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Query: [F] KOG3079 Uridylate kinase/adenylate kinase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEGLast
1 -95.500[F] KOG3079 Uridylate kinase/adenylate kinase  ali  100  1MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG 228
2 -73.100[F] COG0563 Adenylate kinase and related kinases  ali follow..  29  1...................................MNLILMGLPGAGKGTQAEKIIEKYGIPHISTGDMFRAAMKN-ETELGLKAKSYMDAGELVPDEVTIGIVRDRLSQDDC----QNGFLLDGFPRTVAQAEALEDILASDKKLDYVINIDVPEQLLMDRLTGRSELIQRDDDKPETVKKRLEVNQKQAQPLIDFYSEKGYLQNINGDQDISRVFEDINELLKG.. 214
3 -72.700[F] KOG3078 Adenylate kinase  ali follow..  31  1....................MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVA-SGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLC----KNGFLLDGFPRTVRQAEMLDDLMEKKEKLDSVIEFSIPDSLLIRRITGREPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK.. 229
4 -33.500[F] COG2019 Archaeal adenylate kinase  ali follow..  13  1...................................MRSVITGVAGVGKTTVLDIVARESGIPVVNYGTLMFEVAKRRG------LVENRDQIRKLSRETQVDLQKLAGEEI----GKMENAIVDTHMSIKTPFGYLPGLVLRSINASVFVIIEADPAIIKRRRDND-PTRARDDEGVDSIREHQEMNRYFAAAYSIFSGATVKIVK-NEEGKPEQAADEIVRVIK... 181
5 -22.700[G] COG2074 2-phosphoglycerate kinase  ali follow..  11  87..............................QCKEPLIILIGGASGVGTSSIAFEVANRLGIRNMISTDMIREVMRKIVSRPPPPELDEVLIGFRDHVESVSIGVEAVIERAL---TEGISIVIEGV-----VPGFIREDLVNKENVAMFVLTVSDENVHKGRFYSRCRQMW-ARRPLKRYISYFWAIRRIHRYIENQARKHGVIENIDVVTTIDSIIKSLTKTTVK.. 296
6 -21.800[F] COG1936 Predicted nucleotide kinase (related to CMP and AMP kinases)  ali follow..  18  1...................................MLIAITGTPGVGKTTVAKLLAKKLNYEYVSLKDFALEKGCGRRVN-------------------EVEVEIDELAYFIERELKGKNAVLDGH-------------LSHLMPVDLVVVLRAHPKLIGERLRERGYDREKIGENVEA-----ELVDAVLIEAIEEHENVIEVDT--TNKSPEDVVEEIVSLINS.. 153
7 -21.500[R] COG0645 Predicted kinase  ali follow..  14  2...................................FLAVTHGVSAVGKSQVAMRLVEALGAVRLRS-DIERKRLFGEQPEHD---RGQFAAG-IYSSQASEATYAHLHQLAAKILQAGYPVVIDAAYLKQNQRQAACHIAEETGVPFLILDCQAPEAVIAGWLAQRQAEGKDPSDATLDV---IRTQQATREPLTAAETVQSKRVDTHDAASLDGLVDGIRQRLPG.. 184
8 -21.300[F] KOG3347 Predicted nucleotide kinase/nuclear protein involved oxidative stress response  ali follow..  17  1................................MLLPNILLTGTPGVGKTTLGKELASKSGLKYINVGDLAREEQLYDGYDEEYDCP------------------EDRVVDELDNQMREGGVIVDYHGCDFFPERWFH----------IVFVLRTDTNVLYERLETRGYNEKKLTDNIQC-----EIFQVLYEEATASYKEEIVHQL--PSNKPEELENNVDQILK... 161
9 -19.300[R] COG4639 Predicted kinase  ali follow..  14  4..............................TIPELSLVVLIGASGAGKSTFARKHFQPF--EVISS-DFCRGLVSNDENSQSASRDAF---------DVLHYITTKRLAA-------GKLTVIDATNVQPEDRKTLLQMAKQYHCFTVAIVFDLPEELCHERNQQRSDRQ-----GSHVVRRHTQMLRRSLRSLEK--EGFRYVYTLKSPEEIANVAIELQPLWNNK. 175
