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Query: [R] KOG4264 Nucleo-cytoplasmic protein MLN51, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPAYIPRKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRGSSLast
1 -153.000[R] KOG4264 Nucleo-cytoplasmic protein MLN51  ali  100  1MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPAYIPRKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRGSS 703
2 -19.000[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  12  1MTKKLALKRRGKDSEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQSSSAEEDEESSDEEDNEEEESTDGEEVEDEEKDSKSKQTDDKPSGSGAASKKALTAELPKRDSSKPEYQDSDTS-----------------DEEDIRNPMYYKHIG--YDWDAKKIIKPPQGDQIDEFLRKIEDPDFWRKDPLTGQDRLTDEDIALIKR----IVSGRIPNKD.................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 242
3 -17.000[R] KOG4334 Uncharacterized conserved protein, contains double-stranded RNA-binding motif and WW domain  ali follow..  11  1MEQESGGKKSNEQLLSEREAIMRQLAMLGSGPEDLDVDDEEEDEEEEVEKMEEGVEETMENASVVKETTPVKDENIVEDSNSSEELFPYLDSPPEDKIQEISANDTEIDQIDSPIRFEGVKNPAQKMDVDGEEGTSTD------ARPVSGSSGSSVGEQIRAPVPVLKTIMDRIDLDKSNPLPE---------------------------------WSHQ-YYHKFSKP---------YEGIVRDHEIPVSSIPCLYKKIMDELHENVEKQ............................................................................................................................................................................................................................................................................................................................................................................................................................................... 240
4 -16.800[R] KOG2295 C2H2 Zn-finger protein  ali follow..  9  290..QMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPI---------KNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSIF---LRN......................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 521
5 -15.500[K] COG5164 Transcription elongation factor  ali follow..  8  1MSDNSDTNVSMQDHDQQFADPVVVPQSTDTKDENTSDKDTVDSGNVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDDDEDDDDEAP-DEDEDEDEEDSELVREGFITHGDDEDDEASAPGARRDDRL--QRLAKELRERYGRSSSKPSVDTATI----WGVRCRPGKEK................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 298
6 -15.000[K] KOG2478 Putative RNA polymerase II regulator  ali follow..  9  359..KELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 531
7 -14.000[A] KOG2217 U4/U6.U5 snRNP associated protein  ali follow..  10  1MGSSSSGKKHKKDKKNRHRSRSSERPRRVTEDEDVTLDLTDDSSSRHRHHKHKKHKEHRHKHHKQKERERANEVISLEESDSDSSDCVEVPVQAQVQAQAKLRDARESSNRDKERDSGRDRELLRERERERDRERERDRDREKEREREREKERLREREEREREREKERIREREKERLR-----------ERERERERERVRELTAPPPPQISKHAEY-ESRREREIERERDARKR---------SGRERERERNRERSRSQSPASSSRKPATKEREPSSRSFSPIPENGAGDVLSITETNKLRAKLGLKPLEVDSGPSKAGPPPGSSSQGEIKKPHGEADLSSYKDEWGEFLHKPADNLKEKREAEKLREKLKQRKEKRFLEER............................................................................................................................................................................................................................................................................................................................... 363
8 -13.900[S] KOG2428 Uncharacterized conserved protein  ali follow..  12  2.............SSSEGNSDASAPGTPVKSSTPSSRGSSPDSPKKQEPSKKRAILNESDDDDDSRPAPRQLSDSSDDNIHPRGGGEKSSPGAGGGLFGDLSGSSDDDSDREGKPKESNTRARLSDSDAESRGSLNDLQGIVMANPDEIDEDEKAKEHVHDTEMVTGRVTLEYAADP-PNFLTH--PFYEEDEDDEQAKLDDEGRTRLKLRVENTLRWRVRKDENGKEIRESNAKIVK--GFEVSLVP....................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 257
9 -13.800[R] KOG4227 WD40 repeat protein  ali follow..  10  652.DIESVERKIYKAYKWLRYSYISYSNNKDGETSLVTGEADEGRAGTSHKDNPAPSSSKEACLNIAMAQRNQDLPPEGCSKDTFKEETPRTPSNGPGHEHSSHAWAEVPEGTSQDTGNSGSVEHPFETKKLNGKALSSRAEEPPSPPVP---KASGSTLNSGSGNCPRTQSDDSEERSLETICANNGRLHPRP-NNGQNLGELEVVAYSSPGHSDTDR--HD----SEMACETPN---------TREDPTDTPATDSSRAVHGHSGLKRQRIELEDTDSENSSSEKKLKT.............................................................................................................................................................................................................................................................................................................................................................................................................................. 942
10 -13.400[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  9  539....................................................................................................................................................................HPKELDIDSEGESDPLWLRQKTIQMIDEFSDVNEGEKE--------------LW--NLHVMRHG-PIACEMFLDAKGTEIVRKN--------------------FDYGLIAAETVYK--------------QGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATA----------NERLPGVAPHRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHRPPPPPPPQ........................................................................................ 955
