current user: public

If you have questions about the server, please let us know.

Query: [I] KOG3006 Transthyretin and related proteins, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320
# Score Template Links and tools%idFirst MAMEIGEDEWKVCCGSSEFAKQMSTSGPLTSQEAIYTARDIWFNQVNVTDWLEAFSAHPQIGNTPSPSINSDFARRSVSEQSTAFATTSASALQELAEWNVLYKKKFGFIFIICASGRTHAEMLHALKERYENRPIVELEIAAMEQMKITELRMAKLFSDKAKVISETDSSSSPVSTKPQDRLRIIGGHLNVAAEAKAPKRSRPPITTHVLDVSRGAPAAGVEVHLEVWSGTTGPSFVHGGGGVWSSVGTSATDRDGRSGPLMDLVDALNPGTYRISFDTAKYSPGCFFPYVSIVFQVTESQKWEHFHVPLLLAPFSFSTYRGSLast
1 -134.000[I] KOG3006 Transthyretin and related proteins  ali  100  1MAMEIGEDEWKVCCGSSEFAKQMSTSGPLTSQEAIYTARDIWFNQVNVTDWLEAFSAHPQIGNTPSPSINSDFARRSVSEQSTAFATTSASALQELAEWNVLYKKKFGFIFIICASGRTHAEMLHALKERYENRPIVELEIAAMEQMKITELRMAKLFSDKAKVISETDSSSSPVSTKPQDRLRIIGGHLNVAAEAKAPKRSRPPITTHVLDVSRGAPAAGVEVHLEVWSGTTGPSFVHGGGGVWSSVGTSATDRDGRSGPLMDLVDALNPGTYRISFDTAKYSPGCFFPYVSIVFQVTESQKWEHFHVPLLLAPFSFSTYRGS 324
2 -62.200[S] COG3195 Uncharacterized protein conserved in bacteria  ali follow..  20  3.ERDDFIRRFGGIEHSPWVAERAYDRAASSGAGNVHSALCNAFRAASPAERLRVLRAHPDLAGKLAVAGELT-ADSKAEQASAGLDRLSPEEHSRFTGLNTTYTKKFGFPFIIAVKGLTKEDILAAFERRIDNSKEEEFETACAEVERIARLRLRSMLPGDDNA................................................................................................................................................................ 167
3 -51.800[R] COG2351 Transthyretin-like protein  ali follow..  32  1..........................................................................................................................................................................................................MGRLTTHVLDTAAGTPGKDLAITLFKIVN-----------NLRQPIKTVRTNHDGRCEAPLLEGEALQAGIYELDFAVGDYYRAAFLDVVTLRFGVADAG--AHYHVPLLVSPWSYSTYRGS 117
4 -5.810[O] KOG1730 Thioredoxin-like protein  ali follow..  12  73....................EELLFNIPFTGNVKLKGIIIMGEDDDSHPSEMRLYKNIPQMSFDDTEREPDQTFSLNRDLTGELEYATKISRFSNVYHLSIHISKNFG-VFYIGLRGERRHEVTICNYEASANPADHRVHQVTPQTHFIS.............................................................................................................................................................................. 210
5 -5.600[O] KOG0691 Molecular chaperone (DnaJ superfamily)  ali follow..  11  1......................MVKETEFYDVLGVSPTATE--AEIKKAYYIKARQVHPD------KNPNDPQAAHNFQARRTPLSLVEFLGFLAYDVLGEAY------------------QVLSDPGQRQAYDT............................................................................................................................................................................................. 87
6 -5.430[S] COG3159 Uncharacterized protein conserved in bacteria  ali follow..  1...............................MKQPGEELQETLTELDDRAVVDYLIKNPEF-----IRNARAVEAIRVPHPVRGTVSLVEWHMARARNHIHVLEENMALLMEQAIANEGLFYRLLYLQRSLTAASSDDMLMRFHRWARDLGLAGASLR...................................................................................................................................................................... 124
7 -5.410[S] COG3253 Uncharacterized conserved protein  ali follow..  11  158...........................PMDKRRQ-----DDNWYMLPMDQRRELMKSHGMIGRSYAGKVKQIITGSVGFDDWEWGVTLFADDVLQFKKLVSARYGEFG-SFFVGNL-LTAEGIPSYFY.................................................................................................................................................................................................... 260
8 -5.220[S] COG3310 Uncharacterized protein conserved in bacteria  ali follow..  91............................FDVFNDMLDIADAAVVENGLEGIVQIAPFHPD---QFEGTDSDDIGNYTNRSPYPTLHLIREDSIAKIFERNIALLEKMGHEGW--------AKLGITSCPYPHNKKNIS.......................................................................................................................................................................................... 200
9 -5.170[S] COG2237 Predicted membrane protein  ali follow..  37..RGDMQTLVICIDRDNDLGEKAKMETPIVGREANVRAAVALGIADPEDSDTNTIFGGIRILDELLEKGVDAEIVSFAGDKNVGV-ISDQKIAEQLELYLQMNEVK----AVFVSDGAEDETLVPIVQSRMKIDSVKRIVVMQSENLESTYYILKHVFSDPK.................................................................................................................................................................. 192
10 -5.150[I] COG1443 Isopentenyldiphosphate isomerase  ali follow..  10  40............................FNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRC------RYELGVEITPPESI-RATDPSGIVENEVCPVFAARTTSANDDEVLADVLHGIDATPWA........................................................................................................................................................................................... 157

FFAS is supported by the NIH grant R01-GM087218-01
1 4 3 0 4 3   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhang Y, Stec B, Godzik A. Between order and disorder in protein structures: analysis of "dual personality" fragments in proteins. Structure. 2007 Sep;15(9):1141-7.