10 -18.400[G] COG3265 Gluconate kinase  ali follow..  14  1................................MSGKCIIVMGVSGTGKSCVGQALALALGAKFIDGDDLHPRANIQK-----------MAAGQPLNDQDRAPWLERLSDVAYSLQQKNEVGFL----VCSALKKQYRDRLREGNEGIRFLWLTGDYDLVLHRMQQRAG-------PESLLKSQFATLEAP-------GSDEPDVIPIDISSSIADVVEHCIAALSLE. 169
11 -18.200[S] COG4185 Uncharacterized protein conserved in bacteria  ali follow..  12  7.............................KKLEQPVFLIVAGPNGSGKSSVYANADLELSVWIVNP-DLLAGRISEVENKPLPEANLVAVQ-------RIEAWIQSSISV-------HKTIGVETVLSTDKYRRLVEAAEAVGFAIWLFYTVLDSPERSIERIKLRVAKGGHD--PADKVRAR---YARSLDQLPWFLERADRAWIWDNSGATPKLIGEKQD...... 183
12 -18.000[V] COG3896 Chloramphenicol 3-O-phosphotransferase  ali follow..  12  16...........................AMAGMPEGKLILLNGGSSAGKTSLALAFQDLAAECWMHIGDLFWFALPPEQLDLARVRPEYYTWDSAVEADILDLAMHSRYRAIRAYLDNGMNVIADDVIWTREWLVDALRVFEGCR---WMVGVHVSDEEGARRELERG------DRHPGWNRGSARAAHADAE------------FELDTTAPVHELARELHESYQACP 211
13 -17.900[F] COG1102 Cytidylate kinase  ali follow..  17  3................................KGCLVITVSGLAGSGTTTLCRNLAKHYGFKHVYAGLIFRQMAKERG----------MSLEEFQKYAELHPEIDREVDRRQVEAAKECNVVIEG------------------KNADLKIWLDAPIRVRAERVAKREEAFMKIAEREMQNRKRYLNLYGIDINDLSIYDLIIDTSKWSPEGVFAIVKAAIDHLYEK.. 180
14 -17.500[G] KOG3354 Gluconate kinase  ali follow..  13  7...........................NPTNQPYKYVFVVIGPAGSGKTTMAKAVSEKLGFEYIEGDDLHPKANIEK-----------MSQGHPLNDN--LHNCGGACAMELDKESIKGVVLTCSALKRSYR-DILRSSLEHRPAILRFIYLAASRETLIKRTTSRKN-------KADMVESQLAILEAPT-------ADEKDVITISVENGKEQSEEECLDIVHK.. 185
15 -17.300[P] COG3709 Uncharacterized component of phosphonate metabolism  ali follow..  11  1....................MTTGGEDSRRTLSPGTMIVIVGPSGAGKDTLMDYAAAQLS-FHFTRRVITRSCDAGGENHD-HEFNQLEDAGAFAVSWQAHGLKYGIPAAVYRHLEAGDVVIANGSRSALPHFGTAFSRL-------KVVNIVARPDVLARRLEQRGR------ESRDDILRRLERSSLAVAGDFDV-------TTVDNSGAIEDAGKTIMQVLQQS. 193
16 -17.000[F] COG0125 Thymidylate kinase  ali follow..  17  1................................MSGLFITFEGPEGAGKTTVLQEIKNILT----AEGLQVMATREPGGIDIAEQIREVILNENNILMDPKTEALRQHLVEKVKPALEQGFIVLQGYARGLDEVLSINEFAIGDMMPHVTVYFSIDPEEGLKRIYANGREKNRLDLEKLDFHTKVQEGYQELMK-----RFPERFHSVDAGQSKDLVVQDVLKVIDEA. 206
17 -16.000[F] COG0283 Cytidylate kinase  ali follow..  16  1...............................MNRQKVIAIDGPGASGKGTVAARVAAALGYDYLDTGALYRLSELAKKLPAVFSDSRILLGGEDVSDGIQLPKVRASLLQRQRDFLTEKGLVADGFP-----------------QAELKIFLTAESKIRAERRAKQIGIPCEGLAFERILSDIEARDEADRNRKVAPLKQQPDALLLDTSRTIEETVKKVLDWYRK.. 217
18 -15.700[F] COG1428 Deoxynucleoside kinases  ali follow..  10  2..............................EGVGNKVIVLAGMIGAGKSSYTELIANELGTKAFY-------ESIKDNRILEMFYDDPKRWAFALQIYFLNTRFRSIKAALTDQNNVLDRSIYEDA-LDLLDNMMEELAYMPKKAPDLLIYLRGSLDTVLSRISLRGRPYEQTFDNPGLLD--YKHLHSRYDSWFESYDKSDTLV-INIDSDAKYVMQLIHEKLKR.. 214