11 -13.200[J] COG5593 Nucleic-acid-binding protein possibly involved in ribosomal biogenesis  ali follow..  12  635FAYRNPKKSAAARGHSIMQPLAGGLSKGYVPGSTYSGVPMNSEQFTSKKQEEIPVDELFFYRFFNDKYIKGKQARKTKVDRDEEGEIDEDEVWKALVDSKPQLEMDEEESDFDSEEMDKAMTDMGSDSEQSADENDNESMASEEKPMFSDEENLSEIAHSEDEFDDTVDFFEDENDLLPF---------DDEEEIQTVDHSETHSHKKKKRKAIKDL---PVFADAES-----AHLLE................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 859
12 -12.900[Z] KOG1425 Microfibrillar-associated protein MFAP1  ali follow..  12  139.RAQEEAALLPLEEEDEIQEEEEEEEESEYETDSEDDMPGIALIKPVFVPKAERDTIAERERLEAEEEALEELAKRKLEQRKIETKQIVVEEVRKDEEIRKNILLEEANIGDVETDDELNEAEEYEVEIGRIKRERDAREAMLREREEIEKLRNMTEQERRDWERKNPKPSSAQPKKKWNFMQKKGAFFQ-ADPDDEAGSAGTDGIFQRDFSAPTGE---DRLDKS---PKVMQ--VKHFGWHLVNED....................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 392
13 -12.700[O] KOG0802 E3 ubiquitin ligase  ali follow..  8  336.......................................................................................................................................................RIALGALHAALPDATSEELRAYEPMAKAKRLH--NHLF-H--R----------------------SWLDQGLNEVYSCPTCRKPLF---------VGRTENEVNPRTVEVSSDEQLARQLERQNNPVHALATGLFPAEVPDSVENDTSRNLGLDPSWLQTWSSQGSDVAGPSTTSRTVGLGRVQMMMRHLASVGESYAQTALDDAAWSLWPMNPSQASTSSTTVPPGNGGRTGGLHLRTVSNTTNESLTNILAMAETVREVMPHVPDEIIFQVN...................................................................................................................................................................................................................................................................................... 586
14 -12.500[S] COG5604 Uncharacterized conserved protein  ali follow..  8  5..........................SSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETD-----------AMAKEIDENERLKSSSGKIVLTSDTIQQWQKLL--ETNHSLTTLQKVVQAFKAAAFLNEEEAEDLK................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 220
15 -12.500[J] KOG2256 Predicted protein involved in nuclear export of pre-ribosomes  ali follow..  8  5..........................SSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETD-----------AMAKEIDENERLKSSSGKIVLTSDTIQQWQKLL--ETNHSLTTLQKVVQAFKAAAFLNEEEAEDLK................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 220
16 -12.500[A] COG5181 U2 snRNP spliceosome subunit  ali follow..  9  1........................................................................................MSTVEDVEIERLRAERELLRRQKEAAKNSSTNGSVNIEGTQDSNDLQYNAHLFKSSNPKEESAIDVRNDISQDEDDYKRTNDVNDSYRLVRQYAPKE------NEYADESYDPMQERQSKKQIQDRESDYQKDAFQPDGTQSNGR-----SYA-EVMRQVELEKEERRVHMELNQRRREGTLKEVEEEESISDKKRELELNNTEISQKPKRSRWDQAPPSVTQVSTTKRRSRWDKAPENFTISEHVIENGISED......................................................................................................................................................................................................................................................................................................................................................................... 259
17 -12.500[J] KOG2147 Nucleolar protein involved in 40S ribosome biogenesis  ali follow..  9  172.EDMISNLIAKTKLARHEKQQQKDELELMTESLDSKYQALMGKMKASFRPTGRQPLEKDDYDKLTITLKTEADARATPADRKLSEEEEALKEKERLETLEAAPDADVDIDAGSKADARKVQAKNSRFEVKFDDEGGLIDEDTVEKSRILKKNLDGSDESDDDEDLEDEEEDLDDLLED-----------EDELEEDSDDEEAQEAQKVVKKAKKSAPEPAETLPFVFEMPKNYKKFCAL................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 398
18 -12.300[S] KOG4610 Uncharacterized conserved protein  ali follow..  8  316.AEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKAR---------RRKHRGSSSDTSSGDSSSSSSSSSSSDS...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 522
19 -12.200[P] KOG4505 Na+/H+ antiporter  ali follow..  7  457...FNLPRVRQGQSLPIKRVDALRSSANSIASSIRRRHPVNIQEDEDADISTVSLPEAAHLREERAESPRGGHYDAEEFPSEDYESRQPRRSNEEDREEEMNPGDETYLIGEDLVVEDSQGNIISHTSSRDANGPSIDEKLAQGDPKAKSFGRKFRSFLRRSYDTFQRNLHEPDDERQREPTLGHIESSIENHRPRYSRQNSESHLRENSVERRRREQVLTNIGDSES---EDDNIPRPGIVPFYNENNESSSDTRNGLLSDNVSESRSRRPSRAPSAAVSSEGSPVEEDNEAQHRPNIRFLELTRAWE.......................................................................................................................................................................................................................................................................................................................................................................................................... 759
20 -12.100[B] KOG2266 Chromatin-associated protein Dek and related proteins, contains SAP DNA binding domain  ali follow..  8  1MGEDTKATIEPTANKTTSLEKPSEAMAGKENAGGKETQELAKDEDMAEPDNMEIDAQIKKDDEKAETEDKESEVKKNEDNAETQKMEEKVEVTKDEGQAEATNMDEDADGKKEQTDDGVSVEDTVMKENVESKDNNYAKDDEKETKETDITEADHKKAGKEDIQHEADKANGTKDGNT-----------GDIKEEGTLVDEDKGTDMDEKVENGDENKQVENVEGKEKEDKEENK.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 224
