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Query: [S] KOG2946 Uncharacterized conserved protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFEDVNTSPSLEGDMSIPGKRTTTATSASGVPEYNTLDEPIRETVLRDIRAVGIKFYHVLYPKEKSSLLRDWDLWGPLVLCTFMATILQGSSTADSMSDNGPEFAQVFVIVWIGAAVVTLNSKLLGGNISFFQSVCVLGYCLTPVAISLIVCRVILLATQTRLLFFLRFVTTTIGFAWATYASFVFLGQSQPPHRKPLAVYPIFLFFFIISWLVLSHNLast
1 -106.000[S] KOG2946 Uncharacterized conserved protein  ali  100  1MFEDVNTSPSLEGDMSIPGKRTTTATSASGVPEYNTLDEPIRETVLRDIRAVGIKFYHVLYPKEKSSLLRDWDLWGPLVLCTFMATILQGSSTADSMSDNGPEFAQVFVIVWIGAAVVTLNSKLLGGNISFFQSVCVLGYCLTPVAISLIVCRVILLATQTRLLFFLRFVTTTIGFAWATYASFVFLGQSQPPHRKPLAVYPIFLFFFIISWLVLSHN 218
2 -80.600[U] COG5080 Rab GTPase interacting factor, Golgi membrane protein  ali follow..  19  23...FNTQSRAAGFYDEPLHEPLSQGWLAAFSTSGYPGEPSLLEELEINFGHIKQKTTHVLNPFKDVHIMDDTDMAGPILFCLLFSTFLSLH--------GRSHFGYIYGIALLGSLSLHFVLRLMSKNLFFTRTVSVLGYSLLPLVVIAFFKNIFTF------NGIAGYALAALACIWCTYAASAMFGILQVNNMRFLVAYPIALFYGVFAVITVFSK 227
3 -70.300[U] KOG3103 Rab GTPase interacting factor, Golgi membrane protein  ali follow..  19  60..LGGFYDPTAYTDTSYGQDKSGKSAAGGGAGNEFDDEPPLLEELGINPNHIFQKTLAVLNPLRDQQILQDTDMAGPLVFCLTLGGFLLLS--------GKVTFSYIYGIGVMGCIFFYCLLSLMRSQVTFGAVASVLGYCLLPMVVLSGINILITIQG------TLGLIVSGISIFWCAISASKLFTAFSMDHQQLLIAYPCAVLYGGFALITIY.. 264
4 -25.000[S] KOG3114 Uncharacterized conserved protein  ali follow..  18  109............................................FDVDTSDVVERLKESLFPFRGEKTANNPDLYGPFWICTTLIFVAASIGTFVTYIAHTWSAGVFYGYVTIVPLALYVVLKYFSAPSGLVQLFCLYGYSLFVFIPALCLSVVP--------LEIFRWVIAGLAGFMSATFVALNLKAHSAGERWFLIVVSIFLLQLALSVVLKL.. 291
5 -17.100[S] COG5197 Predicted membrane protein  ali follow..  13  67...AFQLGQSAFSNFIGQDNFNQFQETVNKATANAAGSQQISTYFQVSTRYVINKLKLILVPFPPRDDVNSPDMYMPIMGLVTYILIWNTQQGLKGSFNPEDKLSSTLAFVCLDLLILKLGLYLLIPSFSLVELLCYVGYKFVPLILAQLLTNVTM-----------PFNLNILIKFYLFIAFGVFLKSTVKKCNYFLFVYGFIWQNVLMWLMG.... 314
6 -16.900[S] KOG3094 Predicted membrane protein  ali follow..  15  55........................................PQYYFQVNDQYVRNKLKIVLLPFLHRG-INAPDLYIPLMAFGTYVVLAGLSLGLYGKFTPEWLFVKGMVGWFLQVMLLKITLLSLGGEAPLLDIVAYAGYTFTGLCLAVLGKIIWGY-------------SYYVLIPWTCLCTGVFLRSYDSSRHHYLLIFVALAQFPLLIWLG.... 251
7 -13.600[S] COG2881 Uncharacterized protein conserved in archaea  ali follow..  15  27.....................................................................................................STFLGFFATWLIIAAVMHGLSAFFDGRGEFRRTFEFAGYGFMLSLLGSAVTIPVSLKYVEEAYVYSAIFLNLAVTAWSFLIALKNARNVELKQAAVCAAIPTAIVYQVMALVRLLQ. 175
8 -10.200[S] KOG3012 Uncharacterized conserved protein  ali follow..  11  55........................................LLKFNQMDFEALWQMLYLFVAPQKRKQTKSQFARDDPAFLVLLVVCLCVTSLGFAYVLGLS--FWQSISFIFYVVFVDCIFVGIIIASFFWAVTNRYLGYAFFPPLMLLHFIQLFFYNWLISQTWFISRFLGLMGMGYYVYITFLGYNCIPHLKNTRIILIALPIIFLLFLVVTIIG. 259
9 -9.090[O] COG5264 Vacuolar transporter chaperone  ali follow..  15  118............................................................................................................................VEAKVWLANERTFLKWLHVVVLLGSLALALYNSAG-ERLGQAFGVVYTLLAIFIGFYAWKLHAKRSQMIKSRSPAPMPLIVGTALAISLIV... 212
10 -8.880[R] COG1272 Predicted membrane protein, hemolysin III homolog  ali follow..  10  44.............................................................................VVFGIVGLVLLLVQAVNSGADTKALTSYSLYGSSIILLFLASTLYHAIPHR-RAKLWLQKFDHCAIYILIAGTYTPFLLVGLDSPLA------RGLMAVIWGLALIGVIFKLAFAHRFEVLSL----VTYLTMGWLSLI.. 171
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li Z, Ye Y, Godzik A. Flexible Structural Neighborhood--a database of protein structural similarities and alignments. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D277-80.