19 -14.900[L] KOG2134 Polynucleotide kinase 3` phosphatase  ali follow..  16  1.....................QTSPESIEADKAKQIVVLLIGPPGSGKSTFCDTAMRSSHRPWSRICDIVNNGKAGTKAQCLKMATDSLREGKSV--------------------------FIDRCNLDREQRSEFIKLGGPEFEV-HAVVLELPAQVCISRSVKRTEGNLQGGRAAAVVNKMLQSKELPKVN-----EGFSRIMFCYSDADVDNAVNMYNKL..... 173
20 -14.800[E] COG0703 Shikimate kinase  ali follow..  14  37AISYEVSVHVLRSSLSEAGLSLTNSLSSTEKMAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTGADVGWV------FDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGV------------VVYLETTIEKQLARTQRDKKR-----HVETPPREVLEALANERNPL---YEEIADVTIRTDDQSAKVVANQIIHMLESN. 240
21 -14.800[FH] KOG2702 Predicted panthothenate kinase/uridine kinase-related protein  ali follow..  16  123..............................SPNLKRLVGLAGPPGAGKSTVANEVVRRVN--HLYRSQL-KEAHARRGAPWTFDPALLLKNEGSVYVPSFDHGVGDPVEDDIFVSLQHKVVIVEG----LLEEGSWKDISD----FDEKWFIDVNLDTAMQRVENRHISTGK---PPDVAKWRVDYNDRPNAELIIKSKTNADLL....................... 327
22 -14.600[C] KOG3877 NADH:ubiquinone oxidoreductase, NDUFA10/42kDa subunit  ali follow..  11  80................................ENSKVICVEGPIAAGKSKFAKELAEELDMEYYPAYDMRKLDPQLPPSCRSYDVRNFCLDPS-FQIRMYMLRYSQYIDALQHVLSTGQGVVLE-FMEAMFRQELRQNTIGELLKPHLVIYLDLPVDAVKKQIKARNVDYEVQSKSDAYLSDLEQLYKQ----YLKDISTHAELLIYDWTAETEVVVEDIERIDFNQ. 311
23 -14.300[F] COG4088 Predicted nucleotide kinase  ali follow..  14  3....................................LIIVSGYPSSGKTTRSNELKKALEDRIHQN-KDYRVIIINDESLNIEKETYRESKNEKAARGLLYSAVQRELSK-------STFVICDALNYIKGFRYQLYCESKSMYTTHCVIHVAVPQDLCRKFNSNKEQPY--PDDVLEQLMFRY----EEPNGMTRWDSPLFTVLHDDASCPIDDIWSVLIH...... 178
24 -13.300[F] COG0194 Guanylate kinase  ali follow..  15  43................................ERGLLIVLSGPSGVGKGTVRQAIFSQED-FEYSISVTTRS--PREGEVNGDEFEQMIADNKLLEAEYVGNYYGTPVDYVEQTLQDGKDVFLE-------EVQGALQVRNAFPEGLFIFLAPPSLSELKNRIVTRGT------ETDALIENRMKAAKAEIEMMDAY---------VVENDNVETACDKIKAIVLAE. 226
25 -13.100[H] COG1072 Panthothenate kinase  ali follow..  11  74............................TNGQRIPYIISIAGSVAVGKSTTARVLQALLS--LHPNQVLKERGLMKK-HRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLGMDYPHDPHHVFVSD----VDFSIYVDAPEDLLQTWYINRFLKFREGATKEEAIKTAMTLWKEINWLILPTRERASLILTKSANHAVEEVRLR......... 307
26 -12.900[H] COG3172 Predicted ATPase/kinase involved in NAD metabolism  ali follow..  13  9...................................RTVAILGGESSGKSTLVNKLANIFNTTSAW--EYGRDYVFSHLG----------GDEIALQYSDYDKIALGHAQYIDFAVKYANKVAF--IDTDFVTTQAFCKKYEGREHPFVQALIDEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEEDYDSRFLRCVELVREMMGEQ. 186
27 -12.600[F] KOG0707 Guanylate kinase  ali follow..  17  136.................................AEKPIVISGPSGVGKGTLISMLMKEFSMFGFSVSHTTRS--PRSMEMDGKVMEKEIKDGKFLEASVHGNLYGTSIESVEAVTDSGKRCILD-------DVQGARSVRASSLDAIFIFVCPPSMKELEDRLRARGT------ETEEQIQKRLRNAEAE----IKEGISSGIFGLILYNDNLEECYKKLKVNHLL.. 320
