current user: public
If you have questions about the server, please let us know.

Query: [P] KOG3713 Voltage-gated K+ channel KCNB/KCNC, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490
# Score Template Links and tools%idFirst MDGSGERSLPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIPLLTEEKHHRTRLQSCKLast
1 -123.000[P] KOG3713 Voltage-gated K+ channel KCNB/KCNC  ali  100  1MDGSGERSLPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIPLLTEEKHHRTRLQSCK 494
2 -94.800[P] KOG4390 Voltage-gated A-type K+ channel KCND  ali follow..  29  23....ASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLGSS------------ERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDAD---TDTAGESALPTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVM-------TDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQSSEDEQAFVSKSGSSFETQHHHLLHCLEKTTNHE.. 492
3 -43.200[R] KOG3840 Uncharaterized conserved protein, contains BTB/POZ domain  ali follow..  9  114.MLMSQLGGRQGNTVDCSPGEGDKVCLLVDQTRFLVSQRLLTSKPDTMLGRMFS--MRASCGDLGADLVSPNERDEFEVADGSSCFRAILDYYQSGTMRCPSSVSVSELREACDYLLVPFNAQTVKCQNLHALLHELSNEGAREQ------------------FSQFLEEIILPQLVASTEHGERECHLVVLLDDDVVDWDDEYPPQMGEETTHVVYSTHLRDCAKQVLKERGLKKIRLGMEGYPTHKEKIKKRFNKAEVIYNYVQRPFVHCSWEKEEARSRHVDFACPIVKS-----------KSNPSLAAAASDPLPQPAPLQQQH...................................................................................................................................................................... 420
4 -34.700[R] KOG2715 Uncharacterized conserved protein, contains BTB/POZ domain  ali follow..  14  25...CRRCSAGLGALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDE--------TGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITS-LIKLVKDKIRERDSKTSQVPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSY........................................................................................................................................................................................................................................................................................................................... 191
5 -34.000[R] KOG2723 Uncharacterized conserved protein, contains BTB/POZ domain  ali follow..  12  35.SPVSPLAAQGIPLPAQLTKSNAPVHIDVGSHMYTSSLATLTKYPDSRISRLFNGTEPIV---------LDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGERGEKALIEEVFPETGDVMCNSVNA............................................................................................................................................................................................................................................................................................................................ 207
6 -25.400[P] KOG2716 Polymerase delta-interacting protein PDIP1 and related proteins, contain BTB/POZ domain  ali follow..  16  2.....................SEAVKLDVGGTIFKTSKSTLTKFDGFFRTMLGSGIGLNVDE-----------SGCIFIDRSPKHFDLILNFMRDGCLALPKNERLTELMAEAQYYLLDG-LIDRLASSNWSVESDEKT................................................................................................................................................................................................................................................................................................................................................................... 108
7 -21.500[P] KOG3684 Ca2+-activated K+ channel proteins (intermediate/small conductance classes)  ali follow..  15  281.....................................................................................................................................................................................KRLSDYALIFGMFGIVVMVIET--ELSWGLYSKDSMFSLALKCLISLSTI-ILLGLIIAYHTREAQLFVIDNGADSLEMLVCAPGFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTTRFVMKTLMTIGTVLLVFSISLWIIAAWTVRACERYDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAA.......................................................... 573
8 -20.600[R] KOG2714 SETA binding protein SB1 and related proteins, contain BTB/POZ domain  ali follow..  17  2......AGGHCGSFPAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRD----------ETGAIFIDRDPAAFAPILNFLRTKELDLR-GVSINVLRHEAEFYGITPLVRRLLLCEELERSSCGSV................................................................................................................................................................................................................................................................................................................................................................... 123
9 -19.300[P] COG1226 Kef-type K+ transport systems, predicted NAD-binding component  ali follow..  22  3................................................................................................................................................................................................................................................................................................................................WPLFIRIGVIILCLILLFGQIIYILE----PKQFTSVFEGIWWAVVTVSTVGYGDYVPHTPLGQAAGILLILSGASFVTAYFATLSAAAFSRQHRYIEGKVAYKGRDHII................................................................ 108
10 -17.300[P] KOG0501 K+-channel KCNQ  ali follow..  12  19......................ENIVRRSNDTNFVLGNAQIVDWPNDGFCKLSGYHRAEVMQKSSTCSFYGELTDKDTIEKVRQTFEN-ILMYKKNRTPVWFFVKIAPIRNEVVLFLCTFSDITA---QQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFK---------TRQNNVAWLVVDSIVDVIFLVDIVLNFHTT--RMNYLKTWF-VIDLLSCLPYDVINAF------ENVDEGISSLFSSLKVVRLLRLGRVARK------LDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQ............................................................ 500
