELVVDKGMDLRYIGGIYAGNIKPTPFLCLALKMLQIQPDKDIVLEFIQQEEFKYIRALGAMYLRLTFDSTEIYKYLEPLYNDFRKLRYMNKMGRFEAIYMDDFIDNLLREDRYCDIQLPRLQKRWALEEVDMLPSYKSLLDGDLVAMSDSDSEEEEVTKKEKPRLTSRRRSRSRDRERDVGDRREVREREKLKERRERGDDEPGPSSSGSGRRDDRDDRRRDRDRSRDRDRRDRRDDDRRDKKKESRRGGADNDEEREIAEANALRAKLGLAPLER 320
2 -56.400[R] KOG2888 Putative RNA binding protein  ali follow..  15  16.KAGKQHNTLPFWGNESSMNLNALILANIQSSSYFKVHLFKLKHEVVDEIYYQVKHMEPWERGSRKVSTAYCLLYKLYTLRLTRKQINGLLNHTDSAYIRALGFMYLRYTQPPGDLYDWYEDYLQDEEEIDVKA--GGGQVLTIGQMVYQFMTKLDWFSTLFPRIPVPIQKQIEKRIEQYGGRGGGQAGSRSNAYPQPNNYRNDYDERDYYAAASGSSYGRGRGGYEDYPPAPLPPQMPYGERERERDRDRDKNKDYDRHRSKHKKKHNHRQSSRSRSRSRSRSRHRSERHERKRDGGGYERSSKSRHNEHYEERERRHR 398
3 -17.900[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  14  508.........................................................................................................................................................QDTLHGIEAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDT 674
4 -14.900[S] KOG4610 Uncharacterized conserved protein  ali follow..  9  316............................................................................................................................AEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSS 511
5 -14.200[A] KOG2217 U4/U6.U5 snRNP associated protein  ali follow..  13  46...................................................................................................................................................................RHRHHKHKKHKEHRHKHHKQKERERANEVISLEESDSDSSDCVEVPVQAQVQAQAKLRDARESSNRDKERDSGRDRELLRERERERDRERERDRDREKEREREREKERLREREREREREKERIREREKERLRERERERERERVRELTAPPPPQISKH 203
6 -13.600[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  12  281.....................................................................................................................................................................SRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSE 435
7 -12.800[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  13  158........................................................................................................................................................................................EENNCNRGGYCNFMHVKLVSRELRRKLFGRYRRSYRRGSRSRSRSRSISPRNKRDNDRRDPSHREFSHRDRDREFYRHGSGKRSSERSERQERDGSRGRRQASPKRGGSPGGGREGSEERRARIEQWNREREEKEE 293
8 -12.800[Z] KOG3809 Microtubule-binding protein MIP-T3  ali follow..  12  148.....................................................................................................................................................................ELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKP 302
9 -12.100[K] KOG2478 Putative RNA polymerase II regulator  ali follow..  10  381.........................................................................................................................................................................EEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
10 -11.800[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  10  1................................................................................................................................................................MLPFVFNADDDGKRVQNEEGNYDPTDHQRQMEDYYKQYEEQRQVANSFHNTTGRPDLVAMQARLAETEQAIHRLNEEKKQPPPGFPIMTTPATQPEISIPRSGENKSSRSPSWAREARRSRSRSRDRRGGRSRSRSPSRRRTSRDRRDDRSSRRRRDRSH 160
11 -11.800[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  15  253.........................................................................................................................................................................AERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDREREKKKKRSKSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEK 403
12 -11.500[T] KOG1882 Transcriptional regulator SNIP1, contains FHA domain  ali follow..  7  1....................................................................................................................................................................MKAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNER 156