28 -12.400[R] KOG4622 Predicted nucleotide kinase  ali follow..  13  12............................SDGPRKRGLCVLCGLPAAGKSTFARALAHRLQIGVVAYDDVMPDAFLAGARARPAPSQWKLLRQELLKYFSAAFEAQSCYLLTKTAVSRPLFLVLDDNFYYQSMRYEVYQLARKYSLGFCQLFLDCPLETCLQRNGQRPQAL--PPETIHLMGRKLE------KPNPEKNAWEHNSLTIPSPACASEASLEVTDLLLT.. 245
29 -12.000[F] COG1618 Predicted nucleotide kinase  ali follow..  15  6..............................KEKTMLRIAVTGSPGVGKSTVVAKTAEKLAEKPFKIGGIRTAEIRKEGHREGFSIRDLATGKTGILSHVNLDDLERIGANAVRNALACDLVVIDEIGPMELISQSFVSAVEEVLESDKPVLAVLHHHPLAQRFRKGFEVLTVDKGNRDELPEKITNRFLRKL.................................... 183
30 -12.000[H] KOG3220 Similar to bacterial dephospho-CoA kinase  ali follow..  17  2...................................FIVAVTGGIATGKSTISKVF-ERQGIPVIDA-DKIAREIVEPGQPCWRQIREVFGDEVLLPSK---EINRAVLGKMIFEDKELRGKLVTGHAWIVLDLPLLFETGVLMDFIHKIVCVTCDSDKQLERLIARNEL------SESEARHRV----DSQMPLDKKCEKSHFV--IDNNGSVEEAESSAMSIYNL.. 195
31 -11.900[F] KOG3327 Thymidylate kinase/adenylate kinase  ali follow..  12  4..........................................................................PERSSSIGQVINSYLTNSKDLPDEVIHLMFSEHINQVKEKLLEGTTLVVDRYSFS--DFDWCYAPERGLIKPDAVFYLRAPPNDLTHRGQYGKERY----EKVEFQGRVAEVFNRICS------KEGSYFHQFDARQSVEDLHAQIASITEE.. 157
32 -11.900[R] KOG3062 RNA polymerase II elongator associated protein  ali follow..  13  3....................................LVVITGLPASGKSTRARQLRDHFKVHLISENEAVPKAGFGKNSHTGDSQKEKVVRSDL------KSEASRHLNQEDL-------VILDAGNYIKGYRYELYCMSKVSRTTQCTVFTCIPQEEAWTFNSQRTAPDELPGDSER.................................................. 136
33 -11.500[R] COG3911 Predicted ATPase  ali follow..  16  2..............................QNDFDRVFVLTGGPGSGKTTLIAALRRA----FATSVVAGRGIVRDQSSIGGTALPW--------RTLFAELMLSWEMRSYQNAVEQKGPVFFD---RGVPETLGYLRLSGLPVADHVSTAAKRFRYNPRVFIAPPWPDIFAQDERKQTPDEAKCTYHA----LAEIYTELGYELVPLPLAPVETRLRFVLADAG... 181
34 -11.400[G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-2,6-biphosphatase  ali follow..  14  36................................NSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTGVYRREAVKSYKSY--DFFRHDNEEAMKIRKQCALVALEDVKA---LTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDENVMEDFLKRIECYKVTYRPLDPDNYDKDKVINVGQRFLVNRVQDYIQSKI.... 238
35 -11.300[C] COG3954 Phosphoribulokinase  ali follow..  13  3................................AKHPVIAVTGSSGAGTTTTSLAFRKIFAAAEVEGDSFHRYTRPEMDMAIRKARDAGRHISYFGPEANDFSLLEHTFIEYGQTGKPTDVLFYEGL-----HGGVVTPQHDVARHVDLLVGVVPIVNLEWIQKLIR-DTSERGHSREAVMDSVVRSMDDYINYITPQFSRTHINFQ...................... 206
36 -11.100[S] COG5324 Uncharacterized conserved protein  ali follow..  14  376...................ELKNAIDYDKVDERTKFLIFPISVIGCGKTTTSQTLVNLFSWGHIQNDDI--TGKDKSQLMKKSLELLSKKEIKCV--------------------------IVDRNNHQFRERKQLFEWLNELKEDYLVYDLSEIRDITLQRVIKRG-------NNHQSIKWD-ELGEKKVVGIMNGFLKR--YQPVNLDKSPDNMFDLMIEL..... 558