21 -11.900[KB] KOG3265 Histone chaperone involved in gene silencing  ali follow..  9  163..TVFVESNKALHLTSNEDDCSGNYKTCINNSSDSFVENLSRKIETEDLRVTTFPIRWTDEDPVAEPVDEEANKVFDEDDLMPLHDDGQDDDEEEEDDDETGPNTEEVDLNESFNERMANAHDGTEQKNGEESMEHDGASGDVEMGDNQLFVQINTDTKATESMVDPLSDTTKRDFRS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 338
22 -11.800[S] KOG4829 Uncharacterized conserved protein  ali follow..  9  1MA--RTELEKKVKRQGKKRKHEVTKNPEHAASDDEVANKSLILAPQVDQQEVPTDKPAKRRHKESEVSATKKQSRKNQAEEQVATSGSDESLPQKPQKRKQVQDANETKKLKRSKTQENNSDEDDDVDSQPTAAQLKEAARPENAYAVVTVRQKKKQKHQQRLEAQKSQSSNKDAKVNKEYL--------------------------LKWKESRQDW---KFNKLRQIDDELWPTALEYG--ARS......................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 231
23 -11.700[R] KOG2030 Predicted RNA-binding protein  ali follow..  9  695.ITAFPNTEVKIEHDTGRIIVRSDSVNPEIEETKESEVVLDKILKKTDDEETTIILAGPSRKKQVSAKKTKEDKARAKQEAAKQEVPPVSSEPKNPSQVKRGQKGKLKKMKQKYKDQDDEEREIRMMILKSSGKEKPQASADKVVEKSESTKEYVKPEKSAAPKNPVELDDADEVPVQPH-IPVVAPYYKFKVK-------TPGTGKRGKAAKLA-----NIFAKEKSCSAREKDLLKS----IKEES....................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 951
24 -11.500[S] KOG3100 Uncharacterized conserved protein  ali follow..  12  375..WNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEEKKKNELLQKA----------SESKYQLQKKRRKERQKTAGDGWKNDRFNDRDGFPKSREDCWLDHG.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 736
25 -11.400[A] KOG2242 Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain  ali follow..  9  29LAERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDD-INEEISVKHLPSTEPDPH---SLDSCSTQLGEEPFSYGYG------TGKKSTNSRFENYG-DV........................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 328
26 -11.200[L] KOG0981 DNA topoisomerase I  ali follow..  13  1MSSSDSDSVSLSIRRRQRRGSSKRISMKESDEESDSSENHPLSESLNKKSKSESDEDDIPIRKRRASSKKNMSNSSSKKRAKVMGNGGLKNGKKTAVVKEEEDFNEIAKPSPKHKRVSKANGSKNGAKSAVKKEESDTDDSVPLRAVSTVSLTPYKSELPSGASTTQNRSPNDEEDEDEDY-----KWWTSENIDDTQ------------------KWTHNIFAPPEPLPKEAEEVAGFYAAMLETD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 245
27 -11.200[S] COG5139 Uncharacterized conserved protein  ali follow..  8  1MSEEEKAELENMQVESEAKTSENDQTIDTKVDVADVTTHVDEDLDNKEEALDFSEDELSDLDENQFENFDESKIGREAEEPTIYNLPTFKKKQEPNTIEENLEVPRKVRKEQKPRRRRGKRSSTVDALNDELNELGENEEEVLTEQKQLDPTDAVLKPTRTKKRSNEDNLEQMADDEVLRLREQMRLAALRDAELNSEQLPATEKLKRKTHLYDT-MW----------EPLPDRSL----ALNIQRS........................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 265
28 -11.100[S] KOG4051 Uncharacterized conserved protein  ali follow..  9  206..KEPIKEVQSDEKELQREHMSEEEQKMKSTNKTAAPVRKSQRLKRSKEVKFEDEEKEEIEEDNTKDEEQKEKKEEIQEPKITHNEEVDKEKNENEEGDDEREKSTSYENTNGSESEGVDEGVDEELGYESEREAEGKGKQIESEGGNLKKKTENKKGDDQQDDTKKDSKDKNEPLAKRT---------RHSSSTGNTSNETSPKRKRRKAGSRKNS------PATRVSSRLRNK.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 424
29 -11.100[KU] KOG2773 Apoptosis antagonizing transcription factor/protein transport protein  ali follow..  11  1MLRKSKKQPQTVAEKESDSAEDSDFDVATGPRLVDFEEEEYDLPDARSTDFRKRNVKLLSEQSDRYKGKISSRKELDDDEDKDDEQEVSYEESDEDDENLTNFKQKLNAGGAEDSEEETAAGHSESGEESEEIESNLTDFKKKFEAGDFKYDDDEEEDDDSEEEDHSQESEGDDDDSEDD---------IKPSDVMSKTNHQAEIQKGLAVQNQLRIWEQKFTSKANQLPAP....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 247
30 -10.900[S] KOG2690 Uncharacterized conserved protein, contains BSD domain  ali follow..  12  245ISLDDEEELSWDIDDEEESSEKVVEATKDVSRLKLEGNDGMGGGDVSETVKDEVESTYSVAKVSTQDEVTSADSVTEVSNVGLKTDKDSEEKKETDSEEVPEEKSFVDAAPPASDEAPIQDSVKPTSDEAPIQDSVKPKSDEAAPSQDSAKPDVAASSSTQQPSEEDLGWDEIEDMSS-----------GKETSRSGGSPNRAELRKRLSAAEEDEDLSWD--DEDDEEESSSSK.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 469
31 -10.900[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  9  227.SEPVKEESSELEQPFAQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSPEDDSDTKRLSKEEKGRSSCGWV-KYGK----NARSPGAR------------------YGFVTMSTAEEATKCINHLTELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKCDRKDDAKKGDDGSGEKSKDQDDQKPGPSERSRATKSGSRGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSASREKRSVVSFDKVKEPRKSRDSESHSRVRERSEREQRMQAQWEREERER.................................................................................................................................................................................................................................................................................................... 644
32 -10.800[S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7  ali follow..  8  419.NEKKDEEKKKKAAEEALKSKEEAEKAKVQEKEKLVDVAAQAIVHELKKDIYDAVASTSSTTEAKEPAAKPSEAKEEKKEDITVDKKDLSHIEEIIVGGPIKEAKHDILGLREKVLEHKEDLMEINSLDGAFAETKIAKDKLEDEKRNIREMLIDPTVENSVDLKKEREVRIQDVIDSLAKLKES----------GEQADDGEQRERIEALLKTIDE-DSD--TDVHVSAAQMASMIGT----LKKEDEVAGLTEEIRKVQSGNYQMPILPTGPSSADAFNQPQGVYTASKQVPARSEQEGVEQKQQVENGPVGIPDVDTKVTSTLQQNSSKTSSSSTTKSTSDSKSA................................................................................................................................................................................................................................................................................................................................................................... 784
