current user: public

If you have questions about the server, please let us know.

Query: [R] KOG4578 Uncharacterized conserved protein, contains KAZAL and TY domains, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430
# Score Template Links and tools%idFirst MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEGRLVLast
1 -156.000[R] KOG4578 Uncharacterized conserved protein, contains KAZAL and TY domains  ali  100  1MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEGRLV 434
2 -52.100[W] KOG4004 Matricellular protein Osteonectin/SPARC/BM-40  ali follow..  15  1MRALLCLAG-----------------------RALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAEETEEEVVAEN----PCQN-------------------HCKHGK-----VCENNTPMCVCQDP------------------------------------------------------------------------------------------------TSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPDGYLSHTELAPLRAPL---IPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQDKDLV 302
3 -31.400[R] KOG3555 Ca2+-binding proteoglycan Testican  ali follow..  13  99...KVCIAQDSQTAVCISHRRLTHRMKEAGVDHRQWRGPILSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHCPCPSDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELRSIYLD-----KNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYMPTQCHGSVGQCWCVD-RYGNEVMGSRING-VADCAIDFEISGDFASGDFHEWTDDEDDEDDIMN-----------------------------------------------DEDEIEDDDEDEGD-------------------------DDDGDHDVYI................ 436
4 -16.900[R] KOG0038 Ca2+-binding kinase interacting protein (KIP) (EF-Hand protein superfamily)  ali follow..  13  118..................................................................................................................................................................................................................................................................................................................................................................SEQAPRDIKVFYAFKIYDFDQDGFIGHADLMSCLTTMTKNEEHQQIADKVIEEADVDGDGKLSILEFEHVILRAPD.... 197
5 -15.900[T] KOG0044 Ca2+ sensor (EF-Hand superfamily)  ali follow..  24  93...................................................................................................................................................................................................................................................................................................................................................................SRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIR--GAKSDPSIV 180
6 -15.800[T] KOG0034 Ca2+/calmodulin-dependent protein phosphatase (calcineurin subunit B), EF-Hand superfamily protein  ali follow..  16  147...................................................................................................................................................................................................................................................................................................................................................................PYASIQEKTDFAFRLYDLRQTGFIEREEVQQMVSAILLEELLTMIIDKTFADADSDKDGKISKDEWNV--YVHKHPSLL 230
7 -15.800[TZDR] COG5126 Ca2+-binding protein (EF-Hand superfamily)  ali follow..  25  93...................................................................................................................................................................................................................................................................................................................................................................SRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMATPEMRVKKIFKLMDKNEDGYITLDEFRE--GSKVDPSII 180
8 -14.200[TU] KOG4223 Reticulocalbin, calumenin, DNA supercoiling factor, and related Ca2+-binding proteins of the CREC family (EF-Hand protein superfamily)  ali follow..  13  148....................................................................................................................................................................................................................................................................................................................................................YLGNPAEFHDSSDHHTFKKMLPRDERRFKAADLNGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIA-RDLNKDGKL. 264
9 -12.400[T] KOG0027 Calmodulin and related proteins (EF-Hand superfamily)  ali follow..  13  14....................................................................................................................................................................................................................................................................................................................................TKKPQTGRKISTSSRGTIHSQQSQPEDIQMKYTRKELKEYRQLFNMFDTDGSGAIGNEELKQAMISIGLHANKAE-IDNVIKEVDADGNGEIDFEEFCACMKKSQN.... 118
10 -11.800[ZD] KOG0028 Ca2+-binding protein (centrin/caltractin), EF-Hand superfamily protein  ali follow..  12  116....................................................................................................................................................................................................................................................................................................................................EEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEE-LREMIDEADLDNDGEVNQEEFLRIMKKTS..... 219
11 -11.100[Z] COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily)  ali follow..  13  7.............................................................................................................................................................................................................................................................................................................................................................QKKYPELTNEEILTLTDQFNKLDVDGKGYLDQPTTIKAFEDSKKGSYDE--VREAIREVNVDSSGRVEPEDFVGIFNVLKKGV.. 87
12 -10.700[U] KOG1955 Ral-GTPase effector RALBP1  ali follow..  14  200..................................................................................................................................................................................................................................................................................................................................................DQTTVRTVASATTAIEIRRQSSSYDDPWKFKTIQPDLNGFIPGSAAKEFKSKLPILE-----LSHIWELSDFDKDGALTLDEFCAAFHLRKNGYDL 307
13 -10.000[P] KOG2643 Ca2+ binding protein, contains EF-hand motifs  ali follow..  236..........................................................................................................................................................................................................................................................................................................................................FLRSFTPGVMQPRRWGLDSFKNYNPEKHKRHKFSDPDSIFYKLGENGLINFSDYLFLMTLLSTSHADFALA---FKIFDVDGNGALDKEEFTKVQQL....... 329
14 -9.500[Z] KOG0031 Myosin regulatory light chain, EF-Hand protein superfamily  ali follow..  93...................................................................................................................................................................................................................................................................................................................................................................KGADPEDVITGAFKVLDPEGKGTIKKKFLEELLTTQCDRFSQEE-IKNMWAAFPPDVGGNVDYKNICYVITHGDAKD.. 168
15 -9.440[T] KOG0037 Ca2+-binding protein, EF-Hand protein superfamily  ali follow..  40.....................................................................................................................................................................................................................................................................................................................GPAYSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNA--------KENFMTVDQDGSGTVEHHELRQAIGYRLSPQTL 160
16 -9.400[S] KOG0043 Uncharacterized conserved protein, contains DM10 domain  ali follow..  584..........................................................................................................................................................................................................................................................................................................................................................AAAHLELKRTLWNARDDLMEHFHHINPTNQPFLPEVKVRSALRGCRLPFSLEL-IDNILSILNRNECDDIEVCDLMNFIDVSCGK... 667

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 4 7 0   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Wooley JC, Godzik A. Probing metagenomics by rapid cluster analysis of very large datasets. PLoS ONE. 2008;3(10):e3375. Epub 2008 Oct 10.