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Query: [PET] KOG4440 NMDA selective glutamate-gated ion channel receptor subunit GRIN1, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSTMRLLTLALLFSCSVARAACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEGRAAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGILGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKATFRAITSTLASSFKRRRSSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRESLast
1 -198.000[PET] KOG4440 NMDA selective glutamate-gated ion channel receptor subunit GRIN1  ali  100  1MSTMRLLTLALLFSCSVARAACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEGRAAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGILGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKATFRAITSTLASSFKRRRSSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES 938
2 -152.000[PET] KOG1052 Glutamate-gated kainate-type ion channel receptor subunit GluR5 and related subunits  ali follow..  22  10NPVFRRTVKLLLCLLWIGYSQGTTHVLRFGGIFEYVESELAFRFAVNTINRNRTLLNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFG-----PSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKD--SFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYN--LRLKIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRITTDAALMYDAVHVVSVAVQQFPQMT-----VSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQK---GKPANITDSLSNRSLIVTTILEEPYVLFK-------------------------------KSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQ----DDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSNNFTLLNSFWFGVGALMQQGSE-LMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTK---IEYGAVEDGATMTFFKKSSTYDKMWAFMSSVLVKSNEEGIQRVLTS-DYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRRLPGKETMA..................................... 908
3 -149.000[PET] KOG1054 Glutamate-gated AMPA-type ion channel receptor subunit GluR2 and related subunits  ali follow..  21  1..MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPQSQEHAAFRFALSQLTEPPKL----LPQIDIVNISDSFEMTYRFCSQF-SKGVYAIFG-----FYERRTVNMLTSFCGALHVCFITPSFPVDT-----SNQFVLQLRPE---LQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLD-TAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDNPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDSIRKIGYWNEDDKFVPAATDAQAGGDNSSV----QNRTYIVTTILEDPYVMLK-------------------------------KNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGAR----DPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRSNEFGIFNSLWFSLGAFMQQGCD-ISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTE---IAYGTLEAGSTKEFFRRSKVFEKMWTYMKSAFVRTTEEGMIRVKSKGKYAYLLESTMNEYIEQRKCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWDKGECGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK-GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMPLGATG......................... 905
4 -24.500[ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain  ali follow..  15  43.................................................................................................................................................................................................................................................................................................................................................................................................................................................................NSQGELVGFDIDLAKELCKRINTQCTFVENP-----------------LDALIPSLKAKKIDAIMSSLSITEKRQQEIAFTDKLYAADSRLVVAKNSDI-------------------------------------------------------------------------------------------------------------------QPTVESLK--GKRVGVLQGTTQETFGNEHWAPKG--------IEIVSYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQ-GPSVKDEKLFGVGTGMGLRKEDNLREALNKAFAEMRADGTYEKLAKKYFDFD.............................................................................................................................................. 256
5 -17.500[E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component  ali follow..  10  10GGRKYEKDHSGALAALATSVAAQADTIKVGVVGPGKNFKAGIDAYMAVNGAKVGDDDIEI-IYRDVPQADPAQSKALAQELVVKEGVQYLAG-----FYFTPDAMAVTPLLEQANVPLVIMNAATSAIVTKS--PLVVRTSFTLWQTSTPIAKVAKDAGVSKIISVVSDYGPGVDAENAFKAGFEAAGGEIVEAIRMPLSTNDFSPIMQRIKDSGAEGVFAFLSGPTTLGFVKSFNENGLKDGGIKFFAPGDLTQESDLPALGDAALGLNPAELSFPAVGAYDGMHVIYKMIEATGGE------------------QDAQKAVDAVKGLSWTSPRGPVSIDPESRHITQNIYLREVAKAD.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 379
6 -10.300[P] KOG3684 Ca2+-activated K+ channel proteins (intermediate/small conductance classes)  ali follow..  11  417....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LIARVMLLHSKLFTDASSRSIGALNKINFNTRFV---MKTLMTI-----------CPGTV-LLVFSISLWIIAAWTVRACER----------YHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIK--------NAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDL-----ITELNDRSEDLEKQIGSLESK--LEHLTASFNSLPLLIADTLRQQQQQLLS.............................................................................................................................. 690
7 -9.040[M] COG4623 Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein  ali follow..  12  18.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................FGLDYELAKQFADYLGVKLKVTVRQN----------------ISQLFDDLDNGNADLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQ----LTVAPGHVVVNDLQTLKETKFPELSWKVDDKKGSAE----------LMEDVIEGKLDYTIADSVAISLFQRVHPELAVALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDG-TLARIEEKYLGHGDDFDYVDTRTFLRAVDAVLPQLKPLFEKYAEE-LAAIAYQESHWDAQATSPTGVRGMMMLTKNTAQSLGITDRTDAEQSISGGV-------YLQDMMSKVPESVPENER--AAYNMGYAHMLDARALT----VKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLFSRKGSE.......... 468
8 -8.960[P] KOG0501 K+-channel KCNQ  ali follow..  9  261.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................FLVDIV--------LNFHTTFVGPA--------------------GEVISDPKLIRMNYLK-------VIDLCLPYVDEGISSLFSSLKRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMAFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQ-NRYHEMLNSVRDFLKLYQ-------------VPKGLSERVMIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQD-----------DEVVAILGKGDVFGDVFWKEATTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNVLTEHASAN 752
9 -8.960[R] COG3107 Putative lipoprotein  ali follow..  9  314...................GVASPAQASVSDLTGEQPAAQPVPVSAPATAAVSAPANPSAELKIYDTSSQP---LSQILSQVQQDGASIVVG-----PLLKNNVEELL--KSNTPLNVLALNQPENIENRVNICYFAL----SPEDEARDAARHIRDQGKQAPLVLIPRSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGAVYIVATPGEIAFINGSQSGATLYASSRSMLAGGNLPLMQQALSAVNNDYSLARMY-----AMGVDAWSLANHFSQ-----------------------------MRQVQGFEINGNTGSLTANPDCVINR-NLSWLQYQQGQVVPVS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 678
10 -8.720[PT] KOG0500 Cyclic nucleotide-gated cation channel CNGA1-3 and related proteins  ali follow..  9  214.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................YVLDVL--VRARTGFLEQGLMVSDTN-----------------RLWQHYKTTTQFKLDVLSLVP-----TDLAYLKVGTNYPEVFNRLLKFSRLFEFFDRTETNLVLYILIIIHWNACIYFAISKFIGFGYPNISIPEHGRLSRKYIYSLYWSTLTLTTIGETPP-PVKDEEYLFVVVDFLVGVLIFATIVGNVGSMIS-AEFQAKIDSIKQMQFRKVTKDLE-------------RVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIFQDCEVFSPGDYICKKGYIINEGKLAVVADDGVTQFVVLSDGSYFGEIS---LNIKGSKSGNRRTANIRSIGYSDLFCLS------DLMEALTEYPEAKKALEEKGRQILMKDNLIDEELARAGADPKDLEEKVEQLGSSLDTLQTRFARLLAEYNATQMKMKQRLSQLESQVKGGGDKPLADGEVPGDATKTEDKQQ 694
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.