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Query: [D] KOG3859 Septins (P-loop GTPases), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELPQSQGSQAGGSQTLKRDKEKKNNPWLCTELast
1 -129.000[D] KOG3859 Septins (P-loop GTPases)  ali  100  1MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELPQSQGSQAGGSQTLKRDKEKKNNPWLCTE 434
2 -102.000[DZ] COG5019 Septin family protein  ali follow..  34  55.DNSEQEFNPHVSIIQRQLNGYVGFASLPNQWHRRCVRQGFNFNVLVLGESGSGKSTLVNTLLNRDVYPPTGVNPEPTVMINSSAVEIVENGISLQLNVIDTPGFGDFIDNTDCWQPVLTDIEGRYDQYLELEKHNPR--STIQDPRVHACIFFIQPTGHAISAMELRVMLALHEKVNIIPIIAKADTLTDDELNFTKEMILRDIQYHNIRIFFPPTYETDDPESADIMSRIPFAIIASNTFVVNNEGKRVRGRRYPWGVVEVDNEEHSDFPKLREMLIRTHLEELKEQTNK-LYEAYRTERLLSSGISQDHSVFREVNPSAKLEEERALHEEKLMKMEAEMKTIFSQKVQEKEDRLKQSENELRTRHREMKAALEKQKADLIDHKNRLMQAKAAAENEKSKRKFFK........................... 469
3 -94.200[DZU] KOG2655 Septin family protein (P-loop GTPase)  ali follow..  38  10................IETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERIEKQKQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSNSFGAILEYIDEQYERFLRDESGLNR--RNIVDNRIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILRLKCRIMQEIESHGIKIYPLPDEDEDYKEQVKQLKEAVPFAVCGANTLLEVKGKKVRGRLYPWGVVEVENPDHCDFIKLRTMLI-THMQDLQEVTQEVHYENYRSDRLAKGIKGKENGVKAER------DSSSQVVSNSVLGEKDRILQEKEAELRRMQEMLAQMQARMQAQQ.................................................................. 361
4 -79.800[DTZ] KOG1547 Septin CDC10 and related P-loop GTPases  ali follow..  39  240.DAGLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKR-IPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSELVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMANGVEEKEPEAPEM.............................................................................................................. 568
5 -18.900[R] COG0218 Predicted GTPase  ali follow..  22  27...........................................EIALAGRSNVGKSSFINTMLNRK-------NLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYG--------YARVSKKEREKWGCMIEEYLTTRENLRA---------VVSLVDLRHDPSADDVQMYEFLKYYIPVIIVATKADKIPRGKWNKHESAIKKKLN.................................................................................................................................................................................................................................... 166
6 -16.900[R] KOG2486 Predicted GTPase  ali follow..  18  137...........................................EFALVGRSNVGKSSLLNSLVRRK-------RLALTSKKPGKTQCINHFRINDKWYLVDLPGYG--------YASAPHELKQDWNKFTKDYFLNRSTLV---------SVFLLVDASIPVKPIDLEYASWLGQNVPMTLIFTKCDKRKKKKNGGKKPEANIKEFQDLIQGF............................................................................................................................................................................................................................. 283
7 -14.100[R] COG3596 Predicted GTPase  ali follow..  16  16........................LSGLPLWVSERILQQINQLVIGIMGKTGAGKSSLCNALFAGEVS---------VSDVAACTRDPLRFRLQIGMTIVDLPGVGESGVRDT------EYAALYREQLPRLD-----------------LILWLIKADDRALATDEHFYRQVIGEAKMLFVISQSDKAEPTS................................................................................................................................................................................................................................................. 164
8 -12.500[O] KOG0448 Mitofusin 1 GTPase, involved in mitochondrila biogenesis  ali follow..  64........................LSIIGEVLSRR------HMKVAFFGRTSSGKSSVINAMLWDKVLPHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSW---IDKFCLD--------------------------VFVLVANSESTLMNTEKHFFHKVNSKPNIFILNNRWDASASEYMEDVRRQHMERCLHFLVEELKVANALEAQNRI---------FFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLADRCTDEVNALVLQTQQE........ 475
9 -11.100[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  11  57...........................................TVLLSGLSGSGKTVLFYQLRDGSSHQGAVTSMEPNETFVLHNENNTKKGKVKPVHLIDVPGHSR--------------LISKLEEYLPR---------------AAAVVFVVDALEFLPNIRAAEYLYDIKNKTPVLLCCNKTDKVTAHTKEFIRKQMEKEIDK................................................................................................................................................................................................................................... 200
10 -10.900[R] KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily)  ali follow..  11  170...........................................TVLICGYPNVGKSSFMNKVTRADVDVQPYAFTTKSLFVGHTDYK------YLRYQVIDTPGI----------------LDRPFEDRNIIEMCSITALAHLRA----AVLFFLDISGSCGYTIAFHSIKSLFMNKPLVIVCNKTDLMPMENISEEDRKLIEEMKSEAMKT-VLLKMSTLTDEGVMSVKNAACERLLDQRVEAKMKSKKINDHLNRFHVAIPKPRDSIE-PCIPQVVLEAKAKEAAAMEKRKTEKDLEEEQHDEWKEDIMPEILDGHNVADFIDPDILQRLAELEREEGIREAGVEEADMEMDIEKLSDEQLKQLSEIRKKKAILIKNHRLKKTVAQNRSTVPRKFDKDKKYTTKRMGRELSAMGLDPSSAMDRARS...... 558