33 -10.700[DZ] KOG2229 Protein required for actin cytoskeleton organization and cell cycle progression  ali follow..  8  501..DRGKNAAMEVQEAKKGGKDSKRPQFGADNSVQGIAGIELLAKWKKEHGEESENEDADANWEVDVDSEEDDVDGEWVTMDSDKEYDVDMEDSDDEKDNAKGKESDSDLELSDDDDEKEVKDEQEDADIDPEAAFREIASTRILTPADFAKLQELRNEESVAKIMGIHKQDKREELVDASTLTGPIK--YKQSREERLQKVLEGREGRDKFGSRRGKRDNMRSTTNREKERRKNFVMSIHKRSVRGKQKMSLRDKQKVLRAHITKQKKKG................................................................................................................................................................................................................................................................................................................................................................................................................................................. 766
34 -10.600[R] KOG2140 Uncharacterized conserved protein  ali follow..  10  655...VAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNS-----------SENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAE---------RRWEKSSRYSEQSRESKKNQDRRREKSPAKQK........................................................................................................................................................................................................................................................................................................................................................................................................................................... 908
35 -10.600[S] KOG1793 Uncharacterized conserved protein  ali follow..  12  1MSDHEEESHGASPTSPASSGASSPLAPISPRSEGNAPESPSGDVQDIYKDESFEAPASPARDSSAPASPSAASPAGSRSPSPSPVKTKSKVMIDSDEDSDAEESANKRALIDSDASDAEGKKRRVMLDSDDSDHEGTSKKEPTTKNLFGDDSDDDDEDRPKKTNDLDEFVEGRDEEESQE---------EWDFDKMLAEKKAERKKKTRRGGKDGGI-KSDRNANIERKPAFQKSALSEWALDIRIT........................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 316
36 -10.600[A] COG5213 Polyadenylation factor I complex, subunit FIP1  ali follow..  14  2..................................................................SNADQHMDVDEDEYLYGETIEERNDGVTVSNAKSPEQASEESDDSDIEFIIETKPGERAEPLGGSIATLGSTRPSAKPQVEKTAVEVKTTEPQDLSTAETAPKVDIDA----------DGKIFEIDLESFDDKP-----------------WRKDYFN---------------YGFDLRDDFSPQKF.................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 170
37 -10.500[S] KOG2422 Uncharacterized conserved protein  ali follow..  11  1MSGRLLKKVLQEHEDSKLQKHHEEEE--------------------EEDEEESGARSSINPFDLLNDGDEDPEEIDDETIAEKKNEDADHQSSVADHVQPVSKNKSKKKKKKKNKESGSNVPKAEMTLDETLEALGLNANSKQDKVQETKPNADSSKKASSRF--DSKYLNLENELRR-------GSKAMRSFESESGSQGGSSSRRGGRLVSPKENW-SSSYEQAQRALNGVASVLIHNPYHI........................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 264
38 -10.500[R] KOG2950 Uncharacterized protein involved in protein-protein interaction, contains polyproline-binding GYF domain  ali follow..  8  1........MKRTLRNPGNSSTVGDVHDVFFEYDVSNVGRKRPRTKEEGYYESESEEDEDQILNKEKKEGQSEDMFSDTSEDEKRTLPNDEAQKRRDFIENGDAERLAHKGLRNKEVLNDDSDDEDDNGKYSKLRYEDIEGQEDTNQANDLDADEEGSEISVPSSPKRMSFNLKEDMEEGDF-DENGNFIRKNYDPESQY----------------DAWLNGSVSNKKSIAAAREA.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 210
39 -10.500[R] KOG1400 Predicted ATP-dependent protease PIL, contains LON domain  ali follow..  13  4..EENSEINSVQARDEDVQLEDQQSQGLQDRQVDVIEQAWNNAMPDEPSPPAEDAFQDPLATDGEGGDALEAMVENVLQDDTASEGSHPSSDMSLESPGSEDDSDLESLPHWMIPQNRLRSAVDMMVSQARNSMVFSQERRRSRTSEETSQEAAEQPVDPPPQQPPRPPIDIGFDTNLPSYF......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 205
40 -10.400[U] KOG0946 ER-Golgi vesicle-tethering protein p115  ali follow..  6  698..KDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRLREEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTA-----IKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQKILSLKNKLKDLGHPVEEEDELESGDQEDEDDESEDPGKDLDH................................................................................................................................................................................................................................................................................................................................................................................................................................................ 961
41 -10.300[K] KOG4501 Transcription coactivator complex, P100 component  ali follow..  10  499LAQMDRQEVYIPPDPQDKQQRQTGLRHFNVHDGDRYDVLTRDQPECIIKQGKGLPGAPRNAEQLLDDKRDLKQLKERYQKYAMVEETTLERGEYDDEYDDSYEAQNEGQAPPVSLLRGRLQEAAQDELENDDEESSGGHSDPEPSMRTNRDFCENPEVIRARYEQRQLSKYGQKSGGHGASPSVVGA------PKGQGQSQQTQRSRGQKEAHKSTRANHNR---KAGAAFKRSK--GMMG.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 735