11 -15.600[PT] KOG0500 Cyclic nucleotide-gated cation channel CNGA1-3 and related proteins  ali follow..  13  173...............................................................................................................................................................................................TAIALPVFYNWYLLICRACFDELQSEYLMLWLVLDYSADVLYVLDVLVRARTG--WQHYKTTTQFKLDVLSLVPTDLAYLK---------VGTNYPEVRFNRLLKFSRLFEFFDRTETRTNYPNMFR-----IGNLVLYILIIIHWNACIYFAISIPEHGRLSRKYIYSLYWSTLTLTTIGETPP-PVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEFQAKIDSIKQYMQFRK............................................................ 428
12 -14.400[PT] KOG0498 K+-channel ERG and related proteins, contain PAS/PAC sensor domain  ali follow..  14  79........................................................................................................................................................................WN-----------KIFLFACVVALAIDPLFFYIPIVDS-ARHCLTLDSKLEIAASLLRTLIDAFYIIHIVFQFRTA--ALKYLSSYF-IIDLLSILPLLAVIPSVNQPVSLLTKDYLKFSIIAQYVPRILRMYPLYTEVT--RTSGIVTETAWAGAAWNLSLYMLASHVFGALWYLISVEREDRCWKKFFYCFWWGLRNLSALGQNLQTSKFVGEIIFAISICISGLVLFAL----LIGNMQKYLESTTVREEEMRVRKRDAEQ.............................................................. 413
13 -14.400[PT] KOG0499 Cyclic nucleotide-gated cation channel CNCG4  ali follow..  14  223...............................................................................................................................................................................................LLVTLAYNWNCWFIPLRLVFPYQTADNIHYWLIADIICDIIYLYDMLFIQPRL--RKHYRTSTKFQLDVASIIPFDICYLF----------FGFNPMFRANRMLKYTSFFEFNHHLESIMDKAYIYR-----VIRTTGYLLFILHINACVYYWASNYEGDGEGNEYLRCYYWAVRTLITIG-GLPEPQTLFEIVFQLLNFFSGVFVFSSLIGQMRDVIGAATANQNYFRACMDDTIAYMNNYS............................................................ 470
14 -12.100[P] KOG3733 Mucolipidin and related proteins (TRML subfamily of transient receptor potential proteins)  ali follow..  11  357............................................................................................................................................................................................................................FVLILCILSLILCCRALIKAHLLQIKTSDYFENVLKVNDALIIIGTVAKISIEFQDFDNSLFTLTSIFLGMGALLVYVGVLRYFGFFSQYNILMLTLKRSAPNIMRFMTCAIVLYAGFLIAGWVI--GPYSMKFRTLAE----SSEALFSLLNGDDMFATVFGTVIYLFVSLFIYVVLSLFIAIIMDAYEVVKDRYSDGLRAIEKRGCLRDFVESNPPPSELGSPTTRSAYAPS........................................ 618
15 -11.700[P] KOG4404 Tandem pore domain K+ channel TASK3/THIK-1  ali follow..  11  37.......................................................................................................................................................................VFSALELAHERQAKQWEERLANFSRGHNLSRDELRGFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTI-TTPATVG---KIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEG-------SYFDSLYFCFVAFSTIGFGDLVSSQNAHRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSGCCPQCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMISMKDLLAANKASLAILQKQLS 368
16 -10.500[P] KOG1418 Tandem pore domain K+ channel  ali follow..  15  142.....................................................................................................................................................................................................................................................................................ESTIREEFKQQYRETWGHWFVRVGKFLYKLLGIQYMLLAL--------MILGYACLGGYIFLTL----EYDQQQLDLEVEKQVKVERDIRGEGWRYGNLACKTNLGRVATIIYGLIGIPLMLFVLKHSIKWAQKVRYSIRRCVKRCFRRSKLKRASTIESVASDEMPCEESGISEDEEQI..................................... 355
17 -9.440[PT] KOG3676 Ca2+-permeable cation channel OSM-9 and related channels (OTRPC family)  ali follow..  11  419.......................................................................................................................................................................LNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKIGDYFRVTGEILSVLGGVYFFFRGIQ---KTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVASMVFSLA--LGWTNMLYYTRGFQQMGIYAVMIEKM---LRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPS--NSLYSTCLELFTIGMGDLYDFKAVFIILLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKL-QRAITILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVK 771
18 -9.220[S] COG3952 Predicted membrane protein  ali follow..  15  10.............................................................................................................................................................................................................................LYPLGFLASLFFGSAFSIQWWLSKKRKEVYAPRLSSIGATLMIVHGT--------IQSQFPVTVLHVINLIIYLRNLNITSSRPISFRATLVLMALSVVFVTLPFLHLIGCLGLAIFSGRFLIQWFYIESNNTKDFPLLFWK---------------IGLLGGLLALVYFIINILCYGCGLFPSIANLRLFYKEQRSTPYLDTH..................................................................... 223
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 2 2   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li Z, Ye Y, Godzik A. Flexible Structural Neighborhood--a database of protein structural similarities and alignments. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D277-80.