13 -11.000[A] KOG2253 U1 snRNP complex, subunit SNU71 and related PWI-motif proteins  ali follow..  14  82..................................................................................................................................................................DREAKNRPEASKRSRRSRSSSNSSSESDSSSSRSSSYSSRSRSRTPQRSRTSKRRRSNSHASEDSDDAREKRAFKQMMLDKKQAYLARLKRWESRERQMSKRYEREERKEKDRKKTLQKEGKRLKLFLEDYDDEKDDPKYYTSSQFFQRKRDYERERE 239
14 -11.000[R] KOG3263 Nucleic acid binding protein  ali follow..  10  3.........................................................................................................................................................................SSRSGEHRRNYAQGRNYESSRSRGDQRDRDYREYRRNYRDERSSRRYEDSQRRDYSPARRRDRYERHRESVREESPRRPVEHERNWQPELKHGRERFRERDYEGRRDRKERRDGVSPFSPEGEGLERKREHEKLQAPSPKEEEERPVDQGD 153
15 -11.000[A] KOG0796 Spliceosome subunit  ali follow..  12  258.................................................................................................................................................................................................DSDRRLADHFGGKLHLGYMLIRDKLAELQEEKNKVHKERVEERRSKERSRERESSKDRDGGDNRDRGRDVDRRSRDRDRHHDHREHDRNYNQSRGDSRSRRSSRSRSRERPRDHDRRRRHDR..... 380
16 -10.900[R] KOG4520 Predicted coiled-coil protein  ali follow..  7  131........................................................................................................................................................................................VAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEHRRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGSE.... 262
17 -10.600[R] KOG2140 Uncharacterized conserved protein  ali follow..  11  709............................................................................................................................HSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSP 904
18 -9.820[O] KOG0314 Predicted E3 ubiquitin ligase  ali follow..  8  558..................................................................................................................................................................SRQGPPPPISSDYDRRRRSDRSSPERQSSRRFTSPPRSSSRKSERDRHHDLDSEHDRRRDRPRETDRKHRKRSEKSSSDPTVEIDDNNKSNVFTRISFPEESSGKQRKTSKSSPAPPESSVAPVSSGRRHHSRREREMVEYDSSDDEDRHFKRKPSRY 715
19 -9.730[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  19  805..............................................................................................................................................................ENEIDVEQRQKLRHIEIALIEYRESLEEQGMKNSEEIERKVAIHRKRLEADGLSGNQRVLPEKREKREDSRDSSRKRNRSESQNRSQSPPQKS-LTRERVRDHDLDKDRHRDRDRQQHDLDKDRKRRAKSSSRERD-DHDRSRERDRDWRRRGMR....... 957
20 -9.560[S] COG5291 Predicted membrane protein  ali follow..  6  127.................................................FSATITYIWTKRNPRAIVQIFGFISFPAFYL-PFILPGFMLLSRRSISIDDVLGIV-------VGHLFHYFKDVY----------PRWGRDILSTPCWVKKLFNE-----------HPSSCCKARKGITIREGRERHERNMGYSNASTTSGDSMASLTDMADTKSSTENSAVTEESQCCAESFKDSSVVSSQKSMAVSTVVGSSTEAKNNYLDFTEALCDKEVVAEQNPESQSNEEWDEKWGDSDNESECS.................... 348
21 -9.530[S] COG3371 Predicted membrane protein  ali follow..  13  1.........MRIFGLGPIIALAGVVFAYLLNRDWWS-----ITENAISDLGRVGLPNNWVMNCGLIIGGLLLLGYGAWRLKKSKNPGWAIY---------VVGSVFLVLIG................................................................................................................................................................................................................. 89
22 -9.020[K] KOG4501 Transcription coactivator complex, P100 component  ali follow..  11  453..............................................................................DIDLEVTAVLEVLPDLGSGFIRRL----LIRYDNSEQVIAAIHFNVHDGDRYDVLTRDQGKGLPGAPRNAEQLLDDKRDLKQLKERYQKYAMVEETTLERGEYDDEYDDSYEAQNEGQAPPVSLLRGRLQEAASSSAYNAQDELENDDEESSGGHSDPEPSMRTNRDFCENPEVIRARYEQRQLSKYGQKSGGHGASPSVVGAPKGQGQSQQTQRSRGQKEAHKSTRANHNRKAGAAFKRSK 731
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 3 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;