42 -10.300[O] KOG2062 26S proteasome regulatory complex, subunit RPN2/PSMD1  ali follow..  9  775..................................................................DKNLNAPKFSFISNVRPKLFAYPPKSVQPTAKTVQKVETAVLSTTVKAQARAKRAEREKASKGSNDDEMKIDKKTTEEKEATPMEMDEEKSQDISINGNSKKEEPKSETLENFTYYPTGGVLMLIDRESDKAPDLIELNRDAVPASADTEP------EQEASPPED-------FEYPFDDDD....................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 965
43 -10.300[O] COG5116 26S proteasome regulatory complex component  ali follow..  9  775..................................................................DKNLNAPKFSFISNVRPKLFAYPPKSVQPTAKTVQKVETAVLSTTVKAQARAKRAEREKASKGSNDDEMKIDKKTTEEKEATPMEMDEEKSQDISINGNSKKEEPKSETLENFTYYPTGGVLMLIDRESDKAPDLIELNRDAVPASADTEP------EQEASPPED-------FEYPFDDDD....................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 965
44 -10.200[A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP) subunit - Mpp10p  ali follow..  9  180..LEQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDE-----VKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGE-HFDHAVRTEETTLQLEDIIKQ--WDVRKEKPKEDAYEYKKR............................................................................................................................................................................................................................................................................................................................................................................................................................................................ 457
45 -10.200[O] KOG1645 RING-finger-containing E3 ubiquitin ligase  ali follow..  7  3.............................................................................PRRSYPFSGHGGTIARFIEFGEAFGHYGEEEDEEEEDEEEAYVDYGEVQEEDEEEEEEEDSERQTREYIDVLDSPVRVSQNESEGIENQNRRMSNGNKVTLRDCL-KSGILDSIV-----------------------VDTCMDIPASTSGFSSSLRDVRKIYASRVAAVDDEAHKRILFLEAKLRSIEQKTAS................................................................................................................................................................................................................................................................................................................................................................................................................................................ 193
46 -10.200[JU] KOG2153 Protein involved in the nuclear export of pre-ribosomes  ali follow..  9  22.............................LRGVKINDYFAENMGFASASREEKLKMLKTNKTRKTTKHLNRLAKRKKLSREIRDGMADIKSRKSADLRQRAVNIEDDFIADRQAHYENSDEDLPLDMMDADIDWENSAFANAKRRLEKKRSGVESDSDDEDDVEKKKRKFAGLLEEGHEELLPKDGTLIRPTREKEVKEDEEEKSGDEEEEGEEDEP-ASELIAKRRELMQEFKDTIASHANMLLSN........................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 250
47 -10.100[K] KOG1194 Predicted DNA-binding protein, contains Myb-like, SANT and ELM2 domains  ali follow..  12  2................................DSYTSSDEDASRKENISDEGLNMLNASPEPMEEDDPEEQAEQEEETSRMARPIRSMRKRETTSGESMGDEDEDLEDEEDEDEEAEAREHHESGAHDTSFSNPLSNVDNLIHGTEYQAIIQPTAEQLEKEPCRDQPDEMNENR-----EYISEATGRYQLPIDRAQSNDFDAAMVQAMRRKEIHDDWTAELFSTHAAMPRSLSSIIQYY-YNTKKVQNYKTMINVHLNETDTYDELFKEVNHLER........................................................................................................................................................................................................................................................................................................................................................................................................................................... 269
48 -10.100[J] KOG2409 KRR1-interacting protein involved in 40S ribosome biogenesis  ali follow..  14  38...RRLEEMQKIKDKYGDIDDDDSSSESEPEWTEGHEEAKDVQDAPSKPNNNPKKSKSEKSKKKDEKMTIKDYERKLVLEKGGQIDESDEEAEYNKTQQRGYYEEQEEIRKSLSAAINADDGADDDTSKEQEDEDEDFYQWMKSEDGKADKKKAKELKHLKKFWKDDKNMDESDK----DYLLNKD-YEPGENEENPTYEDIVALEEDEKDLDSNRKYEHKRFEDPDQEPRTVAE-------SMRSEDSSRKDKRHEREERKKREKAEKKKE............................................................................................................................................................................................................................................................................................................................................................................................................................................... 335