37 -10.800[F] KOG3308 Uncharacterized protein of the uridine kinase family  ali follow..  10  3................................RKTIIVGVSGASCSGKSTLCQLLHAIFEGSSLVHEDAFLENLHRDHGVLPTHLRNRENKNVAPEALIEYADIIKEFKAPAIPTLEQHLVFVDGF---MYVNEDLINAF------DIRLMLVTDFDTLKRRREARQDPPHYFENYVWPGYVHGHSHLFVNGDVTGKLLDKRIQLSPSSKMSVRDNVQWAINSILNA. 228
38 -10.700[H] COG0237 Dephospho-CoA kinase  ali follow..  16  2..................................TLVIGLTGGIASGKSTVANMLIEK---ITVIDADIIAKQAVEKGMPAYRQIIDEFGEDILLSNG---DIDRKKLGALVFTNEQKRLAL---HPAVRQEMLNRRDEAVANREVDKIIVVSVTKELQLERLMKRNQL------TEEEAVSRI----RSQMPLEEKTARADQV--IDNSGTLEETKRQLDEIMNS.. 195
39 -10.400[F] COG0572 Uridine kinase  ali follow..  12  2............................TDKAHQCVIIGIAGASASGKSLIASTLYRELRIGVIPEDGYYKDQSHLSMEERVKT--QALKAGKPVELPL-YSYTEHTRKKETVHLEPKKVIILEGI------LLLTDIRLRQEMNFS--IFVDTPLDICLMRRMKR-DVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIGGKNRIAIDILKAKISQFFE... 213
40 -10.300[S] COG2326 Uncharacterized conserved protein  ali follow..  13  55..............................KTGARIVIVFEGRDAAGKGGVIKRITERVSPRVFRVVALPAPTDREKTQIMQRYIQQFPAAGEVV-NRPGVERVMGFCSEKK-------------AKRFLEIAPRFEAAMIESGIVLLKYFLDVSEEEQDRRFRQRINDPLRQSPMDVESYRRWWDYTRAYDEMIRMTDTDDIVPSDNKKQARVNCIAHILSSIPYE. 252
41 -10.300[N] COG1419 Flagellar GTP-binding protein  ali follow..  16  170................................FKNAKVLFVGTTGVGKTTSLAKLAARFKIDEILTLDTYRIAA----------AEQLKIYADIMDIPMKIAYTPKEAEYEMMALKDYDIVLVDG-HQNDLQMSELRALSEAVKPNITFLVLSMNYKL-MKRIVERFSAVKPTHDETSVYGTFVNISEITGLPI--AFVTNGQIFEANPVELARIVAGEVLN...... 367
42 -10.200[R] COG4240 Predicted kinase  ali follow..  13  83.............................QQLKRPFIQGILGSQGTGKTTMSLVIQLILQTLSLSLDDLYKTYSDRL--VLLQQDPRLIWRG--PPGTHDIDLGLNVLEQIRQGKSPVI-LIFEGWDEDKAFARDMNLRLNHYLPLDSLILLYPTDYRCSLEWRKQAEQKMIAAGKTGMSNTQIEEFVNYFWRSLHPEALVDLVVEIHPDHTFGQVYQP......... 333
43 -10.200[R] KOG2878 Predicted kinase  ali follow..  11....................ILKFLEKQPKPEGRPFILGISGPQGSGKSTLASALDTELTVVKFSLDDFYLTHAEQVELAKNNPNNPLVQH---LAGTHDVTFLNNVLNAFVKGSDEETYVIFEGW-SLLWVNRKLADYQPIFQKIDSLVELEAQEINYVYRWRLQQEHALKARIHKGMSDEEVIEFVNHYMPQYVFYNPHCLEIILDENRYPVVM............ 276
44 -9.710[O] KOG0743 AAA+-type ATPase  ali follow..  11  750......................................LLYGPPGTGKSSLIAAMANYLKF------DVFDLELSSENAQLKSILLSTTNRSILVIEDIDCSSAEVVDREADEYQEYESGLLVDGL--TTNHKERLDPALLRPGRMDMHINMSYCTGLGFRTLVSN-GLGGLNHPLCEEIEALIDSTEVTPAELAEELMQE---------DDTDVVLRGVVSFVENR. 947
45 -9.510[S] KOG4308 LRR-containing protein  ali follow..  12  193................................EQGETIFILGDAGVGKSMLLQRLQSLW-----ATGRLDAGMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVA------FTFDGLDEPAHPLVLLANLLSGKLLKGASKLLTATGIEVPRQFLRK-LLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSL..................... 387