11 -10.800[R] COG1084 Predicted GTPase  ali follow..  15  164...........................................TVVIAGFPNVGKSTLLRTLTGAEPEVADYPFTTKGIQIGHLERK------WKRIQVIDTPGL----------------LDRPVEDMNNIELQAMVALENIAD----VIMFIFDASETLESQYSLYLGIRSVFDIPVVTVFNKMDLAENVKVSKIIKKLEGLYEKETREA.............................................................................................................................................................................................................................. 332
12 -10.600[R] COG2229 Predicted GTPase  ali follow..  16  3.........................................ENKIIFTGPVGVGKTTAIAAISDEALVQTDASASDMTLDRKRNTTVAMDYGADTKVHLYGTPG------------------QERFNFMWEI----------LSQGSMGLVLLLDNARTNPLKDLELHSFRGLLEKAPVVVGITKMDIRSQPGIDVYHKYLAK--HNLNVPVFEIDARKEDD.................................................................................................................................................................................................................... 160
13 -10.500[E] COG4917 Ethanolamine utilization protein  ali follow..  17  3...........................................RIAFVGSVGAGKTTLFNALQGNYTLARKTQAVE-------------------DKGDIDTPG-----------------------EYFNHPRWYHALITTLQDVDM---LIYVHGANDPESRLPAGLLD-IGVSKRQIAVISKTD-MPDADVAATRKLLLE....................................................................................................................................................................................................................................... 117
14 -10.100[T] KOG3886 GTP-binding protein  ali follow..  11  1MEESDSEKTTEKENLGPRMDPPLGEPE--GSLGWVLPNTAMKKKVLLMGKSGSGKTSMRSIIF-ANYIARDTRRLGATILDRIHSLQINSSLSTLVLNLWDCGG-------QDTFME--NYFTSQRDNIFRN---------------VEVLIYVFDVESRELEK--LEAILQNSPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRR................................................................................................................................................................................................................................... 211
15 -9.970[TU] KOG1954 Endocytosis/signaling protein EHD1  ali follow..  15  95............................................ILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGSIP-SVTIVDTPGI-QRIDRGYDFTGVLEWFAE----------------------RVDRIILLFDAISDEFKRC-IEALAGNEDKIRIV--LNKSDMVDHQQLMRVYGALMWSLGK................................................................................................................................................................................................................................... 276
16 -9.890[U] KOG3887 Predicted small GTPase involved in nuclear protein import  ali follow..  15  64...........................................RILLMGLRRSGKSSIQKVVF-HKMSPNETLFLESTNKICREDVSNSSF---VNFQIWDFPG------------------QIDFFDPTFDYEMI---------RGTGALIFVIDSQDDYMEALAVTRAYKVNTDINFEVFIHKVDGLSDDHKIETQRDIHQRANDD.................................................................................................................................................................................................................................. 203
17 -9.170[R] COG1159 GTPase  ali follow..  14  11............................................IAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTE------PYQAIYVDTPGLHMEEKRA-----INRLMNKAASSSIGD---------------VELVIFVVEGTRWT--PDDEMVLNKLRDKAPVILAVNKVDNVQEKVLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHLPEAIHHFPEDYITDRSQRFMASEI-----------------IREKLMRFLGAEL--YSVTVEIERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVVKVKSGWADDERALRS.................................................................... 294
18 -9.090[R] KOG1489 Predicted GTP-binding protein (ODN superfamily)  ali follow..  13  301..................GQGGLGNMHFLTNLIRNLFELKSIADLGLIGLPNAGKSTILNKISNAK----PKIGHWQFTTLSPTIGTVSLGFGQDVFTVADIPGIIQGASLDKGMLEFLRHIE-----------------------RSNGWVFVLDLSNNDLQLLEVGTLEKVKTKNILI-VCNKVDIDAEKSSFAKYLQVEKFSKSQEWDCVPISALREKT.................................................................................................................................................................................................................... 499

FFAS is supported by the NIH grant R01-GM087218-01
1 3 5 7 6 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Godzik A. Fold recognition methods. Methods Biochem Anal. 2003;44:525-46. Review.