49 -10.000[J] COG5384 U3 small nucleolar ribonucleoprotein component  ali follow..  10  140..EAEIMNEEGQQIEQKKDAFGLNDGFFDIDNFNKQTLALEEEAVEEGVLGDEDDGIDLLMDPDENMEDSEDESNGPQADSIMYEDFFGPKTAAGRRELKKKKAESKRKRTSKPDFKNDVQQNVIEENNESSDNEYATFDRVKKDLFASDEEDDVSADQLSSYERDKARLTQQIRELEAENVAKKG--FETGAKPVPVQTEETTETLEDLIKN---RIISKTFDDVPKR-KSQRSLAEEYEEEFLKKSNADTYKSEADKK........................................................................................................................................................................................................................................................................................................................................................................................................................................................... 433
50 -9.870[S] KOG4346 Uncharacterized conserved protein  ali follow..  8  243.............................................VELIFNFIALPDAKEDDRLRFEYDSFKDTFHWHIFEEFDELGQFESPSKTKLDEKPCEDQLKQLELHLSDFMSTTEQKEPHKPNIEIQANPAPENQNVNMQLDSDDDEPLDEDDDELKPYDMSNDTTTTIDQRPKFVIDLLHLLREKVENYQVFEGALGTAEQGQLAKHEMQFYYEQFERTQFKPGPCAEYLCR-FYSASVR--AATAKELSGDENMQNEMEIVDVIPPAAKHPRKFEFQQEEESPAARLAAAQRIIRDRLRAKTKRYFSKPKAGDQMEKANP....................................................................................................................................................................................................................................................................................................................................................................................... 563
51 -9.860[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  11  467VSDAAAGEYSSAIETLVTAISLIKQSKVAHDERSSLQDTLHGIEAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIGRPKSA------------AVAGGSMEKPRGQSAWDIIDTDA----HWI--IKQQIPAPPS---SQQNFNI........................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 699
52 -9.820[K] KOG1598 Transcription initiation factor TFIIIB, Brf1 subunit  ali follow..  8  293.SYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGELDLSGIDDLEIDRYILNESEARNAEYLREQ----EKEARIAKEKELGIYKEHKPKKSCKRRE-------EAIEKMLEQKKISSKINYSVLRGSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEEADEEEPDEEDGEPCVS.......................................................................................................................................................................................................................................................................................................................................................... 657
53 -9.730[N] COG3351 Putative archaeal flagellar protein D/E  ali follow..  9  89..VEALEEKKFAVHEKKAESIAEKAAEVTEKVERIEELLEEKPKEEKSELAKKVEEIHKKVEELEEKLTGEKLEETKKKVEELEEKIEKGEEVTAEEVGELAEKVEELEAEAAKPEEEVVVEVPEEEEKVEVVEEEVPPEEEEVVTPEVEVVEEEKKEEVEEEKEKEEVGKMSEKMKIPE---------DIASILFEEEPKKARLEEIPEDVVSI-KW---GFLIDRVGIQNLEKVLEFYGWKVLNQ........................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 331
54 -9.690[O] COG5243 HRD ubiquitin ligase complex, ER membrane component  ali follow..  9  322.............................................................................................................................RNNKQLDDTLVTVTVEQLQNSANDDNI--------DELIHSPNQQTWKNKNKKPKRLP--GHIL-HLS-----------------------NW----MERSQTCPICRLPVFDEKGNVVQTTFTSNSDITTQTTVTDSTGIATDQQGFANEVDLLPTRTTSPDIRIVPTQNIDTLAMRTRSTSTPSPTWYTFPLHKTGDNSVGSSRSAYEFLITNSDEKENGIPVKLTIENHEVNSLHGDGGEQIAKKIVIPDKF................................................................................................................................................................................................................................................................................................................................... 547
55 -9.670[S] KOG2827 Uncharacterized conserved protein  ali follow..  11  200MASVDEEAKQARKEQELKEKRKAKLEKLTAGPAKHMFEDQDYLSRREEIINKTEDACEAGFALMLEMKRNSRKSKEQENKNDEDEDDDVNAEDVTDLFNDRGGRKRKIAAPSIGEDGGNKRINDESDDSEDDSENEVDPEELEAIRQYFEAKKQDEKDNGEGTSEAVPEVLVDEQEIEPA-----------RPRLDSASNIDDLPKIDVKTPCEYGPISLDDFTSAEDLEHLKSALNDR-GWCVKGREYPKNILTPELKKKIAEEEEAERK................................................................................................................................................................................................................................................................................................................................................................................................................................................ 488
56 -9.670[KB] COG5137 Histone chaperone involved in gene silencing  ali follow..  12  115..............................NNEMEGLNLQEMDDAEIKKVKVDISKVWRSILAEKPRVTRFNIQWDNPDFDDAPPVQPDADEEEEEEEADEMEEEFDEEGEGDEEEEEEDDGDGDGEGDGDGEGENDGKGSEEEEEEEIDIEEEEEESALANASAAEEKPEEKPETSQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 262