46 -9.380[T] COG5635 Predicted NTPase (NACHT family)  ali follow..  11  46.............................EDIAEIPCLVLLGEPGVGKTHELEKLQRFTEETICEYSKVLGLNLRTFTNLKEDLFRD-LDEGLLNVKSLAIGLVDEFKKPKYRSHINRLHLRLT---RTLAFPSILEEALKALWEESNFAIYELAP---LRRIDVINAVEAEGFSSDDFLKNQRDIVPLAIKPLLNTYRRHNSQFPPEQKRY--ESYLEGCKCLCEE. 261
47 -9.270[O] KOG0727 26S proteasome regulatory complex, ATPase RPT3  ali follow..  11  189..................................PRGVLLYGPPGTGKTMLAKAVANHTTFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAAIIFIDEVDAIATARFDAQTGADREVQRILMDGFDQTTNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLVFQ-SKMNLSDEVDLEDYVSRPDKIS-QEAGMHAVRKNRYVILPKDFEKGYRANVKKPDTDFE... 405
48 -9.260[R] COG1341 Predicted GTPase or GTP-binding protein  ali follow..  14  28..............................SLRKPAKVMIIGDVDTGKTTLTIYLANEL-IIDSDIG---QKGILPPATISLAFVDSHFTSGTITPNQYFGEMVVGVMKLSELAMKFSDVVLIDGMIYGS--GVELKRMKIEAVKPNLILALERNNELAPILKGYEDITIRLEVSEKAKDFSRSERRELRREKWRKYFENS........................... 214
49 -9.260[O] COG1222 ATP-dependent 26S proteasome regulatory subunit  ali follow..  15  182..................................PKGVLMYGPPGTGKTLMARACASKTNFLKLAGPQLVQMYIGDGARLVRDAFALAKERKTIIFIDEIDAIGAKRSDSDQTGDREVQRTMLDGFSSSTNRVDILDPALLRSGRLDRKIEFPLPNTLGRKRILQ-RKMSVRDDVNFDELARSTEGFNGAQCKAVCVEAGMAALRKEKTEISQNDFMDGIQEVLSRK. 393
50 -9.180[R] COG2607 Predicted ATPase (AAA+ superfamily)  ali follow..  11  81................................RPANNVLMSGARGTGKSSLVKALLHEYADKGLRLIEVDKSDLIGLPYLLTLLKECFCDDLSFESGDETYKALKTALDGGLSQRCANVLVYATSNRREIHQKEAVEEKISLSDRFGLWLSFYPFDQNDYLAAVQNWLEDFGVPYDETAQMAALQ........................................... 257
51 -9.170[L] KOG1532 GTPase XAB1, interacts with DNA repair protein XPA  ali follow..  11  27....................RVSAASSSSNFKKKPIIIIVVGMAGSGKTSFLHRLVCHTFVVNLDPAV-IRDTVK---------YKEVMKQYNLGPNGGILTSLNDEVVSVIEKRADQLDYVLVDTPGQIESGAIITEAFASTFPTVVTYVVDTPRSSSPITFMS-------------NMLYACSILYKTRLPLVLAFNKTDVADH...................... 218
52 -9.160[O] KOG0728 26S proteasome regulatory complex, ATPase RPT6  ali follow..  13  182..................................PKGVLLYGPPGTGKTLLARAVAHHTEFIRVSGSELVQKFIGEGSRMVRELFVMAREHASIIFMDEIDSIGSSRIESGSGGDSEVQRTMLDGFEATTNRIDILDPALLRPGRIDRKIEFPPPNEEARLDILK-RKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQK.. 392
53 -9.030[O] KOG0726 26S proteasome regulatory complex, ATPase RPT2  ali follow..  16  218..................................PKGVILYGPPGTGKTLLAKAVANQTSFLRVVGSELIQKYLGDGPKLVRELFRVAEEHASIVFIDEIDAVGTKRYDSNSGGEREIQRTMLDGFDSRTNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFT-SRMTLAEDVNLSELIMAKDDLS-TEAGLMALRERRMKVTNEDFKKSKESVLYRKKE...... 431

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.