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Query: [R] KOG3263 Nucleic acid binding protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSSSRSGEHRRNYAQGRNYESSRSRGDQRDRDYREYRRNYRDERSSRRYEDSQRRDYSPARRRDRYERHRESVREESPRRPVEHERNWQPELKHGRERFRERDYEGRRDRKERRDGVSPFSPEGEGLERKREHEKLQAPSPKEEEERPVDQGDKMDGVKEDKDGSLEVGKSHDAMTRTKSAEEEIVEQEDEATAEMKRIMGFSGFDTTTGKKHGDVGQVYKQKKTKYRQYMNRPGGFNRPLDNELast
1 -70.500[R] KOG3263 Nucleic acid binding protein  ali  100  1MSSSRSGEHRRNYAQGRNYESSRSRGDQRDRDYREYRRNYRDERSSRRYEDSQRRDYSPARRRDRYERHRESVREESPRRPVEHERNWQPELKHGRERFRERDYEGRRDRKERRDGVSPFSPEGEGLERKREHEKLQAPSPKEEEERPVDQGDKMDGVKEDKDGSLEVGKSHDAMTRTKSAEEEIVEQEDEATAEMKRIMGFSGFDTTTGKKHGDVGQVYKQKKTKYRQYMNRPGGFNRPLDNE 244
2 -19.500[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  10  514IEAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDTDAHWIIKQQTTSIPAPPSSQQN............................................................. 696
3 -18.400[S] KOG4610 Uncharacterized conserved protein  ali follow..  7  306LQLYRLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS.......................... 523
4 -15.800[A] KOG2217 U4/U6.U5 snRNP associated protein  ali follow..  16  94.AQVQAQAKLRDARESSNRDKERDSGRDRELLRERERERDRERERDRDREKEREREREKERLREREEREREREKERIREREKERLRERERERERERVRELTAPPPPQISKHAEYESRREREIERERDARKRSGRERERERNRERSRSQSPASSSRKPATKEREPSSRSFSPIPENGAGDVLSITETNKLRAK.................................................... 284
5 -13.300[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  15  255.RRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDR-EREKKKKRSKSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEKYRPPPAHHNMFSVPPPPILGRGNASTNPNPDNGQQSSGDPSWWRQ................................................ 448
6 -13.300[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  12  255.SRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMS............... 483
7 -13.100[R] KOG2140 Uncharacterized conserved protein  ali follow..  6  671.SSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK..... 908
8 -11.800[P] KOG4505 Na+/H+ antiporter  ali follow..  8  530.EEFPSEDYESRQPRRSNEEDREEEMNPGDETYLIGEDLVVEDSQGNIISHTSSRDANGPSIDEKLAQGDPKAKSFGRKFRSFLRRSYDTFQRNLHEPDDERQREPTLGHIESSIENHRPRYSRQNSESHLRENSVERRRREQVLTNIGDSESEDDNIPRPGIVPFYNENNESSSDTRNGLLSDNVSESRSRRPSRAPSAAVSSEGSPVEEDNEAQHRPNIRFLELTRAW.............. 758
9 -11.800[K] KOG2478 Putative RNA polymerase II regulator  ali follow..  10  358...................EKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD................................................... 531
10 -11.800[S] COG5291 Predicted membrane protein  ali follow..  7  212..........................................................NEHPSSCCKARKGITIREGRERHERNMGYSNASTTSGDSMASLTDMADTKSSTENSAVTEESQCCAESFKDSSVVSSQKSMAVSTVVGSSTEAKNNYLDFTEALCDKEVVAEQNPESQSNEEWDEKWGDSDNESECS................................................. 348
11 -11.100[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  9  7.NADDDGKRVQNEEGNYDPTDHQRQMEDYYKQYEEQRQVANSFHNTTGRPDLVAMQARLAETEQAIHRLNEEKKQPPPGFPIMTTPATQPEISIPRSGENKSSRSPSWAREARRSRSRSRDRRGGRSRSRSPSRRRTSRDRRDDRSSRRRRDRSHSRSRSPPSSANGSSHWSSSNRHSRRRRSRSYSRERDRNSRRDDRRSNLSNNDRYSDWNPGV............................ 221
12 -11.000[O] KOG0314 Predicted E3 ubiquitin ligase  ali follow..  10  513.AKKTEMKRKRENEIRRSEGGNVVRDSEKSRIMNNSAVTSSPVKPKSRQGPPPPISSDYDRRRRS-DRSSPERQSSRRFTSPPRSSSRKSERDRHHDLDSEHDRRRDRPRETDRKHRKRSEKSSSDPTVEIDDNNKSNVFTRISFPEESSGKQRKTSKSSPAPPESSVAPVSSGRRHHSRREREMVEYDSSDDEDRHFKRKPSRYKRSPSVAPSDAGDEHFRHSKRSKGERAR........... 743
13 -11.000[S] KOG2889 Predicted PRP38-like splicing factor  ali follow..  10  172....EEVDMLPSYKSLLDGDLVAMSDSDSEEEEVTKKEKPRLTSRRRSRSRDRERDVGDRREVREREKLKERRERGDDEPGPSSSGSGRRDDRDDRRRDRDRSRDRDRRDRRDDDRRDKKKESRRGGADNDEEREIAEANALRAKLGLAPLER........................................................................................... 320
14 -10.900[A] KOG0796 Spliceosome subunit  ali follow..  22  285LQEEKNKVHKERVEERRSKERSRERESSKDRDGGDNRDRGRDVDRRSRDRDRHHDHREHDRNYNQSRGYDSRSRRSSRSRSRERPRDHDRRRRHDR.................................................................................................................................................... 380
15 -10.800[R] KOG2888 Putative RNA binding protein  ali follow..  18  266.AGSRSNAYPQPNNYRNDYDERDYYAAASGSSYGRGRGGYEDYPPAPLPPQMPYGERERERDRDR-DKNKDYDRHRSKHKKKHNHRQSSRSRSRSRSRSRHRSERHERKRDGGGYERSSKSRHNEHYEERERRHR............................................................................................................. 398
16 -10.100[R] KOG2295 C2H2 Zn-finger protein  ali follow..  9  283.VYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSIFLRNLAPS 525
17 -9.630[S] COG5604 Uncharacterized conserved protein  ali follow..  7  4LSSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETDAMAKEIDENERLKSSSGKIVLTSDTIQQWQKLLETNHS..................................................... 194
18 -9.630[J] KOG2256 Predicted protein involved in nuclear export of pre-ribosomes  ali follow..  7  4LSSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETDAMAKEIDENERLKSSSGKIVLTSDTIQQWQKLLETNHS..................................................... 194
19 -9.340[S] KOG4463 Uncharacterized conserved protein  ali follow..  8  217...........................................................................RPPYSDMQNASTFNPETLFALPTGLDAERTENENQVENPVSNADANDSPTRQNARATAIASSSNTAASFRNRQQISHPPLGRTSSSSVLPTGPASQLYDMLSGRSERPELGNIREEDINTVQTIMQTSRAQAIQALSQTNDVQRAVE--------LEQTADY....... 372
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.