57 -9.620[K] KOG2406 MADS box transcription factor  ali follow..  7  447....QDRYGPKKLYKPNGQMNAEEFTKQLAEFLDRQSNYEGIEHRGLEEPELDSDDDEPPPQANGSTGLTAKVKKNPSMRKACQRNSVIQPEEPDSTHVRNFLDFVIPEDNWDSTSEMSDYADEDDMESNLNALSGGGSVFPLDRQIQSYMEQMDRELAQTSVGKSFHGKKKTAPQA--------------DEDDFDDIEDFEPININVNTLRN------DSYQSQVAGPVSN--LFSAMGVGMSAVEDKEQKDISESA............................................................................................................................................................................................................................................................................................................................................................................................................................................................ 683
58 -9.620[B] KOG3118 Disrupter of silencing SAS10  ali follow..  11  3...............................................................RKKSRSSSTRKGSSLKVPEIKEKEKINAINTYEDVANSEDEFYNAQDK---------DADNGEQADELELSDEELVALESSSDEEDGNAEENLSENEELSGKKKDAVNEEELYDNKGWGRSAKSYYGGDDYDNEDYSEEDDEFDARM--------------EEQEALRLQRKRLE----KVSETD....................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 163
59 -9.600[K] KOG3248 Transcription factor TCF-4  ali follow..  15  297.......................................................................................................................................................KQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKK-NAFYMKEMRAKAECTLKESAAINQILGR---RWH--ALSREEQAKRKERQLMQLYGWSARDNYGKKKKRKRDKQP........................................................................................................................................................................................................................................................................................................................................................................................................................................................... 412
60 -9.570[S] KOG3114 Uncharacterized conserved protein  ali follow..  11  3..........................................................................MSGGSYTNIDHQKVSGSVPAVPDPGHVTVKFADSNLQTFPPSATQGKISGGTNPPRDADVLYALLANLIDFQPVADTFSRPVNGTTDEPQSSGWDVDTSDERLKESLFPFRGTFTEKTANNPD----IGTFVTYIAHKLKKQEWNYDVVLKYFSAPSGLVQLFCLYGYSL........................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 223
61 -9.550[K] KOG3794 CBF1-interacting corepressor CIR and related proteins  ali follow..  10  295..DPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSH------------HRERKQVHSNDPVSEKSQKQHYSESGK--IQRVEKEHRYDERRHR---------VDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRVIGEQVRKSMSLIHRRLYRISGLSSVNAWNLQIREAVNRNDPVE............................................................................................................................................................................................................................................................................................................................................ 641
62 -9.510[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  10  642....GAARQELMNRPISELERRCRHNGLSLLGGREMMVARLVCLKDAEKQRGYEVVDENAKYRQGHSTWEEVNIEPKRMKTSYDKVETEEPVDLASTIPIPQPELKAFVKKEKIDLILPTSRWAREDDETDDEQKKSYSSGSDNAGGITFKTDEEDLKADPSVRVQPENEIDVEQRQKLRHIEIALIEYRESLEEQGMKNSEE----------------------ERKVAIHRKRLEADGLSGNQRVLPEKREKREDSRDSSRKRNRSESQNRSQSPPQKSLTRERVRDHDLDKDRHRDRDRQQHDLDKDRKRRAKSSSRERDDHDRSRERDRDWRRRGMR.......................................................................................................................................................................................................................................................................................................................................................................... 957
63 -9.500[S] KOG2236 Uncharacterized conserved protein  ali follow..  15  1MSDDLFSKALENPDQDLNVELPKDDVDLGLLGDGGNERKTD-----------------EPVADAERSTGLGSGSSESESDSGSDSDSDSGSSGSEDDSADQDVEGEDEGGDAIENEDEDEDPSPSGPILSKNEILEETVPELPEDYEISEKTI------HATMSGEKRVLKEGEDRTNPFYRIKLGEFIVTPDAH---------TFELKRNKGTDASNGYD-----EELPEEEQE------FS--DDEKEALFKKMKKQQRQRKKRDNRKLANDSDNVKVKRARQPKANSLPKLV........................................................................................................................................................................................................................................................................................................................................................................................................................ 305
64 -9.450[L] KOG2310 DNA repair exonuclease MRE11  ali follow..  8  468NLQETRGKLAKDSDAKKFEEDDLILKVGECLEERLKDRSTRPTGSSQFLSTGLTSENLTKGSSGIANASFSDDEDTTQMSGLAPPTRGRRGSSTANTTRGRAKAPTRGRGRGKASSAMKQTTLDSSLGFRQSQRSASAAASAAFKSASTIGEDDVDSPSSEEVEPEDFNKPDSSSEDDES------------TKGKGRKRPATTKRGRGRGSGTSKR-------RKNESSSSLNRLLSSKDDDEDEDDEDREKKLNKSQPRVTRNYGALRR................................................................................................................................................................................................................................................................................................................................................................................................................................................ 720
65 -9.410[S] KOG4365 Uncharacterized conserved protein  ali follow..  10  93...EGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHPEDKPTGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQ-FRMDSRFLETDSEEEQEEVNEKKTAEEE-------ELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKK.............................................................................................................................................................................................................................................................................................................................................................................................................................................................. 356
66 -9.410[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  7  184.ADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRS-----------PKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEK---------RERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMSD.............................................................................................................................................................................................................................................................................................................................................................................................. 484
67 -9.370[R] KOG3175 Protein phosphatase 4 regulatory subunit 2 related protein  ali follow..  12  246.KRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 417
68 -9.310[BD] KOG4563 Cell cycle-regulated histone H1-binding protein  ali follow..  8  311.GDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDK---------EEMPNDSVLENKSLQENEEEEIGNLELAWD-DL--KRQETKEAQLYAAQAHG-EVSVESE...................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 556
69 -9.240[K] KOG2473 RNA polymerase III transcription factor (TF)IIIC subunit  ali follow..  9  354LFELDDEYIQQEIRKPPKQTTCNYKTGVSVFPEPGFEDVFKSIQEEFERSEKTRIQKDALQPSQRNHQETTKDMKKCKNTNKEKDDDVNADEDSEDLDDEYEEAANDDDISISSHGYGDMENNSRTYLQGLFNRFPSSASALYGSANDDNDSDGEYPIYEQESNALDDDEEDDE................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 545
70 -9.230[JU] COG5117 Protein involved in the nuclear export of pre-ribosomes  ali follow..  10  1MAKRNRSQFRIQERTAKKRKHEDSLLEGNVFQNAPEDMDENTIYSAKGSSWDEEEQDYEMVPRKNRSDTSNLVEG--KVNGKVERKLHKAQEKPKDDDEEDEDSNDSSEDDEGPNEEQEAEAKEDEPDTEEKILQLKEDIADLVTKVMEEPEENTAALGR--------KMVESKNPN--SIIP------GYRIRPLTETEKKEKVSKEVSKLRNFEQALVYNYKNGILATQAAKELIST--FNFRTD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 271
71 -9.110[S] KOG4843 Uncharacterized conserved protein  ali follow..  8  252.YTRDTKFDRENQNYNEQKGEIKMEKEGHAHLAWKEQKDYHRGKRVAEGSTANVDPWVVSRGNPQGPTEVGPKDLSAPVEGSHLEGRETVGENKVDAKNEDRFKEKDKKRKELKHREWGDRDKDRNDRRVSVLVGSVMSEPKEIGREERESDRWERERMEQKDRERNKEKDKDHIKREPR---------TGAEKEISQNEKELGEASAKPSEQEYVAPEQKKQNEPDNCEKDERE-------EKRRERDGDSEAERAEKRSRISEKESEDGCLEGEGATEREKDAFNYGVQQRKRALRPRGSPQTTNRDNVRSRSQDNEGVQGNHSFLYPQERIKLHCLENNSKSEVS................................................................................................................................................................................................................................................................................................................................................................... 584
72 -9.080[TR] KOG2268 Serine/threonine protein kinase  ali follow..  7  309KEMEQDLLEEYGMVDQADEEDEGEDLEEEEEPPTLVTAASVEIDECRRQVENEVIYSEAKPTQKSDDAVRRYIESCTQYLGNLSVGPEVPDQTMPKKLDISLPAETPDVIPFEAETSATNTVEEDVKSISSNDLDTDEVPELVGLDPNSRMYRLKMVEQMLNDARSQRSYSTTTSTIAPSVITDR-------IRRNMDIKEKREQRKKCVAKGEASAVHRHR--------KENKDVVKEYGWD............................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 537
73 -9.000[A] COG5182 Splicing factor 3b, subunit 2  ali follow..  9  3LLTRPKHCCLDFLLMAEIQTAQNPLKELEKILERNNKQKNKKSRNQVRREKKKLLREKTNSGAKLAEKNSDDKDQLTENNDNLYNDKKSNGNFYDTNKTDSVDGMVYTTIVDSVELDPNDPKADGQEKDFEDTDKGQIMYSDDEILSEGEEDALQKQQEEKLSKKKLRKLK-DVSSLDPLFVPR------H--------------------------WNQKRYLSGERQLFELPSYIRATGIQMRNAVHENEADMPLRQKMRERVQPKMGK................................................................................................................................................................................................................................................................................................................................................................................................................................................ 290
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Jaroszewski L, Li W, Godzik A. A segment alignment approach to protein comparison. Bioinformatics. 2003 Apr 12;19(